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  1. The Cascades region, Burkina Faso, has a high malaria burden despite reported high insecticide-treated mosquito net (ITN) use. Human and vector activities outside the hours when indoor interventions offer dire...

    Authors: Federica Guglielmo, Antoine Sanou, Thomas Churcher, Heather M. Ferguson, Hilary Ranson and Ellie Sherrard-Smith

    Citation: Malaria Journal 2021 20:44

    Content type: Research

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  2. In the absence of a method to culture Plasmodium vivax, the only way to source parasites is ex vivo. This hampers many aspects of P. vivax research. This study aimed to assess the safety of apheresis, a method fo...

    Authors: Anand Odedra, Kari Mudie, Glen Kennedy, Rebecca E. Watts, Emilie Rossignol, Hayley Mitchell, Jeremy Gower, Maria Rebelo, Zuleima Pava, Rebecca Pawliw, Stephen Woolley, David G. Lalloo, Greg Robinson, Sean Lynch, Katharine A. Collins, Fiona Amante…

    Citation: Malaria Journal 2021 20:43

    Content type: Research

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  3. Malaria surveillance is critical for monitoring changes in malaria morbidity over time. National Malaria Control Programmes often rely on surrogate measures of malaria incidence, including the test positivity ...

    Authors: Jaffer Okiring, Adrienne Epstein, Jane F. Namuganga, Victor Kamya, Asadu Sserwanga, James Kapisi, Chris Ebong, Simon P. Kigozi, Arthur Mpimbaza, Humphrey Wanzira, Jessica Briggs, Moses R. Kamya, Joaniter I. Nankabirwa and Grant Dorsey

    Citation: Malaria Journal 2021 20:42

    Content type: Research

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  4. School-based behaviour change communication interventions could help to achieve behavioural changes in the school and enhance the enrollment of the students and teachers as health messengers to local communiti...

    Authors: Fira Abamecha, Morankar Sudhakar, Lakew Abebe, Yohannes Kebede, Guda Alemayehu and Zewdie Birhanu

    Citation: Malaria Journal 2021 20:41

    Content type: Research

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  5. Malaria remains a major public health problem in South America, mostly in the Amazon region. Among newly proposed ways of controlling malaria transmission to humans, paratransgenesis is a promising alternative...

    Authors: Elerson Matos Rocha, Osvaldo Marinotti, Deidre Machado Serrão, Laura Viana Correa, Ricardo de Melo Katak, Campos-de-Oliveir Juan, Veranilce Alves Muniz, Marta Rodrigues de Oliveira, Joaquim Ferreira, Marcos Cézar Fernandes Pessoa, Rosemary Aparecida Roque, Adolfo Jose da Mota, Piero Onorati, Jayme A. Souza-Neto, Olle Terenius and Wanderli Pedro Tadei

    Citation: Malaria Journal 2021 20:40

    Content type: Research

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  6. The World Health Organization recommends confirmatory diagnosis by microscopy or malaria rapid diagnostic test (RDT) in patients with suspected malaria. In recent years, mobile medical applications (MMAs), whi...

    Authors: Theodoor Visser, Sumedh Ramachandra, Emilie Pothin, Jan Jacobs, Jane Cunningham, Arnaud Le Menach, Michelle L. Gatton, Samaly dos Santos Souza, Sydney Nelson, Luke Rooney and Michael Aidoo

    Citation: Malaria Journal 2021 20:39

    Content type: Research

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  7. Characterizing the genetic diversity of malaria parasite populations in different endemic settings (from low to high) could be helpful in determining the effectiveness of malaria interventions. This study comp...

    Authors: Mary A. Oboh, Tolla Ndiaye, Khadim Diongue, Yaye D. Ndiaye, Mouhamad Sy, Awa B. Deme, Mamadou A. Diallo, Mamadou S. Yade, Sarah K. Volkman, Aida S. Badiane, Alfred Amambua-Ngwa and Daouda Ndiaye

    Citation: Malaria Journal 2021 20:38

    Content type: Research

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  8. Plasmodium falciparum, the parasite causing malaria, affects populations in many endemic countries threatening mainly individuals with low malaria immunity, especially children. Despite the approval of the first ...

    Authors: Melanie Seidel-Greven, Otchere Addai-Mensah, Holger Spiegel, Gwladys Nina Chiegoua Dipah, Stefan Schmitz, Gudrun Breuer, Margaret Frempong, Andreas Reimann, Torsten Klockenbring, Rainer Fischer, Stefan Barth and Rolf Fendel

    Citation: Malaria Journal 2021 20:37

    Content type: Research

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  9. Many countries, including Rwanda, have mosquito monitoring programmes in place to support decision making in the fight against malaria. However, these programmes can be costly, and require technical (entomolog...

    Authors: Marilyn Milumbu Murindahabi, Willem Takken, Xavier Misago, Elias Niyituma, Jackie Umupfasoni, Emmanuel Hakizimana, Arnold J. H. van Vliet, P. Marijn Poortvliet, Leon Mutesa, Nathalie Kayiramirwa Murindahabi and Constantianus J. M. Koenraadt

    Citation: Malaria Journal 2021 20:36

    Content type: Research

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  10. The sequestration of Plasmodium falciparum infected cells in the placenta results in placental malaria (PM). It activates the mother's immune cells and induces secretion of inflammatory cytokines, which might inf...

    Authors: Samia Omer, Clara Franco-Jarava, Ali Noureldien, Mona Omer, Mutasim Abdelrahim, Israel Molina and Ishag Adam

    Citation: Malaria Journal 2021 20:35

    Content type: Research

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  11. Malaria control in sub-Saharan Africa relies upon prompt case management with artemisinin-based combination therapy (ACT). Ring-stage parasite mRNA, measured by sbp1 quantitative reverse-transcriptase PCR (qRT-PC...

    Authors: Almahamoudou Mahamar, Kjerstin Lanke, Wouter Graumans, Halimatou Diawara, Koualy Sanogo, Kalifa Diarra, Sidi Mohamed Niambele, Roly Gosling, Chris Drakeley, Ingrid Chen, Alassane Dicko, Teun Bousema and Michelle E. Roh

    Citation: Malaria Journal 2021 20:34

    Content type: Research

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  12. Anopheles species identification is essential for an effective malaria vector control programme. Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) has been developed to...

    Authors: Cécile Nabet, Abdoulaye K. Kone, Abdoulaye K. Dia, Moussa Sylla, Magali Gautier, Mohammed Yattara, Mahamadou A. Thera, Ousmane Faye, Leo Braack, Sylvie Manguin, Abdoul H. Beavogui, Ogobara Doumbo, Frédérick Gay and Renaud Piarroux

    Citation: Malaria Journal 2021 20:33

    Content type: Research

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  13. Malaria remains highly endemic in Cameroon. The rapid emergence and spread of drug resistance was responsible for the change from monotherapies to artemisinin-based combinations. This systematic review and met...

    Authors: Peter Thelma Ngwa Niba, Akindeh M. Nji, Marie-Solange Evehe, Innocent M. Ali, Palmer Masumbe Netongo, Randolph Ngwafor, Marcel N. Moyeh, Lesley Ngum Ngum, Oliva Ebie Ndum, Fon Abongwa Acho, Cyrille Mbanwi Mbu’u, Dorothy A. Fosah, Barbara Atogho-Tiedeu, Olivia Achonduh-Atijegbe, Rosine Djokam-Dadjeu, Jean Paul Kengne Chedjou…

    Citation: Malaria Journal 2021 20:32

    Content type: Research

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  14. Multi-genotype malaria infections are frequent in endemic area, and people commonly harbour several genetically distinct Plasmodium falciparum variants. The influence of genetic multiplicity and whether some spec...

    Authors: Paul Sondo, Biebo Bihoun, Marc Christian Tahita, Karim Derra, Toussaint Rouamba, Seydou Nakanabo Diallo, Adama Kazienga, Hamidou Ilboudo, Innocent Valea, Zekiba Tarnagda, Hermann Sorgho, Thierry Lefèvre and Halidou Tinto

    Citation: Malaria Journal 2021 20:31

    Content type: Research

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  15. The prevalence and genotypes of G6PD deficiency vary worldwide, with higher prevalence in malaria endemic areas. The first-time assessment of G6PD deficiency prevalence and molecular characterization of G6PD muta...

    Authors: Amkha Sanephonasa, Chalisa Louicharoen Cheepsunthorn, Naly Khaminsou, Onekham Savongsy, Issarang Nuchprayoon and Kamonlak Leecharoenkiat

    Citation: Malaria Journal 2021 20:30

    Content type: Research

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  16. Attempts have been made to link procurement of long-lasting insecticidal nets (LLIN) not only to the price but also the expected performance of the product. However, to date it has not been possible to identif...

    Authors: Albert Kilian, Emmanuel Obi, Paul Mansiangi, Ana Paula Abílio, Khamis Ameir Haji, Estelle Guillemois, Vera Chetty, Amy Wheldrake, Sean Blaufuss, Bolanje Olapeju, Stella Babalola, Stephen J. Russell and Hannah Koenker

    Citation: Malaria Journal 2021 20:29

    Content type: Research

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  17. Impaired autonomic control of postural homeostasis resulting in orthostatic hypotension has been described in falciparum malaria. However, severe orthostatic intolerance in Plasmodium vivax has been rarely report...

    Authors: Chaisith Sivakorn, Polrat Wilairatana, Srivicha Krudsood, Marcus J. Schultz, Tachpon Techarang, Khanittha Kheawsawaung and Arjen M. Dondorp

    Citation: Malaria Journal 2021 20:28

    Content type: Case report

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  18. The Malaria Elimination Demonstration Project (MEDP) maintained a workforce of 235 Village Malaria Workers (VMWs) and 25 Malaria Field Coordinators (MFCs) to conduct disease surveillance, case management, IEC/...

    Authors: Harsh Rajvanshi, Sekh Nisar, Praveen K. Bharti, Himanshu Jayswar, Ashok K. Mishra, Ravendra K. Sharma, Kalyan B. Saha, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal

    Citation: Malaria Journal 2021 20:27

    Content type: Research

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  19. Physical durability of long-lasting-insecticidal nets (LLIN) is an important aspect of the effectiveness of LLIN as a malaria prevention tool, but there is limited data on performance across locations and prod...

    Authors: Albert Kilian, Emmanuel Obi, Paul Mansiangi, Ana Paula Abílio, Khamis Ameir Haji, Sean Blaufuss, Bolanle Olapeju, Stella Babalola and Hannah Koenker

    Citation: Malaria Journal 2021 20:26

    Content type: Research

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  20. Malaria is a top cause of mortality on the island nation of Madagascar, where many rural communities rely on subsistence agriculture and livestock production. Understanding feeding behaviours of Anopheles in this...

    Authors: Micaela Finney, Benjamin A. McKenzie, Bernadette Rabaovola, Alice Sutcliffe, Ellen Dotson and Sarah Zohdy

    Citation: Malaria Journal 2021 20:25

    Content type: Research

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  21. More than 200 million people live in areas of highly seasonal malaria transmission where Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) was recommended in 2012 ...

    Authors: Almahamoudou Mahamar, Djibrilla Issiaka, Ahamadou Youssouf, Sidi M. Niambele, Harouna M. Soumare, Oumar Attaher, Amadou Barry, David L. Narum, Patrick E. Duffy, Brian Greenwood, Michal Fried and Alassane Dicko

    Citation: Malaria Journal 2021 20:23

    Content type: Research

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  22. There is an increasing need for finer spatial resolution data on malaria risk to provide micro-stratification to guide sub-national strategic plans. Here, spatial-statistical techniques are used to exploit rou...

    Authors: Victor A. Alegana, Laurissa Suiyanka, Peter M. Macharia, Grace Ikahu-Muchangi and Robert W. Snow

    Citation: Malaria Journal 2021 20:22

    Content type: Research

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  23. In 2018, an estimated 228 million cases of malaria occurred worldwide. Countries are far from having achieved reasonable levels of national protocol compliance among health workers. Lack of awareness of treatm...

    Authors: Marta Blanco, Pablo Suárez-Sanchez, Belén García, Jesús Nzang, Policarpo Ncogo, Matilde Riloha, Pedro Berzosa, Agustín Benito and María Romay-Barja

    Citation: Malaria Journal 2021 20:21

    Content type: Research

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  24. The COVID-19 pandemic has resulted in massive global disruptions with considerable impact on the delivery of health services and national health programmes. Since the detection of the first COVID-19 case on 5t...

    Authors: Kinley Penjor, Tobgyal, Tandin Zangpo, Archie C. A. Clements, Darren J. Gray and Kinley Wangdi

    Citation: Malaria Journal 2021 20:20

    Content type: Commentary

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  25. Malaria volunteers have contributed significantly to malaria control achieving a reduction of annual parasite incidence to pre-elimination levels in several townships across Myanmar. However, the volunteers’ r...

    Authors: Win Han Oo, Elizabeth Hoban, Lisa Gold, Kyu Kyu Than, Thazin La, Aung Thi and Freya J. I. Fowkes

    Citation: Malaria Journal 2021 20:19

    Content type: Research

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  26. Accurate measurement of anti-malarial drug concentrations in therapeutic efficacy studies is essential to distinguish between inadequate drug exposure and anti-malarial drug resistance, and to inform optimal a...

    Authors: Thomas A. Anyorigiya, Sandra Castel, Katya Mauff, Frank Atuguba, Bernhards Ogutu, Abraham Oduro, David Dosoo, Kwaku-Poku Asante, Seth Owusu-Agyei, Alexander Dodoo, Abraham Hodgson, Fred Binka, Lesley J. Workman, Elizabeth N. Allen, Paolo Denti, Lubbe Wiesner…

    Citation: Malaria Journal 2021 20:18

    Content type: Research

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  27. Elevated angiopoietin-2 (Angpt-2) concentrations are associated with worse overall neurocognitive function in severe malaria survivors, but the specific domains affected have not been elucidated.

    Authors: Benson J. Ouma, Paul Bangirana, John M. Ssenkusu, Dibyadyuti Datta, Robert O. Opoka, Richard Idro, Kevin C. Kain, Chandy C. John and Andrea L. Conroy

    Citation: Malaria Journal 2021 20:17

    Content type: Research

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  28. The emergence and spread of anti-malarial resistance continues to hinder malaria control. Plasmodium falciparum, the species that causes most human malaria cases and most deaths, has shown resistance to almost al...

    Authors: Ana Alvarez-Fernandez, María J. Bernal, Isabel Fradejas, Alexandra Martin Ramírez, Noor Azian Md Yusuf, Marta Lanza, Shamilah Hisam, Ana Pérez de Ayala and José M. Rubio

    Citation: Malaria Journal 2021 20:16

    Content type: Research

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  29. Although autochthonous malaria cases are no longer reported in Anhui Province, China, imported malaria has become a major health concern. The proportion of reported malaria cases caused by Plasmodium ovale spp. i...

    Authors: Tao Zhang, Shuqi Wang, Duoquan Wang, Sarah Auburn, Shenning Lu, Xian Xu, Jingjing Jiang, Xiaofeng Lyu, Chen Yu, Cuicui Tian, Shizhu Li and Weidong Li

    Citation: Malaria Journal 2021 20:15

    Content type: Research

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  30. Microscopy and rapid diagnostic tests (RDTs) are the main techniques used to diagnose malaria. While microscopy is considered the gold standard, RDTs have established popularity as they allow for rapid diagnos...

    Authors: Nobert Mudare, Zvifadzo Matsena-Zingoni, Aramu Makuwaza, Edmore Mamini, Shungu S. Munyati, Lovemore Gwanzura, Nicholas Midzi, Susan L. Mutambu, Peter Mason, Tamaki Kobayashi and Sungano Mharakurwa

    Citation: Malaria Journal 2021 20:14

    Content type: Research

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  31. Malaria and HIV are two important public health issues. However, evidence on HIV-Plasmodium vivax co-infection (HIV/PvCo) is scarce, with most of the available information related to Plasmodium falciparum on the ...

    Authors: Paola López Del-Tejo, Nadia Cubas-Vega, Cecilia Caraballo-Guerra, Bernardo Maia da Silva, Jefferson da Silva Valente, Vanderson Souza Sampaio, Djane Clarys Baia-da-Silva, Daniel Barros Castro, Flor Ernestina Martinez-Espinosa, André Machado Siqueira, Marcus Vinícius Guimarães Lacerda, Wuelton Marcelo Monteiro and Fernando Val

    Citation: Malaria Journal 2021 20:13

    Content type: Research

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  32. N,N-Diethyl-3-methylbenzamide (DEET) topical mosquito repellents are effective personal protection tools. However, DEET-based repellents tend to have low consumer acceptability because they are cosmetically unapp...

    Authors: Emmanuel Mbuba, Olukayode G. Odufuwa, Frank C. Tenywa, Rose Philipo, Mgeni M. Tambwe, Johnson K. Swai, Jason D. Moore and Sarah J. Moore

    Citation: Malaria Journal 2021 20:12

    Content type: Research

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  33. The invasion of the mosquito salivary glands by Plasmodium sporozoites is a critical step that defines the success of malaria transmission and a detailed understanding of the molecules responsible for salivary gl...

    Authors: Bianca B. Kojin, Ines Martin-Martin, Helena R. C. Araújo, Brian Bonilla, Alvaro Molina-Cruz, Eric Calvo, Margareth L. Capurro and Zach N. Adelman

    Citation: Malaria Journal 2021 20:11

    Content type: Research

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  34. Plasmodium falciparum causes the majority of malaria cases worldwide and children in sub-Saharan Africa are the most vulnerable group affected. Non-sterile clinical immunity that protects from symptoms develops s...

    Authors: Triniti C. Turner, Charles Arama, Aissata Ongoiba, Safiatou Doumbo, Didier Doumtabé, Kassoum Kayentao, Jeff Skinner, Shanping Li, Boubacar Traore, Peter D. Crompton and Anton Götz

    Citation: Malaria Journal 2021 20:9

    Content type: Research

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  35. It is frequently said that funding is essential to ensure optimal results from a malaria intervention control. However, in recent years, the capacity of the government of Mozambique to sustain the operational ...

    Authors: Neide Canana

    Citation: Malaria Journal 2021 20:8

    Content type: Research

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  36. Malaria is known as a disease of poverty because of its dominance in poverty-stricken areas. Madhya Pradesh state in central India is one of the most vulnerable states for malaria morbidity and mortality. Soci...

    Authors: Ravendra K. Sharma, Harsh Rajvanshi, Praveen K. Bharti, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Kalyan B. Saha, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal

    Citation: Malaria Journal 2021 20:7

    Content type: Research

    Published on:

  37. Consistent use of insecticide-treated nets (ITNs) and intermittent preventive treatment in pregnancy (IPTp) have been recommended as cost-effective interventions for malaria prevention during pregnancy in ende...

    Authors: Solomon Tsebeni Wafula, Hilbert Mendoza, Aisha Nalugya, David Musoke and Peter Waiswa

    Citation: Malaria Journal 2021 20:5

    Content type: Research

    Published on:

  38. Rapid diagnostic tests (RDTs) play a key role in malaria case management. The most widely used RDT identifies Plasmodium falciparum based on immunochromatographic recognition of P. falciparum histidine-rich prote...

    Authors: Sam L. Nsobya, Andrew Walakira, Elizabeth Namirembe, Moses Kiggundu, Joaniter I. Nankabirwa, Emmanuel Ruhamyankaka, Emmanuel Arinaitwe, Melissa D. Conrad, Moses R. Kamya, Grant Dorsey and Philip J. Rosenthal

    Citation: Malaria Journal 2021 20:4

    Content type: Research

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  39. Kniphofia foliosa is a flamboyant robust perennial herb which has dense clumps and tick upright rhizomes with leaves at the base. In Ethiopia, it has several vernacular names including Abelbila, Ashenda, Amelmela

    Authors: Yonatan Alebachew, Daniel Bisrat, Solomon Tadesse and Kaleab Asres

    Citation: Malaria Journal 2021 20:3

    Content type: Research

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  40. There is a global consensus that new intervention tools are needed for the final steps toward malaria elimination/eradication. In a recent study in Burkina Faso, the Lehmann Funnel Entry Trap (LFET) has shown ...

    Authors: Roger Sanou, Hamidou Maïga, Etienne M. Bilgo, Simon P. Sawadogo, Bazoumana B. D. Sow, Adama Ouema, Koama Bayili, Adrien Marie Gaston Belem, Léa Paré Toé, Roch K. Dabiré and Abdoulaye Diabaté

    Citation: Malaria Journal 2021 20:2

    Content type: Research

    Published on:

  41. In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strat...

    Authors: Lamine Mahaman Moustapha, Rafiou Adamou, Maman Laminou Ibrahim, Mariama Abdoulaye Louis Padounou, Abdoulaye Diallo, David Courtin, Jean Testa and Jean Louis Abdourahim Ndiaye

    Citation: Malaria Journal 2021 20:1

    Content type: Research

    Published on:

  42. While the World Health Organization (WHO) Southeast Asia region has the second highest incidence of malaria worldwide, malaria in Vietnam is focal to few provinces, where delayed parasite clearance to anti-mal...

    Authors: Bui Van Long, Genevieve Allen, Melanie Brauny, Le Thi Kieu Linh, Srinivas Reddy Pallerla, Tran Thi Thu Huyen, Hoang Van Tong, Nguyen Linh Toan, Do Quyet, Ho Anh Son and Thirumalaisamy P. Velavan

    Citation: Malaria Journal 2020 19:458

    Content type: Research

    Published on:

  43. The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African cou...

    Authors: Mogahed Ismail Hassan Hussein, Ahmed Abdalazim Dafallah Albashir, Omer Ali Mohamed Ahmed Elawad and Anmar Homeida

    Citation: Malaria Journal 2020 19:457

    Content type: Review

    Published on:

  44. Understanding the molecular basis of insecticide resistance in mosquito, such as Anopheles funestus, is an important step in developing strategies to mitigate the resistance problem. This study aims to assess the...

    Authors: Genevieve M. Tchigossou, Seun M. Atoyebi, Romaric Akoton, Eric Tossou, Djegbe Innocent, Jacob Riveron, Helen Irving, Akadiri Yessoufou, Charles Wondji and Rousseau Djouaka

    Citation: Malaria Journal 2020 19:456

    Content type: Research

    Published on:

  45. Malaria in pregnancy remains a major contributor to maternal and infant morbidity and mortality despite scale up in interventions. Its prevention is one of the major interventions in reducing maternal and infa...

    Authors: Maria Imaobong Ibegu, Khadeejah Liman Hamza, Chukwuma David Umeokonkwo, Tamuno-Wari Numbere, Adolphe Ndoreraho and Tukur Dahiru

    Citation: Malaria Journal 2020 19:455

    Content type: Research

    Published on:

  46. Pyrethroid-treated mosquito nets are currently the mainstay of vector control in Côte d’Ivoire. However, resistance to pyrethroids has been reported across the country, limiting options for insecticide resista...

    Authors: Bernard L. Kouassi, Constant Edi, Emmanuel Tia, Lucien Y. Konan, Maurice A. Akré, Alphonsine A. Koffi, Allassane F. Ouattara, Antoine Mea Tanoh, Pascal Zinzindohoue, Blaise Kouadio, McKenzie Andre, Seth R. Irish, Jennifer Armistead, Dereje Dengela, Ndombour G. Cissé, Cecilia Flatley…

    Citation: Malaria Journal 2020 19:454

    Content type: Research

    Published on:

  47. In clinical trials of therapy for uncomplicated Plasmodium falciparum, there are usually some patients who fail treatment even in the absence of drug resistance. Treatment failures, which can be due to recrudesce...

    Authors: Rida Mumtaz, Lucy C. Okell and Joseph D. Challenger

    Citation: Malaria Journal 2020 19:453

    Content type: Research

    Published on:

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