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Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

  • Sofia Nunes-Silva1, 2, 3, 4,
  • Sébastien Dechavanne1, 2, 3, 4,
  • Azizath Moussiliou4, 5, 6,
  • Natalia Pstrąg1, 2, 3, 4,
  • Jean-Philippe Semblat1, 2, 3, 4,
  • Stéphane Gangnard1, 2, 3, 4,
  • Nicaise Tuikue-Ndam4, 5, 6,
  • Philippe Deloron4, 5, 6,
  • Arnaud Chêne1, 2, 3, 4 and
  • Benoît Gamain1, 2, 3, 4Email author
Malaria Journal201615:22

Published: 11 January 2016

The original article was published in Malaria Journal 2015 14:493

Erratum to: Malar J (2015) 14:493 DOI 10.1186/s12936-015-1008-5

After publication of the original article [1], it was noticed that Fig. 1 was inadvertently altered during production. While ensuring the Figure was suitable for inclusion and conformed to style guidelines, Fig. 1b was mistakenly cropped in a way that reduced the effectiveness of the Figure. Figure 1 has now been replaced with the correct version in the original article, and is published correctly below.
Figure 1
Fig. 1

Recombinant proteins expressed in HEK293 cells. a Representation of IT4-VAR19 domain organization and sequence limits of the full-length IT4-VAR19 and the recombinant IT4-VAR19 domains studied (VAR19-NTS-DBLɣ6 and CIDRα1.1). IT4-VAR19 is composed of five Duffy-binding-like domains (shown in green), two cysteine-rich interdomain regions (shown in red), a transmembrane segment and an acidic C terminus sequence (ATS, shown in blue). b SDS-PAGE under reducing and non-reducing conditions of purified VAR19-NTS-DBLɣ6 and CIDRα1.1. c SDS-PAGE under reducing and non-reducing conditions of purified recombinant EPCR proteins (His tagged EPCRH and His/FLAG tagged)

Additionally, Additional file 2 was incorrectly supplied as a duplicate of Additional file 1 during the proofing process. The original article has been updated with the correct file for Additional file 2, ‘Antibodies raised against VAR19-NTS-DBLγ6 inhibit its interaction with EPCR’, which also appears correctly in this erratum.



Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

Inserm UMR_1134, Paris, France
Université Paris Diderot, Sorbonne Paris Cité, UMR_S1134, Paris, France
Institut National de la Transfusion Sanguine, Paris, France
Laboratory of Excellence GR-Ex, Paris, France
Institut de Recherche pour le développement, UMR_216, Mère et enfant face aux infections tropicales, Paris, France
Faculté de pharmacie, PRES Sorbonne Paris Cité, Paris, France


  1. Nunes-Silva S, et al. Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding. Malar J. 2015;14:493. doi:10.1186/s12936-015-1008-5.PubMedPubMed CentralView ArticleGoogle Scholar


© Nunes-Silva et al. 2016


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