WHO. World Malaria Report: 20 years of global progress and challenges. Geneva: World Health Organization; 2020.
Google Scholar
Programme Nationale de Lutte contre le Paludisme. Plan Stratégique de Lutte contre le Paludisme—Madagascar 2013–2017. Antananarivo: Programme Nationale de Lutte contre le Paludisme; 2012.
Google Scholar
Howes RE, Mioramalala SA, Ramiranirina B, Franchard T, Rakotorahalahy AJ, Bisanzio D, et al. Contemporary epidemiological overview of malaria in Madagascar: operational utility of reported routine case data for malaria control planning. Malar J. 2016;15:502.
Article
PubMed
PubMed Central
Google Scholar
Ihantamalala FA, Rakotoarimanana FMJ, Ramiadantsoa T, Rakotondramanga JM, Pennober G, Rakotomanana F, et al. Spatial and temporal dynamics of malaria in Madagascar. Malar J. 2018;17:58.
Article
PubMed
PubMed Central
Google Scholar
Direction de Lutte contre le Paludisme. Plan Stratégique de Lutte contre le Paludisme—Madagascar 2018–2022. Antananarivo: Direction de Lutte contre le Paludisme; 2017.
Google Scholar
Lindblade KA, Steinhardt L, Samuels A, Kachur SP, Slutsker L. The silent threat: asymptomatic parasitemia and malaria transmission. Expert Rev Anti Infect Ther. 2013;11:623–39.
Article
CAS
PubMed
Google Scholar
Lin JT, Saunders DL, Meshnick SR. The role of submicroscopic parasitemia in malaria transmission: what is the evidence? Trends Parasitol. 2014;30:183–90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Andolina C, Rek JC, Briggs J, Okoth J, Musiime A, Ramjith J, et al. Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study. Lancet Infect Dis. 2021;21:1568–78.
Article
PubMed
PubMed Central
Google Scholar
King CL, Davies DH, Felgner P, Baum E, Jain A, Randall A, et al. Biosignatures of exposure/transmission and immunity. Am J Trop Med Hyg. 2015;93:16–27.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ashton RA, Kefyalew T, Rand A, Sime H, Asefa A, Makasha A, et al. Geostatistical modeling of malaria endemicity using serological indicators of exposure collected through school surveys. Am J Trop Med Hyg. 2015;93:168–77.
Article
PubMed
PubMed Central
Google Scholar
Steinhardt LC, Ravaoarisoa E, Wiegand R, Harimanana A, Hedje J, Cotte AH, et al. School-based serosurveys to assess the validity of using routine health facility data to target malaria interventions in the Central Highlands of Madagascar. J Infect Dis. 2021;223:995–1004.
Article
PubMed
Google Scholar
Tongren JE, Drakeley CJ, McDonald SLR, Reyburn HG, Manjurano A, Nkya WM, et al. Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malaria. Infect Immun. 2006;74:257–64.
Article
CAS
PubMed
PubMed Central
Google Scholar
Akpogheneta OJ, Duah NO, Tetteh KKA, Dunyo S, Lanar DE, Pinder M, et al. Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific. Infect Immun. 2008;76:1748–55.
Article
CAS
PubMed
PubMed Central
Google Scholar
Stanisic DI, Fowkes FJI, Koinari M, Javati S, Lin E, Kiniboro B, et al. Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response. Infect Immun. 2015;83:646–60.
Article
PubMed
PubMed Central
CAS
Google Scholar
Kangoye DT, Noor A, Midega J, Mwongeli J, Mkabili D, Mogeni P, et al. Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan Coast. Malar J. 2016;15:213.
Article
PubMed
PubMed Central
CAS
Google Scholar
Yman V, White MT, Rono J, Arcà B, Osier FH, Troye-Blomberg M, et al. Antibody acquisition models: a new tool for serological surveillance of malaria transmission intensity. Sci Rep. 2016;6:19472.
Article
CAS
PubMed
PubMed Central
Google Scholar
Assefa A, Ali Ahmed A, Deressa W, Sime H, Mohammed H, Kebede A, et al. Multiplex serology demonstrate cumulative prevalence and spatial distribution of malaria in Ethiopia. Malar J. 2019;18:246.
Article
PubMed
PubMed Central
CAS
Google Scholar
Amratia P, Psychas P, Abuaku B, Ahorlu C, Millar J, Oppong S, et al. Characterizing local-scale heterogeneity of malaria risk: a case study in Bunkpurugu-Yunyoo district in northern Ghana. Malar J. 2019;18:81.
Article
PubMed
PubMed Central
Google Scholar
Institut National de la Statistique (INSTAT) et ICF Macro. Enquête Démographique et de Santé de Madagascar 2008–2009. Antananarivo: Institut National de la Statistique; 2010.
Google Scholar
Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, et al. Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections. Malar J. 2014;13:53.
Article
PubMed
PubMed Central
Google Scholar
WHO for Africa. Implementation of indoor residual spraying of insecticides for malaria control in the WHO African Region Report. Kinshasha: World Health Organization; 2007.
Google Scholar
Institut National de la Statistique (INSTAT), PNLP Madagascar, Institut Pasteur de Madagascar. Malaria Indicator Survey 2013. Calverton: INSTAT, PNLP, IPM et ICF International; 2013.
Google Scholar
Okell LC, Ghani AC, Lyons E, Drakeley CJ. Submicroscopic infection in Plasmodium falciparum—endemic populations: a systematic review and meta-analysis. J Infect Dis. 2009;200:1509–17.
Article
PubMed
Google Scholar
Okell LC, Bousema T, Griffin JT, Ouédraogo AL, Ghani AC, Drakeley CJ. Factors determining the occurrence of submicroscopic malaria infections and their relevance for control. Nat Commun. 2012;3:1237.
Article
PubMed
CAS
Google Scholar
Wu L, Van Den Hoogen LL, Slater H, Walker PGT, Ghani AC, Drakeley CJ, Okell LC. Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies. Nature. 2015;528:S86–93.
Article
PubMed
Google Scholar
Arambepola R, Keddie SH, Collins EL, Twohig KA, Bertozzi-Villa A, Chestnutt EG, et al. Spatiotemporal mapping of malaria prevalence in Madagascar using routine surveillance and health survey data. Sci Rep. 2020;10:18129.
Article
CAS
PubMed
PubMed Central
Google Scholar
Maina J, Ouma PO, Macharia PM, Alegana VA, Mitto B, Fall IS, et al. A spatial database of health facilities managed by the public health sector in sub Saharan Africa. Sci Data. 2019;6:134.
Article
PubMed
PubMed Central
CAS
Google Scholar
Stewart L, Gosling R, Griffin J, Gesase S, Campo J, Hashim R, et al. Rapid assessment of malaria transmission using age-specific sero-conversion rates. PLoS ONE. 2009;4: e6083.
Article
PubMed
PubMed Central
CAS
Google Scholar
Okebe J, Affara M, Correa S, Muhammad AK, Nwakanma D, Drakeley C, et al. School-based countrywide seroprevalence survey reveals spatial heterogeneity in malaria transmission in the Gambia. PLoS ONE. 2014;9: e110926.
Article
PubMed
PubMed Central
CAS
Google Scholar
Perraut R, Richard V, Varela M-L, Trape J-F, Guillotte M, Tall A, et al. Comparative analysis of IgG responses to Plasmodium falciparum MSP1p19 and PF13-DBL1α1 using ELISA and a magnetic bead-based duplex assay (MAGPIX®-Luminex) in a Senegalese meso-endemic community. Malar J. 2014;13:410.
Article
PubMed
PubMed Central
Google Scholar
Kerkhof K, Canier L, Kim S, Heng S, Sochantha T, Sovannaroth S, et al. Implementation and application of a multiplex assay to detect malaria-specific antibodies: a promising tool for assessing malaria transmission in Southeast Asian pre-elimination areas. Malar J. 2015;14:338.
Article
PubMed
PubMed Central
CAS
Google Scholar
Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC). MODIS and VIIRS Land Product RESTful Web Service. Oak Ridge: Oak Ridge National Laboratory Distributed Active Archive Center; 2018. https://doi.org/10.3334/ORNLDAAC/1600
Book
Google Scholar
Kang SY, Battle KE, Gibson HS, Ratsimbasoa A, Randrianarivelojosia M, Ramboarina S, et al. Spatio-temporal mapping of Madagascar’s Malaria Indicator Survey results to assess Plasmodium falciparum endemicity trends between 2011 and 2016. BMC Med. 2018;16:71.
Article
PubMed
PubMed Central
Google Scholar
Friedl MA, Sulla-Menashe D, Tan B, Schneider A, Ramankutty N, Sibley A, et al. MODIS Collection 5 global land cover: algorithm refinements and characterization of new datasets. Remote Sens Environ. 2010;114:168–82.
Article
Google Scholar
Farr TG, Rosen PA, Caro E, Crippen R, Duren R, Hensley S, et al. The shuttle radar topography mission. Rev Geophys. 2007;45:2004.
Article
Google Scholar
Loveland TR, Belward AS. The international geosphere biosphere programme data and information system global land cover data set (DIScover). Acta Astronaut. 1997;41:681–9.
Article
Google Scholar
R Core Team. R: a language and environment for statistical computing. Vienna: R Core Team; 2020.
Google Scholar
Bivand RS, Wong DWS. Comparing implementations of global and local indicators of spatial association. TEST. 2018;27:716–48.
Article
Google Scholar
Bivand RS, Pebesma E, Gómez-Rubio V. Applied spatial data analysis with R. 2nd ed. New York: Springer; 2018. https://doi.org/10.1007/978-1-4614-7618-4.
Book
Google Scholar
Anselin L. Local indicators of spatial association-LISA. Geogr Anal. 2010;27:93–115.
Article
Google Scholar
Getis A, Ord JK. The analysis of spatial association by use of distance statistics. Geogr Anal. 1992;24:189–206.
Article
Google Scholar
Mauny F, Viel JF, Handschumacher P, Sellin B. Multilevel modelling and malaria: a new method for an old disease. Int J Epidemiol. 2004;33:1337–44.
Article
CAS
PubMed
Google Scholar
Harrison XA. A comparison of observation-level randomeffect and Beta-Binomial models for modelling overdispersion in Binomial data in ecology & evolution. PeerJ. 2015;2015: e1114.
Article
Google Scholar
Bartoń K. MuMIn: Multi-model inference, software. 2020. https://cran.r-project.org/package=MuMIn. Accessed 01 Mar 2022.
Burnham KP, Anderson DR. Model selection and multimodel inference. 2nd ed. New York: Springer; 2004. https://doi.org/10.1007/b97636.
Book
Google Scholar
Nakagawa S, Schielzeth H. A general and simple method for obtaining R2 from generalized linear mixed-effects models. Methods Ecol Evol. 2013;4:133–42.
Article
Google Scholar
Bates D, Mächler M, Bolker BM, Walker SC. Fitting linear mixed-effects models using lme4. J Stat Softw. 2015;67: i01.
Article
Google Scholar
Rosado J, White MT, Longley RJ, Lacerda M, Monteiro W, Brewster J, et al. Heterogeneity in response to serological exposure markers of recent Plasmodium vivax infections in contrasting epidemiological contexts. PLoS Negl Trop Dis. 2021;15: e0009165.
Article
PubMed
PubMed Central
Google Scholar
WHO. World Malaria Report 2021. Geneva: World Health Organization; 2021.
Google Scholar
Razakandrainibe R, Thonier V, Ratsimbasoa A, Rakotomalala E, Ravaoarisoa E, Raherinjafy R, et al. Epidemiological situation of malaria in Madagascar: baseline data for monitoring the impact of malaria control programmes using serological markers. Acta Trop. 2009;111:160–7.
Article
PubMed
Google Scholar
Bousema T, Okell L, Felger I, Drakeley C. Asymptomatic malaria infections: detectability, transmissibility and public health relevance. Nat Rev Microbiol. 2014;12:833–40.
Article
CAS
PubMed
Google Scholar
Ihantamalala FA, Bonds MH, Randriamihaja M, Rakotonirina L, Herbreteau V, Révillion C, et al. Geographic barriers to establishing a successful hospital referral system in rural Madagascar. BMJ Glob Health. 2021;6: e007145.
Article
PubMed
PubMed Central
Google Scholar
Garchitorena A, Ihantamalala FA, Révillion C, Cordier LF, Randriamihaja M, Razafinjato B, et al. Geographic barriers to achieving universal health coverage: evidence from rural Madagascar. Health Policy Plan. 2021;36:1659–70.
Article
PubMed
PubMed Central
Google Scholar
WHO. Guideline on health policy and system support to optimize community health worker selected highlights. Geneva: World Health Organization; 2012.
Google Scholar
U. S. President’s Malaria Initiative Madagascar. Malaria Operational Plan FY 2020. Pennsylvania: PMI; 2020.
Google Scholar
Manjurano A, Okell L, Lukindo T, Reyburn H, Olomi R, Roper C, et al. Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania. Malar J. 2011;10:370.
Article
PubMed
PubMed Central
Google Scholar
Weiss DJ, Mappin B, Dalrymple U, Bhatt S, Cameron E, Hay SI, et al. Re-examining environmental correlates of Plasmodium falciparum malaria endemicity: a data-intensive variable selection approach. Malar J. 2015;14:68.
Article
PubMed
PubMed Central
Google Scholar
Guerra CA, Snow RW, Hay SI. Mapping the global extent of malaria in 2005. Trends Parasitol. 2006;22:353–8.
Article
PubMed
PubMed Central
Google Scholar
Paaijmans KP, Thomas MB. The influence of mosquito resting behaviour and associated microclimate for malaria risk. Malar J. 2011;10:183.
Article
PubMed
PubMed Central
Google Scholar
Abiodun GJ, Maharaj R, Witbooi P, Okosun KO. Modelling the influence of temperature and rainfall on the population dynamics of Anopheles arabiensis. Malar J. 2016;15:364.
Article
PubMed
PubMed Central
Google Scholar
Korenromp EL, Miller J, Cibulskis RE, Cham MK, Alnwick D. Dye. Monitoring mosquito net coverage for malaria control in Africa: possession vs. use by children under 5 years. Trop Med Int Health. 2003;8:693–703.
Article
PubMed
Google Scholar
Bernard J, Mtove G, Mandike R, Mtei F, Maxwell C, Reyburn H. Equity and coverage of insecticide-treated bed nets in an area of intense transmission of Plasmodium falciparum in Tanzania. Malar J. 2009;8:65.
Article
PubMed
PubMed Central
Google Scholar
Kulkarni MA, Vanden Eng J, Desrochers RE, Hoppe Cotte A, Goodson JL, Johnston A, et al. Contribution of integrated campaign distribution of long-lasting insecticidal nets to coverage of target groups and total populations in malaria-endemic areas in Madagascar. Am J Trop Med Hyg. 2010;82:420–5.
Article
PubMed
PubMed Central
Google Scholar
Braimah N, Drakeley C, Kweka E, Mosha F, Helinski M, Pates H, Maxwell C, Massawe T, Kenward MG, Curtis C. Tests of bednet traps (Mbita traps) for monitoring mosquito populations and time of biting in Tanzania and possible impact of prolonged insecticide treated net use. Int J Trop Insect Sci. 2005;25:208–13.
Article
Google Scholar
Moiroux N, Gomez MB, Pennetier C, Elanga E, Djènontin A, Chandre F, et al. Changes in Anopheles funestus biting behavior following universal coverage of long-lasting insecticidal nets in Benin. J Infect Dis. 2010;206:1622–9.
Article
CAS
Google Scholar
Tantely ML, Rakotoniaina JC, Tata E, Andrianaivolambo L, Fontenille D, Elissa N. Modification of Anopheles gambiae distribution at high altitudes in Madagascar. J Vector Ecol. 2012;37:402–6.
Article
PubMed
Google Scholar
Bousema T, Griffin JT, Sauerwein RW, Smith DL, Churcher TS, Takken W, et al. Hitting hotspots: spatial targeting of malaria for control and elimination. PLoS Med. 2012;9: e1001165.
Article
PubMed
PubMed Central
Google Scholar
The malERA Refresh Consultative Panel on Characterising the Reservoir and Measuring Transmission. malERA: an updated research agenda for characterising the reservoir and measuring transmission in malaria elimination and eradication. PLoS Med. 2012;14: e1002452.
Article
Google Scholar