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  1. Research

    Additional burden of asymptomatic and sub-patent malaria infections during low transmission season in forested tribal villages in Chhattisgarh, India

    The burden of sub-patent malaria is difficult to recognize in low endemic areas due to limitation of diagnostic tools, and techniques. Polymerase chain reaction (PCR), a molecular based technique, is one of th...

    Mehul Kumar Chourasia, Kamaraju Raghavendra, Rajendra M. Bhatt, Dipak Kumar Swain, Hemraj M. Meshram, Jayant K. Meshram, Shrity Suman, Vinita Dubey, Gyanendra Singh, Kona Madhavinadha Prasad and Immo Kleinschmidt

    Malaria Journal 2017 16:320

    Published on: 8 August 2017

  2. Research

    Estimation of malaria parasite reservoir coverage using reactive case detection and active community fever screening from census data with rapid diagnostic tests in southern Zambia: a re-sampling approach

    In areas where malaria transmission has been suppressed by vector control interventions many malaria control and elimination programmes are actively seeking new interventions to further reduce malaria prevale...

    Joshua Yukich, Adam Bennett, Rudy Yukich, Logan Stuck, Busiku Hamainza, Kafula Silumbe, Tom Smith, Nakul Chitnis, Richard W. Steketee, Timothy Finn, Thomas P. Eisele and John M. Miller

    Malaria Journal 2017 16:317

    Published on: 7 August 2017

  3. Research

    School-based diagnosis and treatment of malaria by teachers using rapid diagnostic tests and artemisinin-based combination therapy: experiences and perceptions of users and implementers of the Learner Treatment Kit, southern Malawi

    Training teachers to diagnose uncomplicated malaria using malaria rapid diagnostic tests and treat with artemisinin-based combination therapy has the potential to improve the access of primary school children ...

    Treza Mphwatiwa, Stefan Witek-McManus, Austin Mtali, George Okello, Paul Nguluwe, Hard Chatsika, Natalie Roschnik, Katherine E. Halliday, Simon J. Brooker and Don P. Mathanga

    Malaria Journal 2017 16:318

    Published on: 7 August 2017

  4. Research

    Malaria incidence among children less than 5 years during and after cessation of indoor residual spraying in Northern Uganda

    In June 2015, a malaria epidemic was confirmed in ten districts of Northern Uganda; after cessation of indoor residual spraying (IRS). Epidemic was defined as an increase in incidence per month beyond one stan...

    Allen E. Okullo, Joseph K. B. Matovu, Alex R. Ario, Jimmy Opigo, Humphrey Wanzira, David W. Oguttu and Joan N. Kalyango

    Malaria Journal 2017 16:319

    Published on: 7 August 2017

  5. Methodology

    Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays

    Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-blocking interventions. These functional bioassays measure the sporogonic development of gametocy...

    Isaie J. Reuling, Will J. R. Stone, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Rianne Siebelink-Stoter, Wouter Graumans, Kjerstin Lanke, Teun Bousema and Robert W. Sauerwein

    Malaria Journal 2017 16:315

    Published on: 5 August 2017

  6. Research

    Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study

    Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and ep...

    Angel Rosas-Aguirre, Mitchel Guzman-Guzman, Dionicia Gamboa, Raul Chuquiyauri, Roberson Ramirez, Paulo Manrique, Gabriel Carrasco-Escobar, Carmen Puemape, Alejandro Llanos-Cuentas and Joseph M. Vinetz

    Malaria Journal 2017 16:312

    Published on: 4 August 2017

  7. Research

    Host attraction and biting behaviour of Anopheles mosquitoes in South Halmahera, Indonesia

    Indonesia is home to a variety of malaria vectors whose specific bionomic traits remain largely uncharacterized. Species-specific behaviours, such as host feeding preferences, impact the dynamics of malaria tr...

    Brandyce St. Laurent, Timothy A. Burton, Siti Zubaidah, Helen C. Miller, Puji B. Asih, Amirullah Baharuddin, Sully Kosasih, Shinta, Saya Firman, William A. Hawley, Thomas R. Burkot, Din Syafruddin, Supratman Sukowati, Frank H. Collins and Neil F. Lobo

    Malaria Journal 2017 16:310

    Published on: 2 August 2017

  8. Research

    A longitudinal cohort study of malaria exposure and changing serostatus in a malaria endemic area of rural Tanzania

    Measurements of anti-malarial antibodies are increasingly used as a proxy of transmission intensity. Most serological surveys are based on the use of cross-sectional data that, when age-stratified, approximate...

    Ryan A. Simmons, Leonard Mboera, Marie Lynn Miranda, Alison Morris, Gillian Stresman, Elizabeth L. Turner, Randall Kramer, Chris Drakeley and Wendy P. O’Meara

    Malaria Journal 2017 16:309

    Published on: 2 August 2017

  9. Research

    Deployment and use of mobile phone technology for real-time reporting of fever cases and malaria treatment failure in areas of declining malaria transmission in Muheza district north-eastern Tanzania

    Early detection of febrile illnesses at community level is essential for improved malaria case management and control. Currently, mobile phone-based technology has been commonly used to collect and transfer he...

    Filbert Francis, Deus S. Ishengoma, Bruno P. Mmbando, Acleus S. M. Rutta, Mwelecele N. Malecela, Benjamin Mayala, Martha M. Lemnge and Edwin Michael

    Malaria Journal 2017 16:308

    Published on: 1 August 2017

  10. Methodology Article

    Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites

    Malaria research is greatly dependent on and has drastically advanced with the possibility of genetically modifying Plasmodium parasites. The commonly used transfection protocol by Janse and colleagues utilizes b...

    Gesine Kaiser, Mariana De Niz, Paul-Christian Burda, Livia Niklaus, Rebecca Limenitakis Stanway and Volker Heussler

    Malaria Journal 2017 16:305

    Published on: 1 August 2017

  11. Research

    Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana

    Recent advances in malaria control efforts have led to an increased number of national malaria control programmes implementing pre-elimination measures and demonstrated the need to develop new tools to track a...

    Festus K. Acquah, Evans K. Obboh, Kwame Asare, Johnson N. Boampong, Samuel Victor Nuvor, Susheel K. Singh, Michael Theisen, Kim C. Williamson and Linda Eva Amoah

    Malaria Journal 2017 16:306

    Published on: 1 August 2017

  12. Research

    Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria

    One-fourth of children with cerebral malaria (CM) retain cognitive sequelae up to 2 years after acute disease. The kynurenine pathway of the brain, forming neuroactive metabolites, e.g. the NMDA-receptor antag...

    Dag Holmberg, Elisabeth Franzén-Röhl, Richard Idro, Robert O. Opoka, Paul Bangirana, Carl M. Sellgren, Ronny Wickström, Anna Färnert, Lilly Schwieler, Göran Engberg and Chandy C. John

    Malaria Journal 2017 16:303

    Published on: 28 July 2017

  13. Research

    Tracking development assistance and government health expenditures for 35 malaria-eliminating countries: 1990–2017

    Donor financing for malaria has declined since 2010 and this trend is projected to continue for the foreseeable future. These reductions have a significant impact on lower burden countries actively pursuing el...

    Rima Shretta, Brittany Zelman, Maxwell L. Birger, Annie Haakenstad, Lavanya Singh, Yingying Liu and Joseph Dieleman

    Malaria Journal 2017 16:251

    Published on: 27 July 2017

  14. Research

    Population-level estimates of the proportion of Plasmodium vivax blood-stage infections attributable to relapses among febrile patients attending Adama Malaria Diagnostic Centre, East Shoa Zone, Oromia, Ethiopia

    Malaria is ranked as the leading communicable disease in Ethiopia, where Plasmodium falciparum and Plasmodium vivax are co-endemic. The incidence of P. vivax is usually considered to be less seasonal than P. falc...

    Lemu Golassa and Michael T. White

    Malaria Journal 2017 16:301

    Published on: 27 July 2017

  15. Research

    Malaria epidemiology in low-endemicity areas of the northern coast of Ecuador: high prevalence of asymptomatic infections

    The recent scale-up in malaria control measures in Latin America has resulted in a significant decrease in the number of reported cases in several countries including Ecuador, where it presented a low malaria ...

    Fabián E. Sáenz, Andrea Arévalo-Cortés, Gabriela Valenzuela, Andrés F. Vallejo, Angélica Castellanos, Andrea C. Poveda-Loayza, Juan B. Gutierrez, Alvaro Alvarez, Yi Heng Yan, Yoldy Benavides, Luis Enrique Castro, Myriam Arévalo-Herrera and Sócrates Herrera

    Malaria Journal 2017 16:300

    Published on: 26 July 2017

  16. Research

    Status of insecticide resistance in Anopheles mosquitoes in Ubon Ratchathani province, Northeastern Thailand

    Malaria is common in hilly, forested areas along national borders in Southeast Asia. Insecticide resistance in malaria vectors has been detected in a few countries in the Greater Mekong sub-region (GMS), repre...

    Anchana Sumarnrote, Hans J. Overgaard, Nattapol Marasri, Bénédicte Fustec, Kanutcharee Thanispong, Theeraphap Chareonviriyaphap and Vincent Corbel

    Malaria Journal 2017 16:299

    Published on: 25 July 2017

  17. Opinion

    Challenges to replace ACT as first-line drug

    The spread of artemisinin and partner drug resistance through Asia requires changes in first-line therapy. The traditional modus has been the replacement of one first-line anti-malarial regimen with another. T...

    Aung Pyae Phyo and Lorenz von Seidlein

    Malaria Journal 2017 16:296

    Published on: 24 July 2017

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