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  1. Mass Drug Administration (MDA) has become a mainstay for the control of several diseases over the last two decades. Successful implementation of MDA programmes requires community participation and can be threa...

    Authors: Christian Kositz, Hristina Vasileva, Nuredin Mohammed, Jane Achan, Edgard Diniba Dabira, Umberto D’Alessandro, John Bradley and Michael Marks
    Citation: Malaria Journal 2024 23:54
  2. The infection of the liver by Plasmodium parasites is an obligatory step leading to malaria disease. Following hepatocyte invasion, parasites differentiate into replicative liver stage schizonts and, in the case ...

    Authors: Gabriel Mitchell, Laura Torres, Matthew E. Fishbaugher, Melanie Lam, Vorada Chuenchob, Reena Zalpuri, Shreya Ramasubban, Caitlin N. Baxter, Erika L. Flannery, Anke Harupa, Sebastian A. Mikolajczak and Danielle M. Jorgens
    Citation: Malaria Journal 2024 23:53
  3. Against a backdrop of stalled progress in malaria control, it is surprising that the various forms of malaria chemoprevention are not more widely used. The World Health Organization (WHO) has recommended sever...

    Authors: Jasper Littmann, Dorothy Achu, Miriam K. Laufer, Corine Karema and David Schellenberg
    Citation: Malaria Journal 2024 23:51
  4. Despite the progress made in this decade towards malaria elimination, it remains a significant public health concern in India and many other countries in South Asia and Asia Pacific region. Understanding the h...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Praveen K. Bharti, Anup R. Anvikar and Altaf A. Lal
    Citation: Malaria Journal 2024 23:50
  5. Over the last decades, the number of malaria cases has drastically reduced in Cambodia. As the overall prevalence of malaria in Cambodia declines, residual malaria transmission becomes increasingly fragmented ...

    Authors: Mathilde Grimée, Costanza Tacoli, Mirco Sandfort, Thomas Obadia, Aimee R. Taylor, Amélie Vantaux, Leanne J. Robinson, Dysoley Lek, Rhea J. Longley, Ivo Mueller, Jean Popovici, Michael T. White and Benoît Witkowski
    Citation: Malaria Journal 2024 23:49
  6. Immunogenic cell death (ICD) is a type of regulated cell death that plays a crucial role in activating the immune system in response to various stressors, including cancer cells and pathogens. However, the inv...

    Authors: Yan-hui Zhang, Li-hua Xie, Jian Li, Yan-wei Qi and Jia-jian Shi
    Citation: Malaria Journal 2024 23:48
  7. South Africa set a target to eliminate malaria by 2023, with KwaZulu-Natal (KZN) Province the malaria-endemic province closest to achieving this goal. Objective two of the National Malaria Elimination Strategi...

    Authors: Maxwell Mabona, Thembekile Zwane, Jaishree Raman, Lazarus Kuonza, Babongile Mhlongo and Poncho Phafane
    Citation: Malaria Journal 2024 23:47
  8. The aim of this study is to design ad hoc malaria learning (ML) approaches to predict clinical outcome in all patients with imported malaria and, therefore, to identify the best clinical setting.

    Authors: Alessandra D’Abramo, Francesco Rinaldi, Serena Vita, Riccardo Mazzieri, Angela Corpolongo, Claudia Palazzolo, Tommaso Ascoli Bartoli, Francesca Faraglia, Maria Letizia Giancola, Enrico Girardi and Emanuele Nicastri
    Citation: Malaria Journal 2024 23:46
  9. The male mosquito microbiome may be important for identifying ideal candidates for disease control. Among other criteria, mosquito-associated symbionts that have high localization in both male and female mosqu...

    Authors: Richardson K. Egyirifa and Jewelna Akorli
    Citation: Malaria Journal 2024 23:45
  10. Over the past thirty years, epigenetic regulation of gene expression has gained increasing interest as it was shown to be implicated in illnesses ranging from cancers to parasitic diseases. In the malaria para...

    Authors: Thibaud Reyser, Lucie Paloque, Jean-Michel Augereau, Luisa Di Stefano and Françoise Benoit-Vical
    Citation: Malaria Journal 2024 23:44
  11. Malaria remains an enduring public health concern in Indonesia, exacerbated by its equatorial climate that fosters the proliferation of Anopheles mosquitoes. This study seeks to assess the performance of the mala...

    Authors: Hamzah Hasyim, Heni Marini, Misnaniarti Misnaniarti, Rostika Flora, Iche Andriyani Liberty, Ahmed Elagali, Hartoni Hartoni and Fadhilah Eka Maharani
    Citation: Malaria Journal 2024 23:43
  12. Malaria is one of the most important vector-borne diseases of humans with an estimated 241 million cases worldwide in 2020. As an urban and periurban mosquito species, Anopheles stephensi is exposed to artificial...

    Authors: Jose Luis Llergo, Helena Garuti, Celia Lopez, Julia Sanchez and David Calvo
    Citation: Malaria Journal 2024 23:42
  13. An estimated 50% of suspected malaria cases in sub-Saharan Africa first seek care in the private sector, especially in private medicine retail outlets. Quality of care in these outlets is generally unknown but...

    Authors: Meley Woldeghebriel, Ezinne Aso, Erica Berlin, Chizoba Fashanu, Sylvia N. Kirumira, Felix Lam, Robert Mugerwa, Juliet Nakiganda, Tayo Olaleye, Jimmy Opigo, Funlola Osinupebi, Natalie Priestley, Rodger Stringham, Perpetua Uhomoibhi, Theodoor Visser, Abigail Ward…
    Citation: Malaria Journal 2024 23:41
  14. Artemisinin-based combination therapy (ACT) has been effective in the supervised treatment of uncomplicated malaria in Ghana. Since ACT usage is primarily unsupervised, this study aimed to determine the effect...

    Authors: Mawusi Adepa Mawuli, Linda Eva Amoah, Liwang Cui, Neils Ben Quashie and Yaw Asare Afrane
    Citation: Malaria Journal 2024 23:40
  15. Seasonal Malaria Chemoprevention (SMC) is a highly effective intervention for preventing malaria, particularly in areas with highly seasonal transmission. Monitoring and evaluating (M&E) SMC programmes are com...

    Authors: Monica Anna de Cola, Elisabeth G. Chestnutt, Sol Richardson, Matthieu Baudry, Chuks Nnaji, Taiwo Ibinaiye, Azoukalné Moukénet, Kunle Rotimi, Benoît Sawadogo, Joshua Okafor, Cheick Saïd Compaoré, Chibuzo Oguoma, Christian Rassi and Arantxa Roca-Feltrer
    Citation: Malaria Journal 2024 23:39
  16. It was hypothesized that glucose-6-phosphate dehydrogenase (G6PD) deficiency confers a protective effect against malaria infection, however, safety concerns have been raised regarding haemolytic toxicity cause...

    Authors: Usa Boonyuen, Beatriz Aira C. Jacob, Jutamas Wongwigkan, Kamonwan Chamchoy, Natsamon Singha-art, Natnicha Pengsuk, Duantida Songdej, Emily R. Adams, Thomas Edwards, Supat Chamnanchanunt, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis and Shamini Chandran
    Citation: Malaria Journal 2024 23:38
  17. A major challenge to malaria elimination is identifying and targeting populations that are harbouring residual infections and contributing to persistent transmission. In many near-elimination settings in South...

    Authors: Sarah Gallalee, Iska Zarlinda, Martha G. Silaen, Chris Cotter, Carmen Cueto, Iqbal R. F. Elyazar, Jerry O. Jacobson, Roly Gosling, Michelle S. Hsiang, Adam Bennett, Farah N. Coutrier and Jennifer L. Smith
    Citation: Malaria Journal 2024 23:37
  18. Timely molecular surveillance of Plasmodium falciparum kelch 13 (k13) gene mutations is essential for monitoring the emergence and stemming the spread of artemisinin resistance. Widespread artemisinin resistance,...

    Authors: Brook Jeang, Daibin Zhong, Ming-Chieh Lee, Harrysone Atieli, Delenasaw Yewhalaw and Guiyun Yan
    Citation: Malaria Journal 2024 23:36
  19. Sri Lanka after eliminating malaria in 2012, is in the prevention of re-establishment (POR) phase. Being a tropical country with high malariogenic potential, maintaining vigilance is important. All malaria cas...

    Authors: Kumudunayana T. Gunasekera, Risintha G. Premaratne, Shiroma M. Handunnetti, Jagathpriya Weerasena, Sunil Premawansa and Deepika S. Fernando
    Citation: Malaria Journal 2024 23:35
  20. The emergence and spread of artemisinin partial resistance in East and Horn of Africa is alarming. However, artemisinin-based combination therapy (ACT) generally remains efficacious for the treatment of falcip...

    Authors: Ashenafi Assefa, Abebe A. Fola and Geremew Tasew
    Citation: Malaria Journal 2024 23:34
  21. Seasonal malaria chemoprevention (SMC) is an effective intervention to prevent malaria in children in locations where the burden of malaria is high and transmission is seasonal. There is growing evidence sugge...

    Authors: Jamshed Khan, Maria Suau Sans, Francis Okot, Abubaker Rom Ayuiel, Jonathan Magoola, Christian Rassi, Sikai Huang, Denis Mubiru, Craig Bonnington, Kevin Baker, Julla Ahmed, Chuks Nnaji and Sol Richardson
    Citation: Malaria Journal 2024 23:33
  22. Despite Ethiopia’s concerted efforts to eliminate malaria by 2030, the disease continues to pose a significant public health and socioeconomic challenge in the country. The year 2021 witnessed 2.78 million mal...

    Authors: Aynalem Mandefro, Geletta Tadele, Bacha Mekonen and Lemu Golassa
    Citation: Malaria Journal 2024 23:32
  23. The emergence of insecticide resistance and outdoor transmission in malaria-endemic areas underlines the urgent need to develop innovative tools, such as spatial repellents (SR), that may circumvent this resid...

    Authors: Lepa Syahrani, Puji B. S. Asih, Anom Bowolaksono, Astari Dwiranti, Siti Zubaidah, Ismail E. Rozi, Dendi H. Permana, Claus Bøgh, Michael J. Bangs, John P. Grieco, Nicole L. Achee, Neil F. Lobo and Din Syafruddin
    Citation: Malaria Journal 2024 23:31
  24. Malaria remains a significant public health concern in Niger, with the number of cases increasing from 592,334 in 2000 to 3,138,696 in 2010. In response, a concerted campaign against the disease has been initi...

    Authors: Ali Issakou Malam Tchole, Run-Ze Ye, Qing Xu, Zhen-Wei Li, Jin-Yue Liu, Shan-Shan Wang, Jing Liu, Xiao-Yang Wang, Alassan Maman Bachir, Lin Zhao and Wu-Chun Cao
    Citation: Malaria Journal 2024 23:30
  25. In 2015, Tanzania National Malaria Control Programme (NMCP) established a longitudinal malaria vector entomological surveillance (MVES). The MVES is aimed at a periodical assessment of malaria vector compositi...

    Authors: Charles D. Mwalimu, Samson Kiware, Rosemary Nshama, Yahya Derua, Pendael Machafuko, Peter Gitanya, Winfred Mwafongo, Jubilate Bernard, Basiliana Emidi, Victor Mwingira, Robert Malima, Victoria Githu, Brian Masanja, Yeromin Mlacha, Patrick Tungu, Bilali Kabula…
    Citation: Malaria Journal 2024 23:29
  26. In children with cerebral malaria (CM) admission blood lactate has previously guided intravenous fluid therapy and been validated as a prognostic biomarker associated with death. The usefulness of post-admissi...

    Authors: Ronke Olowojesiku, Meredith G. Sherman, Amina M. Mukadam, Rami Imam, Kennedy M. Chastang, Karl B. Seydel, Alice M. Liomba, John R. Barber, Nicole F. O’Brien and Douglas G. Postels
    Citation: Malaria Journal 2024 23:28
  27. Though Plasmodium vivax is the second most common malaria species to infect humans, it has not traditionally been considered a major human health concern in central Africa given the high prevalence of the human D...

    Authors: Valerie Gartner, Benjamin D. Redelings, Claudia Gaither, Jonathan B. Parr, Albert Kalonji, Fernandine Phanzu, Nicholas F. Brazeau, Jonathan J. Juliano and Gregory A. Wray
    Citation: Malaria Journal 2024 23:27
  28. Asymptomatic malaria transmission has become a public health concern across malaria-endemic Africa including Ethiopia. Specifically, Plasmodium vivax is more efficient at transmitting earlier in the infection and...

    Authors: Gemechu Zeleke, Luc Duchateau, Delenasaw Yewhalaw, Sultan Suleman and Mathias Devreese
    Citation: Malaria Journal 2024 23:26
  29. This paper examines the far-reaching implications of Triple Artemisinin-Based Combination Therapy (TACT) in the global battle against malaria. Artemisinin-Based Combination Therapy (ACT) is recognized for its ...

    Authors: Emmanuel Kokori, Gbolahan Olatunji, Adeola Akinboade, Aminat Akinoso, Emmanuel Egbunu, Sikiru Ademola Aremu, Chuka Emmanuel Okafor, Olamide Oluwole and Nicholas Aderinto
    Citation: Malaria Journal 2024 23:25
  30. Malaria outbreaks have sporadically occurred in the United States, with Anopheles quadrimaculatus serving as the primary vector in the eastern region. Anopheles crucians, while considered a competent vector, has ...

    Authors: André B. B. Wilke, Chalmers Vasquez, Johana Medina, Isik Unlu, John C. Beier and Marco Ajelli
    Citation: Malaria Journal 2024 23:24
  31. Different anopheline species (even within a species group/complex) can differ in their feeding and resting behaviours, which impact both malaria transmission patterns as well as the efficacy of vector control ...

    Authors: Mara Máquina, Mercy A. Opiyo, Nelson Cuamba, Dulcisária Marrenjo, Maria Rodrigues, Sarmento Armando, Sheila Nhate, Fabião Luis, Francisco Saúte, Baltazar Candrinho, Neil F. Lobo and Krijn P. Paaijmans
    Citation: Malaria Journal 2024 23:23
  32. Chronic carriage of asymptomatic low-density Plasmodium falciparum parasitaemia in the dry season may support maintenance of acquired immunity that protects against clinical malaria. However, the relationship bet...

    Authors: Balotin Fogang, Lionel Lellouche, Sukai Ceesay, Sainabou Drammeh, Fatou K. Jaiteh, Marc-Antoine Guery, Jordi Landier, Cynthia P. Haanappel, Janeri Froberg, David Conway, Umberto D’Alessandro, Teun Bousema and Antoine Claessens
    Citation: Malaria Journal 2024 23:22
  33. Malaria remains a major public health problem in the Republic of Congo, with Plasmodium falciparum being the deadliest species of Plasmodium in humans. Vector transmission of malaria is poorly studied in the coun...

    Authors: Jacques Dollon Mbama Ntabi, Abel Lissom, Jean Claude Djontu, Francis N. Nkemngo, Steve Diafouka-Kietela, Jolivet Mayela, Georges Missontsa, Luc Djogbenou, Cyrille Ndo, Charles Wondji, Ayola Akim Adegnika, Arsène Lenga, Steffen Borrmann and Francine Ntoumi
    Citation: Malaria Journal 2024 23:21
  34. Malaria remains a major public health problem in sub-Saharan Africa, particularly in Benin. The present study aims to evaluate the different Plasmodium species transmitted by malaria vectors in the communes of Co...

    Authors: Tatchémè Filémon Tokponnon, Razaki Ossè, Boulais Yovogan, Ella Guidi, Constantin J. Adoha, André Sominanhouin, Juvenal Ahouandjinou, Aboubakar Sidick and Martin C. Akogbeto
    Citation: Malaria Journal 2024 23:20
  35. For at least a decade, concerns have been raised about the physical durability of insecticide-treated nets (ITNs) and their ability to remain in good condition for at least three years. To discover if the resi...

    Authors: Amy Wheldrake, Estelle Guillemois, Hamidreza Arouni, Vera Chetty, Edoardo Zappa and Stephen J. Russell
    Citation: Malaria Journal 2024 23:19
  36. Malaria outbreaks are detected by applying the World Health Organization (WHO)-recommended thresholds (the less sensitive 75th percentile or mean + 2 standard deviations [2SD] for medium-to high-transmission a...

    Authors: Marie Gorreti Zalwango, Jane F. Zalwango, Daniel Kadobera, Lilian Bulage, Carol Nanziri, Richard Migisha, Bosco B. Agaba, Benon Kwesiga, Jimmy Opigo, Alex Riolexus Ario and Julie R. Harris
    Citation: Malaria Journal 2024 23:18
  37. Decrease in malaria rates (e.g. incidence and cases) in Latin America maintains this region on track to achieve the goal of elimination. During the last 5 years, three countries have been certified as malaria ...

    Authors: Sebasthian Real-Jaramillo, Juan J. Bustillos, Ana L. Moncayo, Marco Neira, Leonardo Fárez, Efraín Beltrán and Sofía Ocaña-Mayorga
    Citation: Malaria Journal 2024 23:17
  38. Malaria affects millions of lives annually, particularly in tropical and subtropical regions. Despite being largely preventable, 2021 witnessed 247 million infections and over 600,000 deaths across 85 countrie...

    Authors: Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Sodeeq Sikirullahi, John Ehi Aboje and Rebecca Ebokondu Ojabo
    Citation: Malaria Journal 2024 23:16
  39. Recent estimates show progress toward malaria elimination is slowing in many settings, underscoring the need for tailored approaches to fight the disease. In addition to essential structural changes, human beh...

    Authors: Albert Casella, April Monroe, Michael Toso, Gabrielle Hunter, Carol Underwood, Ruchita Pillai, Jayme Hughes, Lynn M. Van Lith, Shelby Cash, Jimee Hwang and Stella Babalola
    Citation: Malaria Journal 2024 23:15
  40. Investigating the species distribution and their role in malaria transmission is important as it varies from place to place and is highly needed to design interventions appropriate to the site. The current stu...

    Authors: Nigatu Eligo, Teklu Wegayehu, Myrthe Pareyn, Girum Tamiru, Bernt Lindtjørn and Fekadu Massebo
    Citation: Malaria Journal 2024 23:14
  41. Plasmodium lacks an mRNA export receptor ortholog, such as yeast Mex67. Yeast Mex67 contains a nuclear transport factor 2 (NTF2)-like domain, suggesting that NTF2-like domain-containing proteins might be associa...

    Authors: Mamoru Niikura, Toshiyuki Fukutomi, Jiro Mitobe and Fumie Kobayashi
    Citation: Malaria Journal 2024 23:13
  42. Clothianidin, an insecticide with a novel mode of action, has been deployed in the annual indoor residual spraying programme in northern Ghana since March 2021. To inform pragmatic management strategies and gu...

    Authors: Cosmos M. Pambit Zong, Sylvester Coleman, Abdul Rahim Mohammed, Christopher M. Owusu-Asenso, Yaw Akuamoah-Boateng, Isaac K. Sraku, Simon K. Attah, Liwang Cui and Yaw A. Afrane
    Citation: Malaria Journal 2024 23:12
  43. Malaria continues to pose a significant health threat. Rapid identification of malaria infections and the deployment of active surveillance tools are crucial for achieving malaria elimination in regions where ...

    Authors: Oraya Srimokla, Wirichada Pan-Ngum, Amnat Khamsiriwatchara, Chantana Padungtod, Rungrawee Tipmontree, Noppon Choosri and Sompob Saralamba
    Citation: Malaria Journal 2024 23:11
  44. Endothelial cells (ECs) play a major role in malaria pathogenesis, as a point of direct contact of parasitized red blood cells to the blood vessel wall. The study of cytoskeleton structures of ECs, whose main ...

    Authors: Mathusorn Wongsawat, Supattra Glaharn, Charit Srisook, Wilanee Dechkhajorn, Urai Chaisri, Chuchard Punsawad, Tachpon Techarang, Kesinee Chotivanich, Srivicha Krudsood and Parnpen Viriyavejakul
    Citation: Malaria Journal 2024 23:10
  45. Decreased efficacy of artemisinin-based combination therapy (ACT) for Plasmodium falciparum malaria has been previously reported in patients with sickle cell disease (SCD). The main purpose of this study was to i...

    Authors: Albert A. Gnondjui, Offianan A. Toure, Berenger A. Ako, Tossea S. Koui, Stanislas E. Assohoun, Eric A. Gbessi, Landry T. N’Guessan, Karim Tuo, Sylvain Beourou, Serge-Brice Assi, Francis A. Yapo, Ibrahima Sanogo and Ronan Jambou
    Citation: Malaria Journal 2024 23:9
  46. Africa and the United States are both large, heterogeneous geographies with a diverse range of ecologies, climates and mosquito species diversity which contribute to disease transmission and nuisance biting. I...

    Authors: Eric Ochomo, Samuel S. C. Rund, Rosheen S. Mthawanji, Christophe Antonio-Nkondjio, Maxwell Machani, Siriman Samake, Rosine Z. Wolie, Sandrine Nsango, Laurel Anne Lown, Damaris Matoke-Muhia, Luna Kamau, Edward Lukyamuzi, Jane Njeri, Joseph Chabi, Otubea Owusu Akrofi, Charles Ntege…
    Citation: Malaria Journal 2024 23:8
  47. In Spain, the risk of imported malaria has increased in recent years due to the rise in international travel and migration. Little is known about the knowledge, information sources, clinical practice, and spec...

    Authors: Manuel Linares-Rufo, Harold Bermudez-Marval, Carlos García-Bertolín, Joaquín Santos-Galilea, Javier Balsa-Vázquez, Ramón Pérez-Tanoira, Laura Santos-Larrégola, Juan Cuadros-González, Gerardo Rojo-Marcos and José-Manuel Ramos-Rincón
    Citation: Malaria Journal 2024 23:7
  48. Approximately 32 million pregnant women are at risk of malaria with up to 10,000 maternal deaths and 200,000 neonates at risk annually. Intermittent Preventive Treatment (IPT) with sulfadoxine-pyrimethamine (S...

    Authors: Sabrina Lynda Simo Kamga, Innocent Mbulli Ali, Ghislain Romeo Ngangnang, Mehmet Can Ulucesme, Leonard T. D. Keptcheu, Eva Mai Keming, Valery-Pacome Kom Tchuenkam, Juluis Visnel Foyet, Münir Aktas, Michel Noubom and Vincent K. Payne
    Citation: Malaria Journal 2024 23:6
  49. Differences between urban and rural contexts in terms of sociodemographic characteristics, geographical features and risk perceptions may lead to disparities in coverage and related outcomes of community-based...

    Authors: Taiwo Ibinaiye, Kunle Rotimi, Ayodeji Balogun, Adaeze Aidenagbon, Chibuzo Oguoma, Kevin Baker, Olabisi Ogunmola, Olusola Oresanya, Christian Rassi and Chuks Nnaji
    Citation: Malaria Journal 2024 23:4

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