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  1. Content type: Research

    Low mefloquine exposure has been shown to contribute to treatment failure in patients with uncomplicated falciparum malaria following a 3-day artesunate–mefloquine combination. The present study aimed to devel...

    Authors: Richard M. Hoglund, Ronnatrai Ruengweerayut and Kesara Na-Bangchang

    Citation: Malaria Journal 2018 17:322

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  2. Content type: Research

    Radical cure of Plasmodium vivax malaria requires treatment with a blood schizonticide and a hypnozoitocide (primaquine) to eradicate the dormant liver stages. There has been uncertainty about the operational eff...

    Authors: Kavitha Saravu, Chaitanya Tellapragada, Shrivathsa Kulavalli, Wilbin Xavier, Shashikiran Umakanth, Gouthami Brahmarouphu, Navyasree Kola Srinivas, Jagadish Puralae Channabasavaiah, Anzil Bava, Abdul Vahab Saadi, Vasudev Guddattu, Kapaettu Satyamoorthy and Krishnamurthy Bhat

    Citation: Malaria Journal 2018 17:321

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  3. Content type: Research

    Malaria remains a public health problem in some countries of Central America. Rapid diagnostic tests (RDTs) are one of the most useful tools to assist in the diagnosis of malaria in remote areas. Since its int...

    Authors: Gustavo Fontecha, Rosa E. Mejía, Engels Banegas, Maria Paz Ade, Lisandro Mendoza, Bryan Ortiz, Isaac Sabillón, Gerardo Alvarado, Gabriela Matamoros and Alejandra Pinto

    Citation: Malaria Journal 2018 17:320

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  4. Content type: Research

    Bats are home to diverse haemosporidian parasites namely Plasmodium and Plasmodium-related. While information is available at a worldwide level, haemosporidian infection in bats from Madagascar is still scarce an...

    Authors: Beza Ramasindrazana, Steven M. Goodman, Najla Dsouli, Yann Gomard, Erwan Lagadec, Milijaona Randrianarivelojosia, Koussay Dellagi and Pablo Tortosa

    Citation: Malaria Journal 2018 17:318

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  5. Content type: Research

    Malaria vectors are increasingly developing resistance to insecticides across Africa. The impact of such resistance on the continued effectiveness of insecticide-based interventions remains unclear due to poor...

    Authors: Benjamin D. Menze, Murielle J. Wondji, William Tchapga, Micareme Tchoupo, Jacob M. Riveron and Charles S. Wondji

    Citation: Malaria Journal 2018 17:317

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  6. Content type: Research

    Malaria rapid diagnostic tests (RDTs) are nowadays widely used in malaria endemic countries as an alternative to microscopy for the diagnosis of malaria. However, quality control of test performance and execut...

    Authors: Francois Kiemde, Marc Christian Tahita, Massa dit Achille Bonko, Petra F. Mens, Halidou Tinto, Michael Boele van Hensbroek and Henk D. F. H. Schallig

    Citation: Malaria Journal 2018 17:316

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  7. Content type: Research

    Malaria was once one of the most serious public health problems in China. However, the disease burden has sharply declined and epidemic areas have shrunk after the implementation of an integrated malaria contr...

    Authors: Jun Feng, Li Zhang, Fang Huang, Jian-Hai Yin, Hong Tu, Zhi-Gui Xia, Shui-Sen Zhou, Ning Xiao and Xiao-Nong Zhou

    Citation: Malaria Journal 2018 17:315

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  8. Content type: Research

    The number of clinical cases of malaria is often recorded in resource constrained or conflict settings as a proxy for disease burden. Interpreting case count data in areas of humanitarian need is challenging d...

    Authors: Joel Hellewell, Patrick Walker, Azra Ghani, Bhargavi Rao and Thomas S. Churcher

    Citation: Malaria Journal 2018 17:312

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  9. Content type: Research

    Severe and fatal vivax malaria is increasingly reported from India. In Mangaluru, southern India, malaria is focused in urban areas and associated with importation by migrant workers. In Wenlock Hospital, the ...

    Authors: Prabhanjan P. Gai, Frank P. Mockenhaupt, Konrad Siegert, Jakob Wedam, Archith Boloor, Suyamindra S. Kulkarni, Rashmi Rasalkar, Arun Kumar, Animesh Jain, Chakrapani Mahabala, Pramod Gai, Shantaram Baliga, Rajeshwari Devi and Damodara Shenoy

    Citation: Malaria Journal 2018 17:313

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  10. Content type: Research

    Malaria is currently the most important human parasitic disease in the world responsible for high morbidity and mortality. Appropriate diagnostic methods are essential for early detection. Microscopy examinati...

    Authors: Ariadna Martín-Díaz, José Miguel Rubio, Juan María Herrero-Martínez, Manolo Lizasoain, José Manuel Ruiz-Giardin, Jerónimo Jaqueti, Juan Cuadros, Gerardo Rojo-Marcos, Pablo Martín-Rabadán, María Calderón, Carolina Campelo, María Velasco and Ana Pérez-Ayala

    Citation: Malaria Journal 2018 17:314

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  11. Content type: Research

    Malaria remains one of the major causes of morbidity and mortality among under-five (U5) children in Nigeria. Though different environmental factors have been assessed to influence the distribution and transmi...

    Authors: Oyewale M. Morakinyo, Folusho M. Balogun and Adeniyi F. Fagbamigbe

    Citation: Malaria Journal 2018 17:311

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  12. Content type: Research

    Malaria in pregnancy has devastating consequences for both the expectant mother and baby. Annually, 88.2 (70%) of the 125.2 million pregnancies in malaria endemic regions occur in the Asia–Pacific region. The ...

    Authors: Jenny Hill, Chandra U. R. Landuwulang, Ansariadi, Jenna Hoyt, Faustina H. Burdam, Irene Bonsapia, Din Syafruddin, Jeanne R. Poespoprodjo, Feiko O. ter Kuile, Rukhsana Ahmed and Jayne Webster

    Citation: Malaria Journal 2018 17:309

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  13. Content type: Research

    Indonesia introduced single screening and treatment (SST) of pregnant women for the control of malaria in pregnancy in 2012. Under this policy pregnant women are screened for malaria at their first antenatal c...

    Authors: Jayne Webster, Ansariadi, Faustina Helena Burdam, Chandra Umbu Reku Landuwulang, Jane Bruce, Jeanne Rini Poespoprodjo, Din Syafruddin, Rukhsana Ahmed and Jenny Hill

    Citation: Malaria Journal 2018 17:310

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  14. Content type: Research

    As South Africa strives to achieve malaria elimination by 2018 (zero local cases) the country needs to strengthen its disease surveillance system by reducing the timeliness from case diagnosis to notification ...

    Authors: Ramokone Ednah Baloyi, Mbavhalelo Bridget Shandukani, Rebecca Graffy, Eunice Misiani, Natalie Mayet, Eric Mabunda, Aaron Mabuza, Bheki Qwabe, Bongani Ngwenyama, Carl Reddy and Devanand Moonasar

    Citation: Malaria Journal 2018 17:308

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  15. Content type: Research

    Malaria is a leading cause of paediatric morbidity and mortality in Uganda. More than half of febrile children in rural areas initially seek care at private clinics and drug shops. These shops are generally un...

    Authors: Lawrence T. Wang, Robert Bwambale, Corinna Keeler, Raquel Reyes, Rabbison Muhindo, Michael Matte, Moses Ntaro, Edgar Mulogo, Radhika Sundararajan and Ross M. Boyce

    Citation: Malaria Journal 2018 17:305

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  16. Content type: Research

    The main goal of this study was to assess the blood feeding behaviour and the contribution Anopheles coluzzii and Anopheles gambiae, 2 sibling species of An. gambiae sensu stricto. present and living in sympatry ...

    Authors: Martin C. Akogbéto, Albert Sourou Salako, Fortuné Dagnon, Rock Aïkpon, Michelle Kouletio, Arthur Sovi and Michel Sezonlin

    Citation: Malaria Journal 2018 17:307

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  17. Content type: Research

    Eave tubes are a type of housing modification that provide a novel way of delivering insecticides to mosquitoes as they attempt to enter the house. The current study reports on a series of semi-field studies a...

    Authors: Antoine M. G. Barreaux, N’Guessan Brou, Alphonsine A. Koffi, Raphaël N’Guessan, Welbeck A. Oumbouke, Innocent Z. Tia and Matthew B. Thomas

    Citation: Malaria Journal 2018 17:306

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  18. Content type: Research

    Ever since it was discovered that zoophilic vectors can transmit malaria, zooprophylaxis has been used to prevent the disease. However, zoopotentiation has also been observed. Thus, the presence of livestock h...

    Authors: Hamzah Hasyim, Meghnath Dhimal, Jan Bauer, Doreen Montag, David A. Groneberg, Ulrich Kuch and Ruth Müller

    Citation: Malaria Journal 2018 17:302

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  19. Content type: Research

    The mechanisms of activation and regulation of T lymphocytes and their cytokines in malaria caused by Plasmodium vivax are complex and poorly understood. Previous data suggest that T cells balance protective imm...

    Authors: Samantha Soares Ourives, Quessi Irias Borges, Diego Sampaio Arantes dos Santos, Eponina Cláudia Magalhães Melo, Rodrigo Medeiros de Souza and Amílcar Sabino Damazo

    Citation: Malaria Journal 2018 17:303

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  20. Content type: Review

    Understanding the life cycle of Plasmodium vivax is fundamental for developing strategies aimed at controlling and eliminating this parasitic species. Although advances in omic sciences and high-throughput techni...

    Authors: Maritza Bermúdez, Darwin Andrés Moreno-Pérez, Gabriela Arévalo-Pinzón, Hernando Curtidor and Manuel Alfonso Patarroyo

    Citation: Malaria Journal 2018 17:301

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  21. Content type: Research

    Plasmodium enolase is a target for the growth neutralizing antibodies. Interestingly, the three invasive stages i.e. sporozoites, merozoites, and ookinetes express this protein on their cell surface. Polyclonal a...

    Authors: Sneha Dutta, Aneesha Tewari, Chinthapalli Balaji, Reena Verma, Anasuya Moitra, Mamta Yadav, Prakhar Agrawal, Dinkar Sahal and Gotam K. Jarori

    Citation: Malaria Journal 2018 17:304

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  22. Content type: Research

    Residual efficacy of indoor residual spray may vary with different spray quality and wall surfaces types. This study evaluated the impact of spray quality and wall surface types on residual efficacy of propoxu...

    Authors: Zerihun Desalegn, Teklu Wegayehu and Fekadu Massebo

    Citation: Malaria Journal 2018 17:300

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  23. Content type: Research

    House improvement and environmental management can significantly improve malaria transmission control in endemic communities. This study assessed the influence of physical characteristics of houses and surroun...

    Authors: Emmanuel W. Kaindoa, Marceline Finda, Jepchirchir Kiplagat, Gustav Mkandawile, Anna Nyoni, Maureen Coetzee and Fredros O. Okumu

    Citation: Malaria Journal 2018 17:298

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    The Correction to this article has been published in Malaria Journal 2018 17:327

  24. Content type: Research

    Much of the extensive research regarding transmission of malaria is underpinned by mathematical modelling. Compartmental models, which focus on interactions and transitions between population strata, have been...

    Authors: Neal R. Smith, James M. Trauer, Manoj Gambhir, Jack S. Richards, Richard J. Maude, Jonathan M. Keith and Jennifer A. Flegg

    Citation: Malaria Journal 2018 17:299

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  25. Content type: Research

    Vivax malaria is a leading public health concern worldwide. Due to the high prevalence of Duffy-negative blood group population, Plasmodium vivax in Africa historically is less attributable and remains a neglecte...

    Authors: Mohammad Rafiul Hoque, Mohammed Mohieldien Abbas Elfaki, Md Atique Ahmed, Seong-Kyun Lee, Fauzi Muh, Musab M. Ali Albsheer, Muzamil Mahdi Abdel Hamid and Eun-Taek Han

    Citation: Malaria Journal 2018 17:297

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  26. Content type: Case study

    Vivax malaria reemerged along the Demilitarized Zone (DMZ), Republic of Korea (ROK), in 1993. While it was hypothesized that vivax malaria would spread throughout the peninsula, nearly all cases were due to ex...

    Authors: Jae Hyoung Im, Kyungmin Huh, Chang-Gyo Yoon, Hyeongtaek Woo, Jin-Soo Lee, Moon-Hyun Chung, Terry A. Klein and Jaehun Jung

    Citation: Malaria Journal 2018 17:295

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  27. Content type: Research

    Malaria continues to be a global burden as the efficacy of most commercial anti-malarial drugs has been compromised by the evolution of parasite resistance. With the urgent need created for the development of ...

    Authors: Zoxolo N. Nyaba, Pretty Murambiwa, Andy R. Opoku, Samson Mukaratirwa, Francis O. Shode and Mthokozisi B. C. Simelane

    Citation: Malaria Journal 2018 17:296

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  28. Content type: Research

    Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections. Knowledge of the metabo...

    Authors: Bharathi Avula, Babu L. Tekwani, Narayan D. Chaurasiya, Pius Fasinu, N. P. Dhammika Nanayakkara, H. M. T. Bhandara Herath, Yan-Hong Wang, Ji-Yeong Bae, Shabana I. Khan, Mahmoud A. Elsohly, James D. McChesney, Peter A. Zimmerman, Ikhlas A. Khan and Larry A. Walker

    Citation: Malaria Journal 2018 17:294

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  29. Content type: Research

    Malaria is an important public health problem in Tanzania. The latest national malaria data suggests rebound of the disease in the country. Anopheles arabiensis, a mosquito species renowned for its resilience aga...

    Authors: Rashid A. Khatib, Prosper P. Chaki, Duo-Quan Wang, Yeromin P. Mlacha, Michael G. Mihayo, Tegemeo Gavana, Ning Xiao, Xiao-Nong Zhou and Salim Abdullah

    Citation: Malaria Journal 2018 17:292

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  30. Content type: Research

    To understand more about changes to the molecular components that occur when host endothelium interacts with Plasmodium falciparum-infected erythrocytes, a combined technique of protein separation (1D Blue-Native...

    Authors: Yang Wu, Simon C. Wagstaff, Saeed A. Al-Harthi and Alister G. Craig

    Citation: Malaria Journal 2018 17:293

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  31. Content type: Research

    In Ethiopia, malaria has declined in the last decade; only a small number of cases have been reported, primarily from hotspots. The contribution of house proximity to water bodies and the role of migration in ...

    Authors: Asmamaw Malede, Kassahun Alemu, Mulugeta Aemero, Sirak Robele and Helmut Kloos

    Citation: Malaria Journal 2018 17:290

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  32. Content type: Research

    The extensive research on community members’ willingness to support malaria interventions ignores the role of psychosocial determinants. This study assesses the impact of individuals’ sense of community (perce...

    Authors: D. Yaw Atiglo, Reuben Tete Larbi, Mawuli Komla Kushitor, Adriana A. E. Biney, Paapa Yaw Asante, Naa Dodua Dodoo and F. Nii-Amoo Dodoo

    Citation: Malaria Journal 2018 17:289

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  33. Content type: Research

    Rodent malaria parasites where the gene encoding circumsporozoite protein (CSP) has been replaced with csp genes from the human malaria parasites, Plasmodium falciparum or Plasmodium vivax, are used as pre-clinic...

    Authors: Catherin Marin-Mogollon, Fiona J. A. van Pul, Shinya Miyazaki, Takashi Imai, Jai Ramesar, Ahmed M. Salman, Beatrice M. F. Winkel, Ahmad Syibli Othman, Hans Kroeze, Severine Chevalley-Maurel, Arturo Reyes-Sandoval, Meta Roestenberg, Blandine Franke-Fayard, Chris J. Janse and Shahid M. Khan

    Citation: Malaria Journal 2018 17:288

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  34. Content type: Correction

    Unfortunately after publication of the original article [1], it came to the author’s attention that there is an error in the caption of Fig. 2.

    Authors: Melchior Kashamuka Mwandagalirwa, Lauren Levitz, Kyaw L. Thwai, Jonathan B. Parr, Varun Goel, Mark Janko, Antoinette Tshefu, Michael Emch, Steven R. Meshnick and Margaret Carrel

    Citation: Malaria Journal 2018 17:287

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    The original article was published in Malaria Journal 2017 16:456

  35. Content type: Research

    The Kingdom of Saudi Arabia is seeking malaria eradication. Malaria transmission has been very low over the last few years. Discovered cases of Plasmodium falciparum infection are assigned a treatment protocol of...

    Authors: Rasha Hassan Soliman, Patricia Garcia-Aranda, Sherine Mohamed Elzagawy, Boshra El-Sayed Hussein, Wael Wahid Mayah, Alexandra Martin Ramirez, Thuy-Huong Ta-Tang and José Miguel Rubio

    Citation: Malaria Journal 2018 17:286

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    The Correction to this article has been published in Malaria Journal 2018 17:335

  36. Content type: Methodology

    Although the use of induced blood stage malaria infection has proven to be a valuable tool for testing the efficacy of vaccines and drugs against Plasmodium falciparum, a limiting factor has been the availability...

    Authors: Rebecca Pawliw, Rebecca Farrow, Silvana Sekuloski, Helen Jennings, Julie Healer, Thuan Phuong, Pri Sathe, Cielo Pasay, Krystal Evans, Alan F. Cowman, Louis Schofield, Nanhua Chen, James McCarthy and Katharine Trenholme

    Citation: Malaria Journal 2018 17:283

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  37. Content type: Research

    Malaria is the leading cause of global paediatric mortality in children below 5 years of age. The number of fatalities has reduced significantly due to an expansion of control interventions but the development...

    Authors: Rachel M. Wiltshire, Christina M. Bergey, Jonathan K. Kayondo, Josephine Birungi, Louis G. Mukwaya, Scott J. Emrich, Nora J. Besansky and Frank H. Collins

    Citation: Malaria Journal 2018 17:285

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  38. Content type: Research

    Since 2006, the artemisinin-based combination therapy (ACT) are recommended to treat uncomplicated malaria including non Plasmodium falciparum malaria in Madagascar. Artesunate–amodiaquine (ASAQ) and artemether–l...

    Authors: Oméga Raobela, Valérie Andriantsoanirina, David Gael Rajaonera, Tovonahary Angelo Rakotomanga, Stéphane Rabearimanana, Fanomezantsoa Ralinoro, Didier Ménard and Arsène Ratsimbasoa

    Citation: Malaria Journal 2018 17:284

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  39. Content type: Methodology

    The study of malaria transmission requires the experimental infection of mosquitoes with Plasmodium gametocytes. In the laboratory, this is achieved using artificial membrane feeding apparatus that simulate body ...

    Authors: Kathrin Witmer, Ellie Sherrard-Smith, Ursula Straschil, Mark Tunnicliff, Jake Baum and Michael Delves

    Citation: Malaria Journal 2018 17:282

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  40. Content type: Research

    Malaria remains endemic in Nigeria despite programmes and policies put in place toward malaria elimination. Long-lasting insecticidal nets have been documented to offer protection from malaria by preventing mo...

    Authors: Stella Babalola, Sulaimon T. Adedokun, Anna McCartney-Melstad, Mathew Okoh, Sola Asa, Ian Tweedie and Andrew Tompsett

    Citation: Malaria Journal 2018 17:280

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  41. Content type: Research

    8-Aminoquinolines such as primaquine clear mature Plasmodium falciparum gametocytes that are responsible for transmission from human to mosquitoes and bring radical cure in Plasmodium vivax by clearing dormant li...

    Authors: Getasew Shitaye, Endalamaw Gadisa, Lynn Grignard, Girma Shumie, Wakweya Chali, Temesgen Menberu, Mulualem Belachew, Getaneh Tegegn, Sagni Challi, Jonathan Curry, Laleta Mahey, Tsegaye Hailu, Hassen Mamo, Menakath Menon, Taye Balcha, Abraham Aseffa…

    Citation: Malaria Journal 2018 17:281

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  42. Content type: Research

    Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong Subregion, an area of relatively low transmission, but has yet to be reported in Africa. A population-based mathematical model was use...

    Authors: Nick Scott, Ricardo Ataide, David P. Wilson, Margaret Hellard, Ric N. Price, Julie A. Simpson and Freya J. I. Fowkes

    Citation: Malaria Journal 2018 17:279

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  43. Content type: Research

    Anopheles sacharovi is a dominant malaria vector species in South Europe and the Middle East which has a highly plastic behaviour at both adult and larval stages. Such plasticity has prevented this species from e...

    Authors: Gleb N. Artemov, Alena I. Velichevskaya, Semen M. Bondarenko, Gayane H. Karagyan, Sargis A. Aghayan, Marine S. Arakelyan, Vladimir N. Stegniy, Igor V. Sharakhov and Maria V. Sharakhova

    Citation: Malaria Journal 2018 17:276

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  44. Content type: Correction

    Following publication of the original article [1], one of the authors flagged that unfortunately their last name, Doltario, was incorrectly spelled as ‘Dotrário’.

    Authors: Andréa Beltrami Doltario, Lucas José Bazzo Menon, Valdes Roberto Bollela, Roberto Martinez, Daniel Cardoso de Almeida e Araújo, Benedito Antônio Lopes da Fonseca and Rodrigo de C. Santana

    Citation: Malaria Journal 2018 17:277

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    The original article was published in Malaria Journal 2016 15:294

  45. Content type: Research

    The rapid process of malaria erythrocyte invasion involves ligand–receptor interactions. Inducing antibodies against specific ligands or receptors that abrogate the invasion process is a key challenge for blo...

    Authors: Fauzi Muh, Seong-Kyun Lee, Mohammad Rafiul Hoque, Jin-Hee Han, Ji-Hoon Park, Egy Rahman Firdaus, Robert W. Moon, Yee Ling Lau and Eun-Taek Han

    Citation: Malaria Journal 2018 17:272

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  46. Content type: Research

    Plasmodium 18S rRNA is a biomarker used to monitor blood-stage infections in malaria clinical trials. Plasmodium sporozoites also express this biomarker, and there is conflicting evidence about how long sporozoit...

    Authors: Sean C. Murphy, Andrew S. Ishizuka, Zachary P. Billman, Tayla M. Olsen, Annette M. Seilie, Ming Chang, Nahum Smith, Vorada Chuenchob, Sumana Chakravarty, B. Kim Lee Sim, Stefan H. I. Kappe, Stephen L. Hoffman and Robert A. Seder

    Citation: Malaria Journal 2018 17:275

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  47. Content type: Research

    The development of an effective malarial vaccine is an urgent need. Most glycosylphosphatidylinositol (GPI)-anchored proteins of Plasmodium parasites are exposed to neutralizing antibodies, and several are advanc...

    Authors: Yang Cheng, Bo Wang, Feng Lu, Jin-Hee Han, Md Atique Ahmed and Eun-Taek Han

    Citation: Malaria Journal 2018 17:273

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