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  1. Recent malaria control efforts in mainland Tanzania have led to progressive changes in the prevalence of malaria infection in children, from 18.1% (2008) to 7.3% (2017). As the landscape of malaria transmissio...

    Authors: Sumaiyya G. Thawer, Frank Chacky, Manuela Runge, Erik Reaves, Renata Mandike, Samwel Lazaro, Sigsbert Mkude, Susan F. Rumisha, Claud Kumalija, Christian Lengeler, Ally Mohamed, Emilie Pothin, Robert W. Snow and Fabrizio Molteni

    Citation: Malaria Journal 2020 19:177

    Content type: Research

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  2. Malaria incidence has reached staggering numbers in Venezuela. Commonly, Bolívar State accounted for approximately 70% of the country cases every year. Most cases cluster in the Sifontes municipality, a region...

    Authors: M. Andreína Pacheco, David A. Forero-Peña, Kristan A. Schneider, Melynar Chavero, Angel Gamardo, Luisamy Figuera, Esha R. Kadakia, María E. Grillet, Joseli Oliveira-Ferreira and Ananias A. Escalante

    Citation: Malaria Journal 2020 19:176

    Content type: Research

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  3. Reactive case detection (RCD) seeks to enhance malaria surveillance and control by identifying and treating parasitaemic individuals residing near index cases. In Zambia, this strategy starts with passive dete...

    Authors: Fiona R. P. Bhondoekhan, Kelly M. Searle, Harry Hamapumbu, Mukuma Lubinda, Japhet Matoba, Michael Musonda, Ben Katowa, Timothy M. Shields, Tamaki Kobayashi, Douglas E. Norris, Frank C. Curriero, Jennifer C. Stevenson, Philip E. Thuma and William J. Moss

    Citation: Malaria Journal 2020 19:175

    Content type: Research

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  4. Surveillance of outdoor host-seeking malaria vectors is crucial to monitor changes in vector biting behaviour and evaluate the impact of vector control interventions. Human landing catch (HLC) has been conside...

    Authors: Teshome Degefa, Delenasaw Yewhalaw, Guofa Zhou, Harrysone Atieli, Andrew K. Githeko and Guiyun Yan

    Citation: Malaria Journal 2020 19:174

    Content type: Research

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  5. It is assumed that malaria vectors feed on locally available nectar sources to obtain energy. Sugar feeding is energetically critical for the Anopheles male swarming and mating activities. However, little is know...

    Authors: Charles Nignan, Abdoulaye Niang, Hamidou Maïga, Simon Péguédwindé Sawadogo, Bèwadéyir Serge Poda, Olivier Gnankine, Kounbobr Roch Dabiré, Frédéric Tripet and Abdoulaye Diabaté

    Citation: Malaria Journal 2020 19:173

    Content type: Research

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  6. This study evaluated the effectiveness of improved housing on indoor residual mosquito density and exposure to infected Anophelines in Minkoameyos, a rural community in southern forested Cameroon.

    Authors: Rachel L. Nguela, Jude D. Bigoga, Tedjou N. Armel, Tallah Esther, Dongmo Line, Njeambosay A. Boris, Tchouine Frederic, Riksum Kazi, Peter Williams, Wilfred F. Mbacham and Rose G. F. Leke

    Citation: Malaria Journal 2020 19:172

    Content type: Research

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  7. Antibodies (Ab) play a significant role in immunity to Plasmodium falciparum malaria. Usually, following repeated exposure to pathogens, affinity maturation and clonal selection take place, resulting in increased...

    Authors: Diane Wallace Taylor, Naveen Bobbili, Alex Kayatani, Samuel Tassi Yunga, Winifrida Kidima and Rose F. G. Leke

    Citation: Malaria Journal 2020 19:171

    Content type: Research

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  8. Malaria continues to be a disease of massive burden in Africa, and the public health resources targeted at surveillance, prevention, control, and intervention comprise large outlays of expense. Malaria transmi...

    Authors: Sadie J. Ryan, Catherine A. Lippi and Fernanda Zermoglio

    Citation: Malaria Journal 2020 19:170

    Content type: Research

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  9. Between 2011 and 2018, an estimated 134.8 million pyrethroid-treated long-lasting insecticidal nets (LLINs) were distributed nationwide in the Democratic Republic of Congo (DRC) for malaria control. Pyrethroid...

    Authors: Francis Wat’senga, Fiacre Agossa, Emile Z. Manzambi, Gillon Illombe, Tania Mapangulu, Tamfum Muyembe, Tiffany Clark, Mame Niang, Ferdinand Ntoya, Aboubacar Sadou, Mateusz Plucinski, Yikun Li, Louisa A. Messenger, Christen Fornadel, Richard M. Oxborough and Seth R. Irish

    Citation: Malaria Journal 2020 19:169

    Content type: Research

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  10. Naturally acquired immunity (NAI), which is characterized by protection against overt clinical disease and high parasitaemia, is acquired with age and transmission intensity. The role of NAI on the efficacy of...

    Authors: Christine N. L. Wanjala, Elke Bergmann-Leitner, Hoseah M. Akala, Geoffrey Odhiambo, Bernhards R. Ogutu, Ben Andagalu, Edwin Kamau and Daniel Ochiel

    Citation: Malaria Journal 2020 19:168

    Content type: Research

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  11. Cerebral malaria (CM), is a life-threatening childhood malaria syndrome with high mortality. CM is associated with impaired consciousness and neurological damage. It is not fully understood, as yet, why some c...

    Authors: Samuel Eneọjọ Abah, Florence Burté, Steven A. Howell, Ikeoluwa Lagunju, Wuraola A. Shokunbi, Mats Wahlgren, Olugbemiro Sodeinde, Biobele J. Brown, Anthony A. Holder and Delmiro Fernandez-Reyes

    Citation: Malaria Journal 2020 19:167

    Content type: Research

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  12. The Senegal National Malaria Control Programme (NMCP) introduced home-based malaria management for all ages, with diagnosis by rapid diagnostic test (RDT) and treatment with artemisinin-based combination thera...

    Authors: Seynabou Gaye, Janelle Kibler, Jean Louis Ndiaye, Mame Birame Diouf, Annē Linn, Alioune Badara Gueye, Fatou Ba Fall, Médoune Ndiop, Ibrahima Diallo, Moustapha Cisse, Mady Ba and Julie Thwing

    Citation: Malaria Journal 2020 19:166

    Content type: Case study

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  13. Patients with sickle cell disease (SCD), an inherited haemoglobinopathy, have increased risk of malaria, at least in part due to impaired splenic function. Infection with Plasmodium falciparum in SCD patients can...

    Authors: Richard O. Mwaiswelo, William Mawala, Per O. Iversen, Mariane de Montalembert, Lucio Luzzatto and Julie Makani

    Citation: Malaria Journal 2020 19:165

    Content type: Case report

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  14. Malaria control in Tanzania currently relies primarily on long-lasting insecticidal nets and indoor residual spraying, alongside effective case management and behaviour change communication. This study explore...

    Authors: Marceline F. Finda, Nicola Christofides, Javier Lezaun, Brian Tarimo, Prosper Chaki, Ann H. Kelly, Ntuli Kapologwe, Paul Kazyoba, Basiliana Emidi and Fredros O. Okumu

    Citation: Malaria Journal 2020 19:164

    Content type: Research

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  15. Insecticide-treated net (ITN) use is the core intervention among the strategies against malaria in sub-Saharan Africa (SSA) and the percentage of ITN ownership has increased from 47% in 2010 to 72% in 2017 acr...

    Authors: Hana Kim, F. DeWolfe Miller, Andres Hernandez, Frank Tanser, Polycarp Mogeni and Diego F. Cuadros

    Citation: Malaria Journal 2020 19:163

    Content type: Research

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  16. Plasmodium falciparum resistance against artemisinin has not emerged in Africa; however, there are reports of the presence of polymerase chain reaction-determined residual submicroscopic parasitaemia detected on ...

    Authors: Richard Mwaiswelo and Bill Ngasala

    Citation: Malaria Journal 2020 19:162

    Content type: Review

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  17. Case management is one of the principal strategies for malaria control. This study aimed to estimate the economic costs of uncomplicated malaria case management and explore the influence of health-seeking beha...

    Authors: Diamantina Moreno-Gutierrez, Angel Rosas-Aguirre, Alejandro Llanos-Cuentas, Joke Bilcke, José Luis Barboza, Marie-Pierre Hayette, Juan Contreras-Mancilla, Kristhian Aguirre, Dionicia Gamboa, Hugo Rodriguez, Niko Speybroeck and Philippe Beutels

    Citation: Malaria Journal 2020 19:161

    Content type: Research

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  18. Malaria in pregnancy increases the risk of deleterious maternal and birth outcomes. The use of ≥ 3 doses of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria (IPTp-SP) is recommen...

    Authors: Wigilya P. Mikomangwa, Omary Minzi, Ritah Mutagonda, Vito Baraka, Eulambius M. Mlugu, Eleni Aklillu and Appolinary A. R. Kamuhabwa

    Citation: Malaria Journal 2020 19:160

    Content type: Research

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  19. Profiling immune responses induced by either infection or vaccination can provide insight into identification of correlates of protection. Furthermore, profiling of serological responses can be used to identif...

    Authors: Jessica S. Bolton, Sidhartha Chaudhury, Sheetij Dutta, Scott Gregory, Emily Locke, Tony Pierson and Elke S. Bergmann-Leitner

    Citation: Malaria Journal 2020 19:159

    Content type: Methodology

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  20. Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation of...

    Authors: Joshua Yukich, Logan Stuck, Sara Scates, Janna Wisniewski, Frank Chacky, Charles Festo, George Kabulika, Kanuth Dimoso, Renata Mandike, George Greer, Naomi Serbantez, Ester Elisaria, Waziri Nyoni, David Dadi, Ikupa Akim, Christian Lengeler…

    Citation: Malaria Journal 2020 19:158

    Content type: Case study

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  21. The indigenous population is considered a highly susceptible group to malaria because individuals usually live in areas with high exposure to Anopheles and poverty, and have limited access to health services. The...

    Authors: Jehidys Montiel, Lina M. Zuluaga, Daniel C. Aguirre, Cesar Segura, Alberto Tobon-Castaño and Ana M. Vásquez

    Citation: Malaria Journal 2020 19:157

    Content type: Research

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  22. India has launched the malaria elimination initiative in February 2016. Studies suggest that estimates of malaria are useful to rationalize interventions and track their impact. Hence, a national study was lau...

    Authors: Ashwani Kumar, Himanshu K. Chaturvedi, Ajeet Kumar Mohanty, Surya Kant Sharma, Mantoshkumar S. Malhotra and Arvind Pandey

    Citation: Malaria Journal 2020 19:156

    Content type: Research

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  23. The malaria parasite Plasmodium falciparum is a protozoan that develops in red blood cells (RBCs) and requires various host factors. For its development in RBCs, nutrients not only from the RBC cytosol but also f...

    Authors: Takahiro Tougan, Jyotheeswara R. Edula, Masayuki Morita, Eizo Takashima, Hajime Honma, Takafumi Tsuboi and Toshihiro Horii

    Citation: Malaria Journal 2020 19:155

    Content type: Research

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  24. The World Health Organization recommends three or more doses of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) to mitigate the negative effects of malaria in pregnancy ...

    Authors: Ashley Malpass, Jobiba Chinkhumba, Elizabeth Davlantes, John Munthali, Katherine Wright, Kathryn Ramsey, Peter Troell, Michael Kayange, Fannie Kachale, Don P. Mathanga, Dziko Chatata and Julie R. Gutman

    Citation: Malaria Journal 2020 19:154

    Content type: Research

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  25. In 2012, the World Health Organization recommended that pregnant women in malaria-endemic countries complete at least three (optimal) doses of intermittent preventive treatment (IPTp) using sulfadoxine-pyrimet...

    Authors: Mbonye K. Martin, Kirwana B. Venantius, Ndugga Patricia, Kikaire Bernard, Baleeta Keith, Kabagenyi Allen, Asiimwe Godfrey, Twesigye Rogers, Kadengye T. Damazo and Byonanebye M. Dathan

    Citation: Malaria Journal 2020 19:153

    Content type: Research

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  26. KwaZulu-Natal, one of South Africa’s three malaria endemic provinces, is nearing malaria elimination, reporting fewer than 100 locally-acquired cases annually since 2010. Despite sustained implementation of es...

    Authors: Jaishree Raman, Laura Gast, Ryleen Balawanth, Sofonias Tessema, Basil Brooke, Rajendra Maharaj, Givemore Munhenga, Power Tshikae, Vishan Lakan, Tshiama Mwamba, Hazel Makowa, Lindi Sangweni, Moses Mkhabela, Nompumelelo Zondo, Ernest Mohulatsi, Zuziwe Nyawo…

    Citation: Malaria Journal 2020 19:152

    Content type: Research

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  27. Cambodia targets malaria elimination by 2025. Rapid elimination will depend on successfully identifying and clearing malaria foci linked to forests. Expanding and maintaining universal access to early diagnosi...

    Authors: Dysoley Lek, James J. Callery, Chea Nguon, Mark Debackere, Siv Sovannaroth, Rupam Tripura, Marius Wojnarski, Patrice Piola, Soy Ty Khean, Kylie Manion, Sokomar Nguon, Amber Kunkel, Lieven Vernaeve, Thomas J. Peto, Emily Dantzer, Chan Davoeung…

    Citation: Malaria Journal 2020 19:151

    Content type: Meeting report

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  28. Indoor residual spraying (IRS) is a key tool for controlling and eliminating malaria by targeting vectors. To support the development of effective intervention strategies it is important to understand the impa...

    Authors: Julie-Anne A. Tangena, Chantal M. J. Hendriks, Maria Devine, Meghan Tammaro, Anna E. Trett, Ignatius Williams, Adilson José DePina, Achamylesh Sisay, Ramandimbiarijaona Herizo, Hmooda Toto Kafy, Elizabeth Chizema, Allan Were, Jennifer Rozier, Michael Coleman and Catherine L. Moyes

    Citation: Malaria Journal 2020 19:150

    Content type: Research

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  29. Malaria remains a major cause of morbidity and mortality among children in Africa. There is inadequate information regarding malaria transmission-intensity in some of the worst-affected parts of sub-Saharan Af...

    Authors: Usman Nasir Nakakana, Ismaila Ahmed Mohammed, B. O. Onankpa, Ridwan M. Jega and Nma Muhammad Jiya

    Citation: Malaria Journal 2020 19:149

    Content type: Research

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  30. Outdoor and early evening mosquito biting needs to be addressed if malaria elimination is to be achieved. While indoor-targeted interventions, such as insecticide-treated nets and indoor residual spraying, rem...

    Authors: Onyango P. Sangoro, Tegemeo Gavana, Marceline Finda, Winfrida Mponzi, Emmanuel Hape, Alex Limwagu, Nicodem J. Govella, Prosper Chaki and Fredros O. Okumu

    Citation: Malaria Journal 2020 19:148

    Content type: Research

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  31. A previous study reported that the malaria parasite Plasmodium falciparum enters an altered growth state upon extracellular withdrawal of the essential amino acid isoleucine. Parasites slowed transit through the ...

    Authors: Kyle Jarrod McLean and Marcelo Jacobs-Lorena

    Citation: Malaria Journal 2020 19:147

    Content type: Research

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  32. Countries within the Greater Mekong Sub-region (GMS) of Southeast Asia have committed to eliminating malaria by 2030. Although the malaria situation has greatly improved, malaria transmission remains at intern...

    Authors: Yuling Li, Yubing Hu, Yan Zhao, Qinghui Wang, Huguette Gaelle Ngassa Mbenda, Veerayuth Kittichai, Saranath Lawpoolsri, Jetsumon Sattabongkot, Lynette Menezes, Xiaoming Liu, Liwang Cui and Yaming Cao

    Citation: Malaria Journal 2020 19:145

    Content type: Research

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  33. While there is increasing evidence on the safety of artemisinin-based combination therapy (ACT) for the case management of malaria in early pregnancy, little is known about the association between exposure to ...

    Authors: Orvalho Augusto, Andy Stergachis, Stephanie Dellicour, Halidou Tinto, Anifa Valá, Maria Ruperez, Eusébio Macete, Seydou Nakanabo-Diallo, Adama Kazienga, Innocent Valéa, Umberto d’Alessandro, Feiko O. ter Kuile, Gregory S. Calip, Peter Ouma, Meghna Desai and Esperança Sevene

    Citation: Malaria Journal 2020 19:144

    Content type: Research

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  34. Plasmodium falciparum malaria remains one of the world’s major infectious diseases that cause most morbidity and mortality, particularly in children. In Ghana, most children below the ages of 5 years depending on...

    Authors: Renate Asare, Clement Opoku-Okrah, Kwabena Owusu Danquah, Ohene Opare-Sem, Otchere Addai-Mensah, Daniel Gyamfi, Francis Agyei Amponsah, Edward Y. Afriyie, Richard Vikpebah Duneeh, David Ntiamoah Ofosu and Michael Frimpong

    Citation: Malaria Journal 2020 19:143

    Content type: Research

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  35. Bed net utilization is one of the important methods of malaria prevention. Malaria during pregnancy is one of the fatal diseases which mostly leads to the death of the mother and the fetus. Some of the complic...

    Authors: Teklemariam Gultie, Gistane Ayele, Befikadu Tariku, Mekdes Kondale, Zerihun Zerdo, Behailu Merdekiyos, Tsegaye Tsalla, Mesfin Kote, Alemayehu Bekele, Mulugeta Shigaz, Gebrekiros Gebremichael, Feleke Gebremeskel and Alazar Baharu

    Citation: Malaria Journal 2020 19:142

    Content type: Research

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  36. Insecticide-treated nets (ITNs) are losing efficacy against pyrethroid-resistant malaria vector populations throughout Africa. Safeguarding bed net efficacy, vital for effective malaria control, requires great...

    Authors: Angela Hughes, Geraldine M. Foster, Amy Guy, Agnes Matope, Mayumi Abe, David Towers and Philip J. McCall

    Citation: Malaria Journal 2020 19:140

    Content type: Research

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  37. Dissolution of artemether (ART) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets is one of the critical quality attributes. Thus, the verification...

    Authors: Sileshi Belew, Sultan Suleman, Markos Duguma, Henok Teshome, Evelien Wynendaele, Luc Duchateau and Bart De Spiegeleer

    Citation: Malaria Journal 2020 19:139

    Content type: Research

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  38. Seasonal malaria chemoprevention (SMC) is a new strategy to prevent malaria in children under 5 years old. It has been recommended by the World Health Organization since 2012 in malaria-endemic areas with seas...

    Authors: Drissa Konaté, Sory I. Diawara, Mahamoudou Touré, Seidina A. S. Diakité, Agnès Guindo, Karim Traoré, Ayouba Diarra, Bourama Keita, Sibe Thiam, Moussa Keita, Ibrahim Sissoko, Nafomon Sogoba, Sékou F. Traoré, Donald J. Krogtad, Seydou Doumbia and Mahamadou Diakité

    Citation: Malaria Journal 2020 19:137

    Content type: Research

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  39. Since the National Malaria Elimination Action Plan was launched in China in 2010, local malaria transmission has decreased rapidly. Zero indigenous cases were reported since 2017. However, after 2010, the prop...

    Authors: Mei-hua Zhang, Sui Xu, Ya-ping Gu, Yao-bao Liu, Hong Lin, Chao-yong Xie, Yue-e Chen, Jian-feng Chen, Hua-yun Zhou, Leonard Ortega, Guo-ding Zhu and Jun Cao

    Citation: Malaria Journal 2020 19:136

    Content type: Case study

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  40. In 2006, the Senegalese National Malaria Control Programme recommended artemisinin-based combination therapy (ACT) with artemether–lumefantrine as the first-line treatment for uncomplicated Plasmodium falciparum ...

    Authors: Amy Gaye, Mouhamad Sy, Tolla Ndiaye, Katherine J. Siddle, Daniel J. Park, Awa B. Deme, Aminata Mbaye, Baba Dieye, Yaye Die Ndiaye, Daniel E. Neafsey, Angela Early, Timothy Farrell, Mamadou Samb Yade, Mamadou Alpha Diallo, Khadim Diongue, Amy Bei…

    Citation: Malaria Journal 2020 19:134

    Content type: Research

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  41. During the erythrocytic cycle, Plasmodium falciparum malaria parasites express P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) that anchor the infected erythrocytes (IE) to the vascular lining of the host. ...

    Authors: Charlotte Harmsen, Louise Turner, Susan Thrane, Adam F. Sander, Thor G. Theander and Thomas Lavstsen

    Citation: Malaria Journal 2020 19:132

    Content type: Research

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  42. China launched the National Malaria Elimination Programme (NMEP) in 2010 and set the goal that all health facilities should be able to diagnose malaria. Additionally, hospitals at all levels could treat malari...

    Authors: Gang Li, Donglan Zhang, Zhuo Chen, Da Feng, Xiaoyu Chen, Shangfeng Tang, Heejung Son, Zhenhua Wang, Yuanhang Xi and Zhanchun Feng

    Citation: Malaria Journal 2020 19:131

    Content type: Research

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  43. Several refugee settlements in Bangladesh have provided housing and medical care for the forcibly-displaced Myanmar nationals (FDMN, also known as Rohingya) population. The identification of malaria infection ...

    Authors: Austin Lu, Olivia Cote, Silvia D. Dimitrova, Gretchen Cooley, A. Alamgir, M. Salim Uzzaman, Meerjady Sabrina Flora, Yulia Widiati, Mohammad Saifuddin Akhtar, Maya Vandenent, Daniel C. Ehlman, Sarah D. Bennett, Leora R. Feldstein and Eric Rogier

    Citation: Malaria Journal 2020 19:130

    Content type: Research

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  44. Malaria control using long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) has been associated with reduced transmission throughout Africa. However, the impact of transmissi...

    Authors: Simon P. Kigozi, Ruth N. Kigozi, Adrienne Epstein, Arthur Mpimbaza, Asadu Sserwanga, Adoke Yeka, Joaniter I. Nankabirwa, Katherine Halliday, Rachel L. Pullan, Damian Rutazaana, Catherine M. Sebuguzi, Jimmy Opigo, Moses R. Kamya, Sarah G. Staedke, Grant Dorsey, Bryan Greenhouse…

    Citation: Malaria Journal 2020 19:128

    Content type: Research

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  45. Despite huge investments and implementation of effective interventions for malaria, progress has stalled, with transmission being increasingly localized among difficult-to-reach populations and outdoor-biting ...

    Authors: Roly Gosling, John Chimumbwa, Petrina Uusiku, Sara Rossi, Henry Ntuku, Kelly Harvard, Chris White, Allison Tatarsky, Daniel Chandramohan and Ingrid Chen

    Citation: Malaria Journal 2020 19:125

    Content type: Opinion

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  46. Following guidance from the US President’s Malaria Initiative, durability monitoring of DawaPlus® 2.0 brand of long-lasting insecticidal net (LLIN) distributed during the 2015/16 mass campaign was set up in three...

    Authors: Emmanuel Obi, Festus Okoh, Sean Blaufuss, Bolanle Olapeju, Joel Akilah, Okefu Oyale Okoko, Abidemi Okechukwu, Mark Maire, Kehinda Popoola, Muhammad Abdullahi Yahaya, Chigozie Jesse Uneke, Samson Awolola, Olivier Pigeon, Stella Babalola, Hannah Koenker and Albert Kilian

    Citation: Malaria Journal 2020 19:124

    Content type: Research

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  47. Malaria surveillance requires powerful tools and strategies to achieve malaria elimination. Rapid diagnostic tests for malaria (RDTs) are easily deployed on a large scale and are helpful sources of parasite DN...

    Authors: Kiswendsida Thierry Guiguemde, Yakou Dieye, Aminata Collé Lô, Magatte Ndiaye, Aminata Lam, Isaac Akhénaton Manga, Gnagna Dieng Sow, Moussa Diop, Tamba Souané, Marie Pièrre Diouf, Roger Clément Kouly Tine and Babacar Faye

    Citation: Malaria Journal 2020 19:123

    Content type: Research

    Published on:

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