Guerra CA, Gikandi PW, Tatem AJ, Noor AM, Smith DL, Hay SI, Snow RW: The limits and intensity of Plasmodium falciparum transmission: implications for malaria control and elimination worldwide. PLoS Med. 2008, 5: e38-10.1371/journal.pmed.0050038.
Article
PubMed Central
PubMed
Google Scholar
Baird JK: Neglect of Plasmodium vivax malaria. Trends Parasitol. 2007, 23: 533-539.
Article
PubMed
Google Scholar
Barnes KI, Durrheim DN, Little F, Jackson A, Mehta U, Allen E, Dlamini SS, Tsoka J, Bredenkamp B, Mthembu DJ, White NJ, Sharp BL: Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa. PLoS Med. 2005, 2: e330-10.1371/journal.pmed.0020330.
Article
PubMed Central
PubMed
Google Scholar
Bhattarai A, Ali AS, Kachur SP, Martensson A, Abbas AK, Khatib R, Al-Mafazy AW, Ramsan M, Rotllant G, Gerstenmaier JF, Molteni F, Abdulla S, Montgomery SM, Kaneko A, Björkman A: Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar. PLoS Med. 2007, 4: e309-10.1371/journal.pmed.0040309.
Article
PubMed Central
PubMed
Google Scholar
Nyarango PM, Gebremeskel T, Mebrahtu G, Mufunda J, Abdulmumini U, Ogbamariam A, Kosia A, Gebremichael A, Gunawardena D, Ghebrat Y, Okbaldet Y: A steep decline of malaria morbidity and mortality trends in Eritrea between 2000 and 2004: the effect of combination of control methods. Malar J. 2006, 5: 33-10.1186/1475-2875-5-33.
Article
PubMed Central
PubMed
Google Scholar
Ceesay SJ, Casals-Pascual C, Erskine J, Anya SE, Duah NO, Fulford AJ, Sesay SS, Abubakar I, Dunyo S, Sey O, Palmer A, Fofana M, Corrah T, Bojang KA, Whittle HC, Greenwood BM, Conway DJ: Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis. Lancet. 2008, 372: 1545-1554. 10.1016/S0140-6736(08)61654-2.
Article
PubMed Central
PubMed
Google Scholar
Okiro EA, Hay SI, Gikandi PW, Sharif SK, Noor AM, Peshu N, Marsh K, Snow RW: The decline in paediatric malaria admissions on the coast of Kenya. Malar J. 2007, 6: 151-10.1186/1475-2875-6-151.
Article
PubMed Central
PubMed
Google Scholar
O'Meara WP, Bejon P, Mwangi TW, Okiro EA, Peshu N, Snow RW, Newton CR, Marsh K: Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya. Lancet. 2008, 372: 1555-1562. 10.1016/S0140-6736(08)61655-4.
Article
PubMed Central
PubMed
Google Scholar
Greenwood BM: From malaria control to elimination: implications for the research agenda. Trends Parasitol. 2008, 24: 449-454. 10.1016/j.pt.2008.07.002.
Article
PubMed
Google Scholar
Feachem R, Sabot O: A new global malaria eradication strategy. Lancet. 2008, 371: 1633-1635. 10.1016/S0140-6736(08)60424-9.
Article
PubMed
Google Scholar
Kaneko A, Taleo G, Kalkoa M, Yamar S, Kobayakawa T, Bjorkman A: Malaria eradication on islands. Lancet. 2000, 356: 1560-1564. 10.1016/S0140-6736(00)03127-5.
Article
CAS
PubMed
Google Scholar
Drakeley C, Sutherland C, Bousema JT, Sauerwein RW, Targett GA: The epidemiology of Plasmodium falciparum gametocytes: weapons of mass dispersion. Trends Parasitol. 2006, 22: 424-430. 10.1016/j.pt.2006.07.001.
Article
PubMed
Google Scholar
Abdel-Wahab A, Abdel-Muhsin AM, Ali E, Suleiman S, Ahmed S, Walliker D, Babiker HA: Dynamics of gametocytes among Plasmodium falciparum clones in natural infections in an area of highly seasonal transmission. J Infect Dis. 2002, 185: 1838-1842. 10.1086/340638.
Article
PubMed
Google Scholar
Drakeley CJ, Akim NI, Sauerwein RW, Greenwood BM, Targett GA: Estimates of the infectious reservoir of Plasmodium falciparum malaria in The Gambia and in Tanzania. Trans R Soc Trop Med Hyg. 2000, 94: 472-476. 10.1016/S0035-9203(00)90056-7.
Article
CAS
PubMed
Google Scholar
Schneider P, Bousema JT, Gouagna LC, Otieno S, Vegte-Bolmer van de M, Omar SA, Sauerwein RW: Submicroscopic Plasmodium falciparum gametocyte densities frequently result in mosquito infection. Am J Trop Med Hyg. 2007, 76: 470-474.
PubMed
Google Scholar
Bousema JT, Schneider P, Gouagna LC, Drakeley CJ, Tostmann A, Houben R, Githure JI, Ord R, Sutherland CJ, Omar SA, Sauerwein RW: Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum. J Infect Dis. 2006, 193: 1151-1159. 10.1086/503051.
Article
CAS
PubMed
Google Scholar
Shekalaghe SA, Bousema JT, Kunei KK, Lushino P, Masokoto A, Wolters LR, Mwakalinga S, Mosha FW, Sauerwein RW, Drakeley CJ: Submicroscopic Plasmodium falciparum gametocyte carriage is common in an area of low and seasonal transmission in Tanzania. Trop Med Int Health. 2007, 12: 547-553.
Article
PubMed
Google Scholar
Woolhouse ME, Dye C, Etard JF, Smith T, Charlwood JD, Garnett GP, Hagan P, Hii JL, Ndhlovu PD, Quinnell RJ: Heterogeneities in the transmission of infectious agents: implications for the design of control programs. Proc Natl Acad Sci USA. 1997, 94: 338-342. 10.1073/pnas.94.1.338.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kasehagen LJ, Mueller I, McNamara DT, Bockarie MJ, Kiniboro B, Rare L, Lorry K, Kastens W, Reeder JC, Kazura JW, Zimmerman PA: Changing patterns of Plasmodium blood-stage infections in the Wosera region of Papua New Guinea monitored by light microscopy and high throughput PCR diagnosis. Am J Trop Med Hyg. 2006, 75: 588-596.
PubMed Central
PubMed
Google Scholar
Malaria Vaccine Technology Roadmap. [http://www.malariavaccineroadmap.net]
Stevenson MM, Zavala F: Immunology of malaria infections – implications for the design and development of malaria vaccines. Parasite Immunol. 2006, 28: 1-60. 10.1111/j.1365-3024.2006.00797.x.
Article
CAS
PubMed
Google Scholar
Targett GA: Malaria vaccines 1985–2005: a full circle?. Trends Parasitol. 2005, 21: 499-503. 10.1016/j.pt.2005.08.018.
Article
CAS
PubMed
Google Scholar
Sanaria. [http://www.sanaria.com]
Mueller AK, Labaied M, Kappe SH, Matuschewski K: Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature. 2005, 433: 164-167. 10.1038/nature03188.
Article
CAS
PubMed
Google Scholar
Labaied M, Harupa A, Dumpit RF, Coppens I, Mikolajczak SA, Kappe SH: Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infect Immun. 2007, 75: 3758-3768. 10.1128/IAI.00225-07.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jobe O, Lumsden J, Mueller AK, Williams J, Silva-Rivera H, Kappe SH, Schwenk RJ, Matuschewski K, Krzych U: Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. J Infect Dis. 2007, 196: 599-607. 10.1086/519743.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mueller AK, Deckert M, Heiss K, Goetz K, Matuschewski K, Schluter D: Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells. Am J Pathol. 2007, 171: 107-115. 10.2353/ajpath.2007.060792.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tarun AS, Dumpit RF, Camargo N, Labaied M, Liu P, Takagi A, Wang R, Kappe SH: Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. J Infect Dis. 2007, 196: 608-616. 10.1086/519742.
Article
CAS
PubMed
Google Scholar
Barbosa A, Naniche D, Manaca MN, Aponte JJ, Mandomando I, Aide P, Renom M, Sacarlal J, Ballou WR, Moris P, Cohen J, Dubovsky F, Millman J, Alonso PL: Assessment of cellular immune responses in infants participating in a RTS, S/ASO2D phase I/IIB trial in Mozambique. Am J Trop Med Hyg. 2007, 77 (Abstr 9): 2-3.
Google Scholar
Lell B, Agnandji S, von Glasenapp I, Oyakhiromen S, Haertle S, Kremsner PG, Ramboer I, Lievens M, Ballou WR, Vekemans J, Dubois M-C, Demoitie M-A, Cohen J, Villafana T, Carter T, Petersen T: A randomized, observer-blind trial to compare safety and immunogenicity of two adjuvanted RTS, S anti-malaria vaccine candidates in Gabonese children. Am J Trop Med Hyg. 2007, 77 (Abstr 10): 3-
Google Scholar
Anyona SB, Hunja CW, Kifude CM, Polhemus ME, Heppner DG, Leach A, Lievens M, Ballou WR, Cohen J, Sutherland C: Impact of RTS, S/ASO2A and RTS, s/ASO1B on multiplicity of infections and CSP T-cell epitopes of Plasmodium falciparum in adults participating in a malaria vaccine clinical trial. Am J Trop Med Hyg. 2007, 77 (Abstr 578): 166-
Google Scholar
Kester KE, McKinney DA, Tornieporth N, Ockenhouse CF, Heppner DG, Hall T, Krzych U, Delchambre M, Voss G, Dowler MG, Palensky J, Wittes J, Cohen J, Ballou WR, RTS S Malaria Vaccine Evaluation Group: Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria. J Infect Dis. 2001, 183: 640-647. 10.1086/318534.
Article
CAS
PubMed
Google Scholar
Bojang KA, Milligan PJ, Pinder M, Vigneron L, Alloueche A, Kester KE, Ballou WR, Conway DJ, Reece WH, Gothard P, Yamuah L, Delchambre M, Voss G, Greenwood BM, Hill A, McAdam KP, Tornieporth N, Cohen JD, Doherty T, RTS S Malaria Vaccine Trial Team: Efficacy of RTS, S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial. Lancet. 2001, 358: 1927-1934. 10.1016/S0140-6736(01)06957-4.
Article
CAS
PubMed
Google Scholar
Alonso PL, Sacarlal J, Aponte JJ, Leach A, Macete E, Aide P, Sigauque B, Milman J, Mandomando I, Bassat Q, Guinovart C, Espasa M, Corachan S, Lievens M, Navia MM, Dubois MC, Menendez C, Dubovsky F, Cohen J, Thompson R, Ballou WR: Duration of protection with RTS, S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial. Lancet. 2005, 366: 2012-2018. 10.1016/S0140-6736(05)67669-6.
Article
CAS
PubMed
Google Scholar
Aponte JJ, Aide P, Renom M, Mandomando I, Bassat Q, Sacarlal J, Manaca MN, Lafuente S, Barbosa A, Leach A, Lievens M, Vekemans J, Sigauque B, Dubois MC, Demoitié MA, Sillman M, Savarese B, McNeil JG, Macete E, Ballou WR, Cohen J, Alonso PL: Safety of the RTS, S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial. Lancet. 2007, 370: 1543-1551. 10.1016/S0140-6736(07)61542-6.
Article
CAS
PubMed
Google Scholar
Hill AV: Pre-erythrocytic malaria vaccines: towards greater efficacy. Nat Rev Immunol. 2006, 6: 21-32. 10.1038/nri1746.
Article
CAS
PubMed
Google Scholar
Walther M: Advances in vaccine development against the pre-erythrocytic stage of Plasmodium falciparum malaria. Expert Rev Vaccines. 2006, 5: 81-93. 10.1586/14760584.5.1.81.
Article
CAS
PubMed
Google Scholar
Hu J, Chen Z, Gu J, Wan M, Shen Q, Kieny MP, He J, Li Z, Zhang Q, Reed ZH, Zhu Y, Li W, Cao Y, Qu L, Cao Z, Wang Q, Liu H, Pan X, Huang X, Zhang D, Xue X, Pan W: Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults. PLoS ONE. 2008, 3: e1952-10.1371/journal.pone.0001952.
Article
PubMed Central
PubMed
Google Scholar
Greenwood BM, Fidock DA, Kyle DE, Kappe SH, Alonso PL, Collins FH, Duffy PE: Malaria: progress, perils, and prospects for eradication. J Clin Invest. 2008, 118: 1266-1276. 10.1172/JCI33996.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dicko A, Sagara I, Ellis RD, Miura K, Guindo O, Kamate B, Sogoba M, Niambele MB, Sissoko M, Baby M, Dolo A, Mullen GE, Fay MP, Pierce M, Diallo DA, Saul A, Miller LH, Doumbo OK: Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children. PLoS ONE. 2008, 3: e1563-10.1371/journal.pone.0001563.
Article
PubMed Central
PubMed
Google Scholar
Malkin E, Long CA, Stowers AW, Zou L, Singh S, MacDonald NJ, Narum DL, Miles AP, Orcutt AC, Muratova O, Moretz SE, Zhou H, Diouf A, Fay M, Tierney E, Leese P, Mahanty S, Miller LH, Saul A, Martin LB: Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria. PLoS Clin Trials. 2007, 2: e12-10.1371/journal.pctr.0020012.
Article
PubMed Central
PubMed
Google Scholar
Richie T: High road, low road? Choices and challenges on the pathway to a malaria vaccine. Parasitology. 2006, 133 (Suppl S1): 13-144.
Google Scholar
Remarque EJ, Faber BW, Kocken CH, Thomas AW: Apical membrane antigen 1: a malaria vaccine candidate in review. Trends Parasitol. 2008, 24: 74-84. 10.1016/j.pt.2007.12.002.
Article
CAS
PubMed
Google Scholar
Druilhe P, Spertini F, Soesoe D, Corradin G, Mejia P, Singh S, Audran R, Bouzidi A, Oeuvray C, Roussilhon C: A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum. PLoS Med. 2005, 2: e344-10.1371/journal.pmed.0020344.
Article
PubMed Central
PubMed
Google Scholar
Genton B, Betuela I, Felger I, Al-Yaman F, Anders RF, Saul A, Rare L, Baisor M, Lorry K, Brown GV, Pye D, Irving DO, Smith TA, Beck HP, Alpers MP: A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1–2b trial in Papua New Guinea. J Infect Dis. 2002, 185: 820-827. 10.1086/339342.
Article
PubMed
Google Scholar
Baum J, Maier AG, Good RT, Simpson KM, Cowman AF: Invasion by P. falciparum merozoites suggests a hierarchy of molecular interactions. PLoS Pathog. 2005, 1: e37-10.1371/journal.ppat.0010037.
Article
PubMed Central
PubMed
Google Scholar
Takala SL, Coulibaly D, Thera MA, Dicko A, Smith DL, Guindo AB, Kone AK, Traore K, Ouattara A, Djimde AA, Sehdev PS, Lyke KE, Diallo DA, Doumbo OK, Plowe CV: Dynamics of polymorphism in a malaria vaccine antigen at a vaccine-testing site in Mali. PLoS Med. 2007, 4: e93-10.1371/journal.pmed.0040093.
Article
PubMed Central
PubMed
Google Scholar
Devi YS, Mukherjee P, Yazdani SS, Shakri AR, Mazumdar S, Pandey S, Chitnis CE, Chauhan VS: Immunogenicity of Plasmodium vivax combination subunit vaccine formulated with human compatible adjuvants in mice. Vaccine. 2007, 25: 5166-5174. 10.1016/j.vaccine.2007.04.080.
Article
CAS
PubMed
Google Scholar
Cavasini CE, Mattos LC, Couto AA, Bonini-Domingos CR, Valencia SH, Neiras WC, Alves RT, Rossit AR, Castilho L, Machado RL: Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?. Trans R Soc Trop Med Hyg. 2007, 101: 1042-1044. 10.1016/j.trstmh.2007.04.011.
Article
PubMed
Google Scholar
Duffy PE: Plasmodium in the placenta: parasites, parity, protection, prevention and possibly preeclampsia. Parasitology. 2007, 134: 1877-1881. 10.1017/S0031182007000170.
Article
CAS
PubMed
Google Scholar
Schofield L, Hewitt MC, Evans K, Siomos MA, Seeberger PH: Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature. 2002, 418: 785-789. 10.1038/nature00937.
Article
CAS
PubMed
Google Scholar
Carter R: Transmission blocking malaria vaccines. Vaccine. 2001, 19: 2309-2314. 10.1016/S0264-410X(00)00521-1.
Article
CAS
PubMed
Google Scholar
Saul A: Efficacy model for mosquito stage transmission blocking vaccines for malaria. Parasitology. 2008, 135: 1497-1506. 10.1017/S0031182008000280.
Article
CAS
PubMed
Google Scholar
Saul A: Mosquito stage, transmission blocking vaccines for malaria. Curr Opin Infect Dis. 2007, 20: 476-481. 10.1097/QCO.0b013e3282a95e12.
Article
PubMed
Google Scholar
Miura K, Keister DB, Muratova OV, Sattabongkot J, Long CA, Saul A: Transmission-blocking activity induced by malaria vaccine candidates Pfs25/Pvs25 is a direct and predictable function of antibody titer. Malar J. 2007, 6: 107-10.1186/1475-2875-6-107.
Article
PubMed Central
PubMed
Google Scholar
Kubler-Kielb J, Majadly F, Wu Y, Narum DL, Guo C, Miller LH, Shiloach J, Robbins JB, Schneerson R: Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25. Proc Natl Acad Sci USA. 2007, 104: 293-298. 10.1073/pnas.0609885104.
Article
PubMed Central
CAS
PubMed
Google Scholar
Malkin EM, Durbin AP, Diemert DJ, Sattabongkot J, Wu Y, Miura K, Long CA, Lambert L, Miles AP, Wang J, Stowers A, Miller LH, Saul A: Phase 1 vaccine trial of Pvs25H: a transmission blocking vaccine for Plasmodium vivax malaria. Vaccine. 2005, 23: 3131-3138. 10.1016/j.vaccine.2004.12.019.
Article
CAS
PubMed
Google Scholar
Mlambo G, Maciel J, Kumar N: Murine model for assessment of Plasmodium falciparum transmission-blocking vaccine using transgenic Plasmodium berghei parasites expressing the target antigen Pfs25. Infect Immun. 2008, 76: 2018-2024. 10.1128/IAI.01409-07.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ramjanee S, Robertson JS, Franke-Fayard B, Sinha R, Waters AP, Janse CJ, Wu Y, Blagborough AM, Saul A, Sinden RE: The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials. Vaccine. 2007, 25: 886-894. 10.1016/j.vaccine.2006.09.035.
Article
CAS
PubMed
Google Scholar
Outchkourov N, Vermunt A, Jansen J, Kaan A, Roeffen W, Teelen K, Lasonder E, Braks A, Vegte-Bolmer van de M, Qiu LY, Sauerwein R, Stunnenberg HG: Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies. J Biol Chem. 2007, 282: 17148-17156. 10.1074/jbc.M700948200.
Article
CAS
PubMed
Google Scholar
Outchkourov NS, Roeffen W, Kaan A, Jansen J, Luty A, Schuiffel D, van Gemert GJ, Vegte-Bolmer van de M, Sauerwein RW, Stunnenberg HG: Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice. Proc Natl Acad Sci USA. 2008, 105: 4301-4305. 10.1073/pnas.0800459105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Molineaux L, Gramiccio G: The Garki project: research on the epidemiology and control of malaria in the Sudan savanna of West Africa. 1980, WHO Geneva
Google Scholar
Ong CS, Zhang KY, Eida SJ, Graves PM, Dow C, Looker M, Rogers NC, Chiodini PL, Targett GA: The primary antibody response of malaria patients to Plasmodium falciparum sexual stage antigens which are potential transmission blocking vaccine candidates. Parasite Immunol. 1990, 12: 447-456. 10.1111/j.1365-3024.1990.tb00980.x.
Article
CAS
PubMed
Google Scholar
Bousema JT, Drakeley CJ, Sauerwein RW: Sexual-stage antibody responses to P. falciparum in endemic populations. Curr Mol Med. 2006, 6: 223-229. 10.2174/156652406776055140.
Article
CAS
PubMed
Google Scholar
Peiris JS, Premawansa S, Ranawaka MB, Udagama PV, Munasinghe YD, Nanayakkara MV, Gamage CP, Carter R, David PH, Mendis KN: Monoclonal and polyclonal antibodies both block and enhance transmission of human Plasmodium vivax malaria. Am J Trop Med Hyg. 1988, 39: 26-32.
CAS
PubMed
Google Scholar
Deloron P, Chougnet C: Is immunity to malaria really short-lived?. Parasitol Today. 1992, 8: 375-378. 10.1016/0169-4758(92)90174-Z.
Article
CAS
PubMed
Google Scholar
Struik SS, Riley EM: Does malaria suffer from lack of memory?. Immunol Rev. 2004, 201: 268-290. 10.1111/j.0105-2896.2004.00181.x.
Article
PubMed
Google Scholar
Filipe JA, Riley EM, Drakeley CJ, Sutherland CJ, Ghani AC: Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model. PLoS Comput Biol. 2007, 3: e255-10.1371/journal.pcbi.0030255.
Article
PubMed Central
PubMed
Google Scholar
Saul A, Fay MP: Human immunity and the design of multi-component, single target vaccines. PLoS ONE. 2007, 2: e850-10.1371/journal.pone.0000850.
Article
PubMed Central
PubMed
Google Scholar