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  1. The collection and utilization of surveillance data is essential in monitoring progress towards achieving malaria elimination, in the timely response to increases in malaria case numbers and in the assessment ...

    Authors: Jade D. Rae, Suphak Nosten, Ladda Kajeechiwa, Jacher Wiladphaingern, Daniel M. Parker, Jordi Landier, Aung Myint Thu, Hsa Dah, Aye Be, Win Cho Cho, K.’Nyaw Paw, Eh Shee Paw, Paw Bway Shee, Christ Poe, Chit Nu, Baw Nyaw…
    Citation: Malaria Journal 2022 21:175
  2. Copper is an essential metal for living organisms as a catalytic co-factor for important enzymes, like cytochrome c oxidase the final enzyme in the electron transport chain. Plasmodium falciparum parasites in inf...

    Authors: Abdulmalik Abdullahi Salman and J. P. Dean Goldring
    Citation: Malaria Journal 2022 21:173
  3. Low-level of malaria transmission persist in Zanzibar despite high coverage of core vector control interventions. This study was carried out in hot-spot sites to better understand entomological factors that ma...

    Authors: Revocatus M. Musiba, Brian B. Tarimo, April Monroe, Dickson Msaky, Halfan Ngowo, Kimberly Mihayo, Alex Limwagu, Godlove T. Chilla, Gasper K. Shubis, Ahmada Ibrahim, George Greer, Juma H. Mcha, Khamis A. Haji, Faiza B. Abbas, Abdullah Ali, Fredros O. Okumu…
    Citation: Malaria Journal 2022 21:172
  4. Subclinical infection with Plasmodium falciparum remains highly prevalent, yet diagnosing these often low-density infections remains a challenge. Infections can be subpatent, falling below the limit of detection ...

    Authors: Jason P. Mooney, Sophia M. DonVito, Maimuna Jahateh, Haddy Bittaye, Christian Bottomley, Umberto D’Alessandro and Eleanor M. Riley
    Citation: Malaria Journal 2022 21:171
  5. Despite the introduction of efficacious interventions for malaria control, sub-Saharan Africa continues to bear the highest burden of malaria and its associated effects on vulnerable populations, such as pregn...

    Authors: Matilda Aberese-Ako, Phidelia Doegah, Evelyn Acquah, Pascal Magnussen, Evelyn Ansah, Gifty Ampofo, Dominic Dankwah Agyei, Desmond Klu, Elsie Mottey, Julie Balen, Safiatou Doumbo, Wilfred Mbacham, Ouma Gaye, Margaret Gyapong, Seth Owusu-Agyei and Harry Tagbor
    Citation: Malaria Journal 2022 21:170
  6. The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine ...

    Authors: Warunee Hanpithakpong, Nicholas P. J. Day, Nicholas J. White and Joel Tarning
    Citation: Malaria Journal 2022 21:169
  7. Malaria remains a major cause of morbidity and death among children less than 5 years of age. In Togo, despite intensification of malaria control interventions, malaria remained highly prevalent, with signific...

    Authors: Gountante Kombate, Wakpaouyare Gmakouba, Susana Scott, Komi Ameko Azianu, Didier Koumavi Ekouevi and Marianne A. B. van der Sande
    Citation: Malaria Journal 2022 21:168
  8. Malaria is a major cause of morbidity and mortality worldwide. According to the World Health Organization 2021 malaria report, it is considered to be endemic in 85 countries and territories. Malaria eliminatio...

    Authors: Abtie Abebaw, Yibeltal Aschale, Tadesse Kebede and Asrat Hailu
    Citation: Malaria Journal 2022 21:167
  9. The East Nusa Tenggara province, Indonesia, contributed to 5% of malaria cases nationally in 2020, with other mosquito-borne diseases, such as dengue and filariasis also being endemic. Monitoring of spatial an...

    Authors: Dendi H. Permana, Siti Zubaidah, Lepa Syahrani, Puji B. S. Asih, Din Syafruddin, Ismail E. Rozi, Anggi P. N. Hidayati, Sully Kosasih, Farahana K. Dewayanti, Nia Rachmawati, Rifqi Risandi, Michael J. Bangs, Claus Bøgh, Jenna R. Davidson, Allison L. Hendershot, Timothy A. Burton…
    Citation: Malaria Journal 2022 21:166
  10. The Community-Based Malaria Management (CBMM) strategy, introduced in 2013 and expanded to all health facilities and health posts in Afghanistan by 2016, aimed to deliver rapid diagnostic testing and more time...

    Authors: Sayed Daoud Mahmoodi, Abdul Alim Atarud, Ahmad Walid Sediqi, Sarah Gallalee, Willi McFarland, Temesgen Birara Aynie, Mohmmad Sami Nahzat, Hamida Hamid, Ghulam Qader Qader, Mohammad Shoaib Tamim and Ali Mirzazadeh
    Citation: Malaria Journal 2022 21:165
  11. The World Health Organization World Malaria Report of 2019 indicated an estimated 228 million cases of malaria occurred worldwide in 2018. More than 75% of the total area of Ethiopia is malarious, making malar...

    Authors: Yamlak Gindola, Desalegn Getahun, David Sugerman, Eric Tongren, Ryan Tokarz, Mesfin Wossen, Kassahun Demissie, Etsehiwot Zemelak, Akuma Okugn, Jimmawork Wendimu, Girmay Hailu, Mesfin Tegistu and Dumesa Begna
    Citation: Malaria Journal 2022 21:164
  12. The colonization of mosquitoes susceptible to Plasmodium vivax via direct membrane feeding assay (DMFA) has the potential to significantly advance our knowledge of P. vivax biology, vector-parasite interaction an...

    Authors: Najara A. C. Santos, Alice O. Andrade, Thais C. Santos, Leandro N. Martinez, Amália S. Ferreira, Alessandra S. Bastos, Mirilene M. Martins, José D. C. Pontual, Carolina B. G. Teles, Jansen F. Medeiros and Maisa S. Araújo
    Citation: Malaria Journal 2022 21:163
  13. Migrant populations are at an increased risk of exposure to malaria due to their nature of work and seasonal migration. This study aimed to compare malaria prevention behaviours and care-seeking practices amon...

    Authors: Ye Kyaw Aung, Su Su Zin, Kemi Tesfazghi, Mahesh Paudel, May Me Thet and Si Thu Thein
    Citation: Malaria Journal 2022 21:162
  14. It is often assumed that the population dynamics of the malaria vector Anopheles funestus, its role in malaria transmission and the way it responds to interventions are similar to the more elaborately characteriz...

    Authors: Halfan S. Ngowo, Fredros O. Okumu, Emmanuel E. Hape, Issa H. Mshani, Heather M. Ferguson and Jason Matthiopoulos
    Citation: Malaria Journal 2022 21:161
  15. The development of resistance by Plasmodium falciparum to anti-malarial drugs impedes any benefits of the drug. In addition, absence or delayed availability of current anti-malarial drugs in remote areas has the ...

    Authors: Mary Aigbiremo Oboh, Fatou Faal, Oluwagbemisola Elizabeth Adeniji, Simon Correa, Anthony Uyimulam Amawu, Ekon Ogban, Eva Heinz, Grant Hughes, Martin M. Meremikwu and Alfred Amambua-Ngwa
    Citation: Malaria Journal 2022 21:160
  16. Malaria control relies heavily on the use of anti-malarial drugs and insecticides against malaria parasites and mosquito vectors. Drug and insecticide resistance threatens the effectiveness of conventional mal...

    Authors: Charles Mulamba, Chris Williams, Katharina Kreppel, Jean Bosco Ouedraogo and Ally I. Olotu
    Citation: Malaria Journal 2022 21:159
  17. The most important malaria vectors in sub-Saharan Africa are Anopheles gambiae, Anopheles arabiensis, Anopheles funestus, and Anopheles coluzzii. Of these, An. funestus presently dominates in many settings in eas...

    Authors: Najat F. Kahamba, Marceline Finda, Halfan S. Ngowo, Betwel J. Msugupakulya, Francesco Baldini, Lizette L. Koekemoer, Heather M. Ferguson and Fredros O. Okumu
    Citation: Malaria Journal 2022 21:158
  18. In Brazil, malaria is caused mainly by the Plasmodium vivax and Plasmodium falciparum species. Its transmission occurs in endemic and non-endemic areas. Malaria geography in Brazil has retracted and is now concen...

    Authors: Klauss Kleydmann Sabino Garcia, Amanda Amaral Abrahão, Ana Flávia de Morais Oliveira, Karina Medeiros de Deus Henriques, Anielle de Pina-Costa, André Machado Siqueira and Walter Massa Ramalho
    Citation: Malaria Journal 2022 21:157
  19. Malaria case management relies on World Health Organization (WHO)-recommended artemisinin-based combination therapy (ACT), and a continuous understanding of local community knowledge, attitudes, and practices ...

    Authors: Jean Moise Tanga Kaboré, Mohamadou Siribié, Denise Hien, Issiaka Soulama, Nouhoun Barry, Yacouba Nombré, Frederic Dianda, Adama Baguiya, Alfred Bewendtaoré Tiono, Christian Burri, André-Marie Tchouatieu and Sodiomon Bienvenu Sirima
    Citation: Malaria Journal 2022 21:155
  20. Iron deficiency (ID) is common in malaria-endemic settings. Intermittent preventative treatment of malaria in pregnancy (IPTp) and iron supplementation are core components of antenatal care in endemic regions ...

    Authors: Holger W. Unger, Andie Bleicher, Maria Ome-Kaius, Elizabeth H. Aitken and Stephen J. Rogerson
    Citation: Malaria Journal 2022 21:153
  21. Building on an exercise that identified potential harms from simulated investigational releases of a population suppression gene drive for malaria vector control, a series of online workshops identified nine r...

    Authors: John B. Connolly, John D. Mumford, Debora C. M. Glandorf, Sarah Hartley, Owen T. Lewis, Sam Weiss Evans, Geoff Turner, Camilla Beech, Naima Sykes, Mamadou B. Coulibaly, Jörg Romeis, John L. Teem, Willy Tonui, Brian Lovett, Aditi Mankad, Abraham Mnzava…
    Citation: Malaria Journal 2022 21:152
  22. Targeting the asymptomatic liver stage of Plasmodium infection through chemoprevention could become a key intervention to reduce malaria-associated incidence and mortality.

    Authors: Akash Khandelwal, Francisca Arez, Paula M. Alves, Lassina Badolo, Catarina Brito, Christoph Fischli, Diana Fontinha, Claude Oeuvray, Miguel Prudêncio, Matthias Rottmann, Justin Wilkins, Özkan Yalkinoglu, Wilhelmina M. Bagchus and Thomas Spangenberg
    Citation: Malaria Journal 2022 21:151
  23. Malaria is a potentially fatal disease spread by the bites of Plasmodium-infected Anopheles mosquitoes. Despite long-term efforts to control malaria in Rwanda, malaria incidence increased from 48 to 403 cases/100...

    Authors: Ornella Masimbi, Janna M. Schurer, Ellen Rafferty, Jean D’ Amour Ndahimana and J. Hellen Amuguni
    Citation: Malaria Journal 2022 21:150
  24. The COVID-19 pandemic and its collateral damage severely impact health systems globally and risk to worsen the malaria situation in endemic countries. Malaria is a leading cause of morbidity and mortality in G...

    Authors: Anna-Katharina Heuschen, Alhassan Abdul-Mumin, Martin Adokiya, Guangyu Lu, Albrecht Jahn, Oliver Razum, Volker Winkler and Olaf Müller
    Citation: Malaria Journal 2022 21:149
  25. Species of Plasmodium (Haemosporida, Plasmodiidae) are remarkably diverse haemoparasites. Information on genetic diversity of avian malaria pathogens has been accumulating rapidly, however exo-erythrocytic develo...

    Authors: Helene Pendl, Carolina Hernández-Lara, Jakub Kubacki, Nicole Borel, Sarah Albini and Gediminas Valkiūnas
    Citation: Malaria Journal 2022 21:148
  26. In 2019, the RTS,S/AS01E malaria vaccine was introduced on a pilot basis in six regions of Ghana by the Ministry of Health/Ghana Health Service as part of the WHO-coordinated Malaria Vaccine Implementation Progra...

    Authors: Jane Grant, Thomas Gyan, Francis Agbokey, Jayne Webster, Brian Greenwood and Kwaku Poku Asante
    Citation: Malaria Journal 2022 21:147
  27. “Receptivity” to malaria is a construct developed during the Global Malaria Eradication Programme (GMEP) era. It has been defined in varied ways and no consistent, quantitative definition has emerged over the ...

    Authors: Joshua O. Yukich, Kim Lindblade and Jan Kolaczinski
    Citation: Malaria Journal 2022 21:145
  28. Over a third of the world’s population is at risk of Plasmodium vivax-induced malaria. The unique aspect of the parasite’s biology and interactions with the human host make it harder to control and eliminate the ...

    Authors: Natália S. Ferreira, Jéssica Lorena S. Mathias, Sérgio Roberto L. Albuquerque, Anne Cristine G. Almeida, Ana C. Dantas, Fernanda C. Anselmo, Emerson S. Lima, Marcus Vinicius G. Lacerda, Paulo A. Nogueira, Rajendranath Ramasawmy, Marilda S. Gonçalves and José P. Moura Neto
    Citation: Malaria Journal 2022 21:144
  29. In 2014, the Burkina Faso government launched the Seasonal Malaria Chemoprevention (SMC) programme. Expected benefit was a 75% reduction of all malaria episodes and a 75% drop of severe malaria episodes. This ...

    Authors: Fati Kirakoya-Samadoulougou, Vincent De Brouwere, Arnold Fottsoh Fokam, Mady Ouédraogo and Yazoumé Yé
    Citation: Malaria Journal 2022 21:143
  30. While human cases of Plasmodium knowlesi are now regularly recognized in Southeast Asia, infections with other simian malaria species, such as Plasmodium cynomolgi, are still rare. There has been a handful of cli...

    Authors: Piyaporn Sai-ngam, Kingkan Pidtana, Preeyaporn Suida, Kamonporn Poramathikul, Paphavee Lertsethtakarn, Worachet Kuntawunginn, Sarayut Tadsaichol, Montri Arsanok, Siriporn Sornsakrin, Chaiyaporn Chaisatit, Chaiyawat Mathavarat, Sasikanya Thaloengsok, Parat Boonyarangka, Chadin Thongpiam, Samandra Demons, Brian Vesely…
    Citation: Malaria Journal 2022 21:142
  31. Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast Asia and causes many cases wit...

    Authors: Wenn-Chyau Lee, Fei Wen Cheong, Amirah Amir, Meng Yee Lai, Jia Hui Tan, Wei Kit Phang, Shahhaziq Shahari and Yee-Ling Lau
    Citation: Malaria Journal 2022 21:140
  32. The global malaria burden sometimes obscures that the genus Plasmodium comprises diverse clades with lineages that independently gave origin to the extant human parasites. Indeed, the differences between the huma...

    Authors: Ananias A. Escalante, Axl S. Cepeda and M. Andreína Pacheco
    Citation: Malaria Journal 2022 21:139
  33. During the twentieth century, there was an explosion in understanding of the malaria parasites infecting humans and wild primates. This was built on three main data sources: from detailed descriptive morpholog...

    Authors: Hans-Peter Fuehrer, Susana Campino and Colin J. Sutherland
    Citation: Malaria Journal 2022 21:138
  34. In the Republic of the Congo, malaria represents a major public health problem affecting all age groups. A regular surveillance of the current efficacy of first-line anti-malarial drugs is required in the face...

    Authors: Brice Pembet Singana, Prisca Nadine Casimiro, Brunelle Matondo Diassivi, Simon Charles Kobawila, Jean-Mermoz Youndouka, Leonardo K. Basco, Pascal Ringwald, Sébastien Briolant and Mathieu Ndounga
    Citation: Malaria Journal 2022 21:137
  35. Ghana has adopted and implemented intermittent preventive treatment using sulfadoxine-pyrimethamine (IPTp-SP) and insecticide-treated nets (ITNs) in an antenatal care (ANC) context to prevent malaria among pre...

    Authors: Virtue Fiawokome De-Gaulle, Joseph Kamgno, Verner N. Orish, Agnes Kotoh, Wilfred Mbacham, Harry Tagbor and Pascal Magnussen
    Citation: Malaria Journal 2022 21:136
  36. During the last two decades, researchers have suggested that the changes of malaria cases in African highlands were driven by climate change. Recently, a study claimed that the malaria cases (Plasmodium falciparu...

    Authors: Felipe Augusto Maurin Krsulovic, Timothy Peter Moulton, Mauricio Lima and Fabian Jaksic
    Citation: Malaria Journal 2022 21:135
  37. Artesunate–amodiaquine (ASAQ) and Artemether–lumefantrine (AL) are the recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia. Intermittent preventive treatment with sulfadoxine/pyrimeth...

    Authors: Victor S. Koko, Marian Warsame, Benjamin Vonhm, Moses K. Jeuronlon, Didier Menard, Laurence Ma, Fahn Taweh, Lekilay Tehmeh, Paye Nyansaiye, Oliver J. Pratt, Sei Parwon, Patrick Kamara, Magnus Asinya, Aaron Kollie and Pascal Ringwald
    Citation: Malaria Journal 2022 21:134
  38. Smoke from solid biomass cooking is often stated to reduce household mosquito levels and, therefore, malarial transmission. However, household air pollution (HAP) from solid biomass cooking is estimated to be ...

    Authors: Katherine E. Woolley, Suzanne E. Bartington, Francis D. Pope, Sheila M. Greenfield, Lucy S. Tusting, Malcolm J. Price and G. Neil Thomas
    Citation: Malaria Journal 2022 21:133
  39. Following a 30-year development process, RTS,S/AS01E (GSK, Belgium) is the first malaria vaccine to reach Phase IV assessments. The World Health Organization-commissioned Malaria Vaccine Implementation Programme ...

    Authors: Nicolas Praet, Kwaku Poku Asante, Marie-Cecile Bozonnat, Elaine Jacqueline Akité, Patrick Odum Ansah, Laurence Baril, Owusu Boahen, Yolanda Guerra Mendoza, Valerie Haine, Simon Kariuki, Mathieu Lamy, Kenneth Maleta, Randy Mungwira, Latif Ndeketa, Abraham Oduro, Bernhards Ogutu…
    Citation: Malaria Journal 2022 21:132
  40. The rise in Plasmodium falciparum resistance to dihydroartemisinin–piperaquine (DHA–PPQ) treatment has been documented in the Greater Mekong Subregion with associations with mutations in the P. falciparum chloroq...

    Authors: Nonlawat Boonyalai, Kirakarn Kirativanich, Chatchadaporn Thamnurak, Chantida Praditpol, Brian A. Vesely, Mariusz Wojnarski, John S. Griesenbeck and Norman C. Waters
    Citation: Malaria Journal 2022 21:130
  41. Accurate malaria diagnosis and appropriate treatment at local health facilities are critical to reducing morbidity and human reservoir of infectious gametocytes. The current study assessed the accuracy of mala...

    Authors: Wilfred Ouma Otambo, Julius O. Olumeh, Kevin O. Ochwedo, Edwin O. Magomere, Isaiah Debrah, Collins Ouma, Patrick Onyango, Harrysone Atieli, Wolfgang R. Mukabana, Chloe Wang, Ming-Chieh Lee, Andrew K. Githeko, Guofa Zhou, John Githure, James Kazura and Guiyun Yan
    Citation: Malaria Journal 2022 21:129
  42. Countries in malaria endemic regions are determinedly making an effort to achieve the global malaria elimination goals. In Ethiopia, too, all concerned bodies have given attention to this mission as one of the...

    Authors: Selomon Tefera, Temesgen Bekele, Kefelegn Getahun, Abiyot Negash and Tsige Ketema
    Citation: Malaria Journal 2022 21:128
  43. Roraima state is the northernmost state in Brazil and the primary border-crossing point between Brazil and Venezuela. The uncontrolled surge of malaria in Venezuela, coupled with mass migration of Venezuelans ...

    Authors: Erica Anne Wetzler, Paola Marchesini, Leopoldo Villegas and Sara Canavati
    Citation: Malaria Journal 2022 21:127
  44. Loss of efficacy of diagnostic tests may lead to untreated or mistreated malaria cases, compromising case management and control. There is an increasing reliance on rapid diagnostic tests (RDTs) for malaria di...

    Authors: Sabin S. Nundu, Hiroaki Arima, Shirley V. Simpson, Ben-Yeddy Abel Chitama, Yannick Bazitama Munyeku, Jean-Jacques Muyembe, Toshihiro Mita, Steve Ahuka, Richard Culleton and Taro Yamamoto
    Citation: Malaria Journal 2022 21:126

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