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  1. Content type: Research

    Long-lasting insecticidal nets (LLINs) were first introduced in 2010 as a vector control intervention, to complement indoor residual spraying, to reduce malaria transmission in Zimbabwe. The objective of this ...

    Authors: Oscar Tapera

    Citation: Malaria Journal 2019 18:278

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  2. Content type: Research

    HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Dihydroartemisinin–piperaquine (DPQ) is recommended for t...

    Authors: Esperança Sevene, Clifford G. Banda, Mavuto Mukaka, Sonia Maculuve, Salésio Macuacua, Anifa Vala, Mireia Piqueras, Linda Kalilani-Phiri, Jane Mallewa, Dianne J. Terlouw, Saye H. Khoo, David G. Lalloo and Victor Mwapasa

    Citation: Malaria Journal 2019 18:277

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  3. Content type: Research

    Parasites from the genus Plasmodium, the aetiological agent of malaria in humans, can also infect non-human primates (NHP), increasing the potential risk of zoonotic transmission with its associated global public...

    Authors: Silvia Rondón, Cielo León, Andrés Link and Camila González

    Citation: Malaria Journal 2019 18:276

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  4. Content type: Research

    Drug resistance within the major malaria parasites Plasmodium vivax and Plasmodium falciparum threatens malaria control and elimination in Southeast Asia. Plasmodium vivax first-line treatment drug is chloroquine...

    Authors: Chaturong Noisang, Christiane Prosser, Wieland Meyer, Waenurama Chemoh, John Ellis, Nongyao Sawangjaroen and Rogan Lee

    Citation: Malaria Journal 2019 18:275

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  5. Content type: Research

    Insecticide-treated nets (ITNs) and long-lasting insecticidal nets (LLINs) are effective for malaria prevention and are designed to provide nearly 5 years of mosquito protection. However, many ITNs and LLINs b...

    Authors: Ellen M. Santos, Jenna E. Coalson, Elizabeth T. Jacobs, Yann C. Klimentidis, Stephen Munga, Maurice Agawo, Elizabeth Anderson, Nancy Stroupe and Kacey C. Ernst

    Citation: Malaria Journal 2019 18:274

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  6. Content type: Research

    Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria...

    Authors: Emily M. Stucke, Amadou Niangaly, Andrea A. Berry, Jason A. Bailey, Drissa Coulibaly, Amed Ouattara, Kirsten E. Lyke, Matthew B. Laurens, Antoine Dara, Matthew Adams, Jozelyn Pablo, Algis Jasinskas, Rie Nakajima, Albert E. Zhou, Sonia Agrawal, DeAnna J. Friedman-Klabanoff…

    Citation: Malaria Journal 2019 18:273

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  7. Content type: Research

    To assess the occurrence of Plasmodium ovale wallikeri and Plasmodium ovale curtisi species in travellers returning to Germany, two real-time PCR protocols for the detection and differentiation of the two P. oval...

    Authors: Hagen Frickmann, Christine Wegner, Stefanie Ruben, Ulrike Loderstädt and Egbert Tannich

    Citation: Malaria Journal 2019 18:272

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  8. Content type: Methodology

    Mass drug administration (MDA) is a suggested mean to accelerate efforts towards elimination and attainment of malaria-free status. There is limited evidence of suitable methods of implementing MDA programme t...

    Authors: Ronald Mulebeke, Humphrey Wanzira, Fred Bukenya, Thomas Eganyu, Kathryn Collborn, Richard Elliot, Jean-Pierre Van Geertruyden, Dorothy Echodu and Adoke Yeka

    Citation: Malaria Journal 2019 18:271

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  9. Content type: Research

    Malaria preventive measures, including long-lasting insecticide-treated bet nets (LLINs), indoor residual spraying (IRS), and controlling mosquito breeding sites, are key measures to achieve malaria eliminatio...

    Authors: Domina Asingizwe, P. Marijn Poortvliet, Constantianus J. M. Koenraadt, Arnold J. H. van Vliet, Chantal Marie Ingabire, Leon Mutesa and Cees Leeuwis

    Citation: Malaria Journal 2019 18:270

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  10. Content type: Research

    Community-delivered models have been widely used to reduce the burden of malaria. This review aimed to explore different community-delivered models and their relative effectiveness in terms of coverage and mal...

    Authors: Win Han Oo, Lisa Gold, Kerryn Moore, Paul A. Agius and Freya J. I. Fowkes

    Citation: Malaria Journal 2019 18:269

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  11. Content type: Research

    Reactive case detection (RCD) is an integral part of many malaria control and elimination programmes and can be conceived of as a way of gradually decreasing transmission. However, it is unclear under what cir...

    Authors: Nakul Chitnis, Peter Pemberton-Ross, Josh Yukich, Busiku Hamainza, John Miller, Theresa Reiker, Thomas P. Eisele and Thomas A. Smith

    Citation: Malaria Journal 2019 18:266

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  12. Content type: Research

    Natural exposure to gametocytes can result in the development of immunity against the gametocyte by the host as well as genetic diversity in the gametocyte. This study evaluated the quantity and quality of nat...

    Authors: Linda E. Amoah, Hamza B. Abagna, Ruth Ayanful-Torgby, Samuel O. Blankson and Nii A. Aryee

    Citation: Malaria Journal 2019 18:265

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  13. Content type: Research

    In 2017, more than 5 million house structures were sprayed through the U.S. President’s Malaria Initiative, protecting more than 21 million people in sub-Saharan Africa. New IRS formulations, SumiShield™ 50WG ...

    Authors: Richard M. Oxborough, Aklilu Seyoum, Yemane Yihdego, Roch Dabire, Virgile Gnanguenon, Francis Wat’senga, Fiacre R. Agossa, Gedeon Yohannes, Sylvester Coleman, Lazarus Musa Samdi, Abdoulaye Diop, Ousmane Faye, Stephen Magesa, Alphaxard Manjurano, Michael Okia, Evelyne Alyko…

    Citation: Malaria Journal 2019 18:264

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  14. Content type: Research

    Most impact prediction of malaria vector control interventions has been based on African vectors. Anopheles albimanus, the main vector in Central America and the Caribbean, has higher intrinsic mortality, is more...

    Authors: Olivier J. T. Briët, Daniel E. Impoinvil, Nakul Chitnis, Emilie Pothin, Jean Frantz Lemoine, Joseph Frederic and Thomas A. Smith

    Citation: Malaria Journal 2019 18:263

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  15. Content type: Methodology

    The Mindray BC-6800 haematology analyzer (BC-6800) provides a dedicated flag ‘Infected RBC’ (InR) and the number of InR (InR#)/the permillage of InR (InR‰) in routine blood testing as a screening tool for mala...

    Authors: Yi Sun, Daijun Xiang, Chen Chen, Shang He, Huan Qi and Chengbin Wang

    Citation: Malaria Journal 2019 18:262

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  16. Content type: Research

    More than 200 medicinal plants including Euphorbia abyssinica are utilized for treatment of malaria in Ethiopian traditional medical practices. However, the safety, efficacy and quality of these medicinal plants ...

    Authors: Abrham Belachew Muluye, Ashenafi Genanew Desta, Selamu Kebamo Abate and Gemechu Tiruneh Dano

    Citation: Malaria Journal 2019 18:261

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  17. Content type: Research

    Despite recent strides made towards reducing the emergence of artemisinin resistance, inappropriate dispensing practices for anti-malarials in both private and public sectors affect treatment outcomes negative...

    Authors: Charles Enyaah Amankwa, Harriet Affran Bonful, Kofi Agyabeng and Priscillia A. Nortey

    Citation: Malaria Journal 2019 18:260

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  18. Content type: Research

    Ensuring universal access to malaria diagnosis and treatment is a key component of Pillar 1 of the World Health Organization Global Technical Strategy for Malaria 2016–2030. To achieve this goal it is essentia...

    Authors: Cameron Taylor, Annē Linn, Wenjuan Wang, Lia Florey and Hamdy Moussa

    Citation: Malaria Journal 2019 18:258

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  19. Content type: Research

    Understanding the contribution of outdoor-resting Anopheles mosquitoes to residual malaria transmission is important in terms of scaling up vector control towards malaria elimination in South Africa. The aim of t...

    Authors: Ashley Burke, Yael Dahan-Moss, Frances Duncan, Bheki Qwabe, Maureen Coetzee, Lizette Koekemoer and Basil Brooke

    Citation: Malaria Journal 2019 18:257

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  20. Content type: Review

    Malaria was eliminated from Sri Lanka in 2012, and the country received WHO-certification in 2016. The objective of this paper is to describe the epidemiology of malaria elimination in Sri Lanka, and the key t...

    Authors: Risintha Premaratne, Rajitha Wickremasinghe, Dewanee Ranaweera, W. M. Kumudu T. de A. W. Gunasekera, Mihirini Hevawitharana, Lalanthika Pieris, Deepika Fernando and Kamini Mendis

    Citation: Malaria Journal 2019 18:256

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  21. Content type: Research

    Malaria transmission is high in western Kenya and the asymptomatic infected population plays a significant role in driving the transmission. Mathematical modelling and simulation programs suggest that interven...

    Authors: Norbert Awino Odero, Aaron M. Samuels, Wycliffe Odongo, Bernard Abong’o, John Gimnig, Kephas Otieno, Christopher Odero, David Obor, Maurice Ombok, Vincent Were, Tony Sang, Mary J. Hamel, S. Patrick Kachur, Laurence Slutsker, Kim A. Lindblade, Simon Kariuki…

    Citation: Malaria Journal 2019 18:255

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  22. Content type: Research

    Modelling risk of malaria in longitudinal studies is common, because individuals are at risk for repeated infections over time. Malaria infections result in acquired immunity to clinical malaria disease. Prosp...

    Authors: Christopher C. Stanley, Lawrence N. Kazembe, Mavuto Mukaka, Kennedy N. Otwombe, Andrea G. Buchwald, Michael G. Hudgens, Don P. Mathanga, Miriam K. Laufer and Tobias F. Chirwa

    Citation: Malaria Journal 2019 18:254

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  23. Content type: Research

    New national malaria strategic plans (NMSPs) should build upon the achievements and challenges identified during the implementation of previous plans, but there is limited research on the transition process be...

    Authors: Andrew Andrada, Samantha Herrera and Yazoumé Yé

    Citation: Malaria Journal 2019 18:253

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  24. Content type: Research

    Large-scale surveillance of molecular markers of anti-malarial drug resistance is an attractive method of resistance monitoring, to complement therapeutic efficacy studies in settings where the latter are logi...

    Authors: Sidsel Nag, Johan Ursing, Amabelia Rodrigues, Marina Crespo, Camilla Krogsgaard, Ole Lund, Frank M. Aarestrup, Michael Alifrangis and PouL-Erik Kofoed

    Citation: Malaria Journal 2019 18:252

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  25. Content type: Research

    Ecuador plans to eliminate malaria by 2020, and the country has already seen a decrease in the number of cases from more than 100,000 in 2000 to only 618 in 2015. Around 30% of malaria infections in Ecuador ar...

    Authors: Claudia A. Vera-Arias, L. Enrique Castro, Javier Gómez-Obando and Fabián E. Sáenz

    Citation: Malaria Journal 2019 18:251

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  26. Content type: Research

    The Uganda National Malaria Control Programme recognizes the importance of minimizing the effect of malaria among pregnant women. Accordingly, strategies including intermittent preventive treatment of malaria ...

    Authors: Denis Okethwangu, Jimmy Opigo, Stella Atugonza, Catherine T. Kizza, Monica Nabatanzi, Claire Biribawa, Daniel Kyabayinze and Alex R. Ario

    Citation: Malaria Journal 2019 18:250

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  27. Content type: Research

    Insecticide resistance of Anopheles stephensi, the main malaria vector in eastern Afghanistan, has been reported previously. This study describes the biochemical and molecular mechanisms of resistance to facilita...

    Authors: Noor Halim Zahid Safi, Abdul Ali Ahmadi, Sami Nahzat, Supriya Warusavithana, Naimullah Safi, Reza Valadan, Atie Shemshadian, Marzieh Sharifi, Ahmadali Enayati and Janet Hemingway

    Citation: Malaria Journal 2019 18:249

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  28. Content type: Correction

    Following publication of the original article [1], the authors advised of two errors present in the article: one concerning two author names and the other missing funding details.

    Authors: Hannah M. Edwards, Patchara Sriwichai, Kirakorn Kirabittir, Jetsumon Sattabongkot, Irwin F. Chavez and Jeffrey Hii

    Citation: Malaria Journal 2019 18:248

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    The original article was published in Malaria Journal 2019 18:221

  29. Content type: Research

    Parasite prevalence has been used widely as a measure of malaria transmission, especially in malaria endemic areas. However, its contribution and relationship to malaria mortality across different age groups h...

    Authors: Sammy Khagayi, Meghna Desai, Nyaguara Amek, Vincent Were, Eric Donald Onyango, Christopher Odero, Kephas Otieno, Godfrey Bigogo, Stephen Munga, Frank Odhiambo, Mary J. Hamel, Simon Kariuki, Aaron M. Samuels, Laurence Slutsker, John Gimnig and Penelope Vounatsou

    Citation: Malaria Journal 2019 18:247

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  30. Content type: Research

    Measures of malaria burden using microscopy and rapid diagnostic tests (RDTs) in cross-sectional household surveys may incompletely describe the burden of malaria in low-transmission settings. This study descr...

    Authors: Ashenafi Assefa, Ahmed Ali Ahmed, Wakgari Deressa, Heven Sime, Hussein Mohammed, Amha Kebede, Hiwot Solomon, Hiwot Teka, Kevin Gurrala, Brian Matei, Brian Wakeman, G. Glenn Wilson, Ipsita Sinha, Richard J. Maude, Ruth Ashton, Jackie Cook…

    Citation: Malaria Journal 2019 18:246

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  31. Content type: Research

    In light of increasing complexity of identifying and treating malaria cases in low transmission settings, operational solutions are needed to increase effective delivery of interventions. Community engagement ...

    Authors: Kimberly Baltzell, Kelly Harvard, Marguerite Hanley, Roly Gosling and Ingrid Chen

    Citation: Malaria Journal 2019 18:245

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  32. Content type: Research

    In recent years, the scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has greatly reduced malaria transmission. However, malaria remains a global public health concern with...

    Authors: Caleb Stica, Claire L. Jeffries, Seth R. Irish, Yaya Barry, Denka Camara, Ismael Yansane, Mojca Kristan, Thomas Walker and Louisa A. Messenger

    Citation: Malaria Journal 2019 18:244

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  33. Content type: Research

    Malaria vector control is dependent on chemical insecticides applied to walls by indoor residual spraying or on long-lasting insecticidal nets. The emergence and spread of insecticide resistance in major malar...

    Authors: Silas Agumba, John E. Gimnig, Lilian Ogonda, Maurice Ombok, Jackline Kosgei, Stephen Munga, Benard Guyah, Seline Omondi and Eric Ochomo

    Citation: Malaria Journal 2019 18:243

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  34. Content type: Research

    The importance of submicroscopic malaria infections in high-transmission areas could contribute to maintain the parasite cycle. Regarding non-endemic areas, its importance remains barely understood because par...

    Authors: Isabel Fradejas, José Miguel Rubio, Ariadna Martín-Díaz, Juan María Herrero-Martínez, José Manuel Ruiz-Giardin, Gerardo Rojo-Marcos, María Velasco, María Calderón-Moreno, José Manuel Azcona-Gutierrez, Francisco Jesús Merino, Belén Andrés Olmo, María Espinosa, María Cuadrado, Esther González-Monte, Jerónimo Jaqueti, Juan Cuadros…

    Citation: Malaria Journal 2019 18:242

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  35. Content type: Research

    Plasmodium falciparum merozoite surface protein-1 (PfMSP-1) and -2 (PfMSP-2) are major blood-stage vaccine candidate antigens. Understanding the genetic diversity of the genes, pfmsp-1 and pfmsp-2, is important f...

    Authors: Hương Giang Lê, Jung-Mi Kang, Hojong Jun, Jinyoung Lee, Thị Lam Thái, Moe Kyaw Myint, Khin Saw Aye, Woon-Mok Sohn, Ho-Joon Shin, Tong-Soo Kim and Byoung-Kuk Na

    Citation: Malaria Journal 2019 18:241

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  36. Content type: Research

    Tak Province, at the Thai–Myanmar border, is one of three high malaria incidence areas in Thailand. This study aimed to describe and identify possible factors driving the spatiotemporal trends of disease incid...

    Authors: Chris Erwin G. Mercado, Saranath Lawpoolsri, Prayuth Sudathip, Jaranit Kaewkungwal, Amnat Khamsiriwatchara, Wirichada Pan-ngum, Surapon Yimsamran, Siam Lawawirojwong, Kevin Ho, Nattwut Ekapirat, Rapeephan R. Maude, Jacher Wiladphaingern, Verena I. Carrara, Nicholas P. J. Day, Arjen M. Dondorp and Richard J. Maude

    Citation: Malaria Journal 2019 18:240

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  37. Content type: Research

    The Plasmodium falciparum reticulocyte binding protein homolog 2b (PfRh2b) is an important P. falciparum merozoite ligand that mediates invasion of erythrocytes by interacting with a chymotrypsin-sensitive “recep...

    Authors: Cyrille K. Diédhiou, Rahama A. Moussa, Amy K. Bei, Rachel Daniels, Nasserdine Papa Mze, Daouda Ndiaye, Ngor Faye, Dyann Wirth, Alfred Amambua-Ngwa, Souleymane Mboup and Ambroise D. Ahouidi

    Citation: Malaria Journal 2019 18:239

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  38. Content type: Research

    Reactive focal mass drug administration (rfMDA), or presumptive treatment without malaria testing of household members and neighbours of a passively identified malaria case, is currently being explored as a po...

    Authors: Kimberly A. Baltzell, Alysse Maglior, Khaya Bangu, Nontokozo Mngadi, Lisa M. Prach, Brooke Whittemore, Nyasatu Ntshalintshali, Manik Saini, Nomcebo Dlamini, Simon Kunene and Michelle S. Hsiang

    Citation: Malaria Journal 2019 18:238

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  39. Content type: Research

    Basic blue 3 is a promising anti-malarial lead compound based on the π-delocalized lipophilic cation hypothesis. Its derivatives with nitrogen atoms bonded to carbon atoms at the 3- and 7-positions on the phen...

    Authors: Takahiro Tougan, Kazunori Takahashi, Mayumi Ikegami-Kawai, Masako Horiuchi, Shiho Mori, Maiko Hosoi, Toshihiro Horii, Masataka Ihara and Masayoshi Tsubuki

    Citation: Malaria Journal 2019 18:237

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  40. Content type: Research

    Malaria caused by Plasmodium vivax and Plasmodium falciparum is among the major public health problems in most endemic areas of the world. Artemisinin-based combination therapy (ACT) has been recommended as a fir...

    Authors: Sileshi Belew, Sultan Suleman, Tesfaye Mohammed, Yimer Mekonnen, Markos Duguma, Henok Teshome, Bikila Bayisa, Evelien Wynendaele, Matthias D’Hondt, Luc Duchateau and Bart De Spiegeleer

    Citation: Malaria Journal 2019 18:236

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  41. Content type: Research

    China’s 1-3-7 approach was extensively implemented to monitor the timeframe of case reporting, case investigation and foci response in the malaria elimination. However, activities before diagnosis and reportin...

    Authors: Ting Wang, Shui-Sen Zhou, Jun Feng, Myo Minn Oo, Jing Chen, Chang-Fu Yan, Yi Zhang and Ping Tie

    Citation: Malaria Journal 2019 18:235

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  42. Content type: Research

    Given the central importance of anti-malarial drugs in the treatment of malaria, there is a need to understand the effect of Plasmodium infection on the broad spectrum of drug metabolizing enzymes. Previous studi...

    Authors: Sylvie M. Mimche, Choon-myung Lee, Ken H. Liu, Patrice N. Mimche, R. Donald Harvey, Thomas J. Murphy, Beatrice A. Nyagode, Dean P. Jones, Tracey J. Lamb and Edward T. Morgan

    Citation: Malaria Journal 2019 18:234

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  43. Content type: Research

    With an overall decline of malaria incidence, elimination of malaria is gradually becoming the next target for many of countries affected by the disease. In Kenya the national malaria control strategy is aimin...

    Authors: Ismail Mahat Bashir, Nancy Nyakoe and Marianne van der Sande

    Citation: Malaria Journal 2019 18:233

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  44. Content type: Research

    In a background of renewed calls for malaria eradication, several endemic countries in sub-Saharan Africa are contemplating malaria elimination nationally or sub-nationally. In Mozambique, a strategy to elimin...

    Authors: Harvie P. Portugaliza, Beatriz Galatas, Hoticha Nhantumbo, Helder Djive, Ilda Murato, Francisco Saúte, Pedro Aide, Christopher Pell and Khátia Munguambe

    Citation: Malaria Journal 2019 18:232

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  45. Content type: Research

    Artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DHA/PPQ) are the recommended first- and second-line treatments, respectively, for uncomplicated falciparum malaria in Somalia. The studies repor...

    Authors: Marian Warsame, Abdillahi Mohamed Hassan, Abdikarim Hussein Hassan, Ali Mohamed Jibril, Nimol Khim, Abdulkadir Mohamed Arale, Ahamed Hassan Gomey, Zainab Said Nur, Said Mohamed Osman, Marian Said Mohamed, Ali Abdulrahman, Fahmi Essa Yusuf, Jamal Ghilan Hefzullah Amran, Benoit Witkowski and Pascal Ringwald

    Citation: Malaria Journal 2019 18:231

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  46. Content type: Research

    Malaria was eliminated in Spain in 1964. Since then, more than 10,000 cases of malaria have been reported, mostly in travellers and migrants, making it the most frequently imported disease into this country. I...

    Authors: Zaida Herrador, Beatriz Fernández-Martinez, Víctor Quesada-Cubo, Oliva Diaz-Garcia, Rosa Cano, Agustín Benito and Diana Gómez-Barroso

    Citation: Malaria Journal 2019 18:230

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  47. Content type: Research

    Intermittent preventive treatment during pregnancy (IPTp) is a highly-recommended intervention to prevent maternal and neonatal complications associated with malaria infection. Despite fairly high antenatal ca...

    Authors: Shraddha Bajaria, Charles Festo, Sigilbert Mrema, Josephine Shabani, Ellen Hertzmark and Ramadhani Abdul

    Citation: Malaria Journal 2019 18:229

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  48. Content type: Research

    Agro-ecological systems have been associated with increased malaria intensity. This study determined association between different agro-ecological systems, prevalence of malaria parasitaemia and anaemia in Mvo...

    Authors: Susan F. Rumisha, Elizabeth H. Shayo and Leonard E. G. Mboera

    Citation: Malaria Journal 2019 18:228

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  49. Content type: Research

    The wide distribution of malaria mosquito breeding sites within tropical environments limits the mosquito larval source management efforts to control malaria. Rice farming contributes substantially in supporti...

    Authors: Humphrey D. Mazigo, Leonard E. G. Mboera, Susan F. Rumisha and Eliningaya J. Kweka

    Citation: Malaria Journal 2019 18:226

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