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  1. Rapid and correct diagnosis of malaria is considered an important strategy in the control of the disease. However, it remains to be determined how well these tests can perform in those who harbour the parasite...

    Authors: Samuel Wanji, Helen K Kimbi, Joan E Eyong, Nicholas Tendongfor and Judith L Ndamukong
    Citation: Malaria Journal 2008 7:89
  2. In Zambia the first-line treatment for uncomplicated malaria is artemisinin combination therapy (ACT), with artemether-lumefantrine currently being used. However, the antifolate regimen, sulphadoxine-pyrimetha...

    Authors: Mtawa AP Mkulama, Sandra Chishimba, Jay Sikalima, Petrica Rouse, Philip E Thuma and Sungano Mharakurwa
    Citation: Malaria Journal 2008 7:87
  3. In order to assess the effectiveness of long-lasting insecticide-treated nets (LLINs) as a method for malaria control, there is a need to determine how high is the retention of bed nets, how they are utilized,...

    Authors: Saad El-Din Hussein Hassan, Elfatih M Malik, Somia I Okoued and Elsadig M Eltayeb
    Citation: Malaria Journal 2008 7:85
  4. Plasmodium falciparum in a subset of patients can lead to cerebral malaria (CM), a major contributor to malaria-associated mortality. Despite treatment, CM mortality can be as high as 30%, while 10% of survivors ...

    Authors: Vidhan Jain, Henry B Armah, Jon E Tongren, Renée M Ned, Nana O Wilson, Sara Crawford, Pradeep K Joel, Mrigendra P Singh, Avinash C Nagpal, AP Dash, Venkatachalam Udhayakumar, Neeru Singh and Jonathan K Stiles
    Citation: Malaria Journal 2008 7:83
  5. Two Plasmodium berghei ookinete micronemal proteins, circumsporozoite and TRAP related protein (CTRP) and secreted ookinete adhesive protein (SOAP) both interact with the basal lamina component laminin. Following...

    Authors: Adéla Nacer, Ann Underhill and Hilary Hurd
    Citation: Malaria Journal 2008 7:82
  6. The relationship between malaria and obesity are largely unknown. This is partly due to the fact that malaria occurs mainly in tropical areas where, until recently, obesity was not prevalent. It now appears, h...

    Authors: Vincent Robert, Catherine Bourgouin, Delphine Depoix, Catherine Thouvenot, Marie-Noëlle Lombard and Philippe Grellier
    Citation: Malaria Journal 2008 7:81
  7. The Atelier Paludisme (Malaria Workshop) is an international training course organized by the Institut Pasteur de Madagascar, which has been held annually for the past five years. The course was designed for both...

    Authors: Olivier Domarle, Milijaona Randrianarivelojosia, Jean-Bernard Duchemin, Vincent Robert and Frédéric Ariey
    Citation: Malaria Journal 2008 7:80
  8. Intermittent preventive treatment (IPTp) is efficacious in reducing the adverse outcomes associated with pregnancy-associated malaria, however uptake of the recommended two doses is low in Tanzania, and little...

    Authors: Katherine Anders, Tanya Marchant, Pili Chambo, Pasiens Mapunda and Hugh Reyburn
    Citation: Malaria Journal 2008 7:79
  9. The emergence of drug resistance is a major problem in malaria control. For mathematical modelling of the transmission and spread of drug resistance the determinant parameters need to be identified and measure...

    Authors: Sonja Schoepflin, Jutta Marfurt, Mary Goroti, Moses Baisor, Ivo Mueller and Ingrid Felger
    Citation: Malaria Journal 2008 7:78
  10. Rainfall data have potential use for malaria prediction. However, the relationship between rainfall and the number of malaria cases is indirect and complex.

    Authors: Olivier JT Briët, Penelope Vounatsou, Dissanayake M Gunawardena, Gawrie NL Galappaththy and Priyanie H Amerasinghe
    Citation: Malaria Journal 2008 7:77
  11. Malaria in Sri Lanka is unstable and fluctuates in intensity both spatially and temporally. Although the case counts are dwindling at present, given the past history of resurgence of outbreaks despite effectiv...

    Authors: Olivier JT Briët, Penelope Vounatsou, Dissanayake M Gunawardena, Gawrie NL Galappaththy and Priyanie H Amerasinghe
    Citation: Malaria Journal 2008 7:76
  12. In the Global Strategy for Malaria Control, one of the basic elements is early detection and prompt treatment of malaria cases, especially in areas where health care facilities are inadequate. Establishing or ...

    Authors: Lalit K Das, Purushothaman Jambulingam and Candasamy Sadanandane
    Citation: Malaria Journal 2008 7:75
  13. Knock-down resistance (kdr) to DDT and pyrethroids in the major Afrotropical vector species, Anopheles gambiae sensu stricto, is associated with two alternative point mutations at amino acid position 1014 of the ...

    Authors: Federica Santolamazza, Maria Calzetta, Josiane Etang, Elena Barrese, Ibrahima Dia, Adalgisa Caccone, Martin J Donnelly, Vincenzo Petrarca, Frederic Simard, Joao Pinto and Alessandra della Torre
    Citation: Malaria Journal 2008 7:74
  14. To evaluate the cost-effectiveness of the first nationwide delivery of long-lasting insecticide-treated nets (LLITNs) as part of the 2004 measles vaccination campaign in Togo to all children between nine month...

    Authors: Dirk H Mueller, Virginia Wiseman, Dankom Bakusa, Kodjo Morgah, Aboudou Daré and Potougnima Tchamdja
    Citation: Malaria Journal 2008 7:73
  15. In order to maximize the useful therapeutic life of antimalarial drugs, it is crucial to understand the mechanisms by which parasites resistant to antimalarial drugs are selected and spread in natural populati...

    Authors: Vivian N Hawkins, Alyson Auliff, Surendra Kumar Prajapati, Kanchana Rungsihirunrat, Hapuarachchige C Hapuarachchi, Amanda Maestre, Michael T O'Neil, Qin Cheng, Hema Joshi, Kesara Na-Bangchang and Carol Hopkins Sibley
    Citation: Malaria Journal 2008 7:72
  16. The diverse physiological and pathological role of nitric oxide in innate immune defenses against many intra and extracellular pathogens, have led to the development of various methods for determining nitric o...

    Authors: Arun Sharma, Kamaraju Raghavendra, Tridibesh Adak and Aditya P Dash
    Citation: Malaria Journal 2008 7:71
  17. A simple real-time PCR assay using one set of primer and probe for rapid, sensitive and quantitative detection of Plasmodium species, with simultaneous differentiation of Plasmodium falciparum from the three othe...

    Authors: Innocent Safeukui, Pascal Millet, Sébastien Boucher, Laurence Melinard, Frédéric Fregeville, Marie-Catherine Receveur, Thierry Pistone, Pierre Fialon, Philippe Vincendeau, Hervé Fleury and Denis Malvy
    Citation: Malaria Journal 2008 7:70
  18. To evaluate the performance of a novel malaria outbreak identification system in the epidemic prone rural area of Mpumalanga Province, South Africa, for timely identification of malaria outbreaks and guiding i...

    Authors: Marlize Coleman, Michael Coleman, Aaron M Mabuza, Gerdalize Kok, Maureen Coetzee and David N Durrheim
    Citation: Malaria Journal 2008 7:69
  19. Severe malarial anaemia is a major complication of malaria infection and is multi-factorial resulting from loss of circulating red blood cells (RBCs) from parasite replication, as well as immune-mediated mecha...

    Authors: Tracey J Lamb and Jean Langhorne
    Citation: Malaria Journal 2008 7:68
  20. Aggregated haemozoin crystals within malaria-infected erythrocytes confer susceptibility of parasitized cells to a magnetic field. Here the utility of this method for diagnosis of human malaria is evaluated in...

    Authors: Stephan Karl, Makindi David, Lee Moore, Brian T Grimberg, Pascal Michon, Ivo Mueller, Maciej Zborowski and Peter A Zimmerman
    Citation: Malaria Journal 2008 7:66
  21. The work described in this article forms part of a study to suppress a population of the malaria vector Anopheles arabiensis in Northern State, Sudan, with the Sterile Insect Technique. No data have previously be...

    Authors: Michelle EH Helinski, Mo'awia M Hassan, Waleed M El-Motasim, Colin A Malcolm, Bart GJ Knols and Badria El-Sayed
    Citation: Malaria Journal 2008 7:65
  22. Daily assessment of the percentage of erythrocytes that are infected ('percent-parasitaemia') across a time-course is a necessary step in many experimental studies of malaria, but represents a time-consuming a...

    Authors: Owen Proudfoot, Nathan Drew, Anja Scholzen, Sue Xiang and Magdalena Plebanski
    Citation: Malaria Journal 2008 7:62
  23. In Papua New Guinea (PNG), combination therapy with amodiaquine (AQ) or chloroquine (CQ) plus sulphadoxine-pyrimethamine (SP) was introduced as first-line treatment against uncomplicated malaria in 2000.

    Authors: Jutta Marfurt, Ivo Müller, Albert Sie, Olive Oa, John C Reeder, Thomas A Smith, Hans-Peter Beck and Blaise Genton
    Citation: Malaria Journal 2008 7:61
  24. Insecticide-treated bed nets (ITNs) range among the most effective measures of malaria prophylaxis, yet their implementation level in sub-Saharan Africa is still low. The goal of this study was to investigate ...

    Authors: Julia N Goesch, Norbert G Schwarz, Marie-Luise Decker, Sunny Oyakhirome, Lea B Borchert, Ulrich D Kombila, Marc Poetschke, Bertrand Lell, Saadou Issifou, Peter G Kremsner and Martin P Grobusch
    Citation: Malaria Journal 2008 7:60
  25. Entomological surveys are of great importance in decision-making processes regarding malaria control strategies because they help to identify associations between vector abundance both species-specific ecology...

    Authors: Eliningaya J Kweka, Watoky MM Nkya, Aneth M Mahande, Charles Assenga, Franklin W Mosha, Ester E Lyatuu, Charles P Massenga, Edwin M Nyale, Stephen B Mwakalinga and Asanterabi Lowassa
    Citation: Malaria Journal 2008 7:59
  26. Combination therapy has become a new paradigm in malaria treatment. Amodiaquine is a common partner drug in different malaria combination therapies used or investigated in sub-Saharan Africa, but data on its e...

    Authors: Germain Mandi, Frank P Mockenhaupt, Boubacar Coulibaly, Peter Meissner and Olaf Müller
    Citation: Malaria Journal 2008 7:58
  27. The treatment options for acute Plasmodium falciparum malaria are based on the clinician classifying the patient as uncomplicated or severe according to the clinical and parasitological findings. This process is ...

    Authors: Khin Maung Lwin, Elizabeth A Ashley, Stephane Proux, Kamolrat Silamut, François Nosten and Rose McGready
    Citation: Malaria Journal 2008 7:57
  28. International travel and migration have been related with an increase of imported malaria cases. There has been considerable immigration to Barcelona from low-income countries (LIC) in recent years. The object...

    Authors: Juan Pablo Millet, Patricia Garcia de Olalla, Paloma Carrillo-Santisteve, Joaquim Gascón, Begoña Treviño, José Muñoz, Jordi Gómez i Prat, Juan Cabezos, Anna González Cordón and Joan A Caylà
    Citation: Malaria Journal 2008 7:56
  29. In order to improve the monitoring of the antimalarial drug resistance in Madagascar, a new national network based on eight sentinel sites was set up. In 2006/2007, a multi-site randomized clinical trial was d...

    Authors: Didier Ménard, Arsène Ratsimbasoa, Milijaona Randrianarivelojosia, Léon-Paul Rabarijaona, Lucie Raharimalala, Olivier Domarle, Laurence Randrianasolo, Arthur Randriamanantena, Martial Jahevitra, Valérie Andriantsoanirina, Marie-Ange Rason, Rogelin Raherinjafy, Emma Rakotomalala, Luciano Tuseo and Andrianirina Raveloson
    Citation: Malaria Journal 2008 7:55
  30. Intermittent preventive (or presumptive) treatment of infants (IPTi), the administration of a curative anti-malarial dose to infants whether or not they are known to be infected, is being considered as a new s...

    Authors: Roly D Gosling, Azra C Ghani, Jaqueline L Deen, Lorenz von Seidlein, Brian M Greenwood and Daniel Chandramohan
    Citation: Malaria Journal 2008 7:54
  31. Malaria over-diagnosis in Africa is widespread and costly both financially and in terms of morbidity and mortality from missed diagnoses. An understanding of the reasons behind malaria over-diagnosis is urgent...

    Authors: Clare IR Chandler, Caroline Jones, Gloria Boniface, Kaseem Juma, Hugh Reyburn and Christopher JM Whitty
    Citation: Malaria Journal 2008 7:53
  32. A large focus of human infections with Plasmodium knowlesi, a simian parasite naturally found in long-tailed and pig-tailed macaques was discovered in the Kapit Division of Sarawak, Malaysian Borneo. A study was ...

    Authors: Cheong H Tan, Indra Vythilingam, Asmad Matusop, Seng T Chan and Balbir Singh
    Citation: Malaria Journal 2008 7:52
  33. Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum erythrocyte membrane protein 1 f...

    Authors: Francisca Yosaatmadja, Katherine T Andrews, Michael F Duffy, Graham V Brown, James G Beeson and Stephen J Rogerson
    Citation: Malaria Journal 2008 7:51
  34. In the rural areas of sub-Saharan Africa, the majority of young children affected by malaria have no access to formal health services. Home treatment through mothers of febrile children supported by mother gro...

    Authors: Bocar Kouyaté, Florent Somé, Albrecht Jahn, Boubacar Coulibaly, Jaran Eriksen, Rainer Sauerborn, Lars Gustafsson, Göran Tomson, Heiko Becher and Olaf Mueller
    Citation: Malaria Journal 2008 7:50
  35. In order to evaluate whether criteria for LLIN field performance (phase III) set by the WHO Pesticide Evaluation Scheme are met, first and second generations of one of these products, PermaNet®, a polyester net u...

    Authors: Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon and Chi Phan
    Citation: Malaria Journal 2008 7:49
  36. Sulphadoxine-pyrimethamine has been abandoned as first- or second-line treatment by most African malaria endemic countries in favour of artemisinin-based combination treatments, but the drug is still used as i...

    Authors: Petra F Mens, Chantal van Overmeir, Maryline Bonnet, Jean-Claude Dujardin and Umberto d'Alessandro
    Citation: Malaria Journal 2008 7:48
  37. The transcriptional regulation of Plasmodium during its complex life cycle requires sequential activation and/or repression of different genetic programmes. MicroRNAs (miRNAs) are a highly conserved class of non-...

    Authors: Xiangyang Xue, Qingfeng Zhang, Yufu Huang, Le Feng and Weiqing Pan
    Citation: Malaria Journal 2008 7:47
  38. Segmental duplications (SD) have been found in genomes of various organisms, often accumulated at the ends of chromosomes. It has been assumed that the sequence homology in-between the SDs allow for ectopic in...

    Authors: Bobo W Mok, Ulf Ribacke, Ellen Sherwood and Mats Wahlgren
    Citation: Malaria Journal 2008 7:46
  39. Parasite concentration methods facilitate molecular, biochemical and immunological research on the erythrocytic stages of Plasmodium. In this paper, an adaptation of magnetic MACS® columns for the purification of...

    Authors: Clotilde Ribaut, Antoine Berry, Séverine Chevalley, Karine Reybier, Isabelle Morlais, Daniel Parzy, Françoise Nepveu, Françoise Benoit-Vical and Alexis Valentin
    Citation: Malaria Journal 2008 7:45
  40. To reduce the intolerable burden of malaria in pregnancy, the Ministry of Health in Uganda improved the antenatal care package by including a strong commitment to increase distribution of insecticide-treated n...

    Authors: Mpungu S Kiwuwa and Patrobas Mufubenga
    Citation: Malaria Journal 2008 7:44
  41. Studies were conducted between April 2004 and February 2006 to determine the blood-feeding pattern of Anopheles mosquitoes in Mwea Kenya.

    Authors: Simon M Muriu, Ephantus J Muturi, Josephat I Shililu, Charles M Mbogo, Joseph M Mwangangi, Benjamin G Jacob, Lucy W Irungu, Richard W Mukabana, John I Githure and Robert J Novak
    Citation: Malaria Journal 2008 7:43
  42. In Plasmodium falciparum-infected children, the relationships between blood cell histopathology, blood plasma components, development of immunocompetence and disease severity remain poorly understood. Blood from ...

    Authors: Virginia S Baker, Godwin E Imade, Norman B Molta, Pallavi Tawde, Sunday D Pam, Michael O Obadofin, Soloman A Sagay, Daniel Z Egah, Daniel Iya, Bangmboye B Afolabi, Murray Baker, Karen Ford, Robert Ford, Kenneth H Roux and Thomas CS Keller III
    Citation: Malaria Journal 2008 7:41
  43. Transmission of Plasmodium falciparum generally decreases with increasing elevation, in part because lower temperature slows the development of both parasites and mosquitoes. However, other aspects of the terrain...

    Authors: Justin M Cohen, Kacey C Ernst, Kim A Lindblade, John M Vulule, Chandy C John and Mark L Wilson
    Citation: Malaria Journal 2008 7:40
  44. Urban malaria is likely to become increasingly important as a consequence of the growing proportion of Africans living in cities. A novel sampling strategy was developed for urban areas to generate a sample si...

    Authors: Jose G Siri, Kim A Lindblade, Daniel H Rosen, Bernard Onyango, John M Vulule, Laurence Slutsker and Mark L Wilson
    Citation: Malaria Journal 2008 7:39

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