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  1. Mozambique is a malaria endemic country with an estimated prevalence of malaria in children 6–59 months old that is twice as high in rural areas (46.0%) as in urban areas (18.0%). However, only 46.0% of women ...

    Authors: Gerson Afai, Erika Valeska Rossetto, Cynthia Semá Baltazar, Baltazar Candrinho, Abuchahama Saifodine and Rose Zulliger
    Citation: Malaria Journal 2022 21:76
  2. Malaria remains a major public health threat and tools sensitive to detect infections in low malaria transmission areas are needed to progress elimination efforts. Pregnant women are particularly vulnerable to...

    Authors: A. D. V. Tharkeshi T. Dharmaratne, Saber Dini, Katherine O’Flaherty, David J. Price, James Beeson, Rose McGready, Francois Nosten, Freya J. I. Fowkes, Julie A. Simpson and Sophie G. Zaloumis
    Citation: Malaria Journal 2022 21:75
  3. The World Health Organization (WHO) provides protocols for the diagnosis of malaria. One of them is related to the staining process of blood samples to guarantee the correct parasite visualization. Ensuring th...

    Authors: W. M. Fong Amaris, Carol Martinez, Liliana J. Cortés-Cortés and Daniel R. Suárez
    Citation: Malaria Journal 2022 21:74
  4. The STECLA strain of Anopheles albimanus has been in continuous colony for many years and is the reference strain on which genomic studies for the species are based. Recently, the STECLA strain was demonstrated t...

    Authors: Staci M. Dreyer, Kelsey J. Morin, Marla Magaña, Marie Pott, Donovan Leiva, Nicole L. Achee, John P. Grieco and Jefferson A. Vaughan
    Citation: Malaria Journal 2022 21:72
  5. Plasmodium vivax is emerging as the dominant and prevalent species causing malaria in near-elimination settings outside of Africa. Hypnozoites, the dormant liver stage parasite of P. vivax, are undetectable to an...

    Authors: Caitlin Bourke, Eizo Takashima, Li-Jin Chan, Melanie H. Dietrich, Ramin Mazhari, Michael White, Jetsumon Sattabongkot, Wai-Hong Tham, Takafumi Tsuboi, Ivo Mueller and Rhea Longley
    Citation: Malaria Journal 2022 21:71
  6. Rapid diagnostic tests (RDTs) are widely used for malaria diagnosis of both symptomatic and asymptomatic infections. Although RDTs are a reliable and practical diagnostic tool, the sensitivity of histidine-ric...

    Authors: Colleen M. Leonard, Ashenafi Assefa, Jessica N. McCaffery, Camelia Herman, Mateusz Plucinski, Heven Sime, Hussein Mohammed, Amha Kebede, Hiwot Solomon, Mebrahtom Haile, Matt Murphy, Jimee Hwang and Eric Rogier
    Citation: Malaria Journal 2022 21:70
  7. To understand the Plasmodium vivax malaria transmission intensity and to assess the effectiveness of prevention and control measures taken along the China–Myanmar border, a catalytic model was used to calculate t...

    Authors: Meixue Yao, Lishun Xiao, Xiaodong Sun, Zurui Lin, Xiao Hao, Qiong-qiong Bai and De-Hui Yin
    Citation: Malaria Journal 2022 21:69
  8. Health workers’ compliance with outpatient malaria ‘test and treat’ guidelines has improved since 2010 but plateaued from 2014 at suboptimal levels in Kenya. This study examined the factors associated with hig...

    Authors: Beatrice Amboko, Kasia Stepniewska, Beatrice Machini, Philip Bejon, Robert W. Snow and Dejan Zurovac
    Citation: Malaria Journal 2022 21:68
  9. Access to human hosts by Anopheles mosquitoes is a key determinant of vectorial capacity for malaria, but it can be limited by use of long-lasting insecticidal nets (LLINs). In Malawi, pyrethroid-treated LLINs wi...

    Authors: Rex B. Mbewe, John B. Keven, Themba Mzilahowa, Don Mathanga, Mark Wilson, Lauren Cohee, Miriam K. Laufer and Edward D. Walker
    Citation: Malaria Journal 2022 21:67
  10. Anti-malarial drug resistance is still a major threat to malaria elimination in the Great Mekong Sub-region. Plasmodium vivax parasites resistant to anti-malarial drugs are now found in Myanmar. Molecular surveil...

    Authors: Fang Huang, Shigang Li, Peng Tian, Lahpai Ja Seng Pu, Yanwen Cui, Hui Liu, Lianzhi Yang and Dahidam Yaw Bi
    Citation: Malaria Journal 2022 21:66
  11. Over the past decade, three strategies have reduced severe malaria cases and deaths in endemic regions of Africa, Asia and the Americas, specifically: (1) artemisinin-based combination therapy (ACT); (2) insec...

    Authors: Mahamoudou Touré, Moussa Keita, Fousseyni Kané, Daouda Sanogo, Salim Kanté, Drissa Konaté, Ayouba Diarra, Nafomon Sogoba, Mamadou B. Coulibaly, Sekou F. Traoré, Michael Alifrangis, Mahamadou Diakité, Jeffrey G. Shaffer, Donald J. Krogstad and Seydou Doumbia
    Citation: Malaria Journal 2022 21:65
  12. The World Health Organization recommends house screening as a tool for malaria control, yet evidence of the long-term durability, functionality and acceptability of this intervention is lacking. In this study,...

    Authors: Fiona C. Shenton, Musa Jawara, Majo Carrasco-Tenezaca, Jakob Knudsen, Umberto D’Alessandro and Steve W. Lindsay
    Citation: Malaria Journal 2022 21:64
  13. Progress against malaria has stalled and may even be slipping backwards in high-burden countries. This is due to a range of factors including insecticide resistance and mosquito feeding behaviours that limit c...

    Authors: Ross M. Boyce, Enid Muhindo, Emmanuel Baguma, Rabbison Muhindo, Bwambale Shem, Ruthly François, Sam Hawke, Bonnie E. Shook-Sa, Moses Ntaro, Aisha Nalusaji, Dan Nyehangane, Raquel Reyes, Jonathan J. Juliano, Mark J. Siedner, Sarah G. Staedke and Edgar M. Mulogo
    Citation: Malaria Journal 2022 21:63
  14. Malaria continues to be a major public health problem in the Northeastern part of India despite the implementation of vector control measures and changes in drug policies. To develop successful vaccines agains...

    Authors: Tulika Nirmolia, Md. Atique Ahmed, Vinayagam Sathishkumar, Nilanju P. Sarma, Dibya R. Bhattacharyya, Pradyumna K. Mohapatra, Devendra Bansal, Praveen K. Bharti, Rakesh Sehgal, Jagadish Mahanta, Ali A. Sultan, Kanwar Narain and Saurav J. Patgiri
    Citation: Malaria Journal 2022 21:62
  15. The addition of a third anti-malarial drug matching the pharmacokinetic characteristics of the slowly eliminated partner drug in artemisinin-based combination therapy (ACT) has been proposed as new therapeutic...

    Authors: Quique Bassat, Oumou Maïga-Ascofaré, Jürgen May, Jerôme Clain, Ghyslain Mombo-Ngoma, Mirjam Groger, Ayôla A. Adegnika, Jean-Claude Dejon Agobé, Abdoulaye Djimde, Johannes Mischlinger and Michael Ramharter
    Citation: Malaria Journal 2022 21:61
  16. Cerebral malaria is still a major cause of death in children in sub-Saharan Africa. Among survivors, debilitating neurological sequelae can leave children with permanent cognitive impairments and societal stig...

    Authors: Arabella Borgstein, Bo Zhang, Colin Lam, Montfort Bernard Gushu, Alice Wangui Liomba, Albert Malenga, Paul Pensulo, Andrew Tebulo, Dylan S. Small, Terrie Taylor and Karl Seydel
    Citation: Malaria Journal 2022 21:60
  17. A recent trial in Burkina Faso and Mali showed that combining seasonal RTS,S/AS01E malaria vaccination with seasonal malaria chemoprevention (SMC) substantially reduced the incidence of uncomplicated and severe m...

    Authors: Jane Grant, Issaka Sagara, Issaka Zongo, Matthew Cairns, Rakiswendé Serge Yerbanga, Modibo Diarra, Charles Zoungrana, Djibrilla Issiaka, Frédéric Nikièma, Frédéric Sompougdou, Amadou Tapily, Mahamadou Kaya, Alassane Haro, Koualy Sanogo, Abdoul Aziz Sienou, Seydou Traore…
    Citation: Malaria Journal 2022 21:59
  18. Inference of person-to-person transmission networks using surveillance data is increasingly used to estimate spatiotemporal patterns of pathogen transmission. Several data types can be used to inform transmiss...

    Authors: John H. Huber, Michelle S. Hsiang, Nomcebo Dlamini, Maxwell Murphy, Sibonakaliso Vilakati, Nomcebo Nhlabathi, Anita Lerch, Rasmus Nielsen, Nyasatu Ntshalintshali, Bryan Greenhouse and T. Alex Perkins
    Citation: Malaria Journal 2022 21:58
  19. Asymptomatic malaria infections can serve as potential reservoirs for malaria transmission. The density of parasites contained in these infections range from microscopic to submicroscopic densities, making the...

    Authors: Hamza B. Agbana, Eric Rogier, Aminata Lo, Zakaria Abukari, Sophie Jones, Ben Gyan, Michael Aidoo and Linda E. Amoah
    Citation: Malaria Journal 2022 21:57
  20. Nomadic populations in Chad are at increased risk of contracting malaria because of their lifestyle. Being highly mobile they are often excluded from disease control programmes, and access to preventive measur...

    Authors: Azoukalné Moukénet, Beackgoubé Honoré, Helen Smith, Kebféné Moundiné, Wang-Mbe Djonkamla, Sol Richardson, Makido Dormbaye, Ngarkodje Ngarasta and Ibrahima Seck
    Citation: Malaria Journal 2022 21:56
  21. Malaria remains the number one cause of morbidity and mortality in Uganda. In 2009, the United States President’s Malaria Initiative (PMI) funded an indoor residual spraying (IRS) project in 10 mid-northern di...

    Authors: Anthony Nuwa, Janet Oola, Sam Okot Obonyo, Mitra Feldman, Shirah Karungi, Edmound Kertho, David Salandini Odong, Isaac Kimera, Godfrey Magumba, Geofrey Beinomugisha, Alexandra Chitty, James Tibenderana, Jimmy Opigo and Francis Abwaimo
    Citation: Malaria Journal 2022 21:55
  22. Control efforts in Zanzibar reduced the burden of malaria substantially from 2000 to 2015, but re-emergence of falciparum malaria has been observed lately. This study evaluated the prevalence of malaria and pe...

    Authors: Annette Onken, Christel Gill Haanshuus, Mohammed Khamis Miraji, Msafiri Marijani, Kibwana Omar Kibwana, Khamis Ali Abeid, Kristine Mørch, Marianne Reimers, Nina Langeland, Fredrik Müller, Pål A. Jenum and Bjørn Blomberg
    Citation: Malaria Journal 2022 21:54
  23. Malaria is endemic to sub-Saharan African countries. Mass and routine distribution, promotion, and use of ITNs are critical components of malaria prevention programmes. Correct and consistent use of insecticid...

    Authors: E. ‘Kuor Kumoji, Grace N. Awantang, Michael Toso, Diarra Kamara, Thérèse Bleu, Wani Lahai, Musa Sillah-Kanu, Abdul Dosso, Dorothy Achu and Stella Babalola
    Citation: Malaria Journal 2022 21:53
  24. Whole-genome sequencing (WGS) is becoming increasingly helpful to assist malaria control programmes. A major drawback of this approach is the large amount of human DNA compared to parasite DNA extracted from u...

    Authors: Romain Coppée, Atikatou Mama, Véronique Sarrasin, Claire Kamaliddin, Lucie Adoux, Lawrence Palazzo, Nicaise Tuikue Ndam, Franck Letourneur, Frédéric Ariey, Sandrine Houzé and Jérôme Clain
    Citation: Malaria Journal 2022 21:51
  25. Achieving malaria elimination requires the targeting of the human reservoir of infection, including those patients with asymptomatic infection. The objective was to synthesise evidence on the accuracy of the r...

    Authors: Cho Naing, Norah Htet Htet, Saint Nway Aye, Htar Htar Aung, Marcel Tanner and Maxine A. Whittaker
    Citation: Malaria Journal 2022 21:50
  26. Artemisinin-based combination therapy (ACT) has been a mainstay for malaria prevention and treatment. However, emergence of drug resistance has incentivised development of new drugs. Defining the kinetics with...

    Authors: Arya SheelaNair, Aleksandra S. Romanczuk, Rosemary A. Aogo, Rohit Nemai Haldar, Lianne I. M. Lansink, Deborah Cromer, Yandira G. Salinas, R. Kiplin Guy, James S. McCarthy, Miles P. Davenport, Ashraful Haque and David S. Khoury
    Citation: Malaria Journal 2022 21:49
  27. Rwanda has achieved impressive reductions in malaria morbidity and mortality over the past two decades. However, the disruption of essential services due to the current Covid-19 pandemic can lead to a reversal...

    Authors: Dieudonne Hakizimana, Christian Ntizimira, Aimable Mbituyumuremyi, Emmanuel Hakizimana, Hani Mahmoud, Pascal Birindabagabo, Clarisse Musanabaganwa and Diane Gashumba
    Citation: Malaria Journal 2022 21:48
  28. Across the Greater Mekong Subregion, malaria remains a dangerous infectious disease, particularly for people who visit forested areas where residual transmission continues. Because vector control measures offe...

    Authors: Monnaphat Jongdeepaisal, Panarasri Khonputsa, Orathai Prasert, Suphitsara Maneenet, Kulchada Pongsoipetch, Anchalee Jatapai, Chawarat Rotejanaprasert, Prayuth Sudathip, Richard J. Maude and Christopher Pell
    Citation: Malaria Journal 2022 21:47
  29. Community engagement has increasingly received attention in malaria research and programme interventions, particularly as countries aim for malaria elimination. Although community engagement strategies and act...

    Authors: Nils Kaehler, Bipin Adhikari, Phaik Yeong Cheah, Lorenz von Seidlein, Nicholas P. J. Day, Arjen M. Dondorp and Christopher Pell
    Citation: Malaria Journal 2022 21:46
  30. Additional vector control tools are needed to supplement current strategies to achieve malaria elimination and control of Aedes-borne diseases in many settings in Thailand and the Greater Mekong Sub-region. Withi...

    Authors: Patcharawan Sirisopa, Chutipong Sukkanon, Michael J. Bangs, Sutkhet Nakasathien, Jeffrey Hii, John P. Grieco, Nicole L. Achee, Sylvie Manguin and Theeraphap Chareonviriyaphap
    Citation: Malaria Journal 2022 21:44
  31. Cerebral malaria (CM) is associated with sequestration of parasitized red blood cells (PRBCs) in the capillaries. Often, the association of CM with cerebral oedema is related with high mortality rate. Morpholo...

    Authors: Charit Srisook, Supattra Glaharn, Chuchard Punsawad and Parnpen Viriyavejakul
    Citation: Malaria Journal 2022 21:43
  32. The private sector plays a large role in malaria treatment provision in Nigeria. To improve access to, and affordability of, quality-assured artemisinin-based combination therapy (QA-ACT) within this sector, t...

    Authors: Hannah M. Edwards, Rubaiyath Sarwar, Parvez Mahmud, Shekarau Emmanuel, Kolawole Maxwell and James K. Tibenderana
    Citation: Malaria Journal 2022 21:42
  33. Standard dosage regimens of quinine formulated for adult patients with uncomplicated and complicated malaria have been applied for clinical uses in children, pregnant women, and elderly. Since these population...

    Authors: Teerachat Saeheng and Kesara Na-Bangchang
    Citation: Malaria Journal 2022 21:41
  34. Malaria elimination by 2030 is an aim of many countries in the Greater Mekong Sub-region, including Vietnam. However, to achieve this goal and accelerate towards malaria elimination, countries need to determin...

    Authors: Nguyen Ngoc San, Nguyen Xuan Kien, Nguyen Duc Manh, Nguyen Van Thanh, Marina Chavchich, Nguyen Thi Huong Binh, Tran Khanh Long, Kimberly A. Edgel, Eduard Rovira-Vallbona, Michael D. Edstein and Nicholas J. Martin
    Citation: Malaria Journal 2022 21:40
  35. In 2012, seasonal malaria chemoprevention (SMC) was recommended as policy for malaria control by the World Health Organization (WHO) in areas of highly seasonal malaria transmission across the Sahel sub-region...

    Authors: Almahamoudou Mahamar, Kelsey M. Sumner, Brandt Levitt, Betsy Freedman, Aliou Traore, Amadou Barry, Djibrilla Issiaka, Adama B. Dembele, Moussa B. Kanoute, Oumar Attaher, Boubacar N. Diarra, Issaka Sagara, Abdoulaye Djimde, Patrick E. Duffy, Michal Fried, Steve M. Taylor…
    Citation: Malaria Journal 2022 21:39
  36. Since the 1950s, China has transitioned from a malaria pandemic country with tens of millions of annual cases, through phases of local control and elimination, to sustained national malaria elimination efforts...

    Authors: Duo-quan Wang, Xiao-hui Liang, Shen-ning Lu, Wei Ding, Jing Huang, Xin Wen, Shan Lv, Ning Xiao, Lewis Husain and Xiao-Nong Zhou
    Citation: Malaria Journal 2022 21:38
  37. Authors: Chris Ebong, Asadu Sserwanga, Jane Frances Namuganga, James Kapisi, Arthur Mpimbaza, Samuel Gonahasa, Victor Asua, Sam Gudoi, Ruth Kigozi, James Tibenderana, John Bosco Bwanika, Agaba Bosco, Denis Rubahika, Daniel Kyabayinze, Jimmy Opigo, Damian Rutazana…
    Citation: Malaria Journal 2022 21:37

    The original article was published in Malaria Journal 2021 20:484

  38. In sub-Saharan Africa, house design and ventilation affects the number of malaria mosquito vectors entering houses. This study hypothesized that indoor light from a CDC-light trap, visible from outside a hut, ...

    Authors: Arnold S. Mmbando, John Bradley, Deogratius Kazimbaya, Robert Kasubiri, Jakob Knudsen, Doreen Siria, Lorenz von Seidlein, Fredros O. Okumu and Steve W. Lindsay
    Citation: Malaria Journal 2022 21:36
  39. Congenital malaria, which is caused by vertical transmission of malaria parasites, is a potentially fatal condition. Despite Africa’s high malaria burden, congenital malaria is not routinely screened for, and ...

    Authors: Ezinne I. Nwaneli, Chisom A. Nri-ezedi, Kenneth N. Okeke, Emeka S. Edokwe, Sylvia T. Echendu and Kenechukwu K. Iloh
    Citation: Malaria Journal 2022 21:34
  40. Primaquine (PQ) has been used for the radical cure of relapsing Plasmodium vivax malaria for more than 60 years. PQ is also recommended for prophylaxis and prevention of transmission of Plasmodium falciparum. How...

    Authors: Pius S. Fasinu, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, Yan‑Hong Wang, H. M. T. Bandara Herath, Bharathi Avula, James D. McChesney, David Jollow, Larry A. Walker and Babu L. Tekwani
    Citation: Malaria Journal 2022 21:33
  41. Regulatory T cells are known to play a key role to counter balance the protective immune response and immune mediated pathology. However, the role of naturally occurring regulatory cells CD4+CD25+Foxp3+ in malari...

    Authors: Rubika Chauhan, Vikky Awasthi, Reva Sharan Thakur, Veena Pande, Debprasad Chattopadhyay and Jyoti Das
    Citation: Malaria Journal 2022 21:32
  42. Significant progress in malaria prevention during the past two decades has prompted increasing global dialogue on malaria elimination. Recent reviews on malaria strategies have focused mainly on long-lasting i...

    Authors: Sarah Nalinya, David Musoke and Kevin Deane
    Citation: Malaria Journal 2022 21:31
  43. The World Health Organization recommends quinine plus clindamycin as first-line treatment of malaria in the first trimester of pregnancy and as a second-line treatment for uncomplicated falciparum malaria when...

    Authors: Charles O. Obonyo, Elizabeth A. Juma, Vincent O. Were and Bernhards R. Ogutu
    Citation: Malaria Journal 2022 21:30
  44. Although miners are a priority population in malaria elimination in Guyana, scant literature exists on the drivers of malaria-related behaviour. This study explores the relationship between gold miners’ malari...

    Authors: Bolanle Olapeju, Camille Adams, Sean Wilson, Joann Simpson, Gabrielle C. Hunter, TrishAnn Davis, Lyndsey Mitchum, Horace Cox, Kashana James, Jennifer Orkis and J. Douglas Storey
    Citation: Malaria Journal 2022 21:29
  45. Public health initiatives for improving adherence to primaquine based regimens and enhancing effective pharmacovigilance are needed to support the efforts for malaria elimination in real world conditions.

    Authors: Diego Macías Saint-Gerons, Sheila Rodovalho, Ádila Liliane Barros Dias, André Lacerda Ulysses de Carvalho, Andrea Beratarrechea, Wuelton Marcelo Monteiro, Myrna Barata Machado, Cristiano Fernandes da Costa, Marcelo Yoshito Wada, Márcia Helena Maximiano Faria de Almeida, Rayanne Silva de Matos Fonseca, Jady Shayenne Mota Cordeiro, Alinne Paula Rodrigues Antolini, João Altecir Nepomuceno, Karen Fleck, Fernanda Simioni Gasparotto…
    Citation: Malaria Journal 2022 21:28
  46. In areas where malaria is endemic and where trained microscopists are not available, rapid diagnostic tests (RDTs) are needed not only to allow prompt treatment without delay but also to prevent overdiagnosis ...

    Authors: Ayodhia Pitaloka Pasaribu, Irma Sari Nasution, Krisnarta Sembiring, Fahmi Fahmi and Syahril Pasaribu
    Citation: Malaria Journal 2022 21:27
  47. The usefulness of histidine-rich protein-2/3 (HRP2/3)-based rapid diagnostic tests of malaria due to Plasmodium falciparum has been threatened by the appearance of mutant PfHRP2/3 genes. This study was undertaken...

    Authors: Ayalew Jejaw Zeleke, Asrat Hailu, Abebe Genetu Bayih, Migbaru Kefale, Ashenafi Tazebew Amare, Yalewayker Tegegne and Mulugeta Aemero
    Citation: Malaria Journal 2022 21:26

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