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  1. Immune responses to malaria blood stage infection are in general defective, with the need for long-term exposure to the parasite to achieve immunity, and with the development of immunopathology states such as ...

    Authors: Leonardo JM Carvalho, Maria F Ferreira-da-Cruz, Claudio T Daniel-Ribeiro, Marcelo Pelajo-Machado and Henrique L Lenzi
    Citation: Malaria Journal 2007 6:59
  2. An assessment of the accuracy of Paracheck Pf®, a malaria rapid diagnostic test (RDT) detecting histidine rich protein 2 was undertaken amongst children aged 6–59 months in eastern Democratic Republic of Congo.

    Authors: Todd D Swarthout, Helen Counihan, Raphael Kabangwa K Senga and Ingrid van den Broek
    Citation: Malaria Journal 2007 6:58
  3. Global malaria control strategies highlight the need to increase early uptake of effective antimalarials for childhood fevers in endemic settings, based on a presumptive diagnosis of malaria in this age group....

    Authors: Timothy O Abuya, Wilfred Mutemi, Baya Karisa, Sam A Ochola, Greg Fegan and Vicki Marsh
    Citation: Malaria Journal 2007 6:57
  4. The emergence of Anopheles populations capable of withstanding lethal doses of insecticides has weakened the efficacy of most insecticide based strategies of vector control and, has highlighted the need for devel...

    Authors: Rousseau F Djouaka, Adekunle A Bakare, Honore S Bankole, Julien MC MC Doannio, Hortense Kossou and Martin C Akogbeto
    Citation: Malaria Journal 2007 6:56
  5. Nigeria's national standard has recently moved to artemisinin combination treatments for malaria. As clinicians in the private sector are responsible for attending a large proportion of the population ill with...

    Authors: Martin Meremikwu, Uduak Okomo, Chukwuemeka Nwachukwu, Angela Oyo-Ita, John Eke-Njoku, Joseph Okebe, Esu Oyo-Ita and Paul Garner
    Citation: Malaria Journal 2007 6:55
  6. In the last five years, countries have been faced with changing their malaria treatment policy to an artemisinin-based combination therapy (ACT), many with no national data on which to base their decision. Thi...

    Authors: Maryline Bonnet, Cally Roper, Martine Félix, Léonie Coulibaly, Gabriel Mufuta Kankolongo and Jean Paul Guthmann
    Citation: Malaria Journal 2007 6:54
  7. A comprehensive malaria control intervention was initiated in February 2004 on Bioko Island, Equatorial Guinea. This manuscript reports on the continuous entomological monitoring of the indoor residual spray (...

    Authors: Brian L Sharp, Frances C Ridl, Dayanandan Govender, Jaime Kuklinski and Immo Kleinschmidt
    Citation: Malaria Journal 2007 6:52
  8. Little is known about children undergoing critical care for malaria. The purpose of this survey was to evaluate the outcome in African children requiring endotracheal intubation for life-threatening malaria.

    Authors: Patrick Gérardin, Christophe Rogier, Amadou S Ka, Philippe Jouvencel, Bakary Diatta and Patrick Imbert
    Citation: Malaria Journal 2007 6:51
  9. The origin of highly competent malaria vectors has been linked to productive larval habitats in the field, but there isn't solid quantitative or qualitative data to support it. To test this, the effect of larv...

    Authors: Bernard A Okech, Louis C Gouagna, Guiyun Yan, John I Githure and John C Beier
    Citation: Malaria Journal 2007 6:50
  10. Capacity strengthening of rural communities, and the various actors that support them, is needed to enable them to lead their own malaria control programmes. Here the existing capacity of a rural community in ...

    Authors: Pamela Opiyo, W Richard Mukabana, Ibrahim Kiche, Evan Mathenge, Gerry F Killeen and Ulrike Fillinger
    Citation: Malaria Journal 2007 6:48
  11. Malaria control strategies are designed as a solution for either the whole region or the whole country and are assumed to suit every setting. There is a need to shift from this assumption because transmission ...

    Authors: Yazoumé Yé, Catherine Kyobutungi, Valérie R Louis and Rainer Sauerborn
    Citation: Malaria Journal 2007 6:46
  12. Enolase (2-Phospho-D-glycerate hydrolase; EC 4.2.1.11) is one of the glycolytic enzymes, whose levels are highly elevated in malaria parasite infected red blood cells. In several organisms, enolases have been ...

    Authors: Ipsita Pal-Bhowmick, Hardeep K Vora and Gotam K Jarori
    Citation: Malaria Journal 2007 6:45
  13. The main objective of this study was to assess the influence of gas mixtures on in vitro Plasmodium falciparum growth and 50% inhibitory concentration (IC50) for chloroquine.

    Authors: Sébastien Briolant, Philippe Parola, Thierry Fusaï, Marilyn Madamet-Torrentino, Eric Baret, Joël Mosnier, Jean P Delmont, Daniel Parzy, Philippe Minodier, Christophe Rogier and Bruno Pradines
    Citation: Malaria Journal 2007 6:44
  14. Malaria during first few months of life may be due to transplacental transfer of parasitized maternal erythrocytes. Although IgG and IgM antimalarial antibodies can be detected in maternal blood, only IgG anti...

    Authors: Neena Valecha, Sunita Bhatia, Sadhna Mehta, Sukla Biswas and Aditya P Dash
    Citation: Malaria Journal 2007 6:43
  15. Co-infection with falciparum malaria and leptospirosis is uncommon. The aim of this study is to report a case of severe sepsis secondary to dual infection with falciparum malaria and leptospirosis. The literat...

    Authors: Rajagopala Srinivas, Ritesh Agarwal and Dheeraj Gupta
    Citation: Malaria Journal 2007 6:42
  16. Chloroquine (CQ) has been in use in Africa for a long time. Because of misuse, this drug has now lost its efficacy due to the emergence of resistance strains in most parts of Africa. Recently, it was shown tha...

    Authors: Olusola Ojurongbe, Titus O Ogungbamigbe, Adetayo F Fagbenro-Beyioku, Rolf Fendel, Peter G Kremsner and Jürgen FJ Kun
    Citation: Malaria Journal 2007 6:41
  17. Early recognition of symptoms and signs perceived as malaria are important for effective case management, as few laboratories are available at peripheral health facilities. The validity and reliability of clin...

    Authors: Richard Ndyomugyenyi, Pascal Magnussen and Siân Clarke
    Citation: Malaria Journal 2007 6:39
  18. To manage the kdr pyrethroid-resistance in Anopheline malaria vectors, new compounds or new strategies are urgently needed. Recently, mixing repellents (DEET) and a non-pyrethroid insecticide (propoxur) was shown...

    Authors: Cédric Pennetier, Vincent Corbel, Pélagie Boko, Abibatou Odjo, Raphaël N'Guessan, Bruno Lapied and Jean-Marc Hougard
    Citation: Malaria Journal 2007 6:38
  19. In Cambodia, estimates of the malaria burden rely on a public health information system that does not record cases occurring among remote populations, neither malaria cases treated in the private sector nor as...

    Authors: Sandra Incardona, Sirenda Vong, Lim Chiv, Pharath Lim, Sina Nhem, Rithy Sem, Nimol Khim, Socheat Doung, Odile Mercereau-Puijalon and Thierry Fandeur
    Citation: Malaria Journal 2007 6:37
  20. Plasmodium falciparum is the predominant human malaria species in Mozambique and a lead cause of mortality among children and pregnant women nationwide. Sulphadoxine/pyrimethamine (S/P) is used as first line anti...

    Authors: Natércia Fernandes, Paula Figueiredo, Virgilio E do Rosário and Pedro Cravo
    Citation: Malaria Journal 2007 6:35
  21. Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at the codon 76. Previous stu...

    Authors: Jeana T DaRe, Rajeev K Mehlotra, Pascal Michon, Ivo Mueller, John Reeder, Yagya D Sharma, Mark Stoneking and Peter A Zimmerman
    Citation: Malaria Journal 2007 6:34
  22. Extra-Amazonian autochthonous Plasmodium vivax infections have been reported in mountainous regions surrounded by the Atlantic Forest in Espírito Santo state, Brazil.

    Authors: Crispim Cerutti Junior, Marcos Boulos, Arnídio F Coutinho, Maria do Carmo LD Hatab, Aloísio Falqueto, Helder R Rezende, Ana Maria RC Duarte, William Collins and Rosely S Malafronte
    Citation: Malaria Journal 2007 6:33
  23. Adhesion of Plasmodium-infected red blood cells (iRBC) to different host cells, ranging from endothelial to red blood cells, is associated to malaria pathology. In vitro studies have shown the relevance of CD36 f...

    Authors: Margarida Cunha-Rodrigues, Sílvia Portugal, Maria Febbraio and Maria M Mota
    Citation: Malaria Journal 2007 6:32
  24. Zambia was the first African country to change national antimalarial treatment policy to artemisinin-based combination therapy – artemether-lumefantrine. An evaluation during the early implementation phase rev...

    Authors: Dejan Zurovac, Mickey Ndhlovu, Nawa Sipilanyambe, Pascalina Chanda, Davidson H Hamer, Jon L Simon and Robert W Snow
    Citation: Malaria Journal 2007 6:31
  25. Insecticide resistance in malaria vector mosquitoes presents a serious problem for those involved in control of this disease. South Africa experienced a severe malaria epidemic during 1999/2000 due to pyrethro...

    Authors: Joel C Mouatcho, Keith Hargreaves, Lizette L Koekemoer, Basil D Brooke, Shüne V Oliver, Richard H Hunt and Maureen Coetzee
    Citation: Malaria Journal 2007 6:30
  26. Artesunate-amodiaquine combination for the treatment of childhood malaria is one of the artemisinin combination therapies (ACTs) recommended by National authorities in many African countries today. Effectivene...

    Authors: Sunny Oyakhirome, Marc Pötschke, Norbert G Schwarz, Jenny Dörnemann, Matthias Laengin, Carmen Ospina Salazar, Bertrand Lell, Jürgen FJ Kun, Peter G Kremsner and Martin P Grobusch
    Citation: Malaria Journal 2007 6:29
  27. Single nucleotide polymorphisms (SNPs) in the Plasmodium vivax dihydrofolate reductase (Pfdhfr) and dihydropteroate synthetase (Pvdhps) genes cause parasite resistance to the antifolate drug combination, sulphado...

    Authors: Mette L Schousboe, Rupika S Rajakaruna, Ali Salanti, Hapuarachchige C Hapuarachchi, Gawrie NL Galappaththy, Ib C Bygbjerg, Priyanie H Amerasinghe, Flemming Konradsen and Michael Alifrangis
    Citation: Malaria Journal 2007 6:28
  28. In areas of stable transmission, malaria during pregnancy is associated with severe maternal and foetal outcomes, especially low birth weight (LBW). To prevent these complications, weekly chloroquine (CQ) chem...

    Authors: Lise Denoeud, Nadine Fievet, Agnès Aubouy, Paul Ayemonna, Richard Kiniffo, Achille Massougbodji and Michel Cot
    Citation: Malaria Journal 2007 6:27
  29. Identification of Anopheles gambiae s.s. and Anopheles arabiensis from field-collected Anopheles gambiae s.l. is often necessary in basic and applied research, and in operational control programmes. The currently...

    Authors: Edward D Walker, Alisha R Thibault, Annette P Thelen, Blair A Bullard, Juan Huang, Maurice R Odiere, Nabie M Bayoh, Elizabeth E Wilkins and John M Vulule
    Citation: Malaria Journal 2007 6:23
  30. The presence of counterfeits and sub-standards in African medicines market is a dramatic problem that causes many deaths each year. The increase of the phenomenon of pharmaceutical counterfeiting is due to the...

    Authors: Maria Cristina Gaudiano, Anna Di Maggio, Emilia Cocchieri, Eleonora Antoniella, Paola Bertocchi, Stefano Alimonti and Luisa Valvo
    Citation: Malaria Journal 2007 6:22
  31. Malaria remains a leading cause of morbidity, mortality and non-fatal disability in Zambia, especially among children, pregnant women and the poor. Data gathered by the National Malaria Control Centre has show...

    Authors: Pascalina Chanda, Felix Masiye, Bona M Chitah, Naawa Sipilanyambe, Moonga Hawela, Patrick Banda and Tuoyo Okorosobo
    Citation: Malaria Journal 2007 6:21
  32. The methods most commonly used to measure malarial antibody titres are the Indirect Fluorescence Antibody Test (IFAT), regarded as the gold standard, and the Enzyme-Linked ImmunoSorbent Assay (ELISA). The obje...

    Authors: Cecile Doderer, Aurelie Heschung, Phillippe Guntz, Jean-Pierre Cazenave, Yves Hansmann, Alexandre Senegas, Alexander W Pfaff, Tamer Abdelrahman and Ermanno Candolfi
    Citation: Malaria Journal 2007 6:19
  33. Malaria is a former endemic problem in the Camargue, South East France, an area from where very few recent data concerning Anopheles are available. A study was undertaken in 2005 to establish potential malaria ve...

    Authors: Nicolas Ponçon, Céline Toty, Grégory L'Ambert, Gilbert Le Goff, Cécile Brengues, Francis Schaffner and Didier Fontenille
    Citation: Malaria Journal 2007 6:18
  34. Open access to databases of information generated by the research community can synergize individual efforts and are epitomized by the genome mapping projects. Open source models for outputs of scientific rese...

    Authors: Carlos A Guerra, Simon I Hay, Lorena S Lucioparedes, Priscilla W Gikandi, Andrew J Tatem, Abdisalan M Noor and Robert W Snow
    Citation: Malaria Journal 2007 6:17
  35. Falciparum malaria is an important cause of maternal, perinatal and neonatal morbidity in high transmission settings in Sub-Saharan Africa. Intermittent preventive treatment with sulphadoxine-pyrimethamine (SP...

    Authors: Andrew Vallely, Lisa Vallely, John Changalucha, Brian Greenwood and Daniel Chandramohan
    Citation: Malaria Journal 2007 6:16
  36. An increasing number of countries in sub-Saharan Africa are changing to artemisinins combination therapy (ACT) as first or second line treatment for malaria. There is an urgent need to assess the safety of the...

    Authors: Stephanie Dellicour, Susan Hall, Daniel Chandramohan and Brian Greenwood
    Citation: Malaria Journal 2007 6:15
  37. Coverage of vulnerable groups with insecticide-treated nets (ITNs) in Ghana, as in the majority of countries of sub-Saharan Africa is currently low. A voucher scheme was introduced in Volta Region as a possibl...

    Authors: Margaret Kweku, Jayne Webster, Ian Taylor, Susan Burns and McDamien Dedzo
    Citation: Malaria Journal 2007 6:14
  38. An ITN intervention was initiated in three predominantly rural districts of Eastern Province, Zambia, that lacked commercial distribution and communication infrastructures. Social marketing techniques were use...

    Authors: Sohail Agha, Ronan Van Rossem, Guy Stallworthy and Thankian Kusanthan
    Citation: Malaria Journal 2007 6:13
  39. Artemisinin-derivative formulations are now widely used to treat falciparum malaria. However, the dry powder suspensions developed for children are few and/or are of poor quality. In addition to the active com...

    Authors: Magnus A Atemnkeng, Katelijne De Cock and Jacqueline Plaizier-Vercammen
    Citation: Malaria Journal 2007 6:12
  40. Uganda was the first country to scale up Home Based Management of Fever/Malaria (HBM) in 2002. Under HBM pre-packaged unit doses with a combination Sulphadoxine/Pyrimethamin (SP) and Chloroquine (CQ) called "H...

    Authors: Xavier Nsabagasani, Jesca-Nsungwa-Sabiiti, Karin Källander, Stefan Peterson, George Pariyo and Göran Tomson
    Citation: Malaria Journal 2007 6:11
  41. Insecticide Treated Nets (ITNs) are an important tool for malaria control. ITNs are effective because they work on several parts of the mosquito feeding cycle, including both adult killing and repelling effects.

    Authors: Arnaud Le Menach, Shannon Takala, F Ellis McKenzie, Andre Perisse, Anthony Harris, Antoine Flahault and David L Smith
    Citation: Malaria Journal 2007 6:10

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