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  1. Appropriate treatment of life-threatening Plasmodium falciparum malaria requires in-patient care. Although the proportion of severe cases accessing in-patient care in endemic settings strongly affects overall cas...

    Authors: Flavia Camponovo, Caitlin A. Bever, Katya Galactionova, Thomas Smith and Melissa A. Penny
    Citation: Malaria Journal 2017 16:1
  2. Reliable and comprehensive information on the burden of malaria is critical for guiding national and international efforts in malaria control. The purpose of this review is to provide an overview of published ...

    Authors: Felix Koukouikila-Koussounda and Francine Ntoumi
    Citation: Malaria Journal 2016 15:598
  3. Translating genomic technologies into healthcare applications for the malaria parasite Plasmodium falciparum has been limited by the technical and logistical difficulties of obtaining high quality clinical sample...

    Authors: Samuel O. Oyola, Cristina V. Ariani, William L. Hamilton, Mihir Kekre, Lucas N. Amenga-Etego, Anita Ghansah, Gavin G. Rutledge, Seth Redmond, Magnus Manske, Dushyanth Jyothi, Chris G. Jacob, Thomas D. Otto, Kirk Rockett, Chris I. Newbold, Matthew Berriman and Dominic P. Kwiatkowski
    Citation: Malaria Journal 2016 15:597
  4. Encouraging advances in the control of Plasmodium falciparum malaria have been observed across much of Africa in the past decade. However, regions of high relative prevalence and transmission that remain unaddres...

    Authors: Benjamin L. Rice, Christopher D. Golden, Evelin Jean Gasta Anjaranirina, Carolina Mastella Botelho, Sarah K. Volkman and Daniel L. Hartl
    Citation: Malaria Journal 2016 15:596
  5. Despite the declining burden of malaria in China, the disease remains a significant public health problem with periodic outbreaks and spatial variation across the country. A better understanding of the spatial...

    Authors: Samuel H. Hundessa, Gail Williams, Shanshan Li, Jinpeng Guo, Linping Chen, Wenyi Zhang and Yuming Guo
    Citation: Malaria Journal 2016 15:595
  6. Active community participation in malaria control is key to achieving malaria pre-elimination in Rwanda. This paper describes development, implementation and evaluation of a community-based malaria elimination...

    Authors: Chantal Marie Ingabire, Emmanuel Hakizimana, Fredrick Kateera, Alexis Rulisa, Bart Van Den Borne, Ingmar Nieuwold, Claude Muvunyi, Constantianus J. M. Koenraadt, Michele Van Vugt, Leon Mutesa and Jane Alaii
    Citation: Malaria Journal 2016 15:594
  7. Plasmodium falciparum gametocytes are vital to sustaining malaria transmission. Parasite densities, multiplicity of infection as well as asexual genotype are features that have been fo...

    Authors: Ruth Ayanful-Torgby, Akua Oppong, Joana Abankwa, Festus Acquah, Kimberly C. Williamson and Linda Eva Amoah
    Citation: Malaria Journal 2016 15:592
  8. The use of malaria infection prevalence among febrile patients at clinics has a potential to be a valuable epidemiological surveillance tool. However, routine data are incomplete and not all fevers are tested....

    Authors: Sophie Githinji, Abdisalan M. Noor, Josephine Malinga, Peter M. Macharia, Rebecca Kiptui, Ahmeddin Omar, Kiambo Njagi, Ejersa Waqo and Robert W. Snow
    Citation: Malaria Journal 2016 15:591
  9. Although malaria disease in urban and peri-urban areas of sub-Saharan Africa is a growing concern, the epidemiologic patterns and drivers of transmission in these settings remain poorly understood. Factors ass...

    Authors: Don P. Mathanga, Atupele Kapito Tembo, Themba Mzilahowa, Andy Bauleni, Kondwani Mtimaukenena, Terrie E. Taylor, Clarissa Valim, Edward D. Walker and Mark L. Wilson
    Citation: Malaria Journal 2016 15:590
  10. The wide spread mosquito Culex pipiens pipiens have two forms molestus and pipiens which frequently hybridize. The two forms have behavioural and physiological differences affecting habitat requirements and host ...

    Authors: Josué Martínez-de la Puente, Martina Ferraguti, Santiago Ruiz, David Roiz, Ramón C. Soriguer and Jordi Figuerola
    Citation: Malaria Journal 2016 15:589
  11. Due to the ability of the 8-aminoquinolines (8AQs) to kill different stages of the malaria parasite, primaquine (PQ) and tafenoquine (TQ) are vital for causal prophylaxis and the eradication of erythrocytic Plasm...

    Authors: Erin E. Milner, Jonathan Berman, Diana Caridha, Samuel P. Dickson, Mark Hickman, Patricia J. Lee, Sean R. Marcsisin, Lisa T. Read, Norma Roncal, Brian A. Vesely, Lisa H. Xie, Jing Zhang, Ping Zhang and Qigui Li
    Citation: Malaria Journal 2016 15:588
  12. Severe malaria is a leading cause of morbidity and mortality in under-fives in sub-Saharan Africa. Recently quinine has been replaced by artesunate as the first-line drug in the treatment of severe malaria in ...

    Authors: Daniel Ethe Maka, Andreas Chiabi, Bolaji Obadeyi, Evelyn Mah, Séraphin Nguefack, Pamela Nana, Wilfred Mbacham and Elie Mbonda
    Citation: Malaria Journal 2016 15:587
  13. The successful control of malaria vectors requires the control of both the larval and adult stages. The adult control methods through indoor residual spraying (IRS) and use of long-lasting insecticidal nets (L...

    Authors: Mulamuli Mpofu, Piet Becker, Kaka Mudambo and Christiaan de Jager
    Citation: Malaria Journal 2016 15:586
  14. As global research investment increases, attention inevitably turns to assessing and measuring the outcomes and impact from research programmes. Research can have many different outcomes such as producing adva...

    Authors: Jo-Ann Mulligan and Lesong Conteh
    Citation: Malaria Journal 2016 15:585
  15. Plasmodium falciparum resistance to anti-malarial drugs remains a major obstacle to malaria control and elimination. The parasite has developed resistance to every anti-malarial drug i...

    Authors: Sydney Mwanza, Sudhaunshu Joshi, Michael Nambozi, Justin Chileshe, Phidelis Malunga, Jean-Bertin Bukasa Kabuya, Sebastian Hachizovu, Christine Manyando, Modest Mulenga and Miriam Laufer
    Citation: Malaria Journal 2016 15:584
  16. Recent reports of emergence and spread of artemisinin resistance in the Southeast Asia region, including Myanmar, pose a greater threat to malaria control and elimination in India. Whole genome sequencing stud...

    Authors: Neelima Mishra, Ram Suresh Bharti, Prashant Mallick, Om Prakash Singh, Bina Srivastava, Roma Rana, Sobhan Phookan, Hardev Prasad Gupta, Pascal Ringwald and Neena Valecha
    Citation: Malaria Journal 2016 15:583
  17. The widespread emergence of resistance to pyrethroids is a major threat to the gains made in malaria control. To monitor the presence and possible emergence of resistance against a variety of insecticides used...

    Authors: Emmanuel Hakizimana, Corine Karema, Dunia Munyakanage, Gad Iranzi, John Githure, Jon Eric Tongren, Willem Takken, Agnes Binagwaho and Constantianus J. M. Koenraadt
    Citation: Malaria Journal 2016 15:582
  18. Levels of both angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) correlate with malaria disease severity and are proposed as biomarkers and possible therapeutic targets. To establish their role in malaria, a s...

    Authors: Gerdie M. de Jong, Jasper J. Slager, Annelies Verbon, Jaap J. van Hellemond and Perry J. J. van Genderen
    Citation: Malaria Journal 2016 15:581
  19. Long-lasting insecticidal nets (LLINs) are known to be highly effective in reducing malaria transmission, morbidity and mortality. However, among those owning an LLIN, use rates are often suboptimal. A reporte...

    Authors: Mulako S. Jaeger, Olivier J. T. Briët, Joseph Keating, Collins K. Ahorlu, Joshua O. Yukich, Samuel Oppong, Peter Nardini and Constanze Pfeiffer
    Citation: Malaria Journal 2016 15:580
  20. The emergence of artemisinin-resistant Plasmodium falciparum strains poses a serious challenge to the control of malaria. This necessitates the development of new anti-malarial drugs. Previous studies have shown ...

    Authors: Abebe Genetu Bayih, Asongna Folefoc, Abu Naser Mohon, Scott Eagon, Marc Anderson and Dylan R. Pillai
    Citation: Malaria Journal 2016 15:579
  21. Outdoor malaria transmission is becoming an increasingly important problem in malaria control in Africa. Larval control is a promising intervention as it can target both indoor and outdoor biting mosquitoes. H...

    Authors: Yaw A. Afrane, Nixon G. Mweresa, Christine L. Wanjala, Thomas M. Gilbreath III, Guofa Zhou, Ming-Chieh Lee, Andrew K. Githeko and Guiyun Yan
    Citation: Malaria Journal 2016 15:577
  22. Malaria is a worldwide public health problem; parasites from the genus Plasmodium spp. are the aetiological agent of this disease. The parasite is mainly diagnosed by microscope-based techniques. However, these h...

    Authors: Carlos Hernando Niño, Juan Ricardo Cubides, Paola Andrea Camargo-Ayala, Carlos Arturo Rodríguez-Celis, Teódulo Quiñones, Moisés Tomás Cortés-Castillo, Lizeth Sánchez-Suárez, Ricardo Sánchez, Manuel Elkin Patarroyo and Manuel Alfonso Patarroyo
    Citation: Malaria Journal 2016 15:576
  23. Malawi experienced prolonged use of sulfadoxine/pyrimethamine (SP) as the front-line anti-malarial drug, with early replacement of chloroquine and delayed introduction of artemisinin-based combination therapy....

    Authors: Matt Ravenhall, Ernest Diez Benavente, Mwapatsa Mipando, Anja T. R. Jensen, Colin J. Sutherland, Cally Roper, Nuno Sepúlveda, Dominic P. Kwiatkowski, Jacqui Montgomery, Kamija S. Phiri, Anja Terlouw, Alister Craig, Susana Campino, Harold Ocholla and Taane G. Clark
    Citation: Malaria Journal 2016 15:575
  24. Malaria in pregnancy is a major cause of adverse maternal and fetal outcomes. Intermittent preventive treatment with sulfadoxine–pyrimethamine (IPTp-SP) is one of the control strategies promoted by WHO. In res...

    Authors: Deborah Almond, Mwayi Madanitsa, Victor Mwapasa, Linda Kalilani-Phiri, Jayne Webster, Feiko ter Kuile and Lucy Paintain
    Citation: Malaria Journal 2016 15:574
  25. In recent years, malaria (Plasmodium vivax and Plasmodium falciparum) has been successfully controlled in the Ecuador–Peru coastal border region. The aim of this study was to document this control effort and to i...

    Authors: Lyndsay K. Krisher, Jesse Krisher, Mariano Ambuludi, Ana Arichabala, Efrain Beltrán-Ayala, Patricia Navarrete, Tania Ordoñez, Mark E. Polhemus, Fernando Quintana, Rosemary Rochford, Mercy Silva, Juan Bazo and Anna M. Stewart-Ibarra
    Citation: Malaria Journal 2016 15:573
  26. The spread of Plasmodium falciparum resistance to artemisinin derivatives in Southeast Asia is a major source of concern and the emergence of resistance in Africa would have dramatic consequences, by increasing m...

    Authors: Sandie Menard, Joëlle Njila Tchoufack, Christelle Ngou Maffo, Sandrine E. Nsango, Xavier Iriart, Luc Abate, Majoline Tchioffo Tsapi, Parfait H. Awono-Ambéné, Francis A. Abega Mekongo, Isabelle Morlais and Antoine Berry
    Citation: Malaria Journal 2016 15:572
  27. Reactive case detection is an approach that has been proposed as a tool for malaria elimination in low-transmission settings. It is an intuitively justified approach based on the concept of space–time clusteri...

    Authors: Daniel M. Parker, Jordi Landier, Lorenz von Seidlein, Arjen Dondorp, Lisa White, Borimas Hanboonkunupakarn, Richard J. Maude and François H. Nosten
    Citation: Malaria Journal 2016 15:571
  28. Plasmodium vivax is considered to be absent from western Africa, where the prevalence of Duffy-negative red blood cell phenotype proves to be high. Several studies have, however, detec...

    Authors: Philippe Poirier, Cécile Doderer-Lang, Pascal S. Atchade, Jean-Philippe Lemoine, Marie-Louise Coquelin de l’Isle, Ahmed Abou-bacar, Alexander W. Pfaff, Julie Brunet, Lydia Arnoux, Elodie Haar, Denis Filisetti, Sylvie Perrotey, Nicodeme W. Chabi, Casimir D. Akpovi, Ludovic Anani, André Bigot…
    Citation: Malaria Journal 2016 15:570
  29. Malaria remains an important cause of morbidity and mortality in India. Though many comprehensive studies have been carried out in Africa and Southeast Asia to characterize and examine determinants of Plasmodium ...

    Authors: Laura Chery, Jennifer N. Maki, Anjali Mascarenhas, Jayashri T. Walke, Pooja Gawas, Anvily Almeida, Mezia Fernandes, Marina Vaz, Rakesh Ramanan, Diksha Shirodkar, Maria Bernabeu, Suresh Kumar Manoharan, Ligia Pereira, Rashmi Dash, Ambika Sharma, Riaz Basha Shaik…
    Citation: Malaria Journal 2016 15:569
  30. Many malaria-endemic countries have implemented national community health worker (CHW) programmes to serve remote populations that have poor access to malaria diagnosis and treatment. Despite mounting evidence...

    Authors: Sham Lal, Richard Ndyomugenyi, Lucy Paintain, Neal D. Alexander, Kristian S. Hansen, Pascal Magnussen, Daniel Chandramohan and Siân E. Clarke
    Citation: Malaria Journal 2016 15:568
  31. Malaria is the main health risk for Chinese expatriates working in Niger. Health education is a recommended intervention for prevention of malaria among non-immune travellers and expatriate workers. It is urge...

    Authors: Wei Li, Le Qiang Han, Yan Jun Guo and Jing Sun
    Citation: Malaria Journal 2016 15:567
  32. Malaria remains endemic in Afghanistan. National control and prevention strategies would be greatly enhanced through a better ability to forecast future trends in disease incidence. It is, therefore, of intere...

    Authors: Mohammad Y. Anwar, Joseph A. Lewnard, Sunil Parikh and Virginia E. Pitzer
    Citation: Malaria Journal 2016 15:566
  33. Knowing the extent and spread of insecticide resistance in malaria vectors is vital to successfully manage insecticide resistance in Africa. This information in the main malaria vector, Anopheles funestus sensu s...

    Authors: Rousseau J. Djouaka, Seun M. Atoyebi, Genevieve M. Tchigossou, Jacob M. Riveron, Helen Irving, Romaric Akoton, Michael O. Kusimo, Adekunle A. Bakare and Charles S. Wondji
    Citation: Malaria Journal 2016 15:565
  34. Subsistence rice farmers in south-eastern Tanzania are often migratory, spending weeks or months tending to crops in distant fields along the river valleys and living in improvised structures known as Shamba huts...

    Authors: Johnson K. Swai, Marceline F. Finda, Edith P. Madumla, Godfrey F. Lingamba, Irene R. Moshi, Mohamed Y. Rafiq, Silas Majambere and Fredros O. Okumu
    Citation: Malaria Journal 2016 15:564
  35. Susceptibility of principal Anopheles malaria vectors to common insecticides was monitored over a 5-year period across Malawi to inform and guide the national malaria control programme.

    Authors: Themba Mzilahowa, Martin Chiumia, Rex B. Mbewe, Veronica T. Uzalili, Madalitso Luka-Banda, Anna Kutengule, Don P. Mathanga, Doreen Ali, John Chiphwanya, John Zoya, Shadreck Mulenga, Wilfred Dodoli, Jennifer Bergeson-Lockwood, Peter Troell, Jessica Oyugi, Kim Lindblade…
    Citation: Malaria Journal 2016 15:563
  36. Most patients with malaria seek treatment first in retail drug shops. Myriad studies have examined retailer behaviours and characteristics to understand the determinants to these behaviours. Geospatial methods...

    Authors: Andria Rusk, Linda Highfield, J. Michael Wilkerson, Melissa Harrell, Andrew Obala and Benjamin Amick
    Citation: Malaria Journal 2016 15:562
  37. The impact of placental malaria (PM) infection on the expression profile of some cytokines known to regulate T cell differentiation and function and their influence on birth weight remain unclear. Moreover, th...

    Authors: Jean Claude Djontu, Stalone Siewe Siewe, Yolande Delphine Mpeke Edene, Benderli Christine Nana, Edwige Vanessa Chomga Foko, Jude Daiga Bigoga, Rose F. G. Leke and Rosette Megnekou
    Citation: Malaria Journal 2016 15:561
  38. Antigenic polymorphisms are considered as one of the main strategies employed by malaria parasites to escape from the host immune responses after infections. Merozoite surface protein-1 (MSP-1) of Plasmodium viva...

    Authors: Nuno Sepúlveda, Cristiane Guimarães Morais, Luiza Carvalho Mourão, Matheus França Freire, Cor Jesus F. Fontes, Marcus Vinícius G. Lacerda, Chris J. Drakeley and Érika Martins Braga
    Citation: Malaria Journal 2016 15:559
  39. The Greater Mekong Subregion is aiming to achieve regional malaria elimination by 2030. Though a shift in malaria parasite species predominance by Plasmodium vivax has been recently documented, the transmission o...

    Authors: Peipei Li, Zhenjun Zhao, Hua Xing, Wenli Li, Xiaotong Zhu, Yaming Cao, Zhaoqing Yang, Jetsumon Sattabongkot, Guiyun Yan, Qi Fan and Liwang Cui
    Citation: Malaria Journal 2016 15:557
  40. Malaria, a parasite vector-borne disease, is one of the most significant health threats in tropical regions, despite the availability of individual chemoprophylaxis. Malaria chemoprophylaxis and chemotherapy r...

    Authors: Tiphaine Gaillard, Marylin Madamet, Francis Foguim Tsombeng, Jérôme Dormoi and Bruno Pradines
    Citation: Malaria Journal 2016 15:556
  41. The malaria burden in sub-Saharan Africa (SSA) has fallen substantially. Nevertheless, malaria remains a serious health concern, and Uganda ranks third in SSA in total malaria burden. Epidemiological studies o...

    Authors: Sergey Yegorov, Ronald M. Galiwango, Aloysious Ssemaganda, Moses Muwanga, Irene Wesonga, George Miiro, David A. Drajole, Kevin C. Kain, Noah Kiwanuka, Bernard S. Bagaya and Rupert Kaul
    Citation: Malaria Journal 2016 15:555
  42. Plasmodium infection and malaria in school children are increasingly recognized as a relevant public health problem, but data on actual prevalence and health consequences are insuffici...

    Authors: Kevin C. Sifft, Dominik Geus, Caritas Mukampunga, Jean Claude Mugisha, Felix Habarugira, Kira Fraundorfer, Claude Bayingana, Jules Ndoli, Irenee Umulisa, Corine Karema, George von Samson-Himmelstjerna, Toni Aebischer, Peter Martus, Augustin Sendegeya, Jean Bosco Gahutu and Frank P. Mockenhaupt
    Citation: Malaria Journal 2016 15:553
  43. Malaria is endemic in 13 districts of Bangladesh. A baseline malaria prevalence survey across the endemic districts of Bangladesh was conducted in 2007, when the prevalence was reported around 39.7 per 1000 po...

    Authors: Mohammad Shafiul Alam, Mohammad Moktadir Kabir, Mohammad Sharif Hossain, Shamsun Naher, Nur E. Naznin Ferdous, Wasif Ali Khan, Dinesh Mondal, Jahirul Karim, A. K. M. Shamsuzzaman, Be-Nazir Ahmed, Akramul Islam and Rashidul Haque
    Citation: Malaria Journal 2016 15:552
  44. Malaria is one of the key research concerns in climate change-health relationships. Numerous risk assessments and modelling studies provide evidence that the transmission range of malaria will expand with risi...

    Authors: Esther Achieng Onyango, Oz Sahin, Alex Awiti, Cordia Chu and Brendan Mackey
    Citation: Malaria Journal 2016 15:551
  45. Malaria, due to Plasmodium ovale, can be challenging to diagnose due to clinically mild disease and low parasite burden. Two genetically distinct sub-species of P. ovale exist: Plasmodium ovale curtisi (classic) ...

    Authors: Melissa S. Phuong, Rachel Lau, Filip Ralevski and Andrea K. Boggild
    Citation: Malaria Journal 2016 15:550

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