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  1. Genetically-modified (GM) mosquitoes have been proposed as part of an integrated vector control strategy for malaria control. Public acceptance is essential prior to field trials, particularly since mosquitoes...

    Authors: John M Marshall, Mahamoudou B Touré, Mohamed M Traore, Shannon Famenini and Charles E Taylor
    Citation: Malaria Journal 2010 9:128
    Content type: Research Published on:

  2. The complete sequences of the mitochondrial genomes (mtDNA) of members of the northern and southern genotypes of Anopheles (Nyssorhynchus) darlingi were used for comparative studies to estimate the time to the mo...

    Authors: Marta Moreno, Osvaldo Marinotti, Jaroslaw Krzywinski, Wanderli P Tadei, Anthony A James, Nicole L Achee and Jan E Conn
    Citation: Malaria Journal 2010 9:127
    Content type: Research Published on:

  3. Malaria is a significant public health concern in Afghanistan. Currently, approximately 60% of the population, or nearly 14 million people, live in a malaria-endemic area. Afghanistan's diverse landscape and t...

    Authors: Farida Adimi, Radina P Soebiyanto, Najibullah Safi and Richard Kiang
    Citation: Malaria Journal 2010 9:125
    Content type: Research Published on:

  4. There is an urgent need to identify new anti-malarial drug targets for both prophylaxis and chemotherapy, due to the increasing problem of drug resistance to malaria parasites. In the present study, the aim wa...

    Authors: Ali Ramazani, Sedigheh Zakeri, Soroush Sardari, Nastaran Khodakarim and Navid Dinparas Djadidt
    Citation: Malaria Journal 2010 9:124
    Content type: Research Published on:

  5. Malaria kills. A single rectal dose of artesunate before referral can reduce mortality and prevent permanent disability. However, the success of this intervention depends on caretakers' adherence to referral a...

    Authors: Daudi O Simba, Deodatus C Kakoko, Marian Warsame, Zul Premji, Melba F Gomes, Goran Tomson and Eva Johansson
    Citation: Malaria Journal 2010 9:123
    Content type: Research Published on:

  6. Prior studies have shown that annual entomological inoculation rates (EIRs) must be reduced to less than one to substantially reduce the prevalence of malaria infection. In this study, EIR values were used to ...

    Authors: Ayesha M Shaukat, Joel G Breman and F Ellis McKenzie
    Citation: Malaria Journal 2010 9:122
    Content type: Research Published on:

  7. In Ethiopia, the utilization of long-lasting insecticide-treated bed nets (LLITN) is hampered by behavioural factors such as low awareness and negative attitude of the community. The aim of this study was to p...

    Authors: Amare Deribew, Fessehaye Alemseged, Zewdie Birhanu, Lelisa Sena, Ayalew Tegegn, Ahmed Zeynudin, Tariku Dejene, Morankar Sudhakar, Nasir Abdo and Fasil Tessema
    Citation: Malaria Journal 2010 9:121
    Content type: Research Published on:

  8. Malaria is a major public health burden in Southeastern Bangladesh, particularly in the Chittagong Hill Tracts region. Malaria is endemic in 13 districts of Bangladesh and the highest prevalence occurs in Khag...

    Authors: Ubydul Haque, Ricardo J Soares Magalhães, Heidi L Reid, Archie CA Clements, Syed Masud Ahmed, Akramul Islam, Taro Yamamoto, Rashidul Haque and Gregory E Glass
    Citation: Malaria Journal 2010 9:120
    Content type: Research Published on:

  9. Populations of East Africa including Sudan, exhibit some of the highest indices of genetic diversity in the continent and worldwide. The current study aims to address the possible impact of population structur...

    Authors: Nahid A Eid, Aymen A Hussein, Abier M Elzein, Hiba S Mohamed, Kirk A Rockett, Dominic P Kwiatkowski and Muntaser E Ibrahim
    Citation: Malaria Journal 2010 9:119
    Content type: Research Published on:

  10. Premature death of Plasmodium-infected erythrocytes is considered to favourably influence the clinical course of malaria. Aurothiomalate has previously been shown to trigger erythrocyte death or eryptosis, which ...

    Authors: Ioana Alesutan, Diwakar Bobbala, Syed M Qadri, Adriana Estremera, Michael Föller and Florian Lang
    Citation: Malaria Journal 2010 9:118
    Content type: Research Published on:

  11. Accurate malaria diagnosis is mandatory for the treatment and management of severe cases. Moreover, individuals with asymptomatic malaria are not usually screened by health care facilities, which further compl...

    Authors: Bruno B Andrade, Antonio Reis-Filho, Austeclino M Barros, Sebastião M Souza-Neto, Lucas L Nogueira, Kiyoshi F Fukutani, Erney P Camargo, Luís MA Camargo, Aldina Barral, Ângelo Duarte and Manoel Barral-Netto
    Citation: Malaria Journal 2010 9:117
    Content type: Research Published on:

  12. Magnetic fractionation of erythrocytes infected with Plasmodium falicparum has several research uses including enrichment of infected cells from parasite cultures or enhanced detection of P. falciparum gametocyte...

    Authors: Stephan Karl, Timothy ME Davis and Tim G St Pierre
    Citation: Malaria Journal 2010 9:116
    Content type: Research Published on:

  13. Malaria is still a major public health problem in Brazil, with approximately 306 000 registered cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria occurred each yea...

    Authors: Joseli Oliveira-Ferreira, Marcus VG Lacerda, Patrícia Brasil, José LB Ladislau, Pedro L Tauil and Cláudio Tadeu Daniel-Ribeiro
    Citation: Malaria Journal 2010 9:115
    Content type: Review Published on:

  14. In Burundi, malaria is a major public health issue in terms of both morbidity and mortality with around 2.5 million clinical cases and more than 15,000 deaths each year. It is the single main cause of mortalit...

    Authors: Hermenegilde Nkurunziza, Albrecht Gebhardt and Jürgen Pilz
    Citation: Malaria Journal 2010 9:114
    Content type: Research Published on:

  15. Due to the spread of pyrethroid-resistance in malaria vectors in Africa, new strategies and tools are urgently needed to better control malaria transmission. The aim of this study was to evaluate the performan...

    Authors: Vincent Corbel, Joseph Chabi, Roch K Dabiré, Josiane Etang, Philippe Nwane, Olivier Pigeon, Martin Akogbeto and Jean-Marc Hougard
    Citation: Malaria Journal 2010 9:113
    Content type: Research Published on:

  16. Plasmodium vivax and Plasmodium falciparum are the major causative agents of malaria. While knowledge of the genetic structure of malaria parasites is useful for understanding the evolution of parasite virulence,...

    Authors: Lubna Khatoon, Frederick N Baliraine, Mariangela Bonizzoni, Salman A Malik and Guiyun Yan
    Citation: Malaria Journal 2010 9:112
    Content type: Research Published on:

  17. Malaria is rampant in Africa and causes untold mortality and morbidity. Vector-borne diseases are climate sensitive and this has raised considerable concern over the implications of climate change on future di...

    Authors: Henri EZ Tonnang, Richard YM Kangalawe and Pius Z Yanda
    Citation: Malaria Journal 2010 9:111
    Content type: Review Published on:

  18. Metabolic changes in the host in response to Plasmodium infection play a crucial role in the pathogenesis of malaria. Alterations in metabolism of male and female mice infected with Plasmodium berghei ANKA are re...

    Authors: Angika Basant, Mayuri Rege, Shobhona Sharma and Haripalsingh M Sonawat
    Citation: Malaria Journal 2010 9:110
    Content type: Research Published on:

  19. Malaria continues to be a major public health problem in remote forested areas in Cambodia. As a national strategy to strengthen community-based malaria control, the Cambodian government has been running the V...

    Authors: Junko Yasuoka, Krishna C Poudel, Kalpana Poudel-Tandukar, Chea Nguon, Po Ly, Duong Socheat and Masamine Jimba
    Citation: Malaria Journal 2010 9:109
    Content type: Research Published on:

  20. At a recent meeting (Sept 18, 2009) in which reasons for the limited access to artemisinin-based combination therapy (ACT) in sub-Saharan Africa were discussed, policy and market surveys on anti-malarial drug ...

    Authors: Graciela Diap, John Amuasi, Isaac Boakye, Ann-Marie Sevcsik and Bernard Pecoul
    Citation: Malaria Journal 2010 9(Suppl 1):S1
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  21. Malaria microscopy and rapid diagnostic tests are insensitive for very low-density parasitaemia. This insensitivity may lead to missed asymptomatic sub-microscopic parasitaemia, a potential reservoir for infec...

    Authors: Nicolas Steenkeste, William O Rogers, Lucy Okell, Isabelle Jeanne, Sandra Incardona, Linda Duval, Sophy Chy, Sean Hewitt, Monidarin Chou, Duong Socheat, François-Xavier Babin, Frédéric Ariey and Christophe Rogier
    Citation: Malaria Journal 2010 9:108
    Content type: Research Published on:

  22. The World Health Organization has recommended that anaemia be used as an additional indicator to monitor malaria burden at the community level as malaria interventions are nationally scaled up. To date, there ...

    Authors: Don P Mathanga, Carl H Campbell Jr, Jodi Vanden Eng, Adam Wolkon, Rachel N Bronzan, Grace J Malenga, Doreen Ali and Meghna Desai
    Citation: Malaria Journal 2010 9:107
    Content type: Research Published on:

  23. Anopheles culicifacies is the major vector of both falciparum and vivax malaria in Sri Lanka, while Anopheles subpictus and certain other species function as secondary vectors. In Sri Lanka, An. culicifacies is p...

    Authors: Pavilupillai J Jude, Sangaralingam Dharshini, Muthuladchumy Vinobaba, Sinnathamby N Surendran and Ranjan Ramasamy
    Citation: Malaria Journal 2010 9:106
    Content type: Research Published on:

  24. Afghanistan's national guidelines recommend chloroquine for the treatment of Plasmodium vivax infection, the parasite responsible for the majority of its malaria burden. Chloroquine resistance in P. vivax is emer...

    Authors: Ghulam Rahim Awab, Sasithon Pukrittayakamee, Mallika Imwong, Arjen M Dondorp, Charles J Woodrow, Sue Jean Lee, Nicholas PJ Day, Pratap Singhasivanon, Nicholas J White and Faizullah Kaker
    Citation: Malaria Journal 2010 9:105
    Content type: Research Published on:

  25. Applying the switch from presumptive treatment of malaria to new policies of anti-malarial prescriptions restricted to parasitologically-confirmed cases is a still unsolved challenge. Pragmatic studies can pro...

    Authors: Jean-François Faucher, Patrick Makoutode, Grace Abiou, Todoégnon Béhéton, Pascal Houzé, Edgard Ouendo, Sandrine Houzé, Philippe Deloron and Michel Cot
    Citation: Malaria Journal 2010 9:104
    Content type: Research Published on:

  26. The Malaria Clinical Trials Alliance (MCTA), a programme of INDEPTH network of demographic surveillance centres, was launched in 2006 with two broad objectives: to facilitate the timely development of a networ...

    Authors: Bernhards R Ogutu, Rita Baiden, Diadier Diallo, Peter G Smith and Fred N Binka
    Citation: Malaria Journal 2010 9:103
    Content type: Case study Published on:

  27. In Uganda, long-lasting insecticidal nets (LLIN) have been predominantly delivered through two public sector channels: targeted campaigns or routine antenatal care (ANC) services. Their combination in a mixed-...

    Authors: Jan H Kolaczinski, Kate Kolaczinski, Daniel Kyabayinze, Daniel Strachan, Matilda Temperley, Nayantara Wijayanandana and Albert Kilian
    Citation: Malaria Journal 2010 9:102
    Content type: Research Published on:

  28. Various factors impact the severity of malaria, including the nutritional status of the host. Vitamin E, an intra and extracellular anti-oxidant, is one such nutrient whose absence was shown previously to nega...

    Authors: Maria S Herbas, Yoshiko Y Ueta, Chie Ichikawa, Mayumi Chiba, Kana Ishibashi, Mototada Shichiri, Shinya Fukumoto, Naoaki Yokoyama, Motohiro Takeya, Xuenan Xuan, Hiroyuki Arai and Hiroshi Suzuki
    Citation: Malaria Journal 2010 9:101
    Content type: Research Published on:

  29. Infected humans make protective antibody responses to the PfEMP1 adhesion antigens exported by Plasmodium falciparum parasites to the erythrocyte membrane, but little is known about the kinetics of this antibody-...

    Authors: Lars M Joergensen, Ali Salanti, Tina Dobrilovic, Lea Barfod, Tue Hassenkam, Thor G Theander, Lars Hviid and David E Arnot
    Citation: Malaria Journal 2010 9:100
    Content type: Research Published on:

  31. School children have been increasingly recognized as health messengers for malaria control. However, little evidence is available. The objective of this study was to determine the impact of school-based malari...

    Authors: Irene Ayi, Daisuke Nonaka, Josiah K Adjovu, Shigeki Hanafusa, Masamine Jimba, Kwabena M Bosompem, Tetsuya Mizoue, Tsutomu Takeuchi, Daniel A Boakye and Jun Kobayashi
    Citation: Malaria Journal 2010 9:98
    Content type: Research Published on:

  32. Both artemether and artesunate have been shown to be superior to quinine for the treatment of severe falciparum malaria in Southeast Asian adults, although the magnitude of the superiority has been greater for...

    Authors: Nguyen H Phu, Phung Q Tuan, Nicholas Day, Nguyen TH Mai, Tran TH Chau, Ly V Chuong, Dinh X Sinh, Nicholas J White, Jeremy Farrar and Tran T Hien
    Citation: Malaria Journal 2010 9:97
    Content type: Research Published on:

  33. Effective malaria control depends on timely acquisition of information on new cases, their location and their frequency so as to deploy supplies, plan interventions or focus attention on specific locations app...

    Authors: Aniset Kamanga, Petros Moono, Gillian Stresman, Sungano Mharakurwa and Clive Shiff
    Citation: Malaria Journal 2010 9:96
    Content type: Methodology Published on:

  34. Rapid diagnostic tests (RDTs) for malaria are at the early stages of introduction across malaria endemic countries. This is central to efforts to decrease malaria overdiagnosis and the consequent overuse of va...

    Authors: Clare IR Chandler, Christopher JM Whitty and Evelyn K Ansah
    Citation: Malaria Journal 2010 9:95
    Content type: Research Published on:

  35. Apical membrane antigen 1 (AMA-1) and merozoite surface protein 1 (MSP1) of Plasmodium falciparum are two leading blood-stage malaria vaccine candidates. A P. falciparum chimeric protein 2.9 (PfCP-2.9) has been c...

    Authors: Changling Li, Rui Wang, Yuan Wu, Dongmei Zhang, Zhicheng He and Weiqing Pan
    Citation: Malaria Journal 2010 9:94
    Content type: Research Published on:

  36. In the 1990s, the experience of eliminating malaria from Aneityum Island, Vanuatu is often given as evidence for the potential to eliminate malaria in the south-west Pacific. This experience, however, cannot p...

    Authors: Jo-An M Atkinson, Lisa Fitzgerald, Hilson Toaliu, George Taleo, Anna Tynan, Maxine Whittaker, Ian Riley and Andrew Vallely
    Citation: Malaria Journal 2010 9:93
    Content type: Research Published on:

  38. Agricultural practices such as the use of irrigation during rice cultivation, the use of ponds for fish farming and the storage of water in tanks for livestock provide suitable breeding grounds for anthropophy...

    Authors: Oladimeji Oladepo, Grace O Tona, Frederick O Oshiname and Musibau A Titiloye
    Citation: Malaria Journal 2010 9:91
    Content type: Research Published on:

  39. Nucleosome assembly proteins (NAPs) are histone chaperones that are crucial for the shuttling and incorporation of histones into nucleosomes. NAPs participate in the assembly and disassembly of nucleosomes thu...

    Authors: Jasmita Gill, Anuj Kumar, Manickam Yogavel, Hassan Belrhali, SK Jain, Melanie Rug, Monica Brown, Alexander G Maier and Amit Sharma
    Citation: Malaria Journal 2010 9:90
    Content type: Research Published on:

  40. Chloroquine-resistant Plasmodium falciparum was first described in the Republic of Vanuatu in the early 1980s. In 1991, the Vanuatu Ministry of Health instituted new treatment guidelines for uncomplicated P. falc...

    Authors: Michael H Kinzer, Krisin Chand, Hasan Basri, Edith R Lederman, Augustina I Susanti, Iqbal Elyazar, George Taleo, William O Rogers, Michael J Bangs and Jason D Maguire
    Citation: Malaria Journal 2010 9:89
    Content type: Research Published on:

  41. Early diagnosis and treatment of malaria are necessary components in the control of malaria. The gold standard light microscopy technique has high sensitivity, but is a relatively time-consuming procedure espe...

    Authors: Saad El-Din H Hassan, Somia I Okoued, Mahmoud A Mudathir and Elfatih M Malik
    Citation: Malaria Journal 2010 9:88
    Content type: Research Published on:

  42. Malarial anaemia is characterized by destruction of malaria infected red blood cells and suppression of erythropoiesis. Interleukin 12 (IL12) significantly boosts erythropoietic responses in murine models of m...

    Authors: Lyna Zhang, Donald Prather, Jodi Vanden Eng, Sara Crawford, Simon Kariuki, Feiko ter Kuile, Dianne Terlouw, Bernard Nahlen, Altaf A Lal, Laurence Slutsker, Venkatachalam Udhayakumar and Ya Ping Shi
    Citation: Malaria Journal 2010 9:87
    Content type: Research Published on:

  43. In the advent of increasing international collaborative research involving participants drawn from populations with diverse cultural backgrounds, community engagement becomes very critical for the smooth condu...

    Authors: Aceme Nyika, Roma Chilengi, Deus Ishengoma, Sally Mtenga, Mahamadou A Thera, Mahamadou S Sissoko, John Lusingu, Alfred B Tiono, Ogobara Doumbo, Sodiomon B Sirima, Martha Lemnge and Wen L Kilama
    Citation: Malaria Journal 2010 9:86
    Content type: Case study Published on:

  44. Plasmodium berghei ANKA infection in C57Bl/6 mice induces cerebral malaria (CM), which reproduces, to a large extent, the pathological features of human CM. However, experimental CM incidence is variable (50-100%...

    Authors: Yuri C Martins, Guilherme L Werneck, Leonardo J Carvalho, Beatriz PT Silva, Bruno G Andrade, Tadeu M Souza, Diogo O Souza and Cláudio T Daniel-Ribeiro
    Citation: Malaria Journal 2010 9:85
    Content type: Methodology Published on:

  46. The emergence of pyrethroid resistance in Anopheles gambiae has become a serious concern to the future success of malaria control. In Benin, the National Malaria Control Programme has recently planned to scaling ...

    Authors: Anges W Yadouleton, Gil Padonou, Alex Asidi, Nicolas Moiroux, Sahabi Bio-Banganna, Vincent Corbel, Raphael N'guessan, Dina Gbenou, Imorou Yacoubou, Kinde Gazard and Martin C Akogbeto
    Citation: Malaria Journal 2010 9:83
    Content type: Research Published on:

  47. Phase III trials of the malaria vaccine, RTS, S, are now underway across multiple sites of varying transmission intensity in Africa. Heterogeneity in exposure, vaccine response and waning of efficacy may bias ...

    Authors: Michael T White, Jamie T Griffin, Chris J Drakeley and Azra C Ghani
    Citation: Malaria Journal 2010 9:82
    Content type: Research Published on:

  48. The mechanisms by which malaria up and down-regulates CYP activities are not understood yet. It is also unclear whether CYP activities are modulated during non-lethal malaria infections. This study was underta...

    Authors: Ana Cecilia AX De-Oliveira, Renato S Carvalho, Flavio HM Paixão, Hellen S Tavares, Luciana S Gueiros, Carolina M Siqueira and Francisco JR Paumgartten
    Citation: Malaria Journal 2010 9:81
    Content type: Research Published on:

  49. With an Annual Parasite Incidence (API) of 132.1, in the high and moderate risks zones, the Maroni area of French Guiana has the second highest malaria incidence of South-America after Guyana (API = 183.54) an...

    Authors: Florence Fouque, Pascal Gaborit, Romuald Carinci, Jean Issaly and Romain Girod
    Citation: Malaria Journal 2010 9:80
    Content type: Research Published on:
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Malaria Journal

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