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  1. The primary antibody (Ab) response to Plasmodium falciparum is a critical step in developing immunity to malaria. Information on the initial Ab responses of babies in malaria-endemic areas is incomplete, in part,...

    Authors: Samuel Tassi Yunga, Chathura Siriwardhana, Genevieve G. Fouda, Naveen Bobbili, Grace Sama, John J. Chen, Rose F. G. Leke and Diane Wallace Taylor
    Citation: Malaria Journal 2022 21:346
  2. Current efforts to estimate the spatially diverse malaria burden in malaria-endemic countries largely involve the use of epidemiological modelling methods for describing temporal and spatial heterogeneity usin...

    Authors: Sumaiyya G. Thawer, Monica Golumbeanu, Khalifa Munisi, Sijenunu Aaron, Frank Chacky, Samwel Lazaro, Ally Mohamed, Noela Kisoka, Christian Lengeler, Fabrizio Molteni, Amanda Ross, Robert W. Snow and Emilie Pothin
    Citation: Malaria Journal 2022 21:345
  3. Malaria burden among under-five children living in endemic areas of Yemen is largely unknown due to the lack of community-based studies. Therefore, this study determined the prevalence and risk factors associa...

    Authors: Mona A. A. Al-Quhaiti, Rashad Abdul-Ghani, Mohammed A. K. Mahdy and Methaq A. Assada
    Citation: Malaria Journal 2022 21:344
  4. The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsi...

    Authors: Bárbara Aparecida Chaves, Denise Anete Madureira de Alvarenga, Matheus de Oliveira Costa Pereira, Marcelo Gordo, Emanuelle L. Da Silva, Edson Rodrigues Costa, Aline Souza de Menezes Medeiros, Igor José Martins Pedrosa, Daniela Brito, Maurício Teixeira Lima, Maria Paula Mourão, Wuelton M. Monteiro, Nikos Vasilakis, Cristiana Ferreira Alves de Brito, Gisely C. Melo and Marcus V. G. Lacerda
    Citation: Malaria Journal 2022 21:343
  5. Inducible expression of heme oxygenase-1 (encoded by the gene HMOX1) may determine protection from heme released during malaria infections. A variable length, short tandem GT(n) repeat (STR) in HMOX1 that may inf...

    Authors: Fergus Hamilton, Ruth Mitchell, Aubrey Cunnington, Peter Ghazal and Nicholas J. Timpson
    Citation: Malaria Journal 2022 21:342
  6. Low-density malaria infections (LDMI) are defined as infections that are missed by the rapid diagnostic test (RDT) and/or microscopy which can lead to continued transmission and poses a challenge in malaria el...

    Authors: Akansha Singh, Mrigendra P. Singh, Sneha Bhandari, Harsh Rajvanshi, Sekh Nisar, Vinay Telasey, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur, Altaf A. Lal and Praveen K. Bharti
    Citation: Malaria Journal 2022 21:341
  7. Haemoglobinopathies and G6PD deficiency are inherited disorders found mostly in malaria-endemic areas among different tribal groups of India. However, epidemiological data specific to Particularly Vulnerable T...

    Authors: Sujata Dixit, Arundhuti Das, Ramakanta Rana, Hemant K. Khuntia, Akhil B. Ota, Sanghamitra Pati, Madhusmita Bal and Manoranjan Ranjit
    Citation: Malaria Journal 2022 21:340
  8. The Malaria Vaccine Implementation Programme (MVIP) coordinates the routine implementation of the RTS,S vaccine pilot in strategically selected locations in Malawi, Kenya, and Ghana. The pilot programme thorou...

    Authors: Dominic Yeboah, Joseph Owusu-Marfo and Yaa Nyarko Agyeman
    Citation: Malaria Journal 2022 21:339
  9. Globally, malaria is among the leading cause of under-five mortality and morbidity. Despite various malaria elimination strategies being implemented in the last decades, malaria remains a major public health c...

    Authors: Gebeyaw Biset, Abay Woday Tadess, Kirubel Dagnaw Tegegne, Lehulu Tilahun and Natnael Atnafu
    Citation: Malaria Journal 2022 21:338
  10. Accurate detection of asymptomatic malaria parasitaemia in children living in high transmission areas is important for malaria control and reduction programmes that employ screen-and-treat surveillance strateg...

    Authors: Lindsey B. Turnbull, George Ayodo, Veronicah Knight, Chandy C. John, Megan S. McHenry and Tuan M. Tran
    Citation: Malaria Journal 2022 21:337
  11. Eotaxin-1 concentrations in plasma have been inversely associated with malaria exposure, malaria infection and pregnancy, but the effect of these conditions on the levels of the related chemokines eotaxin-2 an...

    Authors: Cristina Mancebo-Pérez, Marta Vidal, Ruth Aguilar, Diana Barrios, Azucena Bardají, Maria Ome-Kaius, Clara Menéndez, Stephen J. Rogerson, Carlota Dobaño, Gemma Moncunill and Pilar Requena
    Citation: Malaria Journal 2022 21:336
  12. Malaria remains a serious health problem in the southern border provinces of Thailand. The issue areas can be identified using an appropriate statistical model. This study aimed to investigate malaria for its ...

    Authors: Lumpoo Ammatawiyanon, Phattrawan Tongkumchum, Apiradee Lim and Don McNeil
    Citation: Malaria Journal 2022 21:334
  13. To understand how Plasmodium falciparum malaria is controlled, it is essential to elucidate the transcriptomic responses of the human host in naturally-exposed populations. Various individual studies of the human...

    Authors: Yan-hui Zhang, Xin-zhuan Su, Jian Li, Jia-jian Shi and Li-hua Xie
    Citation: Malaria Journal 2022 21:333
  14. Despite several efforts at addressing the barriers to adherence to the WHO-supported test, treat and track (T3) malaria case management guideline in Ghana, adherence remains a challenge. This study explored th...

    Authors: Augusta Soninour Kolekang, Yaw Afrane, Stephen Apanga, Dejan Zurovac, Anthony Kwarteng, Samuel Afari-Asiedu, Kwaku Poku Asante and Anthony Danso-Appiah
    Citation: Malaria Journal 2022 21:332
  15. Gametocytes are the sexual stages ensuring continuity of the development cycle of the parasite, as well as its transmission to humans. The efficacy of artemisinin-based anti-malarials against asexual stages of Pl...

    Authors: Malalanandrianina A. Rakotoarisoa, Jocia Fenomanana, Bronislaw Tchesterico Dodoson, Voahangy Hanitriniaina I. Andrianaranjaka and Arsène Ratsimbasoa
    Citation: Malaria Journal 2022 21:331
  16. In 2017, several new housing districts were constructed on Bioko Island, Equatorial Guinea. This case study assessed the impact construction projects had on mosquito larval habitats and the effectiveness of la...

    Authors: Guillermo A. García, Godwin Fuseini, Olivier Tresor Donfack, Rachel N. Wofford, Jose Antonio Mba Nlang, Prudencio Bibang Efiri, Valeriano Oluy Nsue Maye, Thomas A. Weppelmann, David Galick, Wonder Philip Phiri, Kylie DeBoer, Jordan M. Smith, Jeremias Nzamio Mba Eyono, Matilde Riloha Rivas, Carlos A. Guerra and Michael E. von Fricken
    Citation: Malaria Journal 2022 21:328
  17. Kalimantan is a part of Indonesia, which occupies the southern three-quarters of the island of Borneo, sharing a border with the Malaysian states of Sabah and Sarawak. Although most areas of Kalimantan have lo...

    Authors: Sri Riyati Sugiarto, J. Kevin Baird, Balbir Singh, Iqbal Elyazar and Timothy M. E. Davis
    Citation: Malaria Journal 2022 21:327
  18. Asymptomatic carriage of malaria parasites is common in high transmission intensity areas and confounds clinical case definitions for research studies. This is important for investigations that aim to identify...

    Authors: Kennedy Mwai, Irene Nkumama, Amos Thairu, James Mburu, Dennis Odera, Rinter Kimathi, Lydia Nyamako, James Tuju, Samson Kinyanjui, Eustasius Musenge and Faith Osier
    Citation: Malaria Journal 2022 21:326
  19. Seasonal patterns of malaria cases in many parts of Africa are generally associated with rainfall, yet in the dry seasons, malaria transmission declines but does not always cease. It is important to understand...

    Authors: Carolina Duque, Mukuma Lubinda, Japhet Matoba, Caison Sing’anga, Jennifer Stevenson, Timothy Shields and Clive J. Shiff
    Citation: Malaria Journal 2022 21:325
  20. Broflanilide is a newly discovered insecticide with a novel mode of action targeting insect γ-aminobutyric acid receptors. The efficacy of VECTRON T500, a wettable powder formulation of broflanilide, was assesse...

    Authors: Renaud Govoetchan, Augustin Fongnikin, Thomas Syme, Graham Small, Martial Gbegbo, Damien Todjinou, Mark Rowland, Derric Nimmo, Germain Gil Padonou and Corine Ngufor
    Citation: Malaria Journal 2022 21:324
  21. Human mobility behaviour modelling plays an essential role in the understanding and control of the spread of contagious diseases by limiting the contact among individuals, predicting the spatio-temporal evolut...

    Authors: Werissaw Haileselassie, Ashagrie Getnet, Hiwot Solomon, Wakgari Deressa, Guiyun Yan and Daniel M. Parker
    Citation: Malaria Journal 2022 21:323
  22. For children below 6 years with suspected severe malaria attending a health care provider unable to provide parenteral malaria treatment, pre-referral rectal artesunate (RAS) is recommended by the World Health...

    Authors: Phyllis Awor, Joseph Kimera, Proscovia Athieno, Gloria Tumukunde, Jean Okitawutshu, Antoinette Tshefu, Elizabeth Omoluabi, Aita Signorell, Nina Brunner, Jean-Claude Kalenga, Babatunde Akano, Kazeem Ayodeji, Charles Okon, Ocheche Yusuf, Giulia Delvento, Tristan Lee…
    Citation: Malaria Journal 2022 21:322
  23. Tanzania has made remarkable progress in reducing malaria burden and aims to transition from malaria control to sub-national elimination. In 2013, electronic weekly and monthly reporting platforms using the Di...

    Authors: Joseph J. Joseph, Humphrey R. Mkali, Erik J. Reaves, Osia S. Mwaipape, Ally Mohamed, Samwel N. Lazaro, Sijenunu Aaron, Frank Chacky, Anna Mahendeka, Hermes S. Rulagirwa, Mwendwa Mwenesi, Elibariki Mwakapeje, Ally Y. Ally, Chonge Kitojo, Naomi Serbantez, Ssanyu Nyinondi…
    Citation: Malaria Journal 2022 21:321
  24. The entire population of Mozambique is at risk for malaria, which remains one of the leading causes of death. The 2017–2022 National Malaria Strategic Plan focuses on reducing malaria morbidity and mortality i...

    Authors: Anton L. V. Avanceña, Angie Miller, Neide Canana, Janeth Dula, Abuchahama Saifodine, Baltazar Cadrinho and Elisa M. Maffioli
    Citation: Malaria Journal 2022 21:320
  25. Detection of malaria parasitaemia in samples that are negative by rapid diagnostic tests (RDTs) requires resource-intensive molecular tools. While pooled testing using a two-step strategy provides a cost-savin...

    Authors: Monica P. Shah, Winnie Chebore, Robert H. Lyles, Kephas Otieno, Zhiyong Zhou, Mateusz Plucinski, Lance A. Waller, Wycliffe Odongo, Kim A. Lindblade, Simon Kariuki, Aaron M. Samuels, Meghna Desai, Rebecca M. Mitchell and Ya Ping Shi
    Citation: Malaria Journal 2022 21:319
  26. Insecticidal mosquito-proof netting screens could combine the best features of insecticide-treated nets (ITNs) and indoor residual spraying (IRS), the two most important front line vector control interventions...

    Authors: Rogath Msoffe, Matilda Hewitt, John P. Masalu, Marcelina Finda, Deogratius R. Kavishe, Fredros O. Okumu, Emmanuel A. Mpolya, Emmanuel W. Kaindoa and Gerry F. Killeen
    Citation: Malaria Journal 2022 21:318
  27. Prompt diagnosis and treatment of malaria prevents a mild case from developing into severe disease and death. Unfortunately, parasitological testing of febrile children is greater in the public and formal priv...

    Authors: Olajoju Temidayo Soniran, Benedicta Ayiedu Mensah, Ndong Ignatius Cheng, Benjamin Abuaku and Collins Stephen Ahorlu
    Citation: Malaria Journal 2022 21:317
  28. Indonesia is progressing towards malaria elimination. To achieve this goal, intervention measures must be addressed to cover all Plasmodium species. Comprehensive control measures and surveillance programmes must...

    Authors: Irbah Rea Alvieda Nainggolan, Rycha Dwi Syafutri, Monica Nadya Sinambela, Clara Devina, Handayani, Beby Syofiani Hasibuan, Sriwipa Chuangchaiya, Paul C. S. Divis, Zulkarnain Md Idris, Ranti Permatasari and Inke Nadia Diniyanti Lubis
    Citation: Malaria Journal 2022 21:316
  29. Evaluating malaria control strategies for pregnant women is essential. The objective of this study was to determine the factors influencing antenatal care (ANC) visit attendance, complete intermittent preventi...

    Authors: Jean Claude Biteghe-Bi-Essone, Roméo Karl Imboumy-Limoukou, Jean Jordan Ekogha-Ovono, Sydney Maghendji-Nzondo, Pater Noster Sir-Ondo-Enguier, Lydie Sandrine Oyegue and Jean Bernard Lekana-Douki
    Citation: Malaria Journal 2022 21:315
  30. The global burden of malaria continues to be a significant public health concern. Despite advances made in therapeutics for malaria, there continues to be high morbidity and mortality associated with this infe...

    Authors: Esther Sarpong, Desmond Omane Acheampong, George Nkansah Rost Fordjour, Akwasi Anyanful, Enoch Aninagyei, Derek A. Tuoyire, Dee Blackhurst, George Boateng Kyei, Martins Ekor and Nicholas Ekow Thomford
    Citation: Malaria Journal 2022 21:314
  31. Malaria is one of the leading causes of morbidity and mortality among children under 5 years of age in Uganda. Although Karamoja sub-region has the highest prevalence of malaria, and one of the highest case fa...

    Authors: Jane Frances Zalwango, Joaniter I. Nankabirwa, Freddy Eric Kitutu, Rebecca Akunzirwe, Remmy Buhuguru, Joan Bayowa Rokani, Emmanuel Ssendikwanawa, Sarah Kiguli, Emmanuel Arinaitwe and Joan N. Kalyango
    Citation: Malaria Journal 2022 21:312
  32. A vital aspect of disease management and policy making lies in the understanding of the universal distribution of diseases. Nevertheless, due to differences all-over host groups and space–time outbreak activit...

    Authors: Jecinta U. Ibeji, Henry Mwambi and Abdul-Karim Iddrisu
    Citation: Malaria Journal 2022 21:311
  33. Recent research has established that acute kidney injury (AKI) is a common problem in severe paediatric malaria. Limited access to kidney diagnostic studies in the low resources settings where malaria is commo...

    Authors: Derby Tembo, Suzanna Mwanza, Chisambo Mwaba, Ifunanya Dallah, Somwe wa Somwe, Karl B. Seydel and Gretchen L. Birbeck
    Citation: Malaria Journal 2022 21:310
  34. Despite its effectiveness, the optimal use of the combination of insecticide-treated nets (ITN) and intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) remains low in ma...

    Authors: Ibrahima Barry, Almamy Amara Toure, Oumar Sangho, Abdoul Habib Beavogui, Diao Cisse, Abdourahamane Diallo, Aboubacar Sidiki Magassouba, Younoussa Sylla, Lancina Doumbia, Mahamoud Sama Cherif, Alseny Yarie Camara, Fatou Diawara, Moctar Tounkara, Alexandre Delamou and Seydou Doumbia
    Citation: Malaria Journal 2022 21:309
  35. Interleukin (IL)-1β is a proinflammatory cytokine that has a role in disease-related inflammation, including malaria. However, reports on the effect of IL-1β on malaria severity are inconsistent. Therefore, me...

    Authors: Aongart Mahittikorn, Pattamaporn Kwankaew, Pongruj Rattaprasert, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay and Manas Kotepui
    Citation: Malaria Journal 2022 21:308
  36. Malaria continues to be a leading cause of morbidity and mortality in Africa and conventional malaria control strategies, such as indoor residual spraying and insecticide-treated bed nets, have limited effecti...

    Authors: Takalani I. Makhanthisa, Leo Braack, Maria S. Bornman and Heike Lutermann
    Citation: Malaria Journal 2022 21:307
  37. Resistance to anti-malarial drugs is associated with polymorphisms in target genes and surveillance for these molecular markers is important to detect the emergence of mutations associated with drug resistance...

    Authors: Angela Patricia Guerra, Mario Javier Olivera, Liliana Jazmín Cortés, Stella M. Chenet, Alexandre Macedo de Oliveira and Naomi W. Lucchi
    Citation: Malaria Journal 2022 21:306
  38. Impacts of nationally directed malaria control interventions hinge on understanding malaria transmission and prevention at the community level. The decision to seek care or health-seeking behaviours provide va...

    Authors: Dominique E. Earland, Albino Francisco Bibe, Anísio Novela, João Ferrão and Kelly M. Searle
    Citation: Malaria Journal 2022 21:305
  39. The alertness and practice of health care providers (HCPs) in the correct management of suspected malaria (CMSM) (vigilance) is a central component of malaria surveillance following elimination, and it must be...

    Authors: Hosein Azizi, Reza Majdzadeh, Ayat Ahmadi, Ahmad Raeisi, Maryam Nazemipour, Mohammad Ali Mansournia and Allan Schapira
    Citation: Malaria Journal 2022 21:304
  40. Malaria in pregnancy control interventions have been implemented through antenatal care services for more than 2 decades in Ghana. The uptake of these interventions has seen steady improvement over the years. ...

    Authors: Gifty Dufie Ampofo, Joseph Osarfo, Matilda Aberese-Ako, Livingstone Asem, Mildred Naa Komey, Wahjib Mohammed, Anthony Adofo Ofosu and Harry Tagbor
    Citation: Malaria Journal 2022 21:303
  41. The resistance of Plasmodium falciparum to artemisinin-based (ART) drugs, the front-line drug family used in artemisinin-based combination therapy (ACT) for treatment of malaria, is of great concern. Mutations in...

    Authors: Tanyaluck Kampoun, Somdet Srichairatanakool, Parichat Prommana, Philip J. Shaw, Judith L. Green, Ellen Knuepfer, Anthony A. Holder and Chairat Uthaipibull
    Citation: Malaria Journal 2022 21:302
  42. School-based health (SBH) programmes that are contingent on primary school teachers are options to increase access to malaria treatment among learners. However, perceptions that provision of healthcare by teac...

    Authors: Jobiba Chinkhumba, Victor Kadzinje, Gomezgani Jenda, Michael Kayange and Don P. Mathanga
    Citation: Malaria Journal 2022 21:301
  43. Mathematical models provide an understanding of the dynamics of a Plasmodium falciparum blood-stage infection (within-host models), and can predict the impact of control strategies that affect the blood-stage of ...

    Authors: Thiery Masserey, Melissa A. Penny and Tamsin E. Lee
    Citation: Malaria Journal 2022 21:300
  44. The recent worldwide increase in malaria cases highlights the need for renewed efforts to eliminate malaria. The World Health Organization advocates that malaria surveillance becomes a core intervention. Curre...

    Authors: Michael Kayange, Bridon M’baya, Talent Hwandih, Jarob Saker, Thérèsa L. Coetzer and Marion Münster
    Citation: Malaria Journal 2022 21:299
  45. Urban malaria has received insufficient attention in the literature. The prevalence and clinical characteristics of Plasmodium falciparum infection amongst patients presenting with suspected malaria were investig...

    Authors: Daniel Z. Hodson, Yannick Mbarga Etoundi, Narcisse Mbatou Nghokeng, Raïhana Mohamadou Poulibe, Sonia Magne Djoko, Justin Goodwin, Glwadys Cheteug Nguesta, Tatiana Nganso, Jillian N. Armstrong, John J. Andrews, Elizabeth Zhang, Martina Wade, Carole Else Eboumbou Moukoko, Yap Boum II and Sunil Parikh
    Citation: Malaria Journal 2022 21:298
  46. The control of malaria, pneumonia, and diarrhoea is important for the reduction in morbidity and mortality among children under 5 years. Uganda has adopted the Integrated Community Case Management strategy usi...

    Authors: Fred Bagenda, Andrew Christopher Wesuta, Geren Stone, Moses Ntaro, Palka Patel, Jessica Kenney, Stephen Baguma, David Santson Ayebare, Shem Bwambale, Michael Matte, Peter Chris Kawungezi and Edgar Mugema Mulogo
    Citation: Malaria Journal 2022 21:296

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