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  1. The WHO cone test is one of three tests currently used to evaluate the efficacy of insecticide-treated bed nets (ITNs). It generates two test outputs, knockdown and 24-h mortality, both indicative of immediate...

    Authors: Angela Hughes, Agnes Matope, Mischa Emery, Keith Steen, Gregory Murray, Hilary Ranson, Philip J. McCall and Geraldine M. Foster
    Citation: Malaria Journal 2022 21:208
  2. Independent emergence and spread of artemisinin-resistant Plasmodium falciparum malaria have recently been confirmed in Africa, with molecular markers associated with artemisinin resistance increasingly detected....

    Authors: Frank M. Kagoro, Elizabeth Allen, Aaron Mabuza, Lesley Workman, Ray Magagula, Gerdalize Kok, Craig Davies, Gillian Malatje, Philippe J. Guérin, Mehul Dhorda, Richard J. Maude, Jaishree Raman and Karen I. Barnes
    Citation: Malaria Journal 2022 21:207
  3. Rapid emergence of Plasmodium resistance to anti-malarial drug mainstays has driven a continual effort to discover novel drugs that target different biochemical pathway (s) during infection. Plasma membrane Calci...

    Authors: Puji B. S. Asih, Josephine E. Siregar, Farahana K. Dewayanti, Normalita E. Pravitasari, Ismail E. Rozi, Andita F. M. Rizki, Rifqi Risandi, Kevin N. Couper, Delvac Oceandy and Din Syafruddin
    Citation: Malaria Journal 2022 21:206
  4. Malaria chemoprophylaxis using chloroquine (CQ) and primaquine (PQ) has been administered to resident soldiers in the 3rd Army of Republic of Korea (ROK) to prevent malaria infection since the year 1997. Due t...

    Authors: Jin-Jong Bong, Wonsig Lee, Chan Hee Lee, Quehn Park and Kyung Tae Noh
    Citation: Malaria Journal 2022 21:205
  5. Malaria is an infectious disease considered as one of the biggest causes of mortality in endemic areas. This life-threatening disease needs to be quickly diagnosed and treated. The standard diagnostic tools re...

    Authors: Azza Bouzayene, Rizwana Zaffaroullah, Justine Bailly, Liliane Ciceron, Véronique Sarrasin, Sandrine Cojean, Nicolas Argy, Sandrine Houzé and Valentin Joste
    Citation: Malaria Journal 2022 21:204
  6. An estimated 1.5 billion malaria cases and 7.6 million malaria deaths have been averted globally since 2000; long-lasting insecticidal nets (LLINs) have contributed an estimated 68% of this reduction. Insuffic...

    Authors: Lucy Paintain, Richard Kpabitey, Felix Nyanor-Fosu, Danielle Piccinini Black, Kathryn Bertram, Jayne Webster, Catherine Goodman and Matt Lynch
    Citation: Malaria Journal 2022 21:203
  7. In Burkina Faso, malaria remains the first cause of medical consultation and hospitalization in health centres. First-line case management of malaria in the country’s health facilities is based on the use of a...

    Authors: Denise Hien, Jean Moise Tanga Kaboré, Mohamadou Siribié, Issiaka Soulama, Nouhoun Barry, Adama Baguiya, Alfred Bewendtaoré Tiono, André-Marie Tchouatieu and Sodiomon Bienvenu Sirima
    Citation: Malaria Journal 2022 21:202
  8. Rapid diagnostic tests (RDTs) detecting Plasmodium falciparum histidine-rich protein 2 (HRP2) have been an important tool for malaria diagnosis, especially in resource-limited settings lacking quality microscopy....

    Authors: Khalid B. Beshir, Jonathan B. Parr, Jane Cunningham, Qin Cheng and Eric Rogier
    Citation: Malaria Journal 2022 21:201

    The Correction to this article has been published in Malaria Journal 2022 21:266

  9. India has made considerable progress in malaria reduction over the past two decades, with government-sponsored indoor residual spraying (IRS) and insecticide-treated bed net (ITN) or long-lasting insecticidal ...

    Authors: Mattimi Passah, Carinthia Balabet Nengnong, Mark L. Wilson, Jane M. Carlton, Larry Kharbamon and Sandra Albert
    Citation: Malaria Journal 2022 21:200
  10. Coronavirus disease 2019 (COVID-19) often causes atypical clinical manifestations similar to other infectious diseases. In malaria-endemic areas, the pandemic situation will very likely result in co-infection ...

    Authors: Tri Pudy Asmarawati, Okla Sekar Martani, Bramantono Bramantono and Muhammad Vitanata Arfijanto
    Citation: Malaria Journal 2022 21:199
  11. Important knowledge gaps exist in the understanding of the management of the risks of imported malaria in Canada among Francophone immigrants from sub-Saharan Africa (FISSA). The aim of this cross-sectional st...

    Authors: Taylor A. Hanna, Ali Ahmed, Rémi Vincent, Kongnon Sangué Coulibaly, Youssef Ahmed, Ryland Petrick, Etienne Vincent, Mélanie El Hafid, Michel T. Hawkes, Srilata Ravi and Sedami Gnidehou
    Citation: Malaria Journal 2022 21:197
  12. Cerebral malaria (CM) results in significant paediatric death and neurodisability in sub-Saharan Africa. Several different alterations to typical Transcranial Doppler Ultrasound (TCD) flow velocities and wavef...

    Authors: Nicole F. O’Brien, Yudy Fonseca, Hunter C. Johnson, Douglas Postels, Gretchen L. Birbeck, Yamikani Chimalizeni, Karl B. Seydel, Montfort Bernard Gushu, Tusekile Phiri, Sylvester June, Karen Chetcuti, Lorenna Vidal, Manu S. Goyal and Terrie E. Taylor
    Citation: Malaria Journal 2022 21:196
  13. Malaria in pregnancy doubles the risk of low birthweight; up to 11% of all neonatal deaths in sub-Saharan Africa are associated with malaria in pregnancy. To prevent these and other adverse health consequences...

    Authors: Beth L. Rubenstein, Jobiba Chinkhumba, Ethel Chilima, Collins Kwizombe, Ashley Malpass, Shelby Cash, Katherine Wright, Peter Troell, Humphrey Nsona, Fannie Kachale, Doreen Ali, Evans Kaunda, Sosten Lankhulani, Michael Kayange, Don P. Mathanga, John Munthali…
    Citation: Malaria Journal 2022 21:195
  14. In Senegal, malaria morbidity has sharply decreased over these past years. However, malaria epidemiology remains heterogeneous with persistent transmission in the southeastern part of the country and many case...

    Authors: Fassiatou Tairou, Abdoulaye Diallo, Ousmane Sy, Aminatou Kone, Isaac Akhenaton Manga, Khadim Sylla, Souleye Lelo, Cheikh Binetou Fall, Doudou Sow, Magatte Ndiaye, Babacar Faye and Roger C. K. Tine
    Citation: Malaria Journal 2022 21:193
  15. High levels of genetic diversity are common characteristics of Plasmodium falciparum parasite populations in high malaria transmission regions. There has been a decline in malaria transmission intensity over 12 y...

    Authors: Kelvin M. Kimenyi, Kevin Wamae, Joyce M. Ngoi, Zaydah R. de Laurent, Leonard Ndwiga, Victor Osoti, George Obiero, Abdirahman I. Abdi, Philip Bejon and Lynette Isabella Ochola-Oyier
    Citation: Malaria Journal 2022 21:192
  16. Antibody and cellular memory responses following vaccination are important measures of immunogenicity. These immune markers were quantified in the framework of a vaccine trial investigating the malaria vaccine...

    Authors: Odilon Nouatin, Javier Ibáñez, Rolf Fendel, Ulysse A. Ngoa, Freia-Raphaella Lorenz, Jean-Claude Dejon-Agobé, Jean Ronald Edoa, Judith Flügge, Sina Brückner, Meral Esen, Michael Theisen, Stephen L. Hoffman, Kabirou Moutairou, Adrian J. F. Luty, Bertrand Lell, Peter G. Kremsner…
    Citation: Malaria Journal 2022 21:191
  17. To avoid misuse of anti-malarials, correct diagnosis of fever prior to drug prescription is essential. Presumptive treatment in the private healthcare sector is a concern in Nigeria, where availability of affo...

    Authors: Hannah M. Edwards, Rubaiyath Sarwar, Parvez Mahmud, Shekarau Emmanuel, Kolawole Maxwell and James K. Tibenderana
    Citation: Malaria Journal 2022 21:190
  18. Malaria is a significant parasitic infection, and human infection is mediated by mosquito (Anopheles) biting and subsequent transmission of protozoa (Plasmodium) to the blood. Carbonic anhydrases (CAs) are known ...

    Authors: Reza Zolfaghari Emameh, Harlan R. Barker, Hannu Turpeinen, Seppo Parkkila and Vesa P. Hytönen
    Citation: Malaria Journal 2022 21:189
  19. A study was conducted prior to implementing a cluster-randomized controlled trial (CRT) of a lethal house lure strategy in central Côte d’Ivoire to provide baseline information on malaria indicators in 40 vill...

    Authors: Rosine Z. Wolie, Alphonsine A. Koffi, Leslie Ayuk-Taylor, Ludovic P. Ahoua Alou, Eleanore D. Sternberg, Oulo N’Nan-Alla, Yao N’Guessan, Amal Dahounto, Welbeck A. Oumbouke, Innocent Z. Tia, Simon-Pierre A. N’Guetta, Jackie Cook, Matthew B. Thomas and Raphael N’Guessan
    Citation: Malaria Journal 2022 21:188
  20. The World Health Organization (WHO) recommends surveillance of molecular markers of resistance to anti-malarial drugs. This is particularly important in the case of mass drug administration (MDA), which is end...

    Authors: Sophie Moss, Emilia Mańko, Sanjeev Krishna, Susana Campino, Taane G. Clark and Anna Last
    Citation: Malaria Journal 2022 21:186
  21. Malaria is a major cause of morbidity and mortality globally, especially in sub-Saharan Africa. Widespread resistance to pyrethroids threatens the gains achieved by vector control. To counter resistance to pyr...

    Authors: Joshua Yukich, Peder Digre, Sara Scates, Luc Boydens, Emmanuel Obi, Nicky Moran, Allison Belemvire, Mariandrea Chamorro, Benjamin Johns, Keziah L. Malm, Lena Kolyada, Ignatius Williams, Samuel Asiedu, Seydou Fomba, Jules Mihigo, Desire Boko…
    Citation: Malaria Journal 2022 21:185
  22. In Ethiopia, thousands of seasonal migrant workers travel from non-malaria or mild malaria transmission areas to malaria-endemic areas for seasonal farm activities. Most of these migrants stay in the farm area...

    Authors: Tesfaye Tilaye, Belay Tessema and Kassahun Alemu
    Citation: Malaria Journal 2022 21:184
  23. To sustain high universal Long-Lasting Insecticidal Nets (LLINs) coverage, affordable nets that provide equivalent or better protection than standard LLINs, are required. Test facilities evaluating new LLINs r...

    Authors: Salum Azizi, Janneke Snetselaar, Robert Kaaya, Johnson Matowo, Hudson Onen, Magreth Shayo, Ezekia Kisengwa, Evod Tilya, Baltazari Manunda, Benson Mawa, Franklin Mosha and Matthew Kirby
    Citation: Malaria Journal 2022 21:183
  24. Usage of mosquito bed nets and the practice of other prevention methods are essential for the prevention of malaria in endemic areas. Proper community knowledge about malaria and prompt treatment-seeking behav...

    Authors: Elfatih A. Hasabo, Rawan I. Khalid, Ghassan E. Mustafa, Ruaa E. Taha, Riham S. Abdalla, Reham A. Mohammed, Mazin S. Haroun, Rawaa Adil, Riham A. Khalil, Rawaa M. Mansour, Reham K. Mohamed and Heitham Awadalla
    Citation: Malaria Journal 2022 21:182
  25. Vector mosquito biting intensity is an important measure to understand malaria transmission. Human landing catch (HLC) is an effective but labour-intensive, expensive, and potentially hazardous entomological s...

    Authors: Isaac Haggai Namango, Carly Marshall, Adam Saddler, Amanda Ross, David Kaftan, Frank Tenywa, Noely Makungwa, Olukayode G. Odufuwa, Godfrey Ligema, Hassan Ngonyani, Isaya Matanila, Jameel Bharmal, Jason Moore, Sarah J. Moore and Manuel W. Hetzel
    Citation: Malaria Journal 2022 21:181
  26. Nutrient acquisition and allocation integrate foraging and life-history traits in insects. To compensate for the lack of a particular nutrient at different life stages, insects may acquire these through supple...

    Authors: Mengistu Dawit, Sharon R. Hill, Göran Birgersson, Habte Tekie and Rickard Ignell
    Citation: Malaria Journal 2022 21:180
  27. Water pollution due to uncontrolled release of chemical pollutants is an important global problem. Its effect on medically important insects, especially mosquitoes, is a critical issue in the epidemiology of m...

    Authors: Mahmoud Fazeli-Dinan, Mostafa Azarnoosh, Mehmet Salih Özgökçe, Hsin Chi, Nasibeh Hosseini-Vasoukolaei, Farzad Motevalli Haghi, Mohamad Ali Zazouli, Seyed Hassan Nikookar, Reza Dehbandi, Ahmadali Enayati, Morteza Zaim and Janet Hemingway
    Citation: Malaria Journal 2022 21:178
  28. Immunoassay platforms that simultaneously detect malaria antigens including histidine-rich protein 2 (HRP2)/HRP3 and Plasmodium lactate dehydrogenase (pLDH), are useful epidemiological tools for rapid diagnostic ...

    Authors: Ihn Kyung Jang, Alfons Jiménez, Andrew Rashid, Rebecca Barney, Allison Golden, Xavier C. Ding, Gonzalo J. Domingo and Alfredo Mayor
    Citation: Malaria Journal 2022 21:176
  29. The collection and utilization of surveillance data is essential in monitoring progress towards achieving malaria elimination, in the timely response to increases in malaria case numbers and in the assessment ...

    Authors: Jade D. Rae, Suphak Nosten, Ladda Kajeechiwa, Jacher Wiladphaingern, Daniel M. Parker, Jordi Landier, Aung Myint Thu, Hsa Dah, Aye Be, Win Cho Cho, K.’Nyaw Paw, Eh Shee Paw, Paw Bway Shee, Christ Poe, Chit Nu, Baw Nyaw…
    Citation: Malaria Journal 2022 21:175
  30. The prevalence and death rate arising from malaria infection, and emergence of other diseases showing similar symptoms to malaria require the development of malaria-specific and sensitive devices for its diagn...

    Authors: Adewoyin Martin Ogunmolasuyi, Ronen Fogel, Heinrich Hoppe, Dean Goldring and Janice Limson
    Citation: Malaria Journal 2022 21:174
  31. Copper is an essential metal for living organisms as a catalytic co-factor for important enzymes, like cytochrome c oxidase the final enzyme in the electron transport chain. Plasmodium falciparum parasites in inf...

    Authors: Abdulmalik Abdullahi Salman and J. P. Dean Goldring
    Citation: Malaria Journal 2022 21:173
  32. Low-level of malaria transmission persist in Zanzibar despite high coverage of core vector control interventions. This study was carried out in hot-spot sites to better understand entomological factors that ma...

    Authors: Revocatus M. Musiba, Brian B. Tarimo, April Monroe, Dickson Msaky, Halfan Ngowo, Kimberly Mihayo, Alex Limwagu, Godlove T. Chilla, Gasper K. Shubis, Ahmada Ibrahim, George Greer, Juma H. Mcha, Khamis A. Haji, Faiza B. Abbas, Abdullah Ali, Fredros O. Okumu…
    Citation: Malaria Journal 2022 21:172
  33. Subclinical infection with Plasmodium falciparum remains highly prevalent, yet diagnosing these often low-density infections remains a challenge. Infections can be subpatent, falling below the limit of detection ...

    Authors: Jason P. Mooney, Sophia M. DonVito, Maimuna Jahateh, Haddy Bittaye, Christian Bottomley, Umberto D’Alessandro and Eleanor M. Riley
    Citation: Malaria Journal 2022 21:171
  34. Despite the introduction of efficacious interventions for malaria control, sub-Saharan Africa continues to bear the highest burden of malaria and its associated effects on vulnerable populations, such as pregn...

    Authors: Matilda Aberese-Ako, Phidelia Doegah, Evelyn Acquah, Pascal Magnussen, Evelyn Ansah, Gifty Ampofo, Dominic Dankwah Agyei, Desmond Klu, Elsie Mottey, Julie Balen, Safiatou Doumbo, Wilfred Mbacham, Ouma Gaye, Margaret Gyapong, Seth Owusu-Agyei and Harry Tagbor
    Citation: Malaria Journal 2022 21:170
  35. The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine ...

    Authors: Warunee Hanpithakpong, Nicholas P. J. Day, Nicholas J. White and Joel Tarning
    Citation: Malaria Journal 2022 21:169
  36. Malaria remains a major cause of morbidity and death among children less than 5 years of age. In Togo, despite intensification of malaria control interventions, malaria remained highly prevalent, with signific...

    Authors: Gountante Kombate, Wakpaouyare Gmakouba, Susana Scott, Komi Ameko Azianu, Didier Koumavi Ekouevi and Marianne A. B. van der Sande
    Citation: Malaria Journal 2022 21:168
  37. Malaria is a major cause of morbidity and mortality worldwide. According to the World Health Organization 2021 malaria report, it is considered to be endemic in 85 countries and territories. Malaria eliminatio...

    Authors: Abtie Abebaw, Yibeltal Aschale, Tadesse Kebede and Asrat Hailu
    Citation: Malaria Journal 2022 21:167
  38. The East Nusa Tenggara province, Indonesia, contributed to 5% of malaria cases nationally in 2020, with other mosquito-borne diseases, such as dengue and filariasis also being endemic. Monitoring of spatial an...

    Authors: Dendi H. Permana, Siti Zubaidah, Lepa Syahrani, Puji B. S. Asih, Din Syafruddin, Ismail E. Rozi, Anggi P. N. Hidayati, Sully Kosasih, Farahana K. Dewayanti, Nia Rachmawati, Rifqi Risandi, Michael J. Bangs, Claus Bøgh, Jenna R. Davidson, Allison L. Hendershot, Timothy A. Burton…
    Citation: Malaria Journal 2022 21:166
  39. The Community-Based Malaria Management (CBMM) strategy, introduced in 2013 and expanded to all health facilities and health posts in Afghanistan by 2016, aimed to deliver rapid diagnostic testing and more time...

    Authors: Sayed Daoud Mahmoodi, Abdul Alim Atarud, Ahmad Walid Sediqi, Sarah Gallalee, Willi McFarland, Temesgen Birara Aynie, Mohmmad Sami Nahzat, Hamida Hamid, Ghulam Qader Qader, Mohammad Shoaib Tamim and Ali Mirzazadeh
    Citation: Malaria Journal 2022 21:165
  40. The World Health Organization World Malaria Report of 2019 indicated an estimated 228 million cases of malaria occurred worldwide in 2018. More than 75% of the total area of Ethiopia is malarious, making malar...

    Authors: Yamlak Gindola, Desalegn Getahun, David Sugerman, Eric Tongren, Ryan Tokarz, Mesfin Wossen, Kassahun Demissie, Etsehiwot Zemelak, Akuma Okugn, Jimmawork Wendimu, Girmay Hailu, Mesfin Tegistu and Dumesa Begna
    Citation: Malaria Journal 2022 21:164
  41. The colonization of mosquitoes susceptible to Plasmodium vivax via direct membrane feeding assay (DMFA) has the potential to significantly advance our knowledge of P. vivax biology, vector-parasite interaction an...

    Authors: Najara A. C. Santos, Alice O. Andrade, Thais C. Santos, Leandro N. Martinez, Amália S. Ferreira, Alessandra S. Bastos, Mirilene M. Martins, José D. C. Pontual, Carolina B. G. Teles, Jansen F. Medeiros and Maisa S. Araújo
    Citation: Malaria Journal 2022 21:163
  42. Migrant populations are at an increased risk of exposure to malaria due to their nature of work and seasonal migration. This study aimed to compare malaria prevention behaviours and care-seeking practices amon...

    Authors: Ye Kyaw Aung, Su Su Zin, Kemi Tesfazghi, Mahesh Paudel, May Me Thet and Si Thu Thein
    Citation: Malaria Journal 2022 21:162
  43. It is often assumed that the population dynamics of the malaria vector Anopheles funestus, its role in malaria transmission and the way it responds to interventions are similar to the more elaborately characteriz...

    Authors: Halfan S. Ngowo, Fredros O. Okumu, Emmanuel E. Hape, Issa H. Mshani, Heather M. Ferguson and Jason Matthiopoulos
    Citation: Malaria Journal 2022 21:161
  44. The development of resistance by Plasmodium falciparum to anti-malarial drugs impedes any benefits of the drug. In addition, absence or delayed availability of current anti-malarial drugs in remote areas has the ...

    Authors: Mary Aigbiremo Oboh, Fatou Faal, Oluwagbemisola Elizabeth Adeniji, Simon Correa, Anthony Uyimulam Amawu, Ekon Ogban, Eva Heinz, Grant Hughes, Martin M. Meremikwu and Alfred Amambua-Ngwa
    Citation: Malaria Journal 2022 21:160
  45. Malaria control relies heavily on the use of anti-malarial drugs and insecticides against malaria parasites and mosquito vectors. Drug and insecticide resistance threatens the effectiveness of conventional mal...

    Authors: Charles Mulamba, Chris Williams, Katharina Kreppel, Jean Bosco Ouedraogo and Ally I. Olotu
    Citation: Malaria Journal 2022 21:159

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