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  1. The transition from malaria control to elimination requires understanding and targeting interventions among high-risk populations. In Vietnam, forest-goers are often difficult to test, treat and follow-up for ...

    Authors: Sara E. Canavati, Gerard C. Kelly, Cesia E. Quintero, Thuan Huu Vo, Long Khanh Tran, Colin Ohrt, Thang Duc Ngo, Duong Thanh Tran and Nicholas J. Martin

    Citation: Malaria Journal 2019 18:435

    Content type: Research

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  2. The immune modulating potential of IL-35 in multiple human disorders has been reported. Consequent upon the recognition of inflammatory cytokine activation and its preponderance for mediating pathology during ...

    Authors: Ramatu Omenesa Bello, Maizaton Atmadini Abdullah, Roslaini Abd Majid, Voon Kin Chin, Mohammed Faruq Abd Rachman Isnadi, Zaid Osama Ibraheem, Mohd Khairi Hussain, Mohammed Garba Magaji and Rusliza Basir

    Citation: Malaria Journal 2019 18:434

    Content type: Research

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  3. Asymptomatic malaria parasites are significant sources of infections for onward malaria transmission. Conventional tools for malaria diagnosis such as microscopy and rapid diagnostic test kits (RDT) have relat...

    Authors: Florence A. Umunnakwe, Emmanuel T. Idowu, Olusola Ajibaye, Blessed Etoketim, Samuel Akindele, Aminat O. Shokunbi, Olubunmi A. Otubanjo, Gordon A. Awandare, Alfred Amambua-Ngwa and Kolapo M. Oyebola

    Citation: Malaria Journal 2019 18:433

    Content type: Research

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  4. Government officials, representatives from malaria endemic communities, and nonprofit, academic, and private sector partners convened at the 2019 Isdell:Flowers Cross Border Malaria Initiative Round Table in L...

    Authors: Alexandra Gordon, Rebecca J. Vander Meulen and Alysse Maglior

    Citation: Malaria Journal 2019 18:432

    Content type: Meeting report

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  5. The development of Plasmodium resistance to the last effective anti-malarial drugs necessitates the urgent development of new anti-malarial therapeutic strategies. To this end, plants are an important source of n...

    Authors: Aissata Camara, Mohamed Haddad, Karine Reybier, Mohamed Sahar Traoré, Mamadou Aliou Baldé, Jade Royo, Alpha Omar Baldé, Philippe Batigne, Mahamane Haidara, Elhadj Saidou Baldé, Agnès Coste, Aliou Mamadou Baldé and Agnès Aubouy

    Citation: Malaria Journal 2019 18:431

    Content type: Research

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  6. Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficacy is threatened by drug resistance, th...

    Authors: Marit van Lenthe, Renske van der Meulen, Maryvonne Lassovski, Adelaide Ouabo, Edwige Bakula, Colette Badio, Deogratias Cibenda, Lucy Okell, Erwan Piriou, Lynn Grignard, Kjerstin Lanke, Bhargavi Rao, Teun Bousema and Cally Roper

    Citation: Malaria Journal 2019 18:430

    Content type: Research

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  7. Imported malaria has been an important challenge for China. Fatality rates from malaria increased in China, particularly in Henan Province, primarily due to malpractice and misdiagnoses in healthcare instituti...

    Authors: Xi-Liang Wang, Jie-Bin Cao, Dan-Dan Li, Dong-Xiao Guo, Cheng-Da Zhang, Xiao Wang, Dan-Kang Li, Qing-Lin Zhao, Xiao-Wen Huang and Wei-Dong Zhang

    Citation: Malaria Journal 2019 18:429

    Content type: Research

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  8. Sample size calculations for cluster randomized trials are a recognized methodological challenge for malaria research in pre-elimination settings. Positively correlated responses from the participants in the s...

    Authors: Pimnara Peerawaranun, Jordi Landier, Francois H. Nosten, Thuy-Nhien Nguyen, Tran Tinh Hien, Rupam Tripura, Thomas J. Peto, Koukeo Phommasone, Mayfong Mayxay, Nicholas P. J. Day, Arjen Dondorp, Nick White, Lorenz von Seidlein and Mavuto Mukaka

    Citation: Malaria Journal 2019 18:428

    Content type: Methodology

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  9. Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of dihydroartemisinin.

    Authors: Annabelle Walz, Didier Leroy, Nicole Andenmatten, Pascal Mäser and Sergio Wittlin

    Citation: Malaria Journal 2019 18:427

    Content type: Research

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  10. The circumsporozoite protein (CSP) of Plasmodium is a key surface antigen that induces antibodies and T-cells, conferring immune protection in animal models and humans. However, much of the work on CSP and immuni...

    Authors: Yevel Flores-Garcia, Sonia M. Herrera, Hugo Jhun, Daniel W. Pérez-Ramos, C. Richter King, Emily Locke, Ramadevi Raghunandan and Fidel Zavala

    Citation: Malaria Journal 2019 18:426

    Content type: Research

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  11. Identifying highly immunogenic blood stage antigens which can work as target for naturally acquired antibodies in different eco-epidemiological settings is an important step for designing malaria vaccine. Bloo...

    Authors: Sonal Kale, Chander P. Yadav, Pavitra N. Rao, Sneh Shalini, Alex Eapen, Harish C. Srivasatava, Surya K. Sharma, Veena Pande, Jane M. Carlton, Om P. Singh and Prashant K. Mallick

    Citation: Malaria Journal 2019 18:425

    Content type: Research

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  12. Malaria remains a major public health problem, affecting mainly low-and middle-income countries. The management of this parasitic disease is challenged by ever increasing drug resistance. This study, investiga...

    Authors: Bayode R. Adegbite, Jean R. Edoa, Yabo J. Honkpehedji, Frejus J. Zinsou, Jean C. Dejon-Agobe, Mirabeau Mbong-Ngwese, Fabrice Lotola-Mougueni, Erik Koehne, Albert Lalremruata, Andrea Kreidenweiss, The T. Nguyen, Jutta Kun, Selidji T. Agnandji, Bertrand Lell, Abdou R. Safiou, Fridia A. Obone Atome…

    Citation: Malaria Journal 2019 18:424

    Content type: Research

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  13. With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-...

    Authors: Arezki Izri, Sandrine Cojean, Claire Leblanc, Yves Cohen, Olivier Bouchaud and Rémy Durand

    Citation: Malaria Journal 2019 18:422

    Content type: Case report

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  14. Malaria extensively leads to mortality and morbidity in endemic regions, and the emergence of drug resistant parasites is alarming. Plant derived synthetic pharmaceutical compounds are found to be a foremost r...

    Authors: Shweta Sinha, Daniela I. Batovska, Bikash Medhi, B. D. Radotra, Ashish Bhalla, Nadezhda Markova and Rakesh Sehgal

    Citation: Malaria Journal 2019 18:421

    Content type: Research

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  15. Routine health information systems can provide near real-time data for malaria programme management, monitoring and evaluation, and surveillance. There are widespread concerns about the quality of the malaria ...

    Authors: George Okello, Sassy Molyneux, Scholastica Zakayo, Rene Gerrets and Caroline Jones

    Citation: Malaria Journal 2019 18:420

    Content type: Research

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  16. Although malaria remains one of the major public health threats in inter-tropical areas, there is limited understanding of imported malaria in children by paediatricians and emergency practitioners in non-ende...

    Authors: Lauren Pull, Jean-Marc Lupoglazoff, Matthew Beardmore, Jean-François Michel, Pierre Buffet, Olivier Bouchaud and Jean-Yves Siriez

    Citation: Malaria Journal 2019 18:419

    Content type: Case study

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  17. Transcriptional profiling of the human immune response to malaria has been used to identify diagnostic markers, understand the pathogenicity of severe disease and dissect the mechanisms of naturally acquired i...

    Authors: Susanne H. Hodgson, Julius Muller, Helen E. Lockstone, Adrian V. S. Hill, Kevin Marsh, Simon J. Draper and Julian C. Knight

    Citation: Malaria Journal 2019 18:418

    Content type: Review

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  18. Mass and continuous distribution channels have significantly increased access to insecticide-treated nets (ITNs) in Ghana since 2000. Despite these gains, a large gap remains between ITN access and use.

    Authors: Collins Stephen Ahorlu, Philip Adongo, Hannah Koenker, Sixte Zigirumugabe, Solomon Sika-Bright, Eric Koka, Philip Teg-Nefaah Tabong, Danielle Piccinini, Sylvester Segbaya, Bolanle Olapeju and April Monroe

    Citation: Malaria Journal 2019 18:417

    Content type: Research

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  19. In the Solomon Island, the dominant malaria vector, Anopheles farauti, is highly anthropophagic and increasingly exophilic and early biting. While long-lasting insecticide-treated nets remain effective against An...

    Authors: Kimberley McLaughlin, Thomas R. Burkot, Jance Oscar, Nigel W. Beebe and Tanya L. Russell

    Citation: Malaria Journal 2019 18:416

    Content type: Research

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  20. Malaria continues to be endemic in the coast and Amazon regions of Ecuador. Clarifying current Plasmodium falciparum resistance in the country will support malaria elimination efforts. In this study, Ecuadorian P...

    Authors: Gabriela Valenzuela, L. Enrique Castro, Julio Valencia-Zamora, Claudia A. Vera-Arias, Petra Rohrbach and Fabián E. Sáenz

    Citation: Malaria Journal 2019 18:415

    Content type: Research

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  21. Many subsistence farmers in rural southeastern Tanzania regularly relocate to distant farms in river valleys to tend to crops for several weeks or months each year. While there, they live in makeshift semi-ope...

    Authors: Johnson K. Swai, Arnold S. Mmbando, Halfan S. Ngowo, Olukayode G. Odufuwa, Marceline F. Finda, Winifrida Mponzi, Anna P. Nyoni, Deogratius Kazimbaya, Alex J. Limwagu, Rukiyah M. Njalambaha, Saidi Abbasi, Sarah J. Moore, Joanna Schellenberg, Lena M. Lorenz and Fredros O. Okumu

    Citation: Malaria Journal 2019 18:414

    Content type: Research

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  22. Malaria infection can present with a wide variety of symptoms, ranging from mild to severe. Plasmodium falciparum isolates in uncomplicated and severe malaria infections may have different parasite genetic profil...

    Authors: Hussein Mohammed, Kedir Hassen, Ashenafi Assefa, Kalkidan Mekete, Gemechu Tadesse, Girum Taye and Robert J. Commons

    Citation: Malaria Journal 2019 18:413

    Content type: Research

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  23. The long-lasting insecticidal nets (LLIN) are effective against prevention of malaria and its utilization has been proven to save lives. Despite the mass distribution of LLIN, Nigeria remains the country with ...

    Authors: Obafemi J. Babalola, Mohammed N. Sambo, Suleiman H. Idris, Ike-Oluwapo O. Ajayi, Olufemi Ajumobi and Patrick Nguku

    Citation: Malaria Journal 2019 18:412

    Content type: Research

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  24. Malawi is midway through its current Malaria Strategic Plan 2017–2022, which aims to reduce malaria incidence and deaths by at least 50% by 2022. Malariometric data are available with health surveillance data ...

    Authors: Katherine E. Battle, Austin Gumbo, Gracious Hamuza, Collins Kwizombe, Akuzike Tauzi Banda, Steven Chipeta, Mphatso D. Phiri, Blessings Kamanga, Jacob Kawonga, Taonga Mafuleka, Ashley Malpass, Phinias Mfune, Mathews Mhango, Lumbani Munthali, Godfrey Silungwe, Memory Siwombo…

    Citation: Malaria Journal 2019 18:411

    Content type: Meeting report

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  25. Increasing numbers of aging individuals with chronic co-morbidities travel to regions where falciparum malaria is endemic. Non-communicable diseases are now leading risk factors for death in such countries. Th...

    Authors: Bodo Hoffmeister and Abner Daniel Aguilar Valdez

    Citation: Malaria Journal 2019 18:410

    Content type: Research

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  26. Haiti and the Dominican Republic (DR) are targeting malaria elimination by 2022. The private health sector has been relatively unengaged in these efforts, even though most primary health care in Haiti is provi...

    Authors: Abigail Sidibe, Alysse Maglior, Carmen Cueto, Ingrid Chen, Arnaud Le Menach, Michelle A. Chang, Thomas P. Eisele, Katherine Andrinopolous, Joseph Cherubin, Jean Frantz Lemoine and Adam Bennett

    Citation: Malaria Journal 2019 18:408

    Content type: Research

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  27. Changes in the natural habitats of insect groups are determined the genetic polymorphisms between individuals. The objective of this study was to establish the genetic structure of the Anopheles coluzzii populati...

    Authors: Arsène Jacques Y. H. Fassinou, Come Z. Koukpo, Razaki A. Ossè, Fiacre R. Agossa, Roseric Azondékon, André Sominahouin, Casimir Kpanou, Hermann Sagbohan, Boulais Yovogan, Martin C. Akogbéto and Michel Sezonlin

    Citation: Malaria Journal 2019 18:407

    Content type: Research

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  28. Malaria epidemiological and immunological data suggest that parasite tolerance wanes in the absence of continuous exposure to the parasite, potentially enhancing pathogenesis. The expansion of control interven...

    Authors: Ruth Aguilar, Joseph J. Campo, Silvia Chicuecue, Pau Cisteró, Alba Català, Leopoldina Luis, Itziar Ubillos, Beatriz Galatas, Pedro Aide, Caterina Guinovart, Gemma Moncunill and Carlota Dobaño

    Citation: Malaria Journal 2019 18:406

    Content type: Research

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  29. Vector control is a key component of malaria prevention. Two major vector control strategies have been implemented in São Tomé and Príncipe (STP), indoor residual spraying (IRS) and outdoor larval control using B...

    Authors: Ying-An Chen, Jih-Ching Lien, Lien-Fen Tseng, Chien-Fu Cheng, Wan-Yu Lin, Hurng-Yi Wang and Kun-Hsien Tsai

    Citation: Malaria Journal 2019 18:405

    Content type: Research

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  30. Malaria remains a significant public health challenge in regions of the world where it is endemic. An unprecedented decline in malaria incidences was recorded during the last decade due to the availability of ...

    Authors: Nasir Tajuddeen and Fanie R. Van Heerden

    Citation: Malaria Journal 2019 18:404

    Content type: Review

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  31. The influx of substandard and falsified medicines is a global public health challenge and its rapid detection is a key solution to the menace. This study used three screening methods and one confirmatory metho...

    Authors: Kwabena Frimpong-Manso Opuni, Henry Nettey, Marvin Adjei Larbi, Salome Naa Amerley Amartey, Gifty Nti, Abraham Dzidonu, Patrick Owusu-Danso, Nicholas Amoah Owusu and Alexander Kwadwo Nyarko

    Citation: Malaria Journal 2019 18:403

    Content type: Research

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  32. Serological data indicating the presence and level of antibodies against infectious disease antigens provides indicators of exposure and transmission patterns in a population. Laboratory testing for large-scal...

    Authors: Eric Rogier, Lotus van den Hoogen, Camelia Herman, Kevin Gurrala, Vena Joseph, Gillian Stresman, Jacquelin Presume, Ithamare Romilus, Gina Mondelus, Tamara Elisme, Ruth Ashton, Michelle Chang, Jean F. Lemoine, Thomas Druetz, Thomas P. Eisele, Alexandre Existe…

    Citation: Malaria Journal 2019 18:402

    Content type: Methodology

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  33. Public sector strategies to promote insecticide-treated net (ITN) access have resulted in increased ITN ownership across sub-Saharan Africa. However, the current status of the private sector distribution chann...

    Authors: Bolanle Olapeju, Ifta Choiriyyah, Kathryn Bertram, Danielle Piccinini, Hunter Harig, Richmond Ato Selby, Matthew Lynch and Hannah Koenker

    Citation: Malaria Journal 2019 18:401

    Content type: Research

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  34. While the utility of parasite genotyping for malaria elimination has been extensively documented in low to moderate transmission settings, it has been less well-characterized in holoendemic regions. High malar...

    Authors: Julia C. Pringle, Amy Wesolowski, Sophie Berube, Tamaki Kobayashi, Mary E. Gebhardt, Modest Mulenga, Mike Chaponda, Thierry Bobanga, Jonathan J. Juliano, Steven Meshnick, William J. Moss, Giovanna Carpi and Douglas E. Norris

    Citation: Malaria Journal 2019 18:400

    Content type: Research

    Published on:

  35. Maintaining the effectiveness of the currently recommended malaria vector control interventions while integrating new interventions will require monitoring key recommended indicators to identify threats to eff...

    Authors: Thomas R. Burkot, Robert Farlow, Myo Min, Effie Espino, Abraham Mnzava and Tanya L. Russell

    Citation: Malaria Journal 2019 18:399

    Content type: Research

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  36. The efficacy and safety of artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DP) against asexual parasites population has been documented. However, the effect of these anti-malarials on sexual p...

    Authors: Protus Omondi, Marion Burugu, Damaris Matoke-Muhia, Edwin Too, Eva A. Nambati, William Chege, Kelvin B. Musyoka, Kelvin Thiongo, Maureen Otinga, Francis Muregi and Francis Kimani

    Citation: Malaria Journal 2019 18:398

    Content type: Research

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  37. Imported malaria is increasing in non-endemic areas due to the increment of international travels, migration and, probably, other unknown factors. The objective of this study was to describe the epidemiologica...

    Authors: Marta Domínguez García, Cristina Feja Solana, Alberto Vergara Ugarriza, Cruz Bartolomé Moreno, Elena Melús Palazón and Rosa Magallón Botaya

    Citation: Malaria Journal 2019 18:397

    Content type: Research

    Published on:

  38. India has committed to eliminate malaria by 2030. The national framework for malaria elimination released by the Government of India plans to achieve this goal through strategic planning in a phased manner. Si...

    Authors: Sarala K. Subbarao, Nutan Nanda, Manju Rahi and Kamaraju Raghavendra

    Citation: Malaria Journal 2019 18:396

    Content type: Review

    Published on:

  39. Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an understudied complication of malaria and is characterized by pulmonary inflammation and disruption of the alveolar-capillary membrane. Its...

    Authors: Thao-Thy Pham, Chuchard Punsawad, Supattra Glaharn, Simon F. De Meyer, Parnpen Viriyavejakul and Philippe E. Van den Steen

    Citation: Malaria Journal 2019 18:395

    Content type: Research

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  40. Despite the extensive endeavours, developing an effective malaria vaccine remains as a great challenge. Apical membrane antigen 1 (AMA-1) located on the merozoite surface of parasites belonging to the genus Plasm...

    Authors: Dong-Hun Lee, Ki-Back Chu, Hae-Ji Kang, Su-Hwa Lee, Manika Chopra, Hyo-Jick Choi, Eun-Kyung Moon, Kyung-Soo Inn and Fu-Shi Quan

    Citation: Malaria Journal 2019 18:394

    Content type: Research

    Published on:

  41. Malaria is among the leading cause of infection in individuals with sickle cell disease (SCD) living in sub-Saharan Africa, including Tanzania. However, after 2005 the standard treatment guidelines (STGs) on m...

    Authors: Esther J. Ndegeulaya, George M. Bwire, Raphael Z. Sangeda, Doreen Mloka, Faustine Tungaraza, Augustino S. Kahere, Fidelis F. Manyaki, Fatuma F. Felician, Manase Kilonzi, Wigilya P. Mikomangwa, Hamu J. Mlyuka, Alphonce I. Marealle, Ritah Mutagonda, Liberata Mwita and Kennedy D. Mwambete

    Citation: Malaria Journal 2019 18:393

    Content type: Research

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  42. Malaria remains as a major global problem, being one of the infectious diseases that engender highest mortality across the world. Due to the appearance of resistance and the lack of an effective vaccine, the s...

    Authors: Guiomar Pérez-Moreno, Paula Sánchez-Carrasco, Luis Miguel Ruiz-Pérez, Nils Gunnar Johansson, Sylke Müller, Beatriz Baragaña, Shahienaz Emma Hampton, Ian Hugh Gilbert, Marcel Kaiser, Sandipan Sarkar, Thiyagamurthy Pandurangan, Vijeesh Kumar and Dolores González-Pacanowska

    Citation: Malaria Journal 2019 18:392

    Content type: Research

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  43. Anti-malarial resistance is, and continues to be a significant challenge in the fight against malaria and a threat to achieving malaria elimination. In Zambia, chloroquine (CQ), a safe, affordable and well-tol...

    Authors: Lungowe Sitali, Mulenga C. Mwenda, John M. Miller, Daniel J. Bridges, Moonga B. Hawela, Elizabeth Chizema-Kawesha, James Chipeta and Bernt Lindtjørn

    Citation: Malaria Journal 2019 18:391

    Content type: Research

    Published on:

  44. Malaria is known to contribute to reduction in productivity through absenteeism as worker-hours are lost thus impacting company productivity and performance. This paper analysed the impact of malaria on produc...

    Authors: Akim Tafadzwa Lukwa, Richard Mawoyo, Karen Nelwin Zablon, Aggrey Siya and Olufunke Alaba

    Citation: Malaria Journal 2019 18:390

    Content type: Research

    Published on:

  45. Biannual mass azithromycin administration to preschool children reduces all-cause mortality, but the mechanism for the effect is not understood. Azithromycin has activity against malaria parasites, and malaria...

    Authors: Catherine E. Oldenburg, Abdou Amza, Gretchen Cooley, Boubacar Kadri, Beido Nassirou, Benjamin F. Arnold, Philip J. Rosenthal, Kieran S. O’Brien, Sheila K. West, Robin L. Bailey, Travis C. Porco, Jeremy D. Keenan, Thomas M. Lietman and Diana L. Martin

    Citation: Malaria Journal 2019 18:389

    Content type: Research

    Published on:

  46. The genetic complexity and the existence of several polymorphisms in parasites are the major hindrances for the malaria control programmes of the country. The genetic profiling in the parasite populations in I...

    Authors: Amit Kumar, Shri Pat Singh, Rajendra Bhatt and Vineeta Singh

    Citation: Malaria Journal 2019 18:385

    Content type: Research

    Published on:

  47. Knockdown resistance (kdr) is a well-characterized target-site insecticide resistance mechanism that is associated with DDT and pyrethroid resistance. Even though insecticide resistance to pyrethroids and DDT ...

    Authors: Lorena I. Orjuela, Diego A. Álvarez-Diaz, Juliana A. Morales, Nelson Grisales, Martha L. Ahumada, Juan Venegas H, Martha L. Quiñones and María F. Yasnot

    Citation: Malaria Journal 2019 18:384

    Content type: Research

    Published on:

  48. Long-lasting insecticidal nets (LLINs) treated with pyrethroids are the foundation of malaria control in sub-Saharan Africa. Rising pyrethroid resistance in vectors, however, has driven the development of alte...

    Authors: Kobié H. Toé, Frank Mechan, Julie-Anne A. Tangena, Marion Morris, Joanna Solino, Emile F. S. Tchicaya, Alphonse Traoré, Hanafy Ismail, James Maas, Natalie Lissenden, Margaret Pinder, Steve W. Lindsay, Alfred B. Tiono, Hilary Ranson and N’Falé Sagnon

    Citation: Malaria Journal 2019 18:383

    Content type: Research

    Published on:

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