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Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

The Original Article was published on 08 December 2015

Erratum to: Malar J (2015) 14:493 DOI 10.1186/s12936-015-1008-5

After publication of the original article [1], it was noticed that Fig. 1 was inadvertently altered during production. While ensuring the Figure was suitable for inclusion and conformed to style guidelines, Fig. 1b was mistakenly cropped in a way that reduced the effectiveness of the Figure. Figure 1 has now been replaced with the correct version in the original article, and is published correctly below.

Fig. 1
figure1

Recombinant proteins expressed in HEK293 cells. a Representation of IT4-VAR19 domain organization and sequence limits of the full-length IT4-VAR19 and the recombinant IT4-VAR19 domains studied (VAR19-NTS-DBLɣ6 and CIDRα1.1). IT4-VAR19 is composed of five Duffy-binding-like domains (shown in green), two cysteine-rich interdomain regions (shown in red), a transmembrane segment and an acidic C terminus sequence (ATS, shown in blue). b SDS-PAGE under reducing and non-reducing conditions of purified VAR19-NTS-DBLɣ6 and CIDRα1.1. c SDS-PAGE under reducing and non-reducing conditions of purified recombinant EPCR proteins (His tagged EPCRH and His/FLAG tagged)

Additionally, Additional file 2 was incorrectly supplied as a duplicate of Additional file 1 during the proofing process. The original article has been updated with the correct file for Additional file 2, ‘Antibodies raised against VAR19-NTS-DBLγ6 inhibit its interaction with EPCR’, which also appears correctly in this erratum.

Reference

  1. 1.

    Nunes-Silva S, et al. Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding. Malar J. 2015;14:493. doi:10.1186/s12936-015-1008-5.

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Correspondence to Benoît Gamain.

Additional information

The online version of the original article can be found under doi:10.1186/s12936-015-1008-5.

Additional file

Additional file 2.

Antibodies raised against VAR19-NTS-DBLγ6 inhibit its interaction with EPCR.

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Nunes-Silva, S., Dechavanne, S., Moussiliou, A. et al. Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding. Malar J 15, 22 (2016). https://doi.org/10.1186/s12936-015-1061-0

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