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  1. Since 2013, the National Malaria Control Programme in mainland Tanzania has deployed annual distributions of insecticide-treated nets (ITNs) through primary schools to maintain ITN access and use. This School ...

    Authors: Hannah Koenker, Matt Worges, Benjamin Kamala, Peter Gitanya, Frank Chacky, Samwel Lazaro, Charles Dismas Mwalimu, Sijenunu Aaron, Deodatus Mwingizi, David Dadi, Ato Selby, Naomi Serbantez, Lulu Msangi, Dana Loll and Joshua Yukich
    Citation: Malaria Journal 2022 21:246
  2. The goal of this study was to understand the epidemiological characteristics of imported malaria in Shanghai specifically during the epidemic period of novel corona-virus pneumonia (COVID-19), to provide a ref...

    Authors: Min Zhu, Chengang Zhang, Yaoguang Zhang, Zhenyu Wang, Xiaojiang Ma, Simin Dai and Jian Chen
    Citation: Malaria Journal 2022 21:245
  3. Parasites are recognized for their ability to modify host physiology and behaviours in ways that increase parasite fitness. Protozoan parasites of the genus Plasmodium are a group of widespread vector-borne paras...

    Authors: Dayvion R. Adams, Andrew J. Golnar, Jacob I. Meyers, Michel A. Slotman and Gabriel L. Hamer
    Citation: Malaria Journal 2022 21:244
  4. The search for pharmacologically effective agents among molecules bearing multiple functionalities is commonly practiced. In continuation of the search for new anti-malarial agents, new pyrazole-hydrazine coup...

    Authors: Akachukwu Ibezim, Martha N. Ofokansi, Xavier Ndukwe, Chidera S. Chiama, Bonaventure C. Obi, Ogechukwu N. Isiogugu, Peter E. Ikechukwu, Akachukwu M. Onwuka, Stella A. Ihim, Jonnie N. Asegbeloyin and Ngozi J. Nwodo
    Citation: Malaria Journal 2022 21:243
  5. Targeted research on residual malaria transmission is important to improve strategies in settings pursuing elimination, where transmission reductions prove challenging. This study aimed to detect and character...

    Authors: Jean Marius Rakotondramanga, Inès Vigan-Womas, Laura C. Steinhardt, Aina Harimanana, Elisabeth Ravaoarisoa, Tsikiniaina L. Rasoloharimanana, Seheno Razanatsiorimalala, Amy Wesolowski, Milijaona Randrianarivelojosia, Benjamin Roche and Andres Garchitorena
    Citation: Malaria Journal 2022 21:242
  6. As Indonesia aims for malaria elimination by 2030, provisional malaria epidemiology and risk factors evaluation are important in pursue of this national goal. Therefore, this study aimed to understand the risk...

    Authors: Fahmi Fahmi, Ayodhia Pitaloka Pasaribu, Minerva Theodora and Kinley Wangdi
    Citation: Malaria Journal 2022 21:241

    The Correction to this article has been published in Malaria Journal 2022 21:335

  7. Malaria infection during pregnancy can cause significant morbidity and mortality to a pregnant woman, her fetus and newborn. In areas of high endemic transmission, gravidity is an important risk factor for inf...

    Authors: Ayodele Akinnawo, Kaali Seyram, Ellen Boamah Kaali, Samuel Harrison, David Dosoo, Matthew Cairns and Kwaku Poku Asante
    Citation: Malaria Journal 2022 21:240
  8. Globally, nearly half of all deaths among children under the age of 5 years can be attributed to malaria, diarrhoea, and pneumonia. A significant proportion of these deaths occur in sub-Saharan Africa. Despite...

    Authors: Neha Batura, Frida Kasteng, Juliao Condoane, Benson Bagorogosa, Ana Cristina Castel-Branco, Edmound Kertho, Karin Källander, Seyi Soremekun, Raghu Lingam and Anna Vassall
    Citation: Malaria Journal 2022 21:239
  9. Pyrethroid resistance observed in populations of malaria vectors is widespread in Ethiopia and could potentially compromise the effectiveness of insecticide-based malaria vector control interventions. In this ...

    Authors: Delenasaw Yewhalaw, Meshesha Balkew, Endalew Zemene, Sheleme Chibsa, Peter Mumba, Cecilia Flatley, Aklilu Seyoum, Melissa Yoshimizu, Sarah Zohdy, Dereje Dengela and Seth Irish
    Citation: Malaria Journal 2022 21:238
  10. The vector species in the Amazon River Basin are regionally and locally diverse, which makes it imperative to understand and compare their roles in malaria transmission to help select appropriate methods of in...

    Authors: Robert H. Zimmerman, Allan K. R. Galardo, L Philip Lounibos, Clicia Galardo, A. Kadir Bahar and Edzard van Santen
    Citation: Malaria Journal 2022 21:237
  11. Malaria rapid diagnostic tests (RDTs) have expanded diagnostic service to remote endemic communities in Ethiopia, where 70% of malaria services per annum are reliant on them. However, diagnostic strategies are...

    Authors: Sindew Mekasha Feleke, Bokretsion Gidey, Hussein Mohammed, Desalegn Nega, Dereje Dillu, Mebrhatom Haile, Hiwot Solomon, Jonathan B. Parr, Getachew Tollera, Geremew Tasew, Hassen Mamo and Beyene Petros
    Citation: Malaria Journal 2022 21:236
  12. Evolutionary pressures lead to the selection of efficient malaria vectors either resistant or susceptible to Plasmodium parasites. These forces may favour the introduction of species genotypes that adapt to new b...

    Authors: Shirley A. Onyango, Kevin O. Ochwedo, Maxwell G. Machani, Julius O. Olumeh, Isaiah Debrah, Collince J. Omondi, Sidney O. Ogolla, Ming-Chieh Lee, Guofa Zhou, Elizabeth Kokwaro, James W. Kazura, Yaw A. Afrane, Andrew K. Githeko, Daibin Zhong and Guiyun Yan
    Citation: Malaria Journal 2022 21:235
  13. To contribute to the mission of the National Malaria Control Programme (NMCP) and guide future interventions in Cameroon in general, and in Makenene in particular, this study assessed the knowledge, attitudes ...

    Authors: Joel Djoufounna, Roland Bamou, Marie Paul Audrey Mayi, Nelly Armanda Kala-Chouakeu, Raymond Tabue, Parfait Awono-Ambene, Dorothy Achu-Fosah, Christophe Antonio-Nkondjio and Timoléon Tchuinkam
    Citation: Malaria Journal 2022 21:234
  14. Rapid diagnostic tests (RDTs) that rely on the detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) have become key tools for diagnosing P. falciparum infection. The utility of RDTs can be limited...

    Authors: Louise Marquart, Lachlan Webb, Peter O’Rourke, Michelle L. Gatton, Michelle S. Hsiang, Michael Kalnoky, Ihn Kyung Jang, Henry Ntuku, Davis R. Mumbengegwi, Gonzalo J. Domingo, James S. McCarthy and Sumudu Britton
    Citation: Malaria Journal 2022 21:233
  15. Data integration and visualisation techniques have been widely used in scientific research to allow the exploitation of large volumes of data and support highly complex or long-lasting research questions. Inte...

    Authors: Alberto Pietro Sironi, Juracy Bertoldo, Vanderson Sampaio, Danilo Coimbra, Davide Rasella and Marcos Ennes Barreto
    Citation: Malaria Journal 2022 21:232
  16. The increase in detections of Plasmodium vivax infection in Duffy-negative individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy Binding Protein-Duffy antigen receptor for chemokin...

    Authors: Andargie Abate, Isabelle Bouyssou, Solenne Mabilotte, Cecile Doderer-Lang, Laurent Dembele, Didier Menard and Lemu Golassa
    Citation: Malaria Journal 2022 21:230
  17. The automated haematology analyzer XN-31 prototype (XN-31p) is a new flow cytometry-based device developed to measure the number and the ratio of malaria-infected red blood cells (MI-RBC) with a complete blood...

    Authors: Kanako Komaki-Yasuda, Satoshi Kutsuna, Miki Kawaguchi, Mina Kamei, Kinya Uchihashi, Keiji Nakamura, Takato Nakamoto, Norio Ohmagari and Shigeyuki Kano
    Citation: Malaria Journal 2022 21:229
  18. The use of long-lasting insecticide-treated nets (LLINs) is one of the main malaria prevention method promoted by the World Health Organization (WHO) in Côte d'Ivoire. LLIN-coverage has reached 95% since 2015 ...

    Authors: Gnagoran Kouakou Daniel N’Guessan, Fangala Hamidou Coulibaly, Antoine Marc Gaby Barreaux, Roseline Josée Yapo, Kouassi Arsène Adou, Emmanuel Tia and Florence Fournet
    Citation: Malaria Journal 2022 21:228
  19. Rapid diagnostic tests (RDT) are widely used for malaria diagnosis in Madagascar, where Plasmodium falciparum is the predominant species. Molecular diagnosis is essential for malaria surveillance, but requires ad...

    Authors: Voahangy Hanitriniaina I. Andrianaranjaka, Elisabeth Ravaoarisoa, Tovonahary A. Rakotomanga, Fanomezantsoa Ralinoro, Danielle A. Doll Rakoto, Ranjàna H. Randrianarivo, Victor Jeannoda and Arsène Ratsimbasoa
    Citation: Malaria Journal 2022 21:227
  20. Gene drives are a genetic engineering method where a suite of genes is inherited at higher than Mendelian rates and has been proposed as a promising new vector control strategy to reinvigorate the fight agains...

    Authors: Shirley Leung, Nikolai Windbichler, Edward A Wenger, Caitlin A Bever and Prashanth Selvaraj
    Citation: Malaria Journal 2022 21:226
  21. Gene drive mosquitoes are increasingly considered a potential transformational tool for vector control of malaria mosquitoes. As part of efforts to promote responsible research in this field, a number of guida...

    Authors: Lea Pare Toe, Bakara Dicko, Richard Linga, Nourou Barry, Mouhamed Drabo, Naima Sykes and Delphine Thizy
    Citation: Malaria Journal 2022 21:225
  22. Despite the large-scale rollout of malaria rapid diagnostic tests (RDTs) in Tanzania, many healthcare providers (HCPs) continue using blood film microscopy (BFM) and clinical examination to diagnose malaria, w...

    Authors: Leah F. Bohle, Ally-Kebby Abdallah, Francesco Galli, Robert Canavan and Kate Molesworth
    Citation: Malaria Journal 2022 21:224
  23. Thailand’s strong malaria elimination programme relies on effective implementation of its 1-3-7 surveillance strategy, which was endorsed and implemented nationwide in 2016. For each confirmed malaria patient,...

    Authors: Prayuth Sudathip, Sathapana Naowarat, Suravadee Kitchakarn, Deyer Gopinath, Donal Bisanzio, Niparueradee Pinyajeerapat, David Sintasath and Jui A. Shah
    Citation: Malaria Journal 2022 21:222
  24. Many Plasmodium infections in endemic regions exist at densities below the limit of detection of standard diagnostic tools. These infections threaten control efforts and may impact vaccine and therapeutic drug st...

    Authors: Dianna E. B. Hergott, Tonny J. Owalla, Jennifer E. Balkus, Bernadette Apio, Jimmy Lema, Barbara Cemeri, Andrew Akileng, Annette M. Seilie, Chris Chavtur, Weston Staubus, Ming Chang, Thomas G. Egwang and Sean C. Murphy
    Citation: Malaria Journal 2022 21:221
  25. Malaria related mortality is associated with significant deregulation of host inflammatory factors such as interferon-inducible protein 10, a member of the CXC or α-subfamily (CXCL10), and host angiogenic fact...

    Authors: Cecilia Elorm Lekpor, Felix Botchway, Kwadwo Asamoah Kusi, Andrew A. Adjei, Michael D. Wilson, Jonathan K. Stiles and Nana O. Wilson
    Citation: Malaria Journal 2022 21:220
  26. More than 90% of malaria cases occur in Africa where the disease is transmitted by Anopheles gambiae and Anopheles arabiensis. This study evaluated the anti-mosquito properties of Juniperus virginiana (JVO) and P...

    Authors: Revocatus Yohana, Paulo S. Chisulumi, Winifrida Kidima, Azar Tahghighi, Naseh Maleki-Ravasan and Eliningaya J. Kweka
    Citation: Malaria Journal 2022 21:219
  27. Malaria remains endemic in Bangladesh, with the majority of cases occurring in forested, mountainous region in the Chittagong Hill Tracts (CHT). This area is home to Bengali and diverse groups of indigenous pe...

    Authors: Tiffany Huwe, Mohammad Golam Kibria, Fatema Tuj Johora, Ching Swe Phru, Nusrat Jahan, Mohammad Sharif Hossain, Wasif Ali Khan, Ric N. Price, Benedikt Ley, Mohammad Shafiul Alam and Cristian Koepfli
    Citation: Malaria Journal 2022 21:218
  28. Interleukin (IL)-4 had been linked to malaria severity, but the findings are controversial, and the evidence is inconsistent and imprecise. In the current investigation, data on IL-4 levels in patients with se...

    Authors: Kwuntida Uthaisar Kotepui, Phiman Thirarattanasunthon, Pongruj Rattaprasert and Manas Kotepui
    Citation: Malaria Journal 2022 21:217
  29. Plasmodium falciparum has been becoming resistant to the currently used anti-malarial drugs. Searching for new drug targets is urgently needed for anti-malarial development. DNA helicases separating double-strand...

    Authors: Pongruj Rattaprasert, Pattra Suntornthiticharoen, Paviga Limudomporn, Kanthinich Thima and Porntip Chavalitshewinkoon-Petmitr
    Citation: Malaria Journal 2022 21:216
  30. To eliminate malaria in southern Mozambique, the National Malaria Control Programme and its partners are scaling up indoor residual spraying (IRS) activities in two provinces, Gaza and Inhambane. An entomologi...

    Authors: Celso Alafo, Helena Martí-Soler, Mara Máquina, Arlindo Malheia, Ayesha S. Aswat, Lizette L. Koekemoer, James Colborn, Neil F. Lobo, Allison Tatarsky, Yasmin A. Williams, Dulcisária Marrenjo, Nelson Cuamba, Regina Rabinovich, Pedro Alonso, Pedro Aide, Francisco Saúte…
    Citation: Malaria Journal 2022 21:215
  31. Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is conducted by measuring physiochemical parameters, but not bioefficacy against malaria mosquitoes. This study ...

    Authors: Stephen G. Mbwambo, Nakei Bubun, Emmanuel Mbuba, Jason Moore, Kasiani Mbina, Dismas Kamande, Moses Laman, Emmanuel Mpolya, Olukayode G. Odufuwa, Tim Freeman, Stephan Karl and Sarah J. Moore
    Citation: Malaria Journal 2022 21:214
  32. Thailand’s National Malaria Elimination Strategy 2017–2026 seeks to increase domestic support and financing for malaria elimination. During 2018–2020, through a series of training sessions, public health offic...

    Authors: Prayuth Sudathip, Pratin Dharmarak, Sara Rossi, Nutthawoot Promda, Gretchen Newby, Erika Larson, Deyer Gopinath, Jerdsuda Kanjanasuwan, Praparat Promeiang, Cheewanan Lertpiriyasuwat, Darin Areechokchai and Preecha Prempree
    Citation: Malaria Journal 2022 21:213
  33. Prompt diagnosis and treatment of malaria contributes to reduced morbidity, particularly among children and pregnant women; however, in Madagascar, care-seeking for febrile illness is often delayed. To describ...

    Authors: Rachel Favero, Catherine M. Dentinger, Jean Pierre Rakotovao, Laurent Kapesa, Haja Andriamiharisoa, Laura C. Steinhardt, Bakoly Randrianarisoa, Reena Sethi, Patricia Gomez, Jocelyn Razafindrakoto, Eliane Razafimandimby, Ralaivaomisa Andrianandraina, Mauricette Nambinisoa Andriamananjara, Aimée Ravaoarinosy, Sedera Aurélien Mioramalala and Barbara Rawlins
    Citation: Malaria Journal 2022 21:212
  34. Nchelenge District in northern Zambia suffers from holoendemic malaria transmission despite a decade of yearly indoor residual spraying (IRS) and insecticide-treated net (ITN) distributions. One hypothesis for...

    Authors: Mary E. Gebhardt, Rachel S. Krizek, Maureen Coetzee, Lizette L. Koekemoer, Yael Dahan-Moss, David Mbewe, James Sichivula Lupiya, Mbanga Muleba, Jennifer C. Stevenson, William J. Moss and Douglas E. Norris
    Citation: Malaria Journal 2022 21:211
  35. The preventive and curative strategies of malaria are based on promoting the use of long-lasting insecticidal nets (LLINs) and treating confirmed cases with artemisinin-based combination therapy. These strateg...

    Authors: El Hadji Diouf, Mbaye Diouf, Constentin Dieme, Isabel Swamidoss, El Hadji Malick Ngom, Massila Wagué Senghor, Modou Mbaye, Abdoulaye Konaté, Youssouph Coulibaly, Dome Tine, Ibrahima Dia, Ellen Marie Dotson, Ousmane Faye and Lassana Konaté
    Citation: Malaria Journal 2022 21:210
  36. Malaria in Cambodia has decreased by 90.8% between 2010 and 2020, driven by the commitment of the National Center for Parasitology, Entomology and Malaria (CNM) and the achievements of the roll-out of a villag...

    Authors: Siv Sovannaroth, Pengby Ngor, Vichka Khy, Julia C. Dunn, Michelle K. Burbach, Sovann Peng, Sarath Mak, Krung Siv, Giulia Manzoni, Jean Olivier Guintran, Luciano Tuseo and Rekol Huy
    Citation: Malaria Journal 2022 21:209
  37. The WHO cone test is one of three tests currently used to evaluate the efficacy of insecticide-treated bed nets (ITNs). It generates two test outputs, knockdown and 24-h mortality, both indicative of immediate...

    Authors: Angela Hughes, Agnes Matope, Mischa Emery, Keith Steen, Gregory Murray, Hilary Ranson, Philip J. McCall and Geraldine M. Foster
    Citation: Malaria Journal 2022 21:208
  38. Independent emergence and spread of artemisinin-resistant Plasmodium falciparum malaria have recently been confirmed in Africa, with molecular markers associated with artemisinin resistance increasingly detected....

    Authors: Frank M. Kagoro, Elizabeth Allen, Aaron Mabuza, Lesley Workman, Ray Magagula, Gerdalize Kok, Craig Davies, Gillian Malatje, Philippe J. Guérin, Mehul Dhorda, Richard J. Maude, Jaishree Raman and Karen I. Barnes
    Citation: Malaria Journal 2022 21:207
  39. Rapid emergence of Plasmodium resistance to anti-malarial drug mainstays has driven a continual effort to discover novel drugs that target different biochemical pathway (s) during infection. Plasma membrane Calci...

    Authors: Puji B. S. Asih, Josephine E. Siregar, Farahana K. Dewayanti, Normalita E. Pravitasari, Ismail E. Rozi, Andita F. M. Rizki, Rifqi Risandi, Kevin N. Couper, Delvac Oceandy and Din Syafruddin
    Citation: Malaria Journal 2022 21:206
  40. Malaria chemoprophylaxis using chloroquine (CQ) and primaquine (PQ) has been administered to resident soldiers in the 3rd Army of Republic of Korea (ROK) to prevent malaria infection since the year 1997. Due t...

    Authors: Jin-Jong Bong, Wonsig Lee, Chan Hee Lee, Quehn Park and Kyung Tae Noh
    Citation: Malaria Journal 2022 21:205
  41. Malaria is an infectious disease considered as one of the biggest causes of mortality in endemic areas. This life-threatening disease needs to be quickly diagnosed and treated. The standard diagnostic tools re...

    Authors: Azza Bouzayene, Rizwana Zaffaroullah, Justine Bailly, Liliane Ciceron, Véronique Sarrasin, Sandrine Cojean, Nicolas Argy, Sandrine Houzé and Valentin Joste
    Citation: Malaria Journal 2022 21:204
  42. An estimated 1.5 billion malaria cases and 7.6 million malaria deaths have been averted globally since 2000; long-lasting insecticidal nets (LLINs) have contributed an estimated 68% of this reduction. Insuffic...

    Authors: Lucy Paintain, Richard Kpabitey, Felix Nyanor-Fosu, Danielle Piccinini Black, Kathryn Bertram, Jayne Webster, Catherine Goodman and Matt Lynch
    Citation: Malaria Journal 2022 21:203
  43. In Burkina Faso, malaria remains the first cause of medical consultation and hospitalization in health centres. First-line case management of malaria in the country’s health facilities is based on the use of a...

    Authors: Denise Hien, Jean Moise Tanga Kaboré, Mohamadou Siribié, Issiaka Soulama, Nouhoun Barry, Adama Baguiya, Alfred Bewendtaoré Tiono, André-Marie Tchouatieu and Sodiomon Bienvenu Sirima
    Citation: Malaria Journal 2022 21:202
  44. Rapid diagnostic tests (RDTs) detecting Plasmodium falciparum histidine-rich protein 2 (HRP2) have been an important tool for malaria diagnosis, especially in resource-limited settings lacking quality microscopy....

    Authors: Khalid B. Beshir, Jonathan B. Parr, Jane Cunningham, Qin Cheng and Eric Rogier
    Citation: Malaria Journal 2022 21:201

    The Correction to this article has been published in Malaria Journal 2022 21:266

  45. India has made considerable progress in malaria reduction over the past two decades, with government-sponsored indoor residual spraying (IRS) and insecticide-treated bed net (ITN) or long-lasting insecticidal ...

    Authors: Mattimi Passah, Carinthia Balabet Nengnong, Mark L. Wilson, Jane M. Carlton, Larry Kharbamon and Sandra Albert
    Citation: Malaria Journal 2022 21:200
  46. Coronavirus disease 2019 (COVID-19) often causes atypical clinical manifestations similar to other infectious diseases. In malaria-endemic areas, the pandemic situation will very likely result in co-infection ...

    Authors: Tri Pudy Asmarawati, Okla Sekar Martani, Bramantono Bramantono and Muhammad Vitanata Arfijanto
    Citation: Malaria Journal 2022 21:199
  47. Malaria in pregnancy doubles the risk of low birthweight; up to 11% of all neonatal deaths in sub-Saharan Africa are associated with malaria in pregnancy. To prevent these and other adverse health consequences...

    Authors: Beth L. Rubenstein, Jobiba Chinkhumba, Ethel Chilima, Collins Kwizombe, Ashley Malpass, Shelby Cash, Katherine Wright, Peter Troell, Humphrey Nsona, Fannie Kachale, Doreen Ali, Evans Kaunda, Sosten Lankhulani, Michael Kayange, Don P. Mathanga, John Munthali…
    Citation: Malaria Journal 2022 21:195

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