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  1. Content type: Research

    Long-lasting insecticidal nets (LLINs) are one of the main vector control strategies recommended by the World Health Organization for the control and elimination of malaria. This study aimed to evaluate the us...

    Authors: Jessica de Oliveira Sousa, Bernardino Claudio de Albuquerque, José Rodrigues Coura and Martha Cecilia Suárez-Mutis

    Citation: Malaria Journal 2019 18:100

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    The Correction to this article has been published in Malaria Journal 2019 18:125

  2. Content type: Research

    The Tanzanian National Malaria Control Programme (NMCP) and its partners have been implementing regular therapeutic efficacy studies (TES) to monitor the performance of different drugs used or with potential u...

    Authors: Celine I. Mandara, Filbert Francis, Mercy G. Chiduo, Billy Ngasala, Renata Mandike, Sigsbert Mkude, Frank Chacky, Fabrizio Molteni, Ritha Njau, Ally Mohamed, Marian Warsame and Deus S. Ishengoma

    Citation: Malaria Journal 2019 18:99

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  3. Content type: Research

    Microscopic detection of malaria parasites is the standard method for clinical diagnosis of malaria in Brazil. However, malaria epidemiological surveillance studies specifically aimed at the detection of low-d...

    Authors: Heather M. Kudyba, Jaime Louzada, Dragan Ljolje, Karl A. Kudyba, Vasant Muralidharan, Joseli Oliveira-Ferreira and Naomi W. Lucchi

    Citation: Malaria Journal 2019 18:98

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  4. Content type: Research

    Lactic acidosis with an elevated lactate–pyruvate ratio suggesting anoxia is a common feature of severe falciparum malaria. High lactate levels are associated with parasitized erythrocyte sequestration in the ...

    Authors: Hugh W. Kingston, Aniruddha Ghose, Voravut Rungpradubvong, M. Trent Herdman, Katherine Plewes, Haruhiko Ishioka, Stije J. Leopold, Richard J. Maude, Benjamas Intharabut, Sanjib Mohanty, Nicholas P. J. Day, Nicholas J. White, Md Amir Hossain, Nicholas M. Anstey and Arjen M. Dondorp

    Citation: Malaria Journal 2019 18:97

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  5. Content type: Research

    Community composition of Anopheles mosquitoes, and their host-seeking and peridomestic behaviour, are important factors affecting malaria transmission. In this study, barrier screen sampling was used to investiga...

    Authors: John B. Keven, Michelle Katusele, Rebecca Vinit, Gussy Koimbu, Naomi Vincent, Edward K. Thomsen, Stephan Karl, Lisa J. Reimer and Edward D. Walker

    Citation: Malaria Journal 2019 18:96

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  6. Content type: Research

    Malaria control in Panama is problematic due to the high diversity of morphologically similar Anopheles mosquito species, which makes identification of vectors of human Plasmodium challenging. Strategies by Panam...

    Authors: Jose R. Loaiza, Alejandro Almanza, Juan C. Rojas, Luis Mejía, Norma D. Cervantes, Javier E. Sanchez-Galan, Fernando Merchán, Arnaud Grillet, Matthew J. Miller, Luis F. De León and Rolando A. Gittens

    Citation: Malaria Journal 2019 18:95

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  7. Content type: Review

    Great progress has been made in recent years to reduce the high level of suffering caused by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria prevention and the use of artem...

    Authors: Edwin G. Tse, Marat Korsik and Matthew H. Todd

    Citation: Malaria Journal 2019 18:93

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  8. Content type: Research

    Adequate knowledge of malaria prevention and control can help in reducing the growing burden of malaria among vulnerable groups, particularly pregnant women and children aged under 5 years living in malaria en...

    Authors: Kelechi Elizabeth Oladimeji, Joyce Mahlako Tsoka-Gwegweni, Elizabeth Ojewole and Samuel Tassi Yunga

    Citation: Malaria Journal 2019 18:92

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  9. Content type: Research

    In April 2017, Suriname’s Ministry of Health alerted French Guiana’s Regional Health Agency (RHA) about an increase of imported malaria cases among people coming from an illegal gold mining site called Sophie, in...

    Authors: Maylis Douine, Alice Sanna, Helene Hiwat, Sébastien Briolant, Mathieu Nacher, Didier Belleoud, François Michel Le Tourneau, Hervé Bogreau and Franck De Laval

    Citation: Malaria Journal 2019 18:91

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  10. Content type: Meeting report

    The Demographic and Health Surveys (DHS) Program has supported three household Malaria Indicator Surveys (MIS) in Madagascar. The results of 13 key malaria indicators from these surveys have been mapped as con...

    Authors: Rosalind E. Howes, Kaleem Hawa, Voahangy Fanomezana Andriamamonjy, Thierry Franchard, Raharizo Miarimbola, Sedera Aurélien Mioramalala, Jean Florent Rafamatanantsoa, Mirana Ando Mbolatiana Rahantamalala, Solo Harimalala Rajaobary, Hariniaina David Gaël Rajaonera, Andrianiaina Parfait Rakotonindrainy, Clairaut Rakotoson Andrianjatonavalona, Dina Ny Aina Liantsoa Randriamiarinjatovo, Faratiana Michèle Randrianasolo, Rado Malalatiana Ramasy Razafindratovo, Masiarivony Ravaoarimanga…

    Citation: Malaria Journal 2019 18:90

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  11. Content type: Research

    Malaria is one of the most prevalent tropical infectious diseases. Since recently cases of artemisinin resistance were reported, novel anti-malarial drugs are required which differ from artemisinins in structu...

    Authors: Andreas Masch, Abed Nasereddin, Arne Alder, Megan J. Bird, Sandra I. Schweda, Lutz Preu, Christian Doerig, Ron Dzikowski, Tim W. Gilberger and Conrad Kunick

    Citation: Malaria Journal 2019 18:89

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  12. Content type: Research

    The World Health Organization recommends regular therapeutic efficacy studies (TES) to monitor the performance of first and second-line anti-malarials. In 2016, efficacy and safety of artemether-lumefantrine (...

    Authors: Deus S. Ishengoma, Celine I. Mandara, Filbert Francis, Eldin Talundzic, Naomi W. Lucchi, Billy Ngasala, Abdunoor M. Kabanywanyi, Muhidin K. Mahende, Erasmus Kamugisha, Reginald A. Kavishe, Florida Muro, Ally Mohamed, Renata Mandike, Sigsbert Mkude, Frank Chacky, Lynn Paxton…

    Citation: Malaria Journal 2019 18:88

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  13. Content type: Research

    Push–pull strategies have been proposed as options to complement primary malaria prevention tools, indoor residual spraying (IRS) and long-lasting insecticide-treated nets (LLINs), by targeting particularly ea...

    Authors: Arnold S. Mmbando, Elis P. A. Batista, Masoud Kilalangongono, Marceline F. Finda, Emmanuel P. Mwanga, Emmanuel W. Kaindoa, Khamis Kifungo, Rukiyah M. Njalambaha, Halfan S. Ngowo, Alvaro E. Eiras and Fredros O. Okumu

    Citation: Malaria Journal 2019 18:87

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  14. Content type: Research

    The malarial parasite Plasmodium falciparum is an auxotroph for purines, which are required for nucleic acid synthesis during the intra-erythrocytic developmental cycle (IDC) of the parasite. The capabilities of ...

    Authors: Shivendra G. Tewari, Krithika Rajaram, Patric Schyman, Russell Swift, Jaques Reifman, Sean T. Prigge and Anders Wallqvist

    Citation: Malaria Journal 2019 18:86

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  15. Content type: Methodology

    Large-scale surveillance of mosquito populations is crucial to assess the intensity of vector-borne disease transmission and the impact of control interventions. However, there is a lack of accurate, cost-effe...

    Authors: Marta F. Maia, Melissa Kapulu, Michelle Muthui, Martin G. Wagah, Heather M. Ferguson, Floyd E. Dowell, Francesco Baldini and Lisa Ranford-Cartwright

    Citation: Malaria Journal 2019 18:85

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    The Correction to this article has been published in Malaria Journal 2019 18:137

  16. Content type: Research

    Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection...

    Authors: Joseph Fulakeza, Sarah McNitt, Jimmy Vareta, Alex Saidi, Godfrey Mvula, Terrie Taylor, Don P. Mathanga, Dylan S. Small, Jacek Skarbinski, Julie R. Gutman and Karl Seydel

    Citation: Malaria Journal 2019 18:84

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  17. Content type: Research

    Mosquito biting rates and host preferences are crucial determinants of human exposure to vector-borne diseases and the impact of vector control measures. The human landing catch (HLC) is a gold standard method...

    Authors: Felician C. Meza, Katharina S. Kreppel, Deodatus F. Maliti, Amos T. Mlwale, Nosrat Mirzai, Gerry F. Killeen, Heather M. Ferguson and Nicodem J. Govella

    Citation: Malaria Journal 2019 18:83

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  18. Content type: Research

    Bayesian methods have been used to generate country-level and global maps of malaria prevalence. With increasing availability of detailed malaria surveillance data, these methodologies can also be used to ide...

    Authors: Punam Amratia, Paul Psychas, Benjamin Abuaku, Collins Ahorlu, Justin Millar, Samuel Oppong, Kwadwo Koram and Denis Valle

    Citation: Malaria Journal 2019 18:81

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  19. Content type: Research

    Comprehensive reports of malaria in Menoreh Hills, Central Java, Indonesia, a unique district cross-boundaries area under three districts and two provinces have been published previously. However, no study was...

    Authors: Dwi Sarwani Sri Rejeki, Anis Fuad, Barandi Sapta Widartono, E. Elsa Herdiana Murhandarwati and Hari Kusnanto

    Citation: Malaria Journal 2019 18:80

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  20. Content type: Research

    Insecticide-treated bed nets (ITNs) help to control malaria by mechanically impeding the biting of mosquitoes, by repelling and irritating them and by killing them. In contrast to spatial repellency, irritancy...

    Authors: Kevin Thiévent, Gaël Hauser, Obada Elaian and Jacob C. Koella

    Citation: Malaria Journal 2019 18:79

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  21. Content type: Research

    The Plasmodium falciparum histidine-rich protein II (PfHRP2) is a common biomarker used in malaria rapid diagnostic tests (RDTs), but can persist in the blood for up to 40 days following curative treatment. The p...

    Authors: Kristin E. Poti, Amanda E. Balaban, Priya Pal, Tamaki Kobayashi, Daniel E. Goldberg, Photini Sinnis and David J. Sullivan

    Citation: Malaria Journal 2019 18:78

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  22. Content type: Research

    Chloroquine, a previous highly efficacious, easy to use and affordable anti-malarial agent was withdrawn from malaria endemic regions due to high levels of resistance. This review collated evidence from publis...

    Authors: Moses Ocan, Dickens Akena, Sam Nsobya, Moses R. Kamya, Richard Senono, Alison Annet Kinengyere and Ekwaro A. Obuku

    Citation: Malaria Journal 2019 18:76

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  23. Content type: Research

    Primaquine is effective against the latent liver stage of Plasmodium vivax. Eliminating the latent liver stage of P. vivax is one of the necessary conditions to achieve the goal of malaria elimination in Lao Peop...

    Authors: Ken Ing Cherng Ong, Moritoshi Iwagami, Hitomi Araki, Phonepadith Khattignavong, Pheovaly Soundala, Sengdeuane Keomalaphet, Phoyphaylinh Prasayasith, Lavy Lorpachan, Phonepadith Xangsayalath, Tiengkham Pongvongsa, Bouasy Hongvanthong, Paul T. Brey, Shigeyuki Kano and Masamine Jimba

    Citation: Malaria Journal 2019 18:75

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  24. Content type: Research

    Previous studies have documented a spectrum of brain magnetic resonance imaging (MRI) abnormalities in patients with cerebral malaria, but little is known about the prevalence of such abnormalities in patients...

    Authors: Andreas M. Frölich, Pinkus Tober-Lau, Michael Schönfeld, Thomas T. Brehm, Florian Kurth, Christof D. Vinnemeier, Marylyn M. Addo, Jens Fiehler and Thierry Rolling

    Citation: Malaria Journal 2019 18:74

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  25. Content type: Research

    Accurate diagnosis of malaria is important for effective disease management and control. In Cameroon, presumptive clinical diagnosis, thick-film microscopy (TFM), and rapid diagnostic tests (RDT) are commonly ...

    Authors: Kenji O. Mfuh, Olivia A. Achonduh-Atijegbe, Obase N. Bekindaka, Livo F. Esemu, Calixt D. Mbakop, Krupa Gandhi, Rose G. F. Leke, Diane W. Taylor and Vivek R. Nerurkar

    Citation: Malaria Journal 2019 18:73

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  26. Content type: Research

    Bio-efficacy and residual activity of SumiShield® 50WG (50%, w/w) with active ingredient clothianidin, a neonicotinoid compound, was assessed using an insecticide-susceptible laboratory strain of Anopheles arabie...

    Authors: Leonard M. Ngwej, Izak Hattingh, Godwill Mlambo, Emmanuel M. Mashat, Jean-Christophe K. Kashala, Françoise K. Malonga and Michael J. Bangs

    Citation: Malaria Journal 2019 18:72

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  27. Content type: Research

    The use of larval source management as a supplementary intervention for malaria control has not been widely used in rural Africa due to perceived high costs and complex logistics. To reduce the cost of larvici...

    Authors: Humphrey D. Mazigo, Isolide S. Massawe, Susan F. Rumisha, Eliningaya J. Kweka and Leonard E. G. Mboera

    Citation: Malaria Journal 2019 18:71

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  28. Content type: Review

    While significant advances have been made in understanding Plasmodium falciparum gametocyte biology and its relationship with malaria parasite transmission, the gametocyte sex ratio contribution to this process s...

    Authors: Noëlie Béré Henry, Samuel Sindié Sermé, Giulia Siciliano, Salif Sombié, Amidou Diarra, N’fale Sagnon, Alfred S. Traoré, Sodiomon Bienvenu Sirima, Issiaka Soulama and Pietro Alano

    Citation: Malaria Journal 2019 18:70

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  29. Content type: Research

    Immunity that limits malarial disease is acquired over time, but adults living in endemic areas continue to become infected and can require treatment for clinical illness. Gamma delta (γδ) T cells, particularl...

    Authors: Hama Diallo, Abdoulaye Katile, Jennifer L. Kwan, Mahamadou S. Sissoko, Sara A. Healy, Ogobara K. Doumbo, Patrick E. Duffy and Irfan Zaidi

    Citation: Malaria Journal 2019 18:69

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  30. Content type: Research

    In some African cities, urban malaria is a threat to the health and welfare of city dwellers. To improve the control of the disease, it is critical to identify neighbourhoods where the risk of malaria transmis...

    Authors: Dipomin F. Traoré, André B. Sagna, Akré M. Adja, Dounin D. Zoh, Kouassi A. Adou, Kouassi N. Lingué, Issa Coulibaly, N’Cho Bertin Tchiekoi, Serge B. Assi, Anne Poinsignon, Mamadou Dagnogo and Franck Remoue

    Citation: Malaria Journal 2019 18:68

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  31. Content type: Research

    Malaria remains a major challenge in sub-Saharan Africa and Ghana is not an exception. Effective malaria transmission control requires evidence-based targeting and utilization of resources. Disease risk mappin...

    Authors: Robert Yankson, Evelyn Arthur Anto and Michael Give Chipeta

    Citation: Malaria Journal 2019 18:67

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  32. Content type: Review

    Plasmodium knowlesi is a zoonotic malaria parasite normally residing in long-tailed and pig-tailed macaques (Macaca fascicularis and Macaca nemestrina, respectively) found throughout Southeast Asia. Recently, kno...

    Authors: Gael Davidson, Tock H. Chua, Angus Cook, Peter Speldewinde and Philip Weinstein

    Citation: Malaria Journal 2019 18:66

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  33. Content type: Research

    Optimal adoption of the malaria transmission-blocking strategy is currently limited by lack of safe and efficacious drugs. This has sparked the exploration of different sources of drugs in search of transmissi...

    Authors: Phanankosi Moyo, Phaladi Kunyane, Mamoalosi A. Selepe, Jacobus N. Eloff, Jandeli Niemand, Abraham I. Louw, Vinesh J. Maharaj and Lyn-Marie Birkholtz

    Citation: Malaria Journal 2019 18:65

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  34. Content type: Research

    Malaria is heterogeneously distributed across landscapes. Human population movement (HPM) could link sub-regions with varying levels of transmission, leading to the persistence of disease even in very low tran...

    Authors: Sayambhu Saita, Wirichada Pan-ngum, Suparat Phuanukoonnon, Patchara Sriwichai, Tassanee Silawan, Lisa J. White and Daniel M. Parker

    Citation: Malaria Journal 2019 18:64

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  35. Content type: Research

    UDP-glycosyltransferase (UGT) is an important biotransformation superfamily of enzymes. They catalyze the transfer of glycosyl residues from activated nucleotide sugars to acceptor hydrophobic molecules, and f...

    Authors: Yong Zhou, Wen-Bo Fu, Feng-Ling Si, Zhen-Tian Yan, Yu-Juan Zhang, Qi-Yi He and Bin Chen

    Citation: Malaria Journal 2019 18:62

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  36. Content type: Research

    Malaria is among the top causes of mortality and morbidity in Zambia. Efforts to control, prevent, and eliminate it have been intensified in the past two decades which has contributed to reductions in malaria ...

    Authors: Mukumbuta Nawa, Peter Hangoma, Andrew P. Morse and Charles Michelo

    Citation: Malaria Journal 2019 18:61

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  37. Content type: Research

    Efficacy of artemisinin (ART) agents, a critical element of current malaria control efforts is threatened by emergence and spread of resistance. Mutations in pfkelch13 gene associated with ART-resistance evolved ...

    Authors: Moses Ocan, Dickens Akena, Sam Nsobya, Moses R. Kamya, Richard Senono, Alison Annet Kinengyere and Ekwaro Obuku

    Citation: Malaria Journal 2019 18:60

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  38. Content type: Research

    MAGNet LN is a wash resistant long-lasting insecticidal (polyethylene) net (LLIN) in which the alpha-cypermethrin insecticide is incorporated within the 150 denier high density polyethylene monofilaments of th...

    Authors: Gunasekaran Kasinathan, Sudhansu Sekhar Sahu, Vijayakumar Tharmalingam, Subramanian Swaminathan, Manju Rahi and Jambulingam Purushothaman

    Citation: Malaria Journal 2019 18:59

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  39. Content type: Case report

    Malarial acute renal failure (MARF) is a component of the severe malaria syndrome, and complicates 1–5% of malaria infections. This form of renal failure has not been well characterized by histopathology.

    Authors: Patrick J. Gleeson, John A. O’Regan, Teresa McHale, Helen Tuite, Louise Giblin and Donal Reddan

    Citation: Malaria Journal 2019 18:58

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  40. Content type: Research

    Malaria transmission-blocking anti-malarial drugs, such as primaquine, offers an effective strategy for reducing the incidence of falciparum malaria. However, this drug induces haemolytic anaemia among glucose...

    Authors: Nerly Shirère Gampio Gueye, Simon Marie Peko, David Nderu, Felix Koukouikila-Koussounda, Christevy Vouvoungui, Simon Charles Kobawila, Thirumalaisamy P. Velavan and Francine Ntoumi

    Citation: Malaria Journal 2019 18:57

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  41. Content type: Research

    Targeting swarms of male Anopheles mosquitoes with techniques such as aerosol spraying could potentially suppress malaria vector populations and parasite transmission. Unfortunately, research on Anopheles swarmin...

    Authors: Marceline F. Finda, Emmanuel W. Kaindoa, Anna P. Nyoni and Fredros O. Okumu

    Citation: Malaria Journal 2019 18:56

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  42. Content type: Research

    Biotic and abiotic factors have been reported to affect the larvicidal efficacy of Bacillus thuringiensis israelensis (Bti) and Bacillus sphaericus (Bs), although the extent to which they are affected has been po...

    Authors: Barnabas Zogo, Bertin N’Cho Tchiekoi, Alphonsine A. Koffi, Amal Dahounto, Ludovic P. Ahoua Alou, Roch K. Dabiré, Lamine Baba-Moussa, Nicolas Moiroux and Cédric Pennetier

    Citation: Malaria Journal 2019 18:55

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  43. Content type: Research

    A growing body of evidence suggests that dams intensify malaria transmission in sub-Saharan Africa. However, the environmental characteristics underpinning patterns in malaria transmission around dams are poor...

    Authors: Solomon Kibret, G. Glenn Wilson, Darren Ryder, Habte Tekie and Beyene Petros

    Citation: Malaria Journal 2019 18:54

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  44. Content type: Research

    Malaria is one of the most severe public health issues that result in massive morbidity and mortality in most countries of the sub-Saharan Africa (SSA). This study aimed to determine the scope of household, ac...

    Authors: Nlandu Roger Ngatu, Sakiko Kanbara, Andre Renzaho, Roger Wumba, Etongola P. Mbelambela, Sifa M. J. Muchanga, Basilua Andre Muzembo, Ngombe Leon-Kabamba, Choomplang Nattadech, Tomoko Suzuki, Numbi Oscar-Luboya, Koji Wada, Mitsunori Ikeda, Sayumi Nojima, Tomohiko Sugishita and Shunya Ikeda

    Citation: Malaria Journal 2019 18:53

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  45. Content type: Research

    Insecticide-based interventions play an integral role in malaria vector control. However, the continued spread of insecticide resistance threatens to undermine progress made thus far and may ultimately lead to...

    Authors: Kendra Dagg, Seth Irish, Ryan E. Wiegand, Josephat Shililu, Delenasaw Yewhalaw and Louisa A. Messenger

    Citation: Malaria Journal 2019 18:49

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