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  1. Content type: Research

    The intimate interaction between the pathophysiology of the human host and the biology of the Plasmodium falciparum parasite results in a wide spectrum of disease outcomes in malaria. Development of severe diseas...

    Authors: Philippa Reuterswärd, Sofia Bergström, Judy Orikiiriza, Elisabeth Lindquist, Sven Bergström, Helene Andersson Svahn, Burcu Ayoglu, Mathias Uhlén, Mats Wahlgren, Johan Normark, Ulf Ribacke and Peter Nilsson

    Citation: Malaria Journal 2018 17:426

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  2. Content type: Research

    A multi-country, community-based trial on scheduled screening and treatment for malaria in pregnancy was conducted in Benin, The Gambia and Burkina Faso. Despite standardized procedures and outcomes, the study...

    Authors: Adélaïde Compaoré, Susan Dierickx, Fatou Jaiteh, Alain Nahum, Towanou Francis Emmanuel Bohissou, Halidou Tinto, Susana Scott, Umberto D’Alessandro, Henk Schallig and Koen Peeters Grietens

    Citation: Malaria Journal 2018 17:425

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  3. Content type: Research

    Major investments have been made since 2001, with intensification of malaria control interventions after 2006. Interventions included free distribution of insecticide-treated nets (ITN) to pregnant women and chil...

    Authors: Kassoum Kayentao, Lia S. Florey, Jules Mihigo, Abdoul Doumbia, Aliou Diallo, Diakalia Koné, Ogobara Doumbo and Erin Eckert

    Citation: Malaria Journal 2018 17:424

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  4. Content type: Research

    The degree to which insecticide-treated net (ITN) supply accounts for age and gender disparities in ITN use among household members is unknown. This study explores the role of household ITN supply in the varia...

    Authors: Bolanle Olapeju, Ifta Choiriyyah, Matthew Lynch, Angela Acosta, Sean Blaufuss, Eric Filemyr, Hunter Harig, April Monroe, Richmond Ato Selby, Albert Kilian and Hannah Koenker

    Citation: Malaria Journal 2018 17:423

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  5. Content type: Case study

    The use of insecticides is the cornerstone of effective malaria vector control. However, the last two decades has seen the ubiquitous use of insecticides, predominantly pyrethroids, causing widespread insectic...

    Authors: Edward K. Thomsen, Charlotte Hemingway, Andy South, Kirsten A. Duda, Claire Dormann, Robert Farmer, Michael Coleman and Marlize Coleman

    Citation: Malaria Journal 2018 17:422

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  6. Content type: Research

    Long-lasting insecticidal nets (LLINs) are a key malaria control intervention. To investigate factors associated with ownership and use of LLINs in Uganda, a cross-sectional community survey was conducted in M...

    Authors: Samuel Gonahasa, Catherine Maiteki-Sebuguzi, Sheila Rugnao, Grant Dorsey, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Amy Lynd, Janet Hemingway, Martin Donnelly, Moses R. Kamya and Sarah G. Staedke

    Citation: Malaria Journal 2018 17:421

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  7. Content type: Research

    Even though malaria is generally on the decline due extensive control and elimination efforts, it still remains a public health problem for over 40% of the world’s population. During the course of malaria infe...

    Authors: Samuel Antwi-Baffour, Ransford Kyeremeh, Dorcas Buabeng, Jonathan Kofi Adjei, Claudia Aryeh, George Kpentey and Mahmood Abdulai Seidu

    Citation: Malaria Journal 2018 17:419

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  8. Content type: Research

    Suriname has experienced a significant change in malaria transmission risk and incidence over the past years. The country is now moving toward malaria elimination. The first objective of this study is to descr...

    Authors: Hélène Hiwat, Beatriz Martínez-López, Hedley Cairo, Loretta Hardjopawiro, Agatha Boerleider, Elisabeth Carmen Duarte and Zaida E. Yadon

    Citation: Malaria Journal 2018 17:418

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  9. Content type: Research

    Multiplex bead assays (MBA) that measure IgG antibodies to the carboxy-terminal 19-kDa sub-unit of the merozoite surface protein 1 (MSP119) are currently used to determine malaria seroprevalence in human populati...

    Authors: Jeffrey W. Priest, Mateusz M. Plucinski, Curtis S. Huber, Eric Rogier, Bunsoth Mao, Christopher J. Gregory, Baltazar Candrinho, James Colborn and John W. Barnwell

    Citation: Malaria Journal 2018 17:417

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  10. Content type: Research

    Plasmodium vivax is the predominant malaria species in northern Mauritania. Molecular data on P. vivax isolates circulating in West Africa are scarce. The present study analysed molecular markers associated with ...

    Authors: Jemila Mint Deida, Yacoub Ould Khalef, Emal Mint Semane, Mohamed Salem Ould Ahmedou Salem, Hervé Bogreau, Leonardo Basco, Ali Ould Mohamed Salem Boukhary and Rachida Tahar

    Citation: Malaria Journal 2018 17:416

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  11. Content type: Research

    The incidence of malaria in the Americas has decreased markedly in recent years. Honduras and the other countries of Mesoamerica and the island of Hispaniola have set the goal of eliminating native malaria by ...

    Authors: Sara Avalos, Rosa E. Mejia, Engels Banegas, Cesar Salinas, Lester Gutierrez, Marcela Fajardo, Suzeth Galo, Alejandra Pinto, Angel Mejia and Gustavo Fontecha

    Citation: Malaria Journal 2018 17:415

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  12. Content type: Research

    Deltamethrin-impregnated, long-lasting insecticidal nets (LLINs) were distributed in the study area from November 2014 to January 2015 to evaluate their impact on malaria transmission in the presence of insect...

    Authors: Madhavinadha Prasad Kona, Raghavendra Kamaraju, Martin James Donnelly, Rajendra Mohan Bhatt, Nutan Nanda, Mehul Kumar Chourasia, Dipak Kumar Swain, Shrity Suman, Sreehari Uragayala, Immo Kleinschmidt and Veena Pandey

    Citation: Malaria Journal 2018 17:414

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  13. Content type: Research

    Resistance of Plasmodium falciparum to anti-malarial drugs has hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of chloroquine-resistant P. falciparum in several countries, inc...

    Authors: Oléfongo Dagnogo, Aristide Berenger Ako, Lacinan Ouattara, Noel Dougba Dago, David N’golo Coulibaly, André Offianan Touré and Joseph Allico Djaman

    Citation: Malaria Journal 2018 17:413

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  14. Content type: Research

    Mutations in the voltage-gated sodium channel at codon 1014 confer knock-down resistance (kdr) to pyrethroids in a wide range of insects. Anopheles gambiae exhibits two mutant alleles at codon 1014, serine and ph...

    Authors: Amy Lynd, Ambrose Oruni, Arjen E. van’t Hof, John C. Morgan, Leon Bwazumo Naego, Dimitra Pipini, Kevin A. O’Kines, Thierry L. Bobanga, Martin J. Donnelly and David Weetman

    Citation: Malaria Journal 2018 17:412

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  15. Content type: Research

    Meghalaya, one of eight states in the northeastern region of India, has been reported to carry a high malaria burden. However, malaria surveillance, epidemiology, and vector studies are sparse, and no reviews ...

    Authors: Anne Kessler, Anna Maria van Eijk, Limalemla Jamir, Catherine Walton, Jane M. Carlton and Sandra Albert

    Citation: Malaria Journal 2018 17:411

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  16. Content type: Research

    Malaria is a major mosquito transmitted, blood-borne parasitic disease that afflicts humans. The disease causes anaemia and other clinical complications, which can lead to death. Plasmodium vivax is known for its...

    Authors: Luis L. Fonseca, Chester J. Joyner, Celia L. Saney, Alberto Moreno, John W. Barnwell, Mary R. Galinski and Eberhard O. Voit

    Citation: Malaria Journal 2018 17:410

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  17. Content type: Research

    Despite the development of resistance to Plasmodium falciparum malaria, sulfadoxine–pyrimethamine is still effective for intermittent preventive treatment of malaria in pregnancy (IPTp). In Tanzania, more than 10...

    Authors: Alphonce I. Marealle, Dennis P. Mbwambo, Wigilya P. Mikomangwa, Manase Kilonzi, Hamu J. Mlyuka and Ritah F. Mutagonda

    Citation: Malaria Journal 2018 17:409

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  18. Content type: Research

    Until very recently, Anopheles were considered naturally unable to host Wolbachia, an intracellular bacterium regarded as a potential biological control tool. Their detection in field populations of Anopheles gam...

    Authors: El Hadji Amadou Niang, Hubert Bassene, Patrick Makoundou, Florence Fenollar, Mylène Weill and Oleg Mediannikov

    Citation: Malaria Journal 2018 17:408

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  19. Content type: Research

    The increase in multidrug resistant Plasmodium falciparum infections threatens the malaria elimination goals in countries within the Greater Mekong Sub-region. A multi-pronged approach assuring access to basic ma...

    Authors: Tiengkham Pongvongsa, Koukeo Phommasone, Bipin Adhikari, Gisela Henriques, Kesinee Chotivanich, Borimas Hanboonkunupakarn, Mavuto Mukaka, Pimnara Peerawaranun, Lorenz von Seidlein, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Mallika Imwong, Paul N. Newton, Pratap Singhasivanon, Mayfong Mayxay…

    Citation: Malaria Journal 2018 17:405

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  20. Content type: Research

    Malaria is a major public health problem in Zambia with an estimated 4 million confirmed cases and 2389 deaths reported in 2015. Efforts to reduce the incidence of malaria are often undermined by a number of f...

    Authors: Miriam Lowa, Lungowe Sitali, Mwiche Siame and Patrick Musonda

    Citation: Malaria Journal 2018 17:404

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  21. Content type: Research

    The detection of submicroscopic infections in low prevalence settings has become an increasingly important challenge for malaria elimination strategies. The current field rapid diagnostic tests (RDTs) for Plasmod...

    Authors: Ihn Kyung Jang, Smita Das, Rebecca S. Barney, Roger B. Peck, Andrew Rashid, Stephane Proux, Emmanuel Arinaitwe, John Rek, Maxwell Murphy, Katherine Bowers, Samuel Boadi, Julie Watson, Francois Nosten, Bryan Greenhouse, Peter L. Chiodini and Gonzalo J. Domingo

    Citation: Malaria Journal 2018 17:403

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  22. Content type: Review

    Over the last 15 years, the majority of malaria drug discovery and development efforts have focused on new molecules and regimens to treat patients with uncomplicated or severe disease. In addition, a number o...

    Authors: Fiona Macintyre, Hanu Ramachandruni, Jeremy N. Burrows, René Holm, Anna Thomas, Jörg J. Möhrle, Stephan Duparc, Rob Hooft van Huijsduijnen, Brian Greenwood, Winston E. Gutteridge, Timothy N. C. Wells and Wiweka Kaszubska

    Citation: Malaria Journal 2018 17:402

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  23. Content type: Research

    The genetic diversity of malaria antigens often results in allele variant-specific immunity, imposing a great challenge to vaccine development. Rhoptry Neck Protein 2 (PvRON2) is a blood-stage antigen that pla...

    Authors: Najara C. Bittencourt, Juliana A. Leite, Ana Beatriz I. E. Silva, Tamirys S. Pimenta, João Luiz Silva-Filho, Gustavo C. Cassiano, Stefanie C. P. Lopes, Joao C. K. dos-Santos, Catarina Bourgard, Helder I. Nakaya, Ana Maria Revorêdo da Silva Ventura, Marcus V. G. Lacerda, Marcelo U. Ferreira, Ricardo L. D. Machado, Letusa Albrecht and Fabio T. M. Costa

    Citation: Malaria Journal 2018 17:401

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  24. Content type: Research

    Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of r...

    Authors: Pauline Byakika-Kibwika, Patience Nyakato, Mohammed Lamorde and Agnes N. Kiragga

    Citation: Malaria Journal 2018 17:400

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  25. Content type: Research

    Few previous retrospective studies suggest that Plasmodium ovale wallikeri seems to have a longer latency period and produces deeper thrombocytopaenia than Plasmodium ovale curtisi. Prospective studies were warra...

    Authors: Gerardo Rojo-Marcos, José Miguel Rubio-Muñoz, Andrea Angheben, Stephane Jaureguiberry, Silvia García-Bujalance, Lina Rachele Tomasoni, Natalia Rodríguez-Valero, José Manuel Ruiz-Giardín, Joaquín Salas-Coronas, Juan Cuadros-González, Magdalena García-Rodríguez, Israel Molina-Romero, Rogelio López-Vélez, Federico Gobbi, María Calderón-Moreno, Esteban Martin-Echevarría…

    Citation: Malaria Journal 2018 17:399

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  26. Content type: Research

    There are concerns that resistance to artemisinin-based combination therapy might emerge in Kenya and sub-Saharan Africa (SSA) in the same pattern as was with chloroquine and sulfadoxine–pyrimethamine. Single ...

    Authors: Peninah Muiruri, Denis W. Juma, Luicer A. Ingasia, Lorna J. Chebon, Benjamin Opot, Bidii S. Ngalah, Jelagat Cheruiyot, Ben Andagalu, Hoseah M. Akala, Venny C. S. Nyambati, Joseph K. Ng’ang’a and Edwin Kamau

    Citation: Malaria Journal 2018 17:398

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  27. Content type: Research

    Behaviour changes in mosquitoes from indoor to outdoor biting result in continuing risk of malaria from outdoor activities, including routine household activities and occasional social and cultural practices a...

    Authors: Irene R. Moshi, Lenore Manderson, Halfan S. Ngowo, Yeromin P. Mlacha, Fredros O. Okumu and Ladislaus L. Mnyone

    Citation: Malaria Journal 2018 17:397

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  28. Content type: Research

    There is limited information on uptake of malaria testing among migrants who are a ‘high-risk’ population for malaria. This was an explanatory mixed-methods study. The quantitative component (a cross sectional...

    Authors: Kyaw Thu Hein, Thae Maung Maung, Kyaw Ko Ko Htet, Hemant Deepak Shewade, Jaya Prasad Tripathy, Swai Mon Oo, Zaw Lin and Aung Thi

    Citation: Malaria Journal 2018 17:396

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  29. Content type: Methodology

    Malaria is still a major health problem in sub-Saharan Africa and south-east Asia, but research on malaria in low-income countries can be a challenge due to the lack of laboratory equipment. In addition, sever...

    Authors: Andrea Maria Summerauer, Lorenzo Colombo, Rodney Ogwang, Christoph Berger, Jan Fehr and Simone Bürgler

    Citation: Malaria Journal 2018 17:395

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  30. Content type: Research

    With the documentation of cases of falciparum malaria negative by rapid diagnostic tests (RDT), though at low frequency from natural isolates in a small pocket of Odisha, it became absolutely necessary to investi...

    Authors: Pallabi Pati, Gunanidhi Dhangadamajhi, Madhusmita Bal and Manoranjan Ranjit

    Citation: Malaria Journal 2018 17:394

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  31. Content type: Research

    Haiti and the Dominican Republic, the only two Caribbean countries with endemic malaria transmission, are committed to eliminating malaria. With a Plasmodium falciparum prevalence under 1% and a highly focal tran...

    Authors: Thomas Druetz, Katherine Andrinopoulos, Louis-Marie Boulos, Michaelle Boulos, Gregory S. Noland, Luccene Desir, Jean Frantz Lemoine and Thomas P. Eisele

    Citation: Malaria Journal 2018 17:393

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  32. Content type: Research

    Despite the success of indoor residual insecticide spraying (IRS) in Africa, particularly in Benin, some gaps of information need to be filled to optimize the effectiveness of this intervention in the perspect...

    Authors: Albert S. Salako, Idelphonse Ahogni, Casimir Kpanou, Arthur Sovi, Roseric Azondekon, André A. Sominahouin, Filémon Tokponnon, Virgile Gnanguenon, Fortuné Dagnon, Laurent Iyikirenga and Martin C. Akogbeto

    Citation: Malaria Journal 2018 17:392

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  33. Content type: Research

    Artemisinin-resistant Plasmodium falciparum has been reported throughout the Greater Mekong subregion and threatens to disrupt current malaria control efforts worldwide. Polymorphisms in kelch13 have been associa...

    Authors: Kimberly F. Breglio, Roberto Amato, Richard Eastman, Pharath Lim, Juliana M. Sa, Rajarshi Guha, Sundar Ganesan, David W. Dorward, Carleen Klumpp-Thomas, Crystal McKnight, Rick M. Fairhurst, David Roberts, Craig Thomas and Anna Katharina Simon

    Citation: Malaria Journal 2018 17:391

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  34. Content type: Research

    Sub-microscopic and asymptomatic infections could be bottlenecks to malaria elimination efforts in Ethiopia. This study determined the prevalence of malaria, and individual and household-level factors associat...

    Authors: Endalew Zemene, Cristian Koepfli, Abebaw Tiruneh, Asnakew K. Yeshiwondim, Dinberu Seyoum, Ming-Chieh Lee, Guiyun Yan and Delenasaw Yewhalaw

    Citation: Malaria Journal 2018 17:390

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  35. Content type: Research

    The Plasmodium falciparum apical membrane antigen-1 (PfAMA1) is considered as an ideal vaccine candidate for malaria control due to its high level of immunogenicity and essential role in parasite survival. Among ...

    Authors: Sahib Gul Afridi, Muhammad Irfan, Habib Ahmad, Muneeba Aslam, Mehwish Nawaz, Muhammad Ilyas and Asifullah Khan

    Citation: Malaria Journal 2018 17:389

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  36. Content type: Research

    Building on the declining trend of malaria in Ethiopia, the Federal Ministry of Health aims to eliminate malaria by 2030. As Plasmodium falciparum and Plasmodium vivax are co-endemic in Ethiopia, the use of prima...

    Authors: Ashenafi Assefa, Ahmed Ali, Wakgari Deressa, Wendimagegn Tsegaye, Getachew Abebe, Heven Sime, Amha Kebede, Daddi Jima, Moges Kassa, Tesfay Abreha, Hiwot Teka, Hiwot Solomon, Joseph Malone, Ya Ping Shi, Zhiyong Zhou, Richard Reithinger…

    Citation: Malaria Journal 2018 17:388

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  37. Content type: Case report

    Post-malaria neurological syndrome (PMNS) is a debated entity, defined by neurological complications following a post-malaria symptom-free period and a negative blood smear. Four cases of PMNS are hereby repor...

    Authors: Yanis Tamzali, Sophie Demeret, Elie Haddad, Hélène Guillot, Eric Caumes and Stéphane Jauréguiberry

    Citation: Malaria Journal 2018 17:387

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  38. Content type: Research

    Determination of the genetic diversity of malaria parasites can inform the intensity of transmission and identify potential deficiencies in malaria control programmes. This study was conducted to characterize ...

    Authors: Hussein Mohammed, Moges Kassa, Kalkidan Mekete, Ashenafi Assefa, Girum Taye and Robert J. Commons

    Citation: Malaria Journal 2018 17:386

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  39. Content type: Research

    The native gut microbiota of Anopheles mosquitoes is known to play a key role in the physiological function of its host. Interestingly, this microbiota can also influence the development of Plasmodium in its host...

    Authors: Devaiah Monnanda Kalappa, Pradeep Annamalai Subramani, Sowmya Kanchanahalli Basavanna, Susanta Kumar Ghosh, Varadharajan Sundaramurthy, Sreehari Uragayala, Satyanarayan Tiwari, Anupkumar R. Anvikar and Neena Valecha

    Citation: Malaria Journal 2018 17:385

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  40. Content type: Research

    The widespread use of artemisinin-based combination therapy (ACT) and long-lasting insecticide-treated nets (LLINs) has led to an impressive decrease of malaria burden these recent years in Africa. However, so...

    Authors: Amélé N. Wotodjo, Souleymane Doucoure, Nafissatou Diagne, Fatoumata Diene Sarr, Philipe Parola, Jean Gaudart and Cheikh Sokhna

    Citation: Malaria Journal 2018 17:384

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  41. Content type: Research

    Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. Th...

    Authors: Chiuan Herng Leow, Katja Fischer, Chiuan Yee Leow, Katleen Braet, Qin Cheng and James McCarthy

    Citation: Malaria Journal 2018 17:383

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  42. Content type: Research

    Liberia is a West African country that needs substantial investment to strengthen its National Malaria Control Programme (NMCP), which was disrupted during the 2014–2016 Ebola epidemic. As elsewhere, Liberian ...

    Authors: Christine K. Tarr-Attia, Quique Bassat, Bondey Breeze-Barry, Dawoh Peter Lansana, Ana Meyer García-Sípido, Adelaida Sarukhan, Maria Maixenchs, Alfredo Mayor and Guillermo Martínez-Pérez

    Citation: Malaria Journal 2018 17:382

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  43. Content type: Research

    Uganda has sought to address leading causes of childhood mortality: malaria, pneumonia and diarrhoea, through integrated community case management (iCCM). The success of this approach relies on community healt...

    Authors: Jana Jarolimova, Stephen Baguma, Palka Patel, Sara Mian-McCarthy, Moses Ntaro, Michael Matte, Jessica Kenney, Shem Bwambale, Edgar Mulogo and Geren Stone

    Citation: Malaria Journal 2018 17:379

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  44. Content type: Research

    Plasmodium falciparum exhibits a high degree of inter-isolate genetic diversity in its variant surface antigen (VSA) families: P. falciparum erythrocyte membrane protein 1, repetitive interspersed family (RIFIN) ...

    Authors: Ellen Bruske, Thomas D. Otto and Matthias Frank

    Citation: Malaria Journal 2018 17:376

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  45. Content type: Research

    The rate of physical deterioration of long-lasting insecticidal nets (LLINs) varies by household practices, net brand and environment. One way to sustain the protection provided by LLINs against malaria is thr...

    Authors: Zawadi M. Mboma, Angel Dillip, Karen Kramer, Hannah Koenker, George Greer and Lena M. Lorenz

    Citation: Malaria Journal 2018 17:375

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  46. Content type: Research

    Malaria is one of the most important parasitic infectious diseases for which almost half of the world’s population is at risk. Although several diagnostic methods are now available to detect the infection, mor...

    Authors: Jeanne Perpétue Vincent, Kanako Komaki-Yasuda, Moritoshi Iwagami, Satoru Kawai and Shigeyuki Kano

    Citation: Malaria Journal 2018 17:373

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