WHOSS. World Malaria Report 2019. Geneva: World Health Organization; 2019.
Google Scholar
Vivax Working Group. Targeting vivax malaria in the Asia Pacific: the Asia Pacific Malaria Elimination Network Vivax Working Group. Malar J. 2015;14:484.
Google Scholar
Gosling RD, Whittaker M, Gueye CS, Fullman N, Baquilod M, Kusriastuti R, et al. Malaria elimination gaining ground in the Asia Pacific. Malar J. 2012;11:346.
PubMed
PubMed Central
Google Scholar
Tessema SK, Raman J, Duffy CW, Ishengoma DS, Amambua-Ngwa A, Greenhouse B. Applying next-generation sequencing to track falciparum malaria in sub-Saharan Africa. Malar J. 2019;18:268.
PubMed
PubMed Central
Google Scholar
Ghansah A, Kamau E, Amambua-Ngwa A, Ishengoma DS, Maiga-Ascofare O, Amenga-Etego L, et al. Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook. Malar J. 2019;18:324.
PubMed
PubMed Central
Google Scholar
Ishengoma DS, Saidi Q, Sibley CH, Roper C, Alifrangis M. Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges. Malar J. 2019;18:267.
PubMed
PubMed Central
Google Scholar
Noedl H, Se Y, Schaecher K, Smith BL, Socheat D, Fukuda MM, et al. Evidence of artemisinin-resistant malaria in western Cambodia. N Engl J Med. 2008;359:2619–20.
CAS
PubMed
Google Scholar
Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, et al. Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2009;361:455–67.
CAS
PubMed
PubMed Central
Google Scholar
Leang R, Taylor WR, Bouth DM, Song L, Tarning J, Char MC, et al. Evidence of Plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: dihydroartemisinin-piperaquine open-label multicenter clinical assessment. Antimicrob Agents Chemother. 2015;59:4719–26.
CAS
PubMed
PubMed Central
Google Scholar
Saunders DL, Vanachayangkul P, Lon C. US Army Malaria Research Program, National Center for Parasitology, Entomology, and Malaria Control, Royal Cambodian Armed Forces. Dihydroartemisinin-piperaquine failure in Cambodia. N Engl J Med. 2014;371:484–5.
CAS
PubMed
Google Scholar
Dalmat R, Naughton B, Kwan-Gett TS, Slyker J, Stuckey EM. Use cases for genetic epidemiology in malaria elimination. Malar J. 2019;18:163.
PubMed
PubMed Central
Google Scholar
Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, et al. A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature. 2014;505:50–5.
PubMed
Google Scholar
Miotto O, Amato R, Ashley EA, MacInnis B, Almagro-Garcia J, Amaratunga C, et al. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nat Genet. 2015;47:226–34.
CAS
PubMed
PubMed Central
Google Scholar
Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411–23.
PubMed
PubMed Central
Google Scholar
Hamilton WL, Amato R, van der Pluijm RW, Jacob CG, Quang HH, Thuy-Nhien NT, et al. Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study. Lancet Infect Dis. 2019;19:943–51.
PubMed
PubMed Central
Google Scholar
Amato R, Lim P, Miotto O, Amaratunga C, Dek D, Pearson RD, et al. Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study. Lancet Infect Dis. 2017;17:164–73.
CAS
PubMed
Google Scholar
Witkowski B, Duru V, Khim N, Ross LS, Saintpierre B, Beghain J, et al. A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study. Lancet Infect Dis. 2017;17:174–83.
CAS
PubMed
PubMed Central
Google Scholar
Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, et al. Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number. Lancet. 2004;364:438–47.
CAS
PubMed
PubMed Central
Google Scholar
Pearson RD, Amato R, Kwiatkowski DP, MalariaGEN Plasmodium falciparum Community Project. An open dataset of Plasmodium falciparum genome variation in 7000 worldwide samples. bioRxiv. 2019. https://doi.org/10.1101/824730.
Article
Google Scholar
Grigg MJ, William T, Menon J, Barber BE, Wilkes CS, Rajahram GS, et al. Efficacy of artesunate-mefloquine for chloroquine-resistant Plasmodium vivax malaria in Malaysia: an open-label, randomized, controlled trial. Clin Infect Dis. 2016;62:1403–11.
CAS
PubMed
PubMed Central
Google Scholar
Ratcliff A, Siswantoro H, Kenangalem E, Wuwung M, Brockman A, Edstein MD, et al. Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia. Trans R Soc Trop Med Hyg. 2007;101:351–9.
CAS
PubMed
PubMed Central
Google Scholar
Leang R, Barrette A, Bouth DM, Menard D, Abdur R, Duong S, et al. Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010. Antimicrob Agents Chemother. 2013;57:818–26.
CAS
PubMed
PubMed Central
Google Scholar
Price RN, Auburn S, Marfurt J, Cheng Q. Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax. Trends Parasitol. 2012;28:522–9.
CAS
PubMed
PubMed Central
Google Scholar
Pava Z, Handayuni I, Wirjanata G, To S, Trianty L, Noviyanti R, et al. Expression of Plasmodium vivax crt-o is related to parasite stage but not ex vivo chloroquine susceptibility. Antimicrob Agents Chemother. 2016;60:361–7.
CAS
PubMed
Google Scholar
Melo GC, Monteiro WM, Siqueira AM, Silva SR, Magalhaes BM, Alencar AC, et al. Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon. PLoS ONE. 2014;9:e105922.
PubMed
PubMed Central
Google Scholar
Sa JM, Kaslow SR, Moraes Barros RR, Brazeau NF, Parobek CM, Tao D, et al. Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross. Nat Commun. 2019;10:4300.
PubMed
PubMed Central
Google Scholar
Imwong M, Suwannasin K, Kunasol C, Sutawong K, Mayxay M, Rekol H, et al. The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study. Lancet Infect Dis. 2017;17:491–7.
PubMed
PubMed Central
Google Scholar
Havryliuk T, Ferreira MU. A closer look at multiple-clone Plasmodium vivax infections: detection methods, prevalence and consequences. Mem Inst Oswaldo Cruz. 2009;104:67–73.
PubMed
Google Scholar
Anderson TJ, Haubold B, Williams JT, Estrada-Franco JG, Richardson L, Mollinedo R, et al. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol Biol Evol. 2000;7:1467–82.
Google Scholar
Gunawardena S, Ferreira MU, Kapilananda GM, Wirth DF, Karunaweera ND. The Sri Lankan paradox: high genetic diversity in Plasmodium vivax populations despite decreasing levels of malaria transmission. Parasitology. 2014;141:880–90.
PubMed
Google Scholar
Wangchuk S, Drukpa T, Penjor K, Peldon T, Dorjey Y, Dorji K, et al. Where chloroquine still works: the genetic make-up and susceptibility of Plasmodium vivax to chloroquine plus primaquine in Bhutan. Malar J. 2016;15:277.
PubMed
PubMed Central
Google Scholar
Pava Z, Handayuni I, Trianty L, Utami RAS, Tirta YK, Puspitasari AM, et al. Passively versus actively detected malaria: similar genetic diversity but different complexity of infection. Am J Trop Med Hyg. 2017;97:1788–96.
CAS
PubMed
PubMed Central
Google Scholar
Auburn S, Campino S, Miotto O, Djimde AA, Zongo I, Manske M, et al. Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data. PLoS ONE. 2012;7:e32891.
CAS
PubMed
PubMed Central
Google Scholar
Galinsky K, Valim C, Salmier A, de Thoisy B, Musset L, Legrand E, et al. COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data. Malar J. 2015;14:4.
PubMed
PubMed Central
Google Scholar
Snounou G, Beck HP. The use of PCR genotyping in the assessment of recrudescence or reinfection after antimalarial drug treatment. Parasitol Today. 1998;14:462–7.
CAS
PubMed
Google Scholar
Koepfli C, Mueller I, Marfurt J, Goroti M, Sie A, Oa O, et al. Evaluation of Plasmodium vivax genotyping markers for molecular monitoring in clinical trials. J Infect Dis. 2009;199:1074–80.
CAS
PubMed
Google Scholar
Imwong M, Sudimack D, Pukrittayakamee S, Osorio L, Carlton JM, Day NP, et al. Microsatellite variation, repeat array length, and population history of Plasmodium vivax. Mol Biol Evol. 2006;23:1016–8.
CAS
PubMed
Google Scholar
Gunawardena S, Karunaweera ND, Ferreira MU, Phone-Kyaw M, Pollack RJ, Alifrangis M, et al. Geographic structure of Plasmodium vivax: microsatellite analysis of parasite populations from Sri Lanka, Myanmar, and Ethiopia. Am J Trop Med Hyg. 2010;82:235–42.
CAS
PubMed
PubMed Central
Google Scholar
Anderson TJ, Su XZ, Bockarie M, Lagog M, Day KP. Twelve microsatellite markers for characterization of Plasmodium falciparum from finger-prick blood samples. Parasitology. 1999;119(Pt 2):113–25.
CAS
PubMed
Google Scholar
Zhong D, Koepfli C, Cui L, Yan G. Molecular approaches to determine the multiplicity of Plasmodium infections. Malar J. 2018;17:172.
PubMed
PubMed Central
Google Scholar
Lerch A, Koepfli C, Hofmann NE, Kattenberg JH, Rosanas-Urgell A, Betuela I, et al. Longitudinal tracking and quantification of individual Plasmodium falciparum clones in complex infections. Sci Rep. 2019;9:3333.
PubMed
PubMed Central
Google Scholar
Gruenberg M, Lerch A, Beck HP, Felger I. Amplicon deep sequencing improves Plasmodium falciparum genotyping in clinical trials of antimalarial drugs. Sci Rep. 2019;9:17790.
PubMed
PubMed Central
Google Scholar
Lerch A, Koepfli C, Hofmann NE, Messerli C, Wilcox S, Kattenberg JH, et al. Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections. BMC Genomics. 2017;18:864.
PubMed
PubMed Central
Google Scholar
Lin JT, Hathaway NJ, Saunders DL, Lon C, Balasubramanian S, Kharabora O, et al. Using amplicon deep sequencing to detect genetic signatures of Plasmodium vivax relapse. J Infect Dis. 2015;212:999–1008.
CAS
PubMed
PubMed Central
Google Scholar
Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJ, Holmes SP. DADA2: high-resolution sample inference from Illumina amplicon data. Nat Methods. 2016;13:581–3.
CAS
PubMed
PubMed Central
Google Scholar
Hathaway NJ, Parobek CM, Juliano JJ, Bailey JA. SeekDeep: single-base resolution de novo clustering for amplicon deep sequencing. Nucleic Acids Res. 2018;46:e21.
CAS
PubMed
Google Scholar
Early AM, Daniels RF, Farrell TM, Grimsby J, Volkman SK, Wirth DF, et al. Detection of low-density Plasmodium falciparum infections using amplicon deep sequencing. Malar J. 2019;18:219.
PubMed
PubMed Central
Google Scholar
Abdullah NR, Barber BE, William T, Norahmad NA, Satsu UR, Muniandy PK, et al. Plasmodium vivax population structure and transmission dynamics in Sabah Malaysia. PLoS ONE. 2013;8:e82553.
PubMed
PubMed Central
Google Scholar
Auburn S, Benavente ED, Miotto O, Pearson RD, Amato R, Grigg MJ, et al. Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics. Nat Commun. 2018;9:2585.
PubMed
PubMed Central
Google Scholar
Hamedi Y, Sharifi-Sarasiabi K, Dehghan F, Safari R, To S, Handayuni I, et al. Molecular epidemiology of P. vivax in Iran: high diversity and complex sub-structure using neutral markers, but no evidence of Y976F mutation at pvmdr1. PLoS ONE. 2016;11:e0166124.
PubMed
PubMed Central
Google Scholar
Waltmann A, Koepfli C, Tessier N, Karl S, Fola A, Darcy AW, et al. Increasingly inbred and fragmented populations of Plasmodium vivax associated with the eastward decline in malaria transmission across the Southwest Pacific. PLoS Negl Trop Dis. 2018;12:e0006146.
PubMed
PubMed Central
Google Scholar
Nkhoma SC, Nair S, Al-Saai S, Ashley E, McGready R, Phyo AP, et al. Population genetic correlates of declining transmission in a human pathogen. Mol Ecol. 2013;22:273–85.
PubMed
Google Scholar
Daniels RF, Schaffner SF, Wenger EA, Proctor JL, Chang HH, Wong W, et al. Modeling malaria genomics reveals transmission decline and rebound in Senegal. Proc Natl Acad Sci USA. 2015;112:7067–72.
CAS
PubMed
Google Scholar
Elyazar IR, Hay SI, Baird JK. Malaria distribution, prevalence, drug resistance and control in Indonesia. Adv Parasitol. 2011;74:41–175.
PubMed
PubMed Central
Google Scholar
Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, et al. Mapping malaria by combining parasite genomic and epidemiologic data. BMC Med. 2018;16:190.
PubMed
PubMed Central
Google Scholar
Tessema S, Wesolowski A, Chen A, Murphy M, Wilheim J, Mupiri AR, et al. Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa. Elife. 2019;8:e43510.
PubMed
PubMed Central
Google Scholar
Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, et al. Mapping imported malaria in Bangladesh using parasite genetic and human mobility data. Elife. 2019;8:e43510.
Google Scholar
Wright S. Isolation by distance. Genetics. 1943;28:114–38.
CAS
PubMed
PubMed Central
Google Scholar
Auburn S, Barry AE. Dissecting malaria biology and epidemiology using population genetics and genomics. Int J Parasitol. 2017;47:77–85.
PubMed
Google Scholar
Taylor AR, Schaffner SF, Cerqueira GC, Nkhoma SC, Anderson TJC, Sriprawat K, et al. Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent. PLoS Genet. 2017;13:e1007065.
PubMed
PubMed Central
Google Scholar
Henden L, Lee S, Mueller I, Barry A, Bahlo M. Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens. PLoS Genet. 2018;14:e1007279.
PubMed
PubMed Central
Google Scholar
Schaffner SF, Taylor AR, Wong W, Wirth DF, Neafsey DE. hmmIBD: software to infer pairwise identity by descent between haploid genotypes. Malar J. 2018;17:196.
PubMed
PubMed Central
Google Scholar
Zhu SJ, Almagro-Garcia J, McVean G. Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data. Bioinformatics. 2018;34:9–15.
CAS
PubMed
Google Scholar
Noviyanti R, Coutrier F, Utami RA, Trimarsanto H, Tirta YK, Trianty L, et al. Contrasting transmission dynamics of co-endemic Plasmodium vivax and P. falciparum: implications for malaria control and elimination. PLoS Negl Trop Dis. 2015;9:e0003739.
PubMed
PubMed Central
Google Scholar
Fola AA, Nate E, Abby Harrison GL, Barnadas C, Hetzel MW, Iga J, et al. Nationwide genetic surveillance of Plasmodium vivax in Papua New Guinea reveals heterogeneous transmission dynamics and routes of migration amongst subdivided populations. Infect Genet Evol. 2018;58:83–95.
PubMed
Google Scholar
Liu Y, Hsiang MS, Zhou H, Wang W, Cao Y, Gosling RD, et al. Malaria in overseas labourers returning to China: an analysis of imported malaria in Jiangsu Province, 2001–2011. Malar J. 2014;13:29.
PubMed
PubMed Central
Google Scholar
Lai S, Sun J, Ruktanonchai NW, Zhou S, Yu J, Routledge I, et al. Changing epidemiology and challenges of malaria in China towards elimination. Malar J. 2019;18:107.
PubMed
PubMed Central
Google Scholar
Trimarsanto H, Amato R, Pearson RD, Sutanto E, Noviyanti R, Trianty L, et al. A molecular barcode and online tool to identify and map imported infection with Plasmodium vivax. bioRxiv. 2019. https://doi.org/10.1101/776781.
Article
Google Scholar
Wang D, Li S, Cheng Z, Xiao N, Cotter C, Hwang J, et al. Transmission risk from imported Plasmodium vivax malaria in the China-Myanmar border region. Emerg Infect Dis. 2015;21:1861–4.
PubMed
PubMed Central
Google Scholar
Cunningham J, Jones S, Gatton ML, Barnwell JW, Cheng Q, Chiodini PL, et al. A review of the WHO malaria rapid diagnostic test product testing programme (2008–2018): performance, procurement and policy. Malar J. 2019;18:387.
PubMed
PubMed Central
Google Scholar
Cheng Q, Gatton ML, Barnwell J, Chiodini P, McCarthy J, Bell D, et al. Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3: a review and recommendations for accurate reporting. Malar J. 2014;13:283.
PubMed
PubMed Central
Google Scholar
White NJ, Imwong M. Relapse. Adv Parasitol. 2012;80:113–50.
PubMed
Google Scholar
Ross A, Koepfli C, Schoepflin S, Timinao L, Siba P, Smith T, et al. The incidence and differential seasonal patterns of Plasmodium vivax primary infections and relapses in a cohort of children in Papua New Guinea. PLoS Negl Trop Dis. 2016;10:e0004582.
PubMed
PubMed Central
Google Scholar
Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, et al. Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. J Infect Dis. 2007;195:927–33.
CAS
PubMed
Google Scholar
Bright AT, Manary MJ, Tewhey R, Arango EM, Wang T, Schork NJ, et al. A high resolution case study of a patient with recurrent Plasmodium vivax infections shows that relapses were caused by meiotic siblings. PLoS Negl Trop Dis. 2014;8:e2882.
PubMed
PubMed Central
Google Scholar
Popovici J, Pierce-Friedrich L, Kim S, Bin S, Run V, Lek D, et al. Recrudescence, reinfection, or relapse? A more rigorous framework to assess chloroquine efficacy for Plasmodium vivax malaria. J Infect Dis. 2019;219:315–22.
CAS
PubMed
Google Scholar
Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN, Ghansah A, et al. Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification. Malar J. 2016;15:597.
PubMed
PubMed Central
Google Scholar
Cowell AN, Loy DE, Sundararaman SA, Valdivia H, Fisch K, Lescano AG, et al. Selective whole-genome amplification is a robust method that enables scalable whole-genome sequencing of Plasmodium vivax from unprocessed clinical samples. mBio. 2017;8:e02257–e2316.
CAS
PubMed
PubMed Central
Google Scholar
Nag S, Ursing J, Rodrigues A, Crespo M, Krogsgaard C, Lund O, et al. Proof of concept: used malaria rapid diagnostic tests applied for parallel sequencing for surveillance of molecular markers of anti-malarial resistance in Bissau, Guinea-Bissau during 2014–2017. Malar J. 2019;18:252.
PubMed
PubMed Central
Google Scholar
Trimarsanto H, Benavente ED, Noviyanti R, Utami RA, Trianty L, Pava Z, et al. VivaxGEN: An open access platform for comparative analysis of short tandem repeat genotyping data in Plasmodium vivax populations. PLoS Negl Trop Dis. 2017;11:e0005465.
PubMed
PubMed Central
Google Scholar
Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J, Amaratunga C, et al. Genomic analysis of local variation and recent evolution in Plasmodium vivax. Nat Genet. 2016;48:959–64.
CAS
PubMed
PubMed Central
Google Scholar
Thriemer K, Ley B, Bobogare A, Dysoley L, Alam MS, Pasaribu AP, et al. Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group. Malar J. 2017;16:141.
PubMed
PubMed Central
Google Scholar
Cowman AF, Galatis D, Thompson JK. Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proc Natl Acad Sci USA. 1994;91:1143–7.
CAS
PubMed
Google Scholar
Reed MB, Saliba KJ, Caruana SR, Kirk K, Cowman AF. Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature. 2000;403:906–9.
CAS
PubMed
Google Scholar
Veiga MI, Dhingra SK, Henrich PP, Straimer J, Gnadig N, Uhlemann AC, et al. Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies. Nat Commun. 2016;7:11553.
CAS
PubMed
PubMed Central
Google Scholar
Simpson JA, Jamsen KM, Anderson TJ, Zaloumis S, Nair S, Woodrow C, et al. Nonlinear mixed-effects modelling of in vitro drug susceptibility and molecular correlates of multidrug resistant Plasmodium falciparum. PLoS ONE. 2013;8:e69505.
CAS
PubMed
PubMed Central
Google Scholar
Warhurst DC. A molecular marker for chloroquine-resistant falciparum malaria. N Engl J Med. 2001;344:299–302.
CAS
PubMed
Google Scholar
Duraisingh MT, Cowman AF. Contribution of the pfmdr1 gene to antimalarial drug-resistance. Acta Trop. 2005;94:181–90.
CAS
PubMed
Google Scholar
Gregson A, Plowe CV. Mechanisms of resistance of malaria parasites to antifolates. Pharmacol Rev. 2005;57:117–45.
CAS
PubMed
Google Scholar
Hyde JE. Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs. Microbes Infect. 2002;4:165–74.
CAS
PubMed
Google Scholar
Tinto H, Guekoun L, Zongo I, Guiguemde RT, D'Alessandro U, Ouedraogo JB. Chloroquine-resistance molecular markers (Pfcrt T76 and Pfmdr-1 Y86) and amodiaquine resistance in Burkina Faso. Trop Med Int Health. 2008;13:238–40.
CAS
PubMed
Google Scholar
Suwanarusk R, Russell B, Chavchich M, Chalfein F, Kenangalem E, Kosaisavee V, et al. Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms. PLoS ONE. 2007;2:e1089.
PubMed
PubMed Central
Google Scholar
Brega S, Meslin B, de Monbrison F, Severini C, Gradoni L, Udomsangpetch R, et al. Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity. J Infect Dis. 2005;191:272–7.
CAS
PubMed
Google Scholar
Imwong M, Pukrittayakamee S, Cheng Q, Moore C, Looareesuwan S, Snounou G, et al. Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand. Antimicrob Agents Chemother. 2005;49:4393–5.
CAS
PubMed
PubMed Central
Google Scholar
Korsinczky M, Fischer K, Chen N, Baker J, Rieckmann K, Cheng Q. Sulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site. Antimicrob Agents Chemother. 2004;48:2214–22.
CAS
PubMed
PubMed Central
Google Scholar
Marfurt J, de Monbrison F, Brega S, Barbollat L, Muller I, Sie A, et al. Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1. J Infect Dis. 2008;198:409–17.
PubMed
Google Scholar
Auliff A, Wilson DW, Russell B, Gao Q, Chen N, le Anh N, et al. Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs. Am J Trop Med Hyg. 2006;75:617–21.
CAS
PubMed
Google Scholar
Tjitra E, Baker J, Suprianto S, Cheng Q, Anstey NM. Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations. Antimicrob Agents Chemother. 2002;46:3947–53.
CAS
PubMed
PubMed Central
Google Scholar
Hastings MD, Maguire JD, Bangs MJ, Zimmerman PA, Reeder JC, Baird JK, et al. Novel Plasmodium vivax dhfr alleles from the Indonesian Archipelago and Papua New Guinea: association with pyrimethamine resistance determined by a Saccharomyces cerevisiae expression system. Antimicrob Agents Chemother. 2005;49:733–40.
CAS
PubMed
PubMed Central
Google Scholar
Zakeri S, Motmaen SR, Afsharpad M, Djadid ND. Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East. Malar J. 2009;8:20.
PubMed
PubMed Central
Google Scholar
Rungsihirunrat K, Sibley CH, Mungthin M, Na-Bangchang K. Geographical distribution of amino acid mutations in Plasmodium vivax DHFR and DHPS from malaria endemic areas of Thailand. Am J Trop Med Hyg. 2008;78:462–7.
CAS
PubMed
Google Scholar
Suwanarusk R, Chavchich M, Russell B, Jaidee A, Chalfein F, Barends M, et al. Amplification of pvmdr1 associated with multidrug-resistant Plasmodium vivax. J Infect Dis. 2008;198:1558–644.
CAS
PubMed
PubMed Central
Google Scholar
Auburn S, Serre D, Pearson R, Amato R, Sriprawat K, To S, et al. Genomic analysis reveals a common breakpoint in amplifications of the Plasmodium vivax multidrug resistance 1 locus in Thailand. J Infect Dis. 2016;214:1235–42.
CAS
PubMed
PubMed Central
Google Scholar
Imwong M, Pukrittayakamee S, Pongtavornpinyo W, Nakeesathit S, Nair S, Newton P, et al. Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. Antimicrob Agents Chemother. 2008;52:2657–9.
CAS
PubMed
PubMed Central
Google Scholar
Choi KM, Choi YK, Kang YA, Seo SY, Lee HW, Cho SH, et al. Study of the genetic discrimination between imported and autochthonous cases of malaria in South Korea. J Travel Med. 2011;18:63–6.
PubMed
Google Scholar
Severini C, Menegon M, Gradoni L, Majori G. Use of the Plasmodium vivax merozoite surface protein 1 gene sequence analysis in the investigation of an introduced malaria case in Italy. Acta Trop. 2002;84:151–7.
CAS
PubMed
Google Scholar
Severini C, Menegon M, Di Luca M, Abdullaev I, Majori G, Razakov SA, et al. Risk of Plasmodium vivax malaria reintroduction in Uzbekistan: genetic characterization of parasites and status of potential malaria vectors in the Surkhandarya region. Trans R Soc Trop Med Hyg. 2004;98:585–92.
CAS
PubMed
Google Scholar
Liu Y, Auburn S, Cao J, Trimarsanto H, Zhou H, Gray KA, Clark TG, et al. Genetic diversity and population structure of Plasmodium vivax in Central China. Malar J. 2014;13:262.
CAS
PubMed
PubMed Central
Google Scholar
Kim JY, Goo YK, Zo YG, Ji SY, Trimarsanto H, To S, et al. Further evidence of increasing diversity of Plasmodium vivax in the Republic of Korea in recent years. PLoS ONE. 2016;11:e0151514.
PubMed
PubMed Central
Google Scholar
Rodrigues PT, Alves JM, Santamaria AM, Calzada JE, Xayavong M, Parise M, da Silva AJ, Ferreira MU, et al. Using mitochondrial genome sequences to track the origin of imported Plasmodium vivax infections diagnosed in the United States. Am J Trop Med Hyg. 2014;90:1102–8.
PubMed
PubMed Central
Google Scholar
Iwagami M, Hwang SY, Fukumoto M, Hayakawa T, Tanabe K, Kim SH, et al. Geographical origin of Plasmodium vivax in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome. Malar J. 2010;9:184.
PubMed
PubMed Central
Google Scholar
Joy DA, Feng X, Mu J, Furuya T, Chotivanich K, Krettli AU, et al. Early origin and recent expansion of Plasmodium falciparum. Science. 2003;300:318–21.
CAS
PubMed
Google Scholar
Conway DJ, Fanello C, Lloyd JM, Al-Joubori BM, Baloch AH, Somanath SD, et al. Origin of Plasmodium falciparum malaria is traced by mitochondrial DNA. Mol Biochem Parasitol. 2000;111:163–71.
CAS
PubMed
Google Scholar
Preston MD, Campino S, Assefa SA, Echeverry DF, Ocholla H, Amambua-Ngwa A, et al. A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. Nat Commun. 2014;5:4052.
CAS
PubMed
PubMed Central
Google Scholar
Baniecki ML, Faust AL, Schaffner SF, Park DJ, Galinsky K, Daniels RF, et al. Development of a single nucleotide polymorphism barcode to genotype Plasmodium vivax infections. PLoS Negl Trop Dis. 2015;9:e0003539.
PubMed
PubMed Central
Google Scholar
Daniels R, Volkman SK, Milner DA, Mahesh N, Neafsey DE, Park DJ, et al. A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking. Malar J. 2008;7:223.
PubMed
PubMed Central
Google Scholar
Tessema SK, Hathaway NJ, Teyssier NB, Murphy M, Chen A, Aydemir O, et al. Sensitive, highly multiplexed sequencing of microhaplotypes from the Plasmodium falciparum heterozygome. bioRxiv. 2020. https://doi.org/10.1101/2020.02.25.964536.
Article
Google Scholar
Miotto O, Sekihara M, Tachibana S, Yamauchi M, Pearson RD, Amato R, Gonçalves S, M. S, Noviyanti R, Marfurt J, et al. Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea. bioRxiv 2019.
Taylor AR, Watson JA, Chu CS, Puaprasert K, Duanguppama J, Day NPJ, Nosten F, Neafsey DE, Buckee CO, Imwong M, White NJ. Resolving the cause of recurrent Plasmodium vivax malaria probabilistically. Nat Commun. 2019;10:5595.
CAS
PubMed
PubMed Central
Google Scholar