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  1. Despite continuous prevention and control strategies in place, malaria remains a major public health problem in sub-Saharan Africa including Ethiopia. Moreover, prevalence of malaria differs in different geogr...

    Authors: Girma Yutura, Fekadu Massebo, Nigatu Eligo, Abena Kochora and Teklu Wegayehu
    Citation: Malaria Journal 2024 23:143
  2. The development of resistance by Plasmodium falciparum is a burdening hazard that continues to undermine the strides made to alleviate malaria. As such, there is an increasing need to find new alternative strateg...

    Authors: Muzi N. Buthelezi, Vhahangwele G. Tshililo, Abidemi P. Kappo and Mthokozisi B. C. Simelane
    Citation: Malaria Journal 2024 23:141
  3. Plasmodium vivax relapses due to dormant liver hypnozoites can be prevented with primaquine. However, the dose must be adjusted in individuals with glucose-6-phosphate-dehydrogenase (G6PD) deficiency. In French G...

    Authors: Laureen Dahuron, Juste Goungounga, Moustapha Drame, Maylis Douine, Mathieu Nacher, Théo Blaise, Emilie Mosnier, Lise Musset, Marie Fouillet, Félix Djossou and Loïc Epelboin
    Citation: Malaria Journal 2024 23:140
  4. In 2021 and 2023, the World Health Organization approved RTS,S/AS01 and R21/Matrix M malaria vaccines, respectively, for routine immunization of children in African countries with moderate to high transmission...

    Authors: Beatus M. Lyimo, Catherine Bakari, Zachary R. Popkin-Hall, David J. Giesbrecht, Misago D. Seth, Dativa Pereus, Zulfa I. Shabani, Ramadhan Moshi, Ruth Boniface, Celine I. Mandara, Rashid Madebe, Jonathan J. Juliano, Jeffrey A. Bailey and Deus S. Ishengoma
    Citation: Malaria Journal 2024 23:139
  5. Artemisinin resistance in Plasmodium falciparum threatens global malaria elimination efforts. To contain and then eliminate artemisinin resistance in Eastern Myanmar a network of community-based malaria posts was...

    Authors: Aung Myint Thu, Aung Pyae Phyo, Chanapat Pateekhum, Jade D. Rae, Jordi Landier, Daniel M. Parker, Gilles Delmas, Wanitda Watthanaworawit, Alistair R. D. McLean, Ann Arya, Ann Reyes, Xue Li, Olivo Miotto, Kyaw Soe, Elizabeth A. Ashley, Arjen Dondorp…
    Citation: Malaria Journal 2024 23:138
  6. Universal coverage with insecticide-treated nets (ITNs) is important for malaria control and elimination. The emergence and intensification of insecticide resistance threatens progress made through the deploym...

    Authors: Jenny Shannon, Moubassira Kagone, Baltazar Candrinho, Sylvanus Otikwu, Chantal Ingabire, Adama Gansane, Samy Pooda, Fofana Aboubacar, Fatou Ouattara, Binete Savaio, Celestino Joanguete, Lucio Sixpence, Hannah Koenker, Perpetua Uhomoibhi, Okefu Oyale Okoko, Onoja Ali…
    Citation: Malaria Journal 2024 23:137
  7. The direct membrane feeding assay (DMFA), whereby gametocyte-infected blood is collected from human donors and from which mosquitoes feed through a membrane, is proving essential for assessing parameters influ...

    Authors: Seydou Bienvenu Ouattara, Domonbabele F. D. S. Hien, Ekôbié T. Nao, Prisca S. L. Paré, Edwige Guissou, Anna Cohuet, Isabelle Morlais, Rakiswendé S. Yerbanga, Kounbobr R. Dabiré, Jean Bosco Ouédraogo, Karine Mouline and Thierry Lefèvre
    Citation: Malaria Journal 2024 23:135
  8. Studies on haemosporidian diversity, including origin of human malaria parasites, malaria's zoonotic dynamic, and regional biodiversity patterns, have used target gene approaches. However, current methods have...

    Authors: M. Andreína Pacheco, Axl S. Cepeda, Erica A. Miller, Scott Beckerman, Mitchell Oswald, Evan London, Nohra E. Mateus-Pinilla and Ananias A. Escalante
    Citation: Malaria Journal 2024 23:134
  9. Drug repurposing offers a strategic alternative to the development of novel compounds, leveraging the known safety and pharmacokinetic profiles of medications, such as linezolid and levofloxacin for tuberculos...

    Authors: Thomas Hanscheid, Claire Ruiz del Portal Luyten, Sabine M. Hermans and Martin P. Grobusch
    Citation: Malaria Journal 2024 23:132
  10. In Nigeria, seasonal malaria chemoprevention (SMC) is typically administered door-to-door to children under five by community medicine distributors during high transmission seasons. While door-to-door distribu...

    Authors: Sikai Huang, Kevin Baker, Taiwo Ibinaiye, Olusola Oresanya, Chuks Nnaji and Sol Richardson
    Citation: Malaria Journal 2024 23:131
  11. The sequestration of Plasmodium falciparum infected erythrocytes in the placenta, and the resulting inflammatory response affects maternal and child health. Despite existing information, little is known about the...

    Authors: Carolina López-Guzmán, Ana María García, Juan Diego Ramirez, Trinidad Torres Aliaga, Alejandro Fernández-Moya, Ulrike Kemmerling and Ana María Vásquez
    Citation: Malaria Journal 2024 23:130
  12. Malaria has remained a persistent global health problem. Despite multiple government and donor initiatives to eradicate malaria and its detrimental effects on Uganda's health outcomes, the incidence of malaria...

    Authors: Jemimah Katushabe, John Bosco Nnyanzi and Gertrude Sebunya Muwanga
    Citation: Malaria Journal 2024 23:129
  13. Malaria treatment in sub-Saharan Africa is faced with challenges including unreliable supply of efficacious agents, substandard medicines coupled with high price of artemisinin-based combinations. This affects...

    Authors: Moses Ocan, Loyce Nakalembe, Caroline Otike, Tayebwa Mordecai, Joan Birungi and Sam Nsobya
    Citation: Malaria Journal 2024 23:128
  14. The decreasing residual efficacy of insecticides is an important factor when making decisions on insecticide choice for national malaria control programmes. The major challenge to using chemicals for vector co...

    Authors: Rajendra Maharaj, Ishen Seocharan, Vishan Lakan, Zuziwe Nyawo, Moses Mkhabela and Yusentha Balakrishna
    Citation: Malaria Journal 2024 23:127
  15. Introduction: Malaria continues to be the leading cause of hospitalization and death in Angola, a country in sub- Saharan Africa. In 2023, in the first quarter, 2,744,682 cases were registered, and of these 2,...

    Authors: Euclides N. M. Sacomboio, Santo D. Zua, Adelino T. Tchivango, António D. Pululu, Adilson C. D. Caumba, Adelina B. M. Paciência, Danilson V. Sati, Sabina G. Agostinho, Yolanda S. Agostinho, Fernando G. Mazanga, Neusa B. Ntambo, Cruz S. Sebastião, Joana P. Paixão and Joana Morais
    Citation: Malaria Journal 2024 23:126
  16. Despite efforts made to reduce morbidity and mortality associated with malaria, especially in sub-Saharan Africa, malaria continues to be a public health concern that requires innovative efforts to reach the W...

    Authors: Nicholas Ekow Thomford, Tracy Kellermann, Robert Peter Biney, Charné Dixon, Samuel Badu Nyarko, Richmond Owusu Ateko, Martins Ekor and George B. Kyei
    Citation: Malaria Journal 2024 23:125
  17. Malaria contributes to excess child mortality in The Gambia. Children under five are at risk of severe malaria and death if not treated promptly and appropriately. It is crucial that a child with fever receive...

    Authors: Laura Arntson, Katherine R. McLaughlin and Ellen Smit
    Citation: Malaria Journal 2024 23:124
  18. Malaria is still a disease of global public health importance and children under-five years of age are the most vulnerable to the disease. Nigeria adopted the “test and treat” strategy in the national malaria ...

    Authors: Mina Whyte, Latifat Ibisomi, Tobias Chirwa, Jonathan Levin and Wiedaad Slemming
    Citation: Malaria Journal 2024 23:123
  19. Anopheles coluzzii is a primary vector of malaria found in West and Central Africa, but its presence has hitherto never been documented in Kenya. A thorough understanding of vector bionomics is important as it en...

    Authors: Luna Kamau, Kelly L. Bennett, Eric Ochomo, Jeremy Herren, Silas Agumba, Samson Otieno, Diana Omoke, Damaris Matoke-Muhia, David Mburu, Joseph Mwangangi, Edith Ramaita, Elijah O. Juma, Charles Mbogo, Sonia Barasa and Alistair Miles
    Citation: Malaria Journal 2024 23:122
  20. In Madagascar, the districts of Antsirabe II, Faratsiho and Antsiranana I have relatively low malaria incidence rates and have been selected by the National Malaria Control Programme for pilot elimination stra...

    Authors: Elisabeth Gebreegziabher, Andry Raoliarison, Andrinirina Ramananjato, Andriamamonjy Fanomezana, Martin Rafaliarisoa, Sandy Ralisata, Jocelyn Razafindrakoto, Jennifer L. Smith, Jehan Ahmed and Cara Smith Gueye
    Citation: Malaria Journal 2024 23:121
  21. The increased availability and use of malaria rapid diagnostic test (RDT) by primary healthcare (PHC) workers has made universal diagnostic testing before malaria treatment more feasible. However, to meaningfu...

    Authors: Ugwu I. Omale
    Citation: Malaria Journal 2024 23:120
  22. The residual activity of a clothianidin + deltamethrin mixture and clothianidin alone in IRS covered more than the period of malaria transmission in northern Benin. The aim of this study was to show whether th...

    Authors: Esdras Mahoutin Odjo, Christian S. T. Akpodji, Armel Djènontin, Albert Sourou Salako, Gil Germain Padonou, Constantin Jésukèdè Adoha, Boulais Yovogan, Bruno Adjottin, Filémon T. Tokponnon, Razaki Osse, Clement Agbangla and Martin C. Akogbeto
    Citation: Malaria Journal 2024 23:119
  23. Authors: Giulia Manzoni, Rady Try, Jean Olivier Guintran, Céline Christiansen-Jucht, Elodie Jacoby, Siv Sovannaroth, Zaixing Zhang, Vilasack Banouvong, Matthew Scott Shortus, Rita Reyburn, Chitsavang Chanthavisouk, Nay Yi Yi Linn, Badri Thapa, San Kyawt Khine, Prayuth Sudathip, Deyer Gopinath…
    Citation: Malaria Journal 2024 23:118

    The original article was published in Malaria Journal 2024 23:64

  24. There are giant steps taken in the introduction of the novel malaria vaccine poised towards reducing mortality and morbidity associated with malaria.

    Authors: Awoere T. Chinawa, Edmund N. Ossai, Vivian O. Onukwuli, Obinna C. Nduagubam, Ndubuisi A. Uwaezuoke, Chinyere N. Okafor and Josephat M. Chinawa
    Citation: Malaria Journal 2024 23:117
  25. The use of fluorescent proteins (FPs) in Plasmodium parasites has been key to understand the biology of this obligate intracellular protozoon. FPs like the green fluorescent protein (GFP) enabled to explore prote...

    Authors: Pia J. Thiele, Raquel Mela-Lopez, Stéphanie A. Blandin and Dennis Klug
    Citation: Malaria Journal 2024 23:114
  26. Microsporidia MB, an endosymbiont naturally found in Anopheles mosquitoes inhibits transmission of Plasmodium and is a promising candidate for a transmission-blocking strategy that may involve mosquito release. A...

    Authors: Tullu Bukhari, Joseph Gichuhi, Oscar Mbare, Victoria A. Ochwal, Ulrike Fillinger and Jeremy K. Herren
    Citation: Malaria Journal 2024 23:113
  27. In malaria endemic regions of the Peruvian Amazon, rainfall together with river level and breeding site availability drive fluctuating vector mosquito abundance and human malaria cases, leading to temporal het...

    Authors: Sara A. Bickersmith, Marlon P. Saavedra, Catharine Prussing, Rachel E. Lange, Juliana A. Morales, Freddy Alava, Joseph M. Vinetz, Dionicia Gamboa, Marta Moreno and Jan E. Conn
    Citation: Malaria Journal 2024 23:112
  28. Sporozoites (SPZ), the infective form of Plasmodium falciparum malaria, can be inoculated into the human host skin by Anopheline mosquitoes. These SPZ migrate at approximately 1 µm/s to find a blood vessel and tr...

    Authors: Roos van Schuijlenburg, Samaneh Azargoshasb, Clarize M. de Korne, Jeroen C. Sijtsma, Sascha Bezemer, Alwin J. van der Ham, Els Baalbergen, Fiona Geurten, Laura M. de Bes-Roeleveld, Severine C. Chevalley-Maurel, Matthias N. van Oosterom, Fijs W. B. van Leeuwen, Blandine Franke-Fayard and Meta Roestenberg
    Citation: Malaria Journal 2024 23:111
  29. Conventional natural killer (cNK) cells play an important role in the innate immune response by directly killing infected and malignant cells and by producing pro- and anti-inflammatory cytokines. Studies on t...

    Authors: Emilie Pollenus, Fran Prenen, Hendrik Possemiers, Sofie Knoops, Tania Mitera, Jochen Lamote, Amber De Visscher, Leen Vandermosten, Thao-Thy Pham, Patrick Matthys and Philippe E. Van den Steen
    Citation: Malaria Journal 2024 23:110
  30. Malaria remains a burden globally, with the African region accounting for 94% of the overall disease burden and deaths in 2019. It is the major cause of morbidity and mortality among children in Nigeria. Thoug...

    Authors: Isaac Isiko, Simon Nyegenye, Daniel Kiprotich Bett, Jackson Micheal Asingwire, Lenz Nwachinemere Okoro, Nana Awaya Emeribe, Catherine Chepkoskei Koech, Ovye Ahgu, Naya Gadzama Bulus, Kelly Taremwa and Aaron Mwesigwa
    Citation: Malaria Journal 2024 23:109
  31. Rapid diagnostic tests (RDTs) play a significant role in expanding case management in peripheral healthcare systems. Histidine-rich protein-2 (HRP2) antigen detection RDTs are predominantly used to diagnose Plasm...

    Authors: Bacha Mekonen, Sisay Dugassa, Sindew Mekasha Feleke, Boja Dufera, Bedasa Gidisa, Aderaw Adamu, Aynalem Mandefro, Geremew Tasew and Lemu Golassa
    Citation: Malaria Journal 2024 23:108
  32. Achieving effective control and elimination of malaria in endemic regions necessitates a comprehensive understanding of local mosquito species responsible for malaria transmission and their susceptibility to i...

    Authors: Gaurav Kumar, Sanjeev Gupta, Jaspreet Kaur, Shweta Pasi, Rajendra Baharia, Ajeet Kumar Mohanty, Pawan Goel, Amit Sharma and Manju Rahi
    Citation: Malaria Journal 2024 23:107
  33. To gain a deeper understanding of protective immunity against relapsing malaria, this study examined sporozoite-specific T cell responses induced by a chemoprophylaxis with sporozoite (CPS) immunization in a r...

    Authors: Kosol Yongvanitchit, Utaiwan Kum-Arb, Amporn Limsalakpetch, Rawiwan Im-Erbsin, Ratawan Ubalee, Michele D. Spring, Brian A. Vesely, Norman Waters and Sathit Pichyangkul
    Citation: Malaria Journal 2024 23:106
  34. Malaria remains a significant global health burden affecting millions of people, children under 5 years and pregnant women being most vulnerable. In 2019, the World Health Organization (WHO) endorsed the intro...

    Authors: Atusaye J. Simbeye, Save Kumwenda, Lauren M. Cohee, Dickens Omondi, Peninah K. Masibo, Hesborn Wao and Shehu S. Awandu
    Citation: Malaria Journal 2024 23:105
  35. While Plasmodium falciparum and Plasmodium vivax cause the majority of malaria cases and deaths, infection by Plasmodium malariae and other Plasmodium species also causes morbidity and mortality. Current understa...

    Authors: Ashenafi Assefa, Kevin Wamae, Christopher M. Hennelly, Billy Ngasala, Meredith Muller, Albert Kalonji, Fernandine Phanzu, Clark H. Cunningham, Jessica T. Lin and Jonathan B. Parr
    Citation: Malaria Journal 2024 23:104
  36. The emergence of resistance to artemisinin-based combination therapy necessitates the search for new, more potent antiplasmodial compounds, including herbal remedies. The whole extract of Maytenus senegalensis ha...

    Authors: Kamaka R. Kassimu, Ali M. Ali, Justin J. Omolo, Abel Mdemu, Francis Machumi and Billy Ngasala
    Citation: Malaria Journal 2024 23:103
  37. Artemisinin-based combination therapy (ACT) has been a major contributor to the substantial reductions in global malaria morbidity and mortality over the last decade. In Tanzania, artemether-lumefantrine (AL) ...

    Authors: Billy E. Ngasala, Mercy G. Chiduo, Bruno P. Mmbando, Filbert T. Francis, Samwel Bushukatale, Twilumba Makene, Celine I. Mandara, Deus S. Ishengoma, Erasmus Kamugisha, Maimuna Ahmed, Muhidin K. Mahende, Reginald A. Kavishe, Florida Muro, Fabrizio Molteni, Erik Reaves, Chonge Kitojo…
    Citation: Malaria Journal 2024 23:101
  38. Anopheles gambiae, the major malaria mosquito in sub-Saharan Africa, feed largely indoors at night. Raising a house off the ground with no barriers underneath reduces mosquito-house entry. This experiment tested ...

    Authors: Majo Carrasco-Tenezaca, Musa Jawara, John Bradley, Umberto D’Alessandro, David Jeffries, Jakob B. Knudsen and Steve W. Lindsay
    Citation: Malaria Journal 2024 23:100
  39. Malaria remains a major global health problem often worsened by political instability and armed conflict. The purpose of the study was to explore community knowledge, attitudes and practices on malaria prevent...

    Authors: Elvis Asangbeng Tanue, Lundi-Anne Omam, Glennis T. Ayuk, Bibiche Modjenpa Noukeme, Alain Metuge, Isabelle Nganmou, Margaret Besem Ebob, Laura Donovan, Ann-Sophie Stratil, Helen Counihan, Claude Ngwayu Nkfusai, Helen Hawkings, Blanka Homolova, Elizabeth Berryman, Maxwell Kolawole, Yakouba Zoungrana…
    Citation: Malaria Journal 2024 23:99
  40. Authors: Chadwick H. Sikaala, Bongani Dlamini, Alphart Lungu, Phelele Fakudze, Mukosha Chisenga, Chishala Lukwesa Siame, Nyasha Mwendera, Dumisani Shaba, John M. Chimumbwa and Immo Kleinschmidt
    Citation: Malaria Journal 2024 23:98

    The original article was published in Malaria Journal 2024 23:62

  41. In sub-Saharan Africa (SSA), Plasmodium falciparum causes most of the malaria cases. Despite its crucial roles in disease severity and drug resistance, comprehensive data on Plasmodium falciparum genetic diversit...

    Authors: Alex Mwesigwa, Moses Ocan, Benson Musinguzi, Rachel Wangi Nante, Joaniter I. Nankabirwa, Steven M. Kiwuwa, Alison Annet Kinengyere, Barbara Castelnuovo, Charles Karamagi, Ekwaro A. Obuku, Samuel L. Nsobya, Sam M. Mbulaiteye and Pauline Byakika-Kibwika
    Citation: Malaria Journal 2024 23:97
  42. Understanding the dynamics of gametocyte production in polyclonal Plasmodium falciparum infections requires a genotyping method that detects distinct gametocyte clones and estimates their relative frequencies. He...

    Authors: Jimmy Vareta, Natalie A. Horstman, Matthew Adams, Karl B. Seydel, Robert S. McCann, Lauren M. Cohee, Miriam K. Laufer and Shannon Takala-Harrison
    Citation: Malaria Journal 2024 23:96
  43. The use of artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated falciparum malaria. Artemether-lumefantrine (AL) is the most widely ado...

    Authors: Billy Ngasala, Mercy G. Chiduo, Samwel Bushukatale, Bruno P. Mmbando, Twilumba Makene, Erasmus Kamugisha, Maimuna Ahmed, Celine I. Mandara, Filbert Francis, Muhidin K. Mahende, Reginald A. Kavishe, Florida Muro, Deus S. Ishengoma, Renata Mandike, Fabrizio Molteni, Frank Chacky…
    Citation: Malaria Journal 2024 23:95
  44. Despite remarkable progress in malaria burden reduction, malaria continues to be a major public health problem globally. Ethiopia has been distributing long-lasting insecticidal nets (LLINs) for free and natio...

    Authors: Misganu Endriyas, Mekidim Kassa, Yilma Chisha, Emebet Mekonnen, Tebeje Misganaw, Eskindir Loha and Ayalew Astatkie
    Citation: Malaria Journal 2024 23:94
  45. Plasmodium ovale malaria is usually considered a tropical infectious disease associated with low morbidity and mortality. However, severe disease and death have previously been reported.

    Authors: Maria Virginia Tomassi, Alessandra D’Abramo, Serena Vita, Angela Corpolongo, Antonella Vulcano, Tommaso Ascoli Bartoli, Barbara Bartolini, Francesca Faraglia and Emanuele Nicastri
    Citation: Malaria Journal 2024 23:93

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