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  1. Plasmodium falciparum genotyping with molecular polymorphic markers is widely employed to distinguish recrudescence from re-infection in antimalarial drug efficacy monitoring programmes. However, limitations occu...

    Authors: Petrica Rouse, Mtawa AP Mkulama, Philip E Thuma and Sungano Mharakurwa

    Citation: Malaria Journal 2008 7:185

    Content type: Research

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  2. The sequencing of genomes of the Plasmodium species causing malaria, offers immense opportunities to aid in the development of new therapeutics and vaccine candidates through Bioinformatics tools and resources.

    Authors: Rupanjali Chaudhuri, Shakil Ahmed, Faraz Alam Ansari, Harinder Vir Singh and Srinivasan Ramachandran

    Citation: Malaria Journal 2008 7:184

    Content type: Commentary

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  3. The geographic and temporal distribution of M and S molecular forms of the major Afrotropical malaria vector species Anopheles gambiae s.s. at the western extreme of their range of distribution has never been inv...

    Authors: Beniamino Caputo, Davis Nwakanma, Musa Jawara, Majidah Adiamoh, Ibrahima Dia, Lassana Konate, Vincenzo Petrarca, David J Conway and Alessandra della Torre

    Citation: Malaria Journal 2008 7:182

    Content type: Research

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  4. Case-management with artemether-lumefantrine (AL) is one of the key strategies to control malaria in many African countries. Yet, the reports on translation of AL implementation activities into clinical practi...

    Authors: Dejan Zurovac, James K Tibenderana, Joan Nankabirwa, James Ssekitooleko, Julius N Njogu, John B Rwakimari, Sylvia Meek, Ambrose Talisuna and Robert W Snow

    Citation: Malaria Journal 2008 7:181

    Content type: Research

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  5. Intermittent preventive treatment with sulphadoxine-pyrimethamine for pregnant women (IPTp-SP) is currently being scaled up in many countries in sub-Saharan Africa. Despite high antenatal clinic (ANC) attendan...

    Authors: Sabine Gies, Sheick Oumar Coulibaly, Florence Tiemegna Ouattara, Clotilde Ky, Bernard John Brabin and Umberto D'Alessandro

    Citation: Malaria Journal 2008 7:180

    Content type: Research

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  6. Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries. However, irreversible ototoxicity associ...

    Authors: Robert Gürkov, Teferi Eshetu, Isabel Barreto Miranda, Nicole Berens-Riha, Yoseph Mamo, Tsinuel Girma, Eike Krause, Michael Schmidt, John-Martin Hempel and Thomas Löscher

    Citation: Malaria Journal 2008 7:179

    Content type: Research

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  7. According to entomological studies conducted over the past 30 years, there was low malaria transmission in suburb of Dakar but little evidence of it in the downtown area. However; there was some evidence of lo...

    Authors: Frederic Pagès, Gaetan Texier, Bruno Pradines, Libasse Gadiaga, Vanessa Machault, Fanny Jarjaval, Kristell Penhoat, Franck Berger, Jean-François Trape, Christophe Rogier and Cheikh Sokhna

    Citation: Malaria Journal 2008 7:178

    Content type: Research

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  8. Detection of the four malaria-causing Plasmodium species (Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale and Plasmodium malariae) within their mosquito hosts is an essential component of vector control...

    Authors: Chris Bass, Dimitra Nikou, Andrew M Blagborough, John Vontas, Robert E Sinden, Martin S Williamson and Linda M Field

    Citation: Malaria Journal 2008 7:177

    Content type: Methodology

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  9. Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having malaria parasites becomes paramou...

    Authors: Charlotte M Zikusooka, Diane McIntyre and Karen I Barnes

    Citation: Malaria Journal 2008 7:176

    Content type: Research

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  10. The Ig Fc receptor family is an important link between the humoral and cellular immune systems. The association of a dimorphism in amino acid 131 (R/H) of the FcγRIIa with malaria severity, the R-allele being ...

    Authors: Elisabeth Israelsson, Manijeh Vafa, Bakary Maiga, Anna Lysén, Nnaemeka C Iriemenam, Amagana Dolo, Ogobara K Doumbo, Marita Troye-Blomberg and Klavs Berzins

    Citation: Malaria Journal 2008 7:175

    Content type: Research

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  11. Plasmodium vivax is estimated to affect 75 million people annually. It is reportedly absent, however, from west and central Africa due to the high prevalence of the Duffy negative phenotype in the indigenous popu...

    Authors: Richard L Culleton, Toshihiro Mita, Mathieu Ndounga, Holger Unger, Pedro VL Cravo, Giacomo M Paganotti, Nobuyuki Takahashi, Akira Kaneko, Hideaki Eto, Halidou Tinto, Corine Karema, Umberto D'Alessandro, Virgilio do Rosário, Takatoshi Kobayakawa, Francine Ntoumi, Richard Carter…

    Citation: Malaria Journal 2008 7:174

    Content type: Research

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  12. In high-transmission areas, developing immunity to symptomatic Plasmodium falciparum infections requires 2–10 years of uninterrupted exposure. Delayed malaria-immunity has been attributed to difficult-to-develop ...

    Authors: Katherine J Torres, Eva H Clark, Jean N Hernandez, Katherine E Soto-Cornejo, Dionicia Gamboa and OraLee H Branch

    Citation: Malaria Journal 2008 7:173

    Content type: Research

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  13. The combination of artesunate and mefloquine has been reported to be effective against multi-drug resistant Plasmodium falciparum malaria, which has been reported in Nigeria. The objective of this multi-centre st...

    Authors: Philip U Agomo, Martin M Meremikwu, Ismaila M Watila, Innocent J Omalu, Friday A Odey, Stephen Oguche, Valentine I Ezeiru and Olugbenga O Aina

    Citation: Malaria Journal 2008 7:172

    Content type: Research

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  14. Pregnancy-associated malaria (PAM) is a serious consequence of Plasmodium falciparum-infected erythrocytes sequestration in the placenta through the adhesion to the placental receptor chondroitin sulfate A (CSA)....

    Authors: Pablo Fernandez, Nicola K Viebig, Sébastien Dechavanne, Catherine Lépolard, Jürg Gysin, Artur Scherf and Benoit Gamain

    Citation: Malaria Journal 2008 7:170

    Content type: Research

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  15. Amodiaquine is frequently used as a partner drug in combination therapy or in some setting as monotherapy, but little is known about its effects on gametocyte production and sex ratio and its potential influen...

    Authors: Akintunde Sowunmi, Sulayman T Balogun, Grace O Gbotosho and Christian T Happi

    Citation: Malaria Journal 2008 7:169

    Content type: Research

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  16. The current status of insecticide resistance and the underlying resistance mechanisms were studied in the major vector of malaria, Anopheles culicifacies, and the secondary vector, Anopheles subpictus in five dis...

    Authors: M Devika B Perera, Janet Hemingway and SHP Parakrama Karunaratne

    Citation: Malaria Journal 2008 7:168

    Content type: Research

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  17. Malaria control is currently receiving significant international commitment. As part of this commitment, Rwanda has undertaken a two-pronged approach to combating malaria via mass distribution of long-lasting ...

    Authors: Amy C Sievers, Jenifer Lewey, Placide Musafiri, Molly F Franke, Blaise J Bucyibaruta, Sara N Stulac, Michael L Rich, Corine Karema and Johanna P Daily

    Citation: Malaria Journal 2008 7:167

    Content type: Research

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  18. Each year, several thousand cases of malaria occur in south-central Vietnam. Evidence from elsewhere suggests that malaria can have an economic impact on the household as the illness prevents households from c...

    Authors: Chantal M Morel, Ngo Duc Thang, Nguyen Xuan Xa, Le Xuan Hung, Le Khan Thuan, Pham Van Ky, Annette Erhart, Anne J Mills and Umberto D'Alessandro

    Citation: Malaria Journal 2008 7:166

    Content type: Research

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  19. To combat malaria, the Kenya Ministry of Health and nongovernmental organizations (NGOs) have distributed insecticide-treated nets (ITNs) for use over beds, with coverage for children under five years of age i...

    Authors: Noboru Minakawa, Gabriel O Dida, Gorge O Sonye, Kyoko Futami and Satoshi Kaneko

    Citation: Malaria Journal 2008 7:165

    Content type: Research

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  20. The Zambian Malaria Control Programme with the Roll Back Malaria (RBM) partners have developed the current National Malaria Strategic Plan (NMSP 2006–2011) which focuses on prevention based on the Integrated V...

    Authors: Emmanuel Chanda, Fred Masaninga, Michael Coleman, Chadwick Sikaala, Cecilia Katebe, Michael MacDonald, Kumar S Baboo, John Govere and Lucien Manga

    Citation: Malaria Journal 2008 7:164

    Content type: Case study

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  21. SINEs (Short INterspersed Elements) are homoplasy-free and co-dominant genetic markers which are considered to represent useful tools for population genetic studies, and could help clarifying the speciation pr...

    Authors: Federica Santolamazza, Emiliano Mancini, Frédéric Simard, Yumin Qi, Zhijian Tu and Alessandra della Torre

    Citation: Malaria Journal 2008 7:163

    Content type: Research

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  22. Malaria is endemic in the low-altitude areas of the northern and eastern parts of South Africa with seasonal transmission. The aim of this descriptive study is to give an overview of the malaria incidence and ...

    Authors: Annette AM Gerritsen, Philip Kruger, Maarten F Schim van der Loeff and Martin P Grobusch

    Citation: Malaria Journal 2008 7:162

    Content type: Research

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  23. Introduction of artemisinin combination therapy (ACT) has boosted interest in parasite-based malaria diagnosis, leading to increased use of rapid diagnostic tests (RDTs), particularly in rural settings where m...

    Authors: Steven A Harvey, Larissa Jennings, Masela Chinyama, Fred Masaninga, Kurt Mulholland and David R Bell

    Citation: Malaria Journal 2008 7:160

    Content type: Research

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  24. Maps of malaria distribution are vital for optimal allocation of resources for anti-malarial activities. There is a lack of reliable contemporary malaria maps in endemic countries in sub-Saharan Africa. This p...

    Authors: Abdisalan M Noor, Archie CA Clements, Peter W Gething, Grainne Moloney, Mohammed Borle, Tanya Shewchuk, Simon I Hay and Robert W Snow

    Citation: Malaria Journal 2008 7:159

    Content type: Research

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  25. Medical entomologists increasingly recognize that the ability to make inferences between laboratory experiments of vector biology and epidemiological trends observed in the field is hindered by a conceptual an...

    Authors: Heather M Ferguson, Kija R Ng'habi, Thomas Walder, Demetrius Kadungula, Sarah J Moore, Issa Lyimo, Tanya L Russell, Honorathy Urassa, Hassan Mshinda, Gerry F Killeen and Bart GJ Knols

    Citation: Malaria Journal 2008 7:158

    Content type: Methodology

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  26. It has been shown previously that human monocytes fed with haemozoin (HZ) or trophozoite-parasitized RBCs displayed increased matrix metalloproteinase-9 (MMP-9) enzyme activity and protein/mRNA expression and ...

    Authors: Mauro Prato, Valentina Gallo, Giuliana Giribaldi and Paolo Arese

    Citation: Malaria Journal 2008 7:157

    Content type: Research

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  27. Malaria in The Gambia is highly seasonal, with transmission occurring as Anopheles gambiae s.l. populations expand during and immediately after a single annual rainy season that lasts from June to October. There ...

    Authors: Musa Jawara, Margaret Pinder, Chris J Drakeley, Davis C Nwakanma, Ebrima Jallow, Claus Bogh, Steve W Lindsay and David J Conway

    Citation: Malaria Journal 2008 7:156

    Content type: Research

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  28. Antibodies targeting variant antigens expressed on the surface of Plasmodium falciparum infected erythrocytes have been associated with protection from clinical malaria. The precise target for these antibodies is...

    Authors: Claire L Mackintosh, Zoe Christodoulou, Tabitha W Mwangi, Moses Kortok, Robert Pinches, Thomas N Williams, Kevin Marsh and Christopher I Newbold

    Citation: Malaria Journal 2008 7:155

    Content type: Research

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  29. Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with implications for changes in treatment...

    Authors: Elizabeth A Ashley, Loretxu Pinoges, Eleanor Turyakira, Grant Dorsey, Francesco Checchi, Hasifa Bukirwa, Ingrid van den Broek, Issaka Zongo, Pedro Pablo Palma Urruta, Michel van Herp, Suna Balkan, Walter R Taylor, Piero Olliaro and Jean-Paul Guthmann

    Citation: Malaria Journal 2008 7:154

    Content type: Methodology

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  30. The use of plant repellents against nuisance biting insects is common and its potential for malaria vector control requires evaluation in areas with different level of malaria endemicity. The essential oils of Oc...

    Authors: Eliningaya J Kweka, Franklin Mosha, Asanterabi Lowassa, Aneth M Mahande, Jovin Kitau, Johnson Matowo, Michael J Mahande, Charles P Massenga, Filemoni Tenu, Emmanuel Feston, Ester E Lyatuu, Michael A Mboya, Rajabu Mndeme, Grace Chuwa and Emmanuel A Temu

    Citation: Malaria Journal 2008 7:152

    Content type: Research

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  31. To investigate the impact of urban agriculture on malaria transmission risk in urban Accra larval and adult stage mosquito surveys, were performed. Local transmission was implicated as Anopheles spp. were found b...

    Authors: Eveline Klinkenberg, PJ McCall, Michael D Wilson, Felix P Amerasinghe and Martin J Donnelly

    Citation: Malaria Journal 2008 7:151

    Content type: Research

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  32. Malaria is a very important cause of anaemia in tropical countries. Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For comparisons across studies, it is often ne...

    Authors: Sue J Lee, Kasia Stepniewska, Nicholas Anstey, Elizabeth Ashley, Karen Barnes, Tran Quang Binh, Umberto D'Alessandro, Nicholas PJ Day, Peter J de Vries, Grant Dorsey, Jean-Paul Guthmann, Mayfong Mayxay, Paul Newton, Francois Nosten, Piero Olliaro, Lyda Osario…

    Citation: Malaria Journal 2008 7:149

    Content type: Methodology

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  33. Multidrug resistance has emerged to both Plasmodium vivax and Plasmodium falciparum and yet the comparative epidemiology of these infections is poorly defined.

    Authors: Muhammad Karyana, Lenny Burdarm, Shunmay Yeung, Enny Kenangalem, Noah Wariker, Rilia Maristela, Ketut Gde Umana, Ram Vemuri, Maurits J Okoseray, Pasi M Penttinen, Peter Ebsworth, Paulus Sugiarto, Nicholas M Anstey, Emiliana Tjitra and Richard N Price

    Citation: Malaria Journal 2008 7:148

    Content type: Research

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  34. The Camargue region is a former malaria endemic area, where potential Anopheles vectors are still abundant. Considering the importation of Plasmodium due to the high number of imported malaria cases in France, th...

    Authors: Nicolas Ponçon, Annelise Tran, Céline Toty, Adrian JF Luty and Didier Fontenille

    Citation: Malaria Journal 2008 7:147

    Content type: Research

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  35. Malaria transmission in most agricultural ecosystems is complex and hence the need for developing a holistic malaria control strategy with adequate consideration of socio-economic factors driving transmission ...

    Authors: Peter N Ng'ang'a, Josephat Shililu, Gayathri Jayasinghe, Violet Kimani, Charity Kabutha, Lucy Kabuage, Ephantus Kabiru, John Githure and Clifford Mutero

    Citation: Malaria Journal 2008 7:146

    Content type: Research

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  36. The Abuja target of increasing the proportion of people sleeping under insecticide-treated nets (ITNs) to 60% by the year 2005, as one of the measures for malaria control in Africa, has generated an influx of ...

    Authors: Olusola B Oresanya, Moshe Hoshen and Olayemi T Sofola

    Citation: Malaria Journal 2008 7:145

    Content type: Research

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  37. The Plasmodium falciparum P126 protein is an asexual blood-stage malaria vaccine candidate antigen. Antibodies against P126 are able to inhibit parasite growth in vitro, and a major parasite-inhibitory epitope ha...

    Authors: Lilian Rose Pratt-Riccio, Selma Sallenave-Sales, Joseli de Oliveira-Ferreira, Bruno T da Silva, Monick Lindenmeyer Guimarães, Fátima Santos, Thatiane S de Simone, Mariza G Morgado, Salvatore G de Simone, Maria de Fátima Ferreira-Da-Cruz, Cláudio T Daniel-Ribeiro, Mariano G Zalis, Daniel Camus and Dalma M Banic

    Citation: Malaria Journal 2008 7:144

    Content type: Research

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  38. Early diagnosis and prompt treatment including appropriate home-based treatment of malaria is a major strategy for malaria control. A major determinant of clinical outcome in case management is compliance and ...

    Authors: Adebola E Orimadegun, Olukemi K Amodu, Peter E Olumese and Olayemi O Omotade

    Citation: Malaria Journal 2008 7:143

    Content type: Research

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  39. Antigen-specific antibody-mediated immune responses play an important role in natural protection against clinical malaria, but conflicting estimates of this association have emerged from immuno-epidemiological...

    Authors: Daniel Dodoo, Anastasia Aikins, Kwadwo Asamoah Kusi, Helena Lamptey, Ed Remarque, Paul Milligan, Samuel Bosomprah, Roma Chilengi, Yaa Difie Osei, Bartholomew Dicky Akanmori and Michael Theisen

    Citation: Malaria Journal 2008 7:142

    Content type: Research

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  40. The length of the gonotrophic cycle varies the vectorial capacity of a mosquito vector and therefore its exact estimation is important in epidemiological modelling. Because the gonotrophic cycle length depends...

    Authors: Frédéric J Lardeux, Rosenka H Tejerina, Vicente Quispe and Tamara K Chavez

    Citation: Malaria Journal 2008 7:141

    Content type: Research

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  41. El Niño events were suggested as a potential predictor for malaria epidemics in Sri Lanka based on the coincidence of nine out of 16 epidemics with El Niño events from 1870 to 1945. Here the potential for the ...

    Authors: Lareef Zubair, Gawrie N Galappaththy, Hyemin Yang, Janaki Chandimala, Zeenas Yahiya, Priyanie Amerasinghe, Neil Ward and Stephen J Connor

    Citation: Malaria Journal 2008 7:140

    Content type: Research

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  42. In order to harmonize results for the detection and quantification of Plasmodium falciparum DNA by nucleic acid amplification technique (NAT)-based assays, a World Health Organization (WHO) collaborative study wa...

    Authors: David J Padley, Alan B Heath, Colin Sutherland, Peter L Chiodini and Sally A Baylis

    Citation: Malaria Journal 2008 7:139

    Content type: Research

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  43. Larval control of malaria vectors has been historically successful in reducing malaria transmission, but largely fell out of favour with the introduction of synthetic insecticides and bed nets. However, an int...

    Authors: Rebecca L Gianotti, Arne Bomblies, Mustafa Dafalla, Ibrahim Issa-Arzika, Jean-Bernard Duchemin and Elfatih AB Eltahir

    Citation: Malaria Journal 2008 7:138

    Content type: Research

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  44. Plasmodium falciparum STEVOR proteins, encoded by the multicopy stevor gene family have no known biological functions. Their expression and unique locations in different parasite life cycle stages evoke multiple ...

    Authors: Ayman Khattab, Insa Bonow, Nadine Schreiber, Michaela Petter, Christel Schmetz and Mo-Quen Klinkert

    Citation: Malaria Journal 2008 7:137

    Content type: Research

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  45. The adaptation of Anopheles gambiae to humans and its environment involves an ongoing speciation process that can be best demonstrated by the existence of various chromosomal forms adapted to different environmen...

    Authors: Mamadou Ousmane Ndiath, Cécile Brengues, Lassana Konate, Cheikh Sokhna, Christian Boudin, Jean François Trape and Didier Fontenille

    Citation: Malaria Journal 2008 7:136

    Content type: Research

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