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  1. Content type: Research

    Analysis of anti-malarial antibody responses has the potential to improve characterization of the variation in exposure to infection in low transmission settings, where conventional measures, such as entomolog...

    Authors: Henry Surendra, Mahardika A. Wijayanti, Elsa H. Murhandarwati, Irnawati, Titik Yuniarti, Mardiati, Herdiana, Maria E. Sumiwi, William A. Hawley, Neil F. Lobo, Jackie Cook, Chris Drakeley and Supargiyono

    Citation: Malaria Journal 2019 18:227

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  2. Content type: Methodology

    Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potentially preclude/pre-empt the detection of s...


    Citation: Malaria Journal 2019 18:225

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  3. Content type: Research

    PermaNet® 3.0 is a deltamethrin-treated combination long-lasting insecticidal net with the addition of synergist piperonylbutoxide (PBO) on its roof section. It is designed to overcome the challenge posed by pyre...

    Authors: Abaynesh Birhanu, Abebe Asale and Delenasaw Yewhalaw

    Citation: Malaria Journal 2019 18:224

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  4. Content type: Research

    Brazil has considerably reduced the number of cases of malaria in recent years and aims to eradicate the disease completely, however, vivax malaria continues to be a major challenge for the health system. In t...

    Authors: Felipe Leão Gomes Murta, Maxwell Oliveira Mendes, Vanderson Souza Sampaio, Abrahim Sena Baze Junior, Ximena Pamela Díaz-Bermúdez, Wuelton Marcelo Monteiro and Marcus Vinícius Guimarães Lacerda

    Citation: Malaria Journal 2019 18:223

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  5. Content type: Research

    The ability of malaria (Plasmodium) parasites to adjust investment into sexual transmission stages versus asexually replicating stages is well known, but plasticity in other traits underpinning the replication ra...

    Authors: Philip L. G. Birget, Kimberley F. Prior, Nicholas J. Savill, Lewis Steer and Sarah E. Reece

    Citation: Malaria Journal 2019 18:222

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  6. Content type: Research

    A mixed methods study was conducted to look at the magnitude of residual malaria transmission (RMT) and factors contributing to low (< 1% prevalence), but sustained transmission in rural communities on the Th...

    Authors: Hannah M. Edwards, Patchara Sriwichai, Kirakorn Kirabittir, Jetsumon Prachumsri, Irwin F. Chavez and Jeffrey Hii

    Citation: Malaria Journal 2019 18:221

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    The Correction to this article has been published in Malaria Journal 2019 18:248

  7. Content type: Research

    Zanzibar has maintained malaria prevalence below 1% for the past decade, yet elimination remains elusive despite high coverage of core vector control interventions. As part of a study investigating the magnitu...

    Authors: April Monroe, Kimberly Mihayo, Fredros Okumu, Marceline Finda, Sarah Moore, Hannah Koenker, Matthew Lynch, Khamis Haji, Faiza Abbas, Abdullah Ali, George Greer and Steven Harvey

    Citation: Malaria Journal 2019 18:220

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  8. Content type: Methodology

    Deep sequencing of targeted genomic regions is becoming a common tool for understanding the dynamics and complexity of Plasmodium infections, but its lower limit of detection is currently unknown. Here, a new amp...

    Authors: Angela M. Early, Rachel F. Daniels, Timothy M. Farrell, Jonna Grimsby, Sarah K. Volkman, Dyann F. Wirth, Bronwyn L. MacInnis and Daniel E. Neafsey

    Citation: Malaria Journal 2019 18:219

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  9. Content type: Research

    Malaria eradication globally is yet to be achieved and transmission is sustained in many endemic countries. Plasmodium falciparum continues to develop resistance to currently available anti-malarial drugs, posing...

    Authors: Titilope M. Dokunmu, Cynthia U. Adjekukor, Omolara F. Yakubu, Adetutu O. Bello, Jarat O. Adekoya, Olugbenga Akinola, Emmanuel O. Amoo and Abiodun H. Adebayo

    Citation: Malaria Journal 2019 18:218

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  10. Content type: Review

    The intensification of malaria control interventions has resulted in its global decline, but it remains a significant public health burden especially in sub-Saharan Africa (sSA). Knowledge on the parasite dive...

    Authors: Tobias O. Apinjoh, Amed Ouattara, Vincent P. K. Titanji, Abdoulaye Djimde and Alfred Amambua-Ngwa

    Citation: Malaria Journal 2019 18:217

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  11. Content type: Research

    Slash and burn cultivators are a significant risk group for malaria in South-East Asia. As envisaged in the National Strategic Plan for Malaria Elimination, Bangladesh aims to achieve zero indigenous malaria t...

    Authors: Avijit Saha, Malabika Sarker, Moktadir Kabir, Guangyu Lu and Olaf Müller

    Citation: Malaria Journal 2019 18:216

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  12. Content type: Methodology

    Reverse genetics approaches have become powerful tools to dissect the biology of malaria parasites. In a previous study, development of an in vitro drug selection method for generating transgenic parasite of Plas...

    Authors: Akira Soga, Takahiro Shirozu, Mami Ko-ketsu and Shinya Fukumoto

    Citation: Malaria Journal 2019 18:215

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  13. Content type: Research

    Undesirable consequences of donor Plasmodium falciparum parasitaemia on stored donor blood have been reported. Therefore, it is imperative that all prospective blood donors are screened for P. falciparum infectio...

    Authors: Enoch Aninagyei, Stella Smith-Graham, Alex Boye, Alexander Egyir-Yawson and Desmond Omane Acheampong

    Citation: Malaria Journal 2019 18:214

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  14. Content type: Research

    Malaria represents a worldwide medical emergency affecting mainly poor areas. Plasmodium parasites during blood stages can release kinins to the extracellular space after internalization of host kininogen inside ...

    Authors: Priscilla D. S. Ventura, Carolina P. F. Carvalho, Nilana M. T. Barros, Leonardo Martins-Silva, Edilson O. Dantas, Carolina Martinez, Pollyana M. S. Melo, João B. Pesquero, Adriana K. Carmona, Marcia R. Nagaoka and Marcos L. Gazarini

    Citation: Malaria Journal 2019 18:213

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  15. Content type: Research

    In a previous study, severe and cerebral malaria have been connected with acute cochlear malfunction in children, demonstrated by a decrease of transitory evoked otoacoustic emissions (TEOAEs) reproducibility....

    Authors: Elisa Reiterer, Simon Reider, Peter Lackner, Natalie Fischer, Daniel Dejaco, Herbert Riechelmann, Patrick Zorowka, Peter G. Kremsner, Ayola Akim Adegnika, Erich Schmutzhard and Joachim Schmutzhard

    Citation: Malaria Journal 2019 18:212

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  16. Content type: Research

    Understanding the complex heterogeneity of risk factors that can contribute to an increased risk of malaria at the individual and household level will enable more effective use of control measures. The objecti...

    Authors: Walters M. Essendi, Anne M. Vardo-Zalik, Eugenia Lo, Maxwell G. Machani, Guofa Zhou, Andrew K. Githeko, Guiyun Yan and Yaw A. Afrane

    Citation: Malaria Journal 2019 18:211

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  17. Content type: Research

    There has been no local transmission of malaria in Sri Lanka for 6 years following elimination of the disease in 2012. Malaria vectors are prevalent in parts of the country, and imported malaria cases continue...

    Authors: Vissundara M. Karunasena, Manonath Marasinghe, Carmen Koo, Saliya Amarasinghe, Arundika S. Senaratne, Rasika Hasantha, Mihirini Hewavitharana, Hapuarachchige C. Hapuarachchi, Hema D. B. Herath, Rajitha Wickremasinghe, Kamini N. Mendis, Deepika Fernando and Dewanee Ranaweera

    Citation: Malaria Journal 2019 18:210

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  18. Content type: Research

    To reduce onward falciparum malaria transmission, the World Health Organization recommends adding single low-dose (SLD) primaquine to artemisinin-based combination treatment in low transmission areas. However,...

    Authors: Jaishree Raman, Elizabeth Allen, Lesley Workman, Aaron Mabuza, Hendrik Swanepoel, Gillian Malatje, John Frean, Lubbe Wiesner and Karen I. Barnes

    Citation: Malaria Journal 2019 18:209

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  19. Content type: Research

    Malaria transmission varies in intensity amongst Solomon Island villages where Anopheles farauti is the only vector. This variation in transmission intensity might be explained by density-dependent processes duri...

    Authors: Kimberley McLaughlin, Tanya L. Russell, Allan Apairamo, Hugo Bugoro, Jance Oscar, Robert D. Cooper, Nigel W. Beebe, Scott A. Ritchie and Thomas R. Burkot

    Citation: Malaria Journal 2019 18:208

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  20. Content type: Research

    Recent reductions in malaria burden have been attributed largely to long-lasting insecticidal nets (LLINs). In March–June 2017, approximately 3 years after a national LLIN distribution campaign, a cross-sectio...

    Authors: Sheila Rugnao, Samuel Gonahasa, Catherine Maiteki-Sebuguzi, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Amy Lynd, Janet Hemingway, Martin J. Donnelly, Grant Dorsey, Moses R. Kamya and Sarah G. Staedke

    Citation: Malaria Journal 2019 18:207

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  21. Content type: Research

    Routine surveillance on the therapeutic efficacy of artemisinin-based combination therapy (ACT) has been ongoing in Ghana since 2005. The sixth round of surveillance was conducted between 2015 and 2017 to dete...

    Authors: Benjamin Abuaku, Nancy O. Duah-Quashie, Lydia Quaye, Sena A. Matrevi, Neils Quashie, Akosua Gyasi, Felicia Owusu-Antwi, Keziah Malm and Kwadwo Koram

    Citation: Malaria Journal 2019 18:206

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  22. Content type: Research

    Heterogeneity in the immune response to parasite infection is mediated in part by differences in host genetics, gender, and age group. In infants and young children, ongoing immunological maturation often resu...

    Authors: Paul L. Maurizio, Hubaida Fuseini, Gerald Tegha, Mina Hosseinipour and Kristina De Paris

    Citation: Malaria Journal 2019 18:205

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  23. Content type: Correction

    Following publication of the original article [1], the authors flagged an error concerning Table 3.

    Authors: Abdou Talipouo, Carmene S. Ngadjeu, Patricia Doumbe-Belisse, Landre Djamouko-Djonkam, Nadege Sonhafouo-Chiana, Edmond Kopya, Roland Bamou, Parfait Awono-Ambene, Sylvain Woromogo, Sevilor Kekeunou, Charles S. Wondji and Christophe Antonio-Nkondjio

    Citation: Malaria Journal 2019 18:204

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    The original article was published in Malaria Journal 2019 18:167

  24. Content type: Research

    As malaria elimination becomes a goal in malaria-endemic nations, questions of feasibility become critical. This article explores the potential challenges associated with this goal and future strategies for ma...

    Authors: Nils Kaehler, Bipin Adhikari, Phaik Yeong Cheah, Lorenz von Seidlein, Nicholas P. J. Day, Daniel H. Paris, Marcel Tanner and Christopher Pell

    Citation: Malaria Journal 2019 18:203

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  25. Content type: Methodology

    Malaria remains an important public health problem in Latin America, and the development of insecticide resistance in malaria vectors poses a major threat to malaria elimination efforts. Monitoring of insectic...

    Authors: Juan C. Lol, David Castañeda, Lucy Mackenzie-Impoinvil, Carla G. Romero, Audrey Lenhart and Norma R. Padilla

    Citation: Malaria Journal 2019 18:202

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  26. Content type: Research

    The challenge in anti-malarial chemotherapy is based on the emergence of resistance to drugs and the search for medicines against all stages of the life cycle of Plasmodium spp. as a therapeutic target. Nowadays,...

    Authors: Leonardo Bonilla-Ramírez, Silvia Galiano, Miguel Quiliano, Ignacio Aldana and Adriana Pabón

    Citation: Malaria Journal 2019 18:201

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  27. Content type: Research

    Malaria is considered as a major threat to health systems. It is still considered as one of the most important infectious diseases in Iran, but with an elimination goal in 2025. This study aimed to review the ...

    Authors: Hassan Vatandoost, Ahmad Raeisi, Abedin Saghafipour, Fatemeh Nikpour and Jalil Nejati

    Citation: Malaria Journal 2019 18:200

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  28. Content type: Research

    Indoor residual spraying (IRS), the coating of interior walls of houses with insecticides, is common in malaria-endemic areas. While important in malaria control, IRS potentially exposes residents to harmful i...

    Authors: Brenda Eskenazi, David I. Levine, Stephen Rauch, Muvhulawa Obida, Madelein Crause, Riana Bornman and Jonathan Chevrier

    Citation: Malaria Journal 2019 18:199

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  29. Content type: Research

    From 2011 to 2014, an indoor residual spray (IRS) programme for malaria vectors control was implemented in six health districts in Senegal. The main objective of the present study was to evaluate the efficacy ...

    Authors: Cheikh Lo, Abdoulaye Kane Dia, Ibrahima Dia, El Hadji Amadou Niang, Lassana Konaté and Ousmane Faye

    Citation: Malaria Journal 2019 18:198

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  30. Content type: Research

    Vivax malaria is the predominant form of malaria outside Africa, affecting about 14 million people worldwide, with about 2.5 billion people exposed. Development of a Plasmodium vivax vaccine is a priority, and me...

    Authors: Chew Weng Cheng, Somchai Jongwutiwes, Chaturong Putaporntip and Andrew P. Jackson

    Citation: Malaria Journal 2019 18:197

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  31. Content type: Correction

    Following publication of the original article [1], the authors of the article flagged that their article had gone to publishing with an error in the title.

    Authors: Busisani Dube, Joseph Mberikunashe, Patience Dhliwayo, Andrew Tangwena, Gerald Shambira, Anderson Chimusoro, Munashe Madinga and Brighton Gambinga

    Citation: Malaria Journal 2019 18:196

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    The original article was published in Malaria Journal 2019 18:171

  32. Content type: Research

    The disease burden of Plasmodium falciparum malaria illness is generally estimated using one of two distinct approaches: either by transforming P. falciparum infection prevalence estimates into incidence estimate...

    Authors: Ursula Dalrymple, Ewan Cameron, Rohan Arambepola, Katherine E. Battle, Elisabeth G. Chestnutt, Suzanne H. Keddie, Katherine A. Twohig, Daniel A. Pfeffer, Harry S. Gibson, Daniel J. Weiss, Samir Bhatt and Peter W. Gething

    Citation: Malaria Journal 2019 18:195

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  33. Content type: Research

    Substantial evidence indicates that cytophilic IgG responses to Plasmodium falciparum merozoite antigens play a role in protection from malaria. The specific targets mediating immunity remain unclear. Evaluating ...

    Authors: Rafiou Adamou, Célia Dechavanne, Ibrahim Sadissou, Tania d’Almeida, Aziz Bouraima, Paulin Sonon, Roukiyath Amoussa, Gilles Cottrell, Agnès Le Port, Michael Theisen, Edmond J. Remarque, Shirley Longacre, Kabirou Moutairou, Achille Massougbodji, Adrian J. F. Luty, Gregory Nuel…

    Citation: Malaria Journal 2019 18:194

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  34. Content type: Research

    Malaria is more often considered a problem of the rural poor and the disease has been overlooked in urban settings for centuries due to the assumption that economic development in urban areas results in better...

    Authors: Temesgen File, Hunduma Dinka and Lemu Golassa

    Citation: Malaria Journal 2019 18:193

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  35. Content type: Methodology

    Mutational analysis of the Plasmodium falciparum kelch 13 (k13) gene is routinely performed to track the emergence and spread of artemisinin resistance. Surveillance of resistance markers has been impeded by the ...

    Authors: Kayvan Zainabadi, Myaing M. Nyunt and Christopher V. Plowe

    Citation: Malaria Journal 2019 18:192

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  36. Content type: Review

    Mozambique has historically been one of the countries with the highest malaria burden in the world. Starting in the 1960s, malaria control efforts were intensified in the southern region of the country, especi...

    Authors: Pedro Aide, Baltazar Candrinho, Beatriz Galatas, Khátia Munguambe, Caterina Guinovart, Fabião Luis, Alfredo Mayor, Krijn Paaijmans, Lucía Fernández-Montoya, Laia Cirera, Quique Bassat, Sonia Mocumbi, Clara Menéndez, Delino Nhalungo, Ariel Nhacolo, Regina Rabinovich…

    Citation: Malaria Journal 2019 18:190

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  37. Content type: Research

    Mosquito net use is an essential part of malaria prevention. Although previous research has shown that many people sleep under a mosquito net in endemic areas, it is unknown whether people underestimate how co...

    Authors: Jessica M. Perkins, Paul Krezanoski, Sae Takada, Bernard Kakuhikire, Vincent Batwala, Alexander C. Tsai, Nicholas A. Christakis and David R. Bangsberg

    Citation: Malaria Journal 2019 18:189

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  38. Content type: Research

    The ability of a malaria antigen to induce effective, long-lasting immune responses is important for the development of a protective malaria vaccine. Plasmodium vivax merozoite surface protein-8 (PvMSP8) has been...

    Authors: Piyawan Kochayoo, Natthapon Kittisenachai, Siriruk Changrob, Kittikorn Wangriatisak, Fauzi Muh, Patchanee Chootong and Eun-Taek Han

    Citation: Malaria Journal 2019 18:188

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  39. Content type: Research

    The propensity of different Anopheles mosquitoes to bite humans instead of other vertebrates influences their capacity to transmit pathogens to humans. Unfortunately, determining proportions of mosquitoes that ha...

    Authors: Emmanuel P. Mwanga, Salum A. Mapua, Doreen J. Siria, Halfan S. Ngowo, Francis Nangacha, Joseph Mgando, Francesco Baldini, Mario González Jiménez, Heather M. Ferguson, Klaas Wynne, Prashanth Selvaraj, Simon A. Babayan and Fredros O. Okumu

    Citation: Malaria Journal 2019 18:187

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  40. Content type: Methodology

    Whole parasite vaccination is an efficacious strategy to induce sterile immunity and to prevent malaria transmission. Understanding the mechanism and response of immune cells to vaccines plays a critical role ...

    Authors: Tanmaya Atre, Tanisha M. Robinson, Tatyana Savransky, Sheetij Dutta, Judith E. Epstein and Elke S. Bergmann-Leitner

    Citation: Malaria Journal 2019 18:186

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  41. Content type: Research

    To reduce the malaria burden in Nigeria, the country is scaling up prevention and treatment interventions, especially household ownership and use of insecticide-treated nets (ITNs). Nevertheless, large gaps re...

    Authors: Andrew Andrada, Samantha Herrera, Uwem Inyang, Audu Bala Mohammed, Perpetua Uhomoibhi and Yazoumé Yé

    Citation: Malaria Journal 2019 18:185

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  42. Content type: Correction

    Following publication of the original article [1], it came to the authors’ attention that unfortunately the last name of one of the authors is spelled incorrectly in the published article.

    Authors: Dawit Hawaria, Hallelujah Getachew, Guofa Zhou, Assalif Demissew, Kasahun Habitamu, Beka Raya, Ming-Chieh Lee, Delenasaw Yewhalaw and Guiyun Yan

    Citation: Malaria Journal 2019 18:184

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    The original article was published in Malaria Journal 2019 18:145

  43. Content type: Correction

    Please be advised that since publication of the original article [1] the authors have flagged that they omitted to provide the up-to-date version of Fig. 1 and, as such, the wrong version of Fig. 1 is present ...

    Authors: Wei-Long Tan, Chun-Xiao Li, Rui-Chen Lv, Yan-De Dong, Xiao-Xia Guo, Dan Xing, Ming-hao Zhou, Yan Xu, Hong-liang Chu, Gang Wang, Chang-qiang Zhu, Jun Sun and Tong-Yan Zhao

    Citation: Malaria Journal 2019 18:183

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    The original article was published in Malaria Journal 2019 18:164

  44. Content type: Research

    Indoor residual house spraying (IRS) and long-lasting insecticidal nets (LLINs) are the key front-line malaria vector interventions against Anopheles arabiensis, the sole primary malaria vector in Ethiopia. Unive...

    Authors: Oljira Kenea, Meshesha Balkew, Habte Tekie, Wakgari Deressa, Eskindir Loha, Bernt Lindtjørn and Hans J. Overgaard

    Citation: Malaria Journal 2019 18:182

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  45. Content type: Research

    Information on insecticide resistance and the mechanisms driving it in the major malaria vectors is grossly lacking in Niger Republic, thus hindering control efforts. To facilitate evidence-based malaria contr...

    Authors: Sulaiman S. Ibrahim, Muhammad M. Mukhtar, Helen Irving, Rabiou Labbo, Michael O. Kusimo, Izamné Mahamadou and Charles S. Wondji

    Citation: Malaria Journal 2019 18:181

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  46. Content type: Research

    HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Artemether–lumefantrine (AL) is the most commonly used AC...

    Authors: Clifford G. Banda, Mike Chaponda, Mavuto Mukaka, Modest Mulenga, Sebastian Hachizovu, Jean B. Kabuya, Joyce Mulenga, Jay Sikalima, Linda Kalilani-Phiri, Dianne J. Terlouw, Saye H. Khoo, David G. Lalloo and Victor Mwapasa

    Citation: Malaria Journal 2019 18:180

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  47. Content type: Research

    Identifying efficient and effective strategies to reach and monitor populations at greatest risk of malaria in low-transmission settings is a key challenge for malaria elimination. In Namibia’s Zambezi Region,...

    Authors: Jerry O. Jacobson, Jennifer L. Smith, Carmen Cueto, Mukosha Chisenga, Kathryn Roberts, Michelle Hsiang, Roly Gosling, Davis Mumbengegwi and Adam Bennett

    Citation: Malaria Journal 2019 18:179

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  48. Content type: Research

    Malaria, one of the world’s greatest public health challenges, is an endemic disease with stable transmission in Togo. Combating malaria requires an effective vector control. This study provides temporal data ...

    Authors: Adjovi D. Amoudji, Koffi M. Ahadji-Dabla, Aristide Sawdetuo Hien, Yawo Georges Apétogbo, Bienvenu Yaméogo, Diloma Dieudonné Soma, Rabila Bamogo, Rachid Tinah Atcha-Oubou, Roch Kounbobr Dabiré and Guillaume Koffivi Ketoh

    Citation: Malaria Journal 2019 18:177

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  49. Content type: Case report

    Plasmodium ovale curtisi and Plasmodium ovale wallikeri are regarded as less virulent forms of malaria with a geographic distribution including Southeast Asia, Central and West Africa, and is increasingly reporte...

    Authors: Rosio I. Guerra, Marianela Ore, Hugo O. Valdivia, Danett K. Bishop, Mariana Ramos, Christopher N. Mores and Wesley R. Campbell

    Citation: Malaria Journal 2019 18:176

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